CCL5 cDNA ORF clone, Sus scrofa(Pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCL5
Entrez Gene ID	396613
Full Name	C-C motif chemokine ligand 5
Synonyms	RANTES,SCYA5,SIS-delta
Gene Type	protein-coding
Organism	Sus scrofa(Pig)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001129946.1	NP_001123418.1	C-C motif chemokine 5 precursor
XM_013989948.1	XP_013845402.1	C-C motif chemokine 5 isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Haemophilus parasuis infection activates chemokine RANTES in PK-15 cells.
Chen Y, Zhou S, Hua K, Xiao H, Li Z, Liu M, Luo R, Bi D, Zhou R, Jin H
Molecular immunology67(2 Pt B)661-6(2015 Oct)

Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced RANTES transcription in PK-15 cells.
Wang D, Fang L, Bi J, Chen Q, Cao L, Luo R, Chen H, Xiao S
Virus genes42(3)388-93(2011 Jun)

Molecular cloning of the porcine RANTES promoter: functional characterization of dsDNA/dsRNA response elements in PK-15 cells.
Wang D, Fang L, Li P, Chen Q, Luo R, Chen H, Xiao S
Developmental and comparative immunology35(3)345-51(2011 Mar)

Porcine reproductive and respiratory syndrome virus (PRRSV) infection activates chemokine RANTES in MARC-145 cells.
Wang Y, Luo R, Fang L, Wang D, Bi J, Chen H, Xiao S
Molecular immunology48(4)586-91(2011 Jan)

PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Uenishi H, Eguchi-Ogawa T, Shinkai H, Okumura N, Suzuki K, Toki D, Hamasima N, Awata T
Nucleic acids research35(Database issue)D650-3(2007 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results represent an important molecular mechanism whereby H. parasuis induced RANTES in the inflammatory response.
Title: Haemophilus parasuis infection activates chemokine RANTES in PK-15 cells.

Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced RANTES transcription.
Title: Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced RANTES transcription in PK-15 cells.

we cloned the nucleotide sequence of the 5'-flanking region of the porcine RANTES (poRANTES) gene and characterized the regulatory elements that activate transcription
Title: Molecular cloning of the porcine RANTES promoter: functional characterization of dsDNA/dsRNA response elements in PK-15 cells.

The Toll-like receptor signaling pathway is involved in porcine reproductive and respiratory syndrome virus-induced RANTES activation.
Title: Porcine reproductive and respiratory syndrome virus (PRRSV) infection activates chemokine RANTES in MARC-145 cells.

These results suggest that porcine RANTES can play an important role in xenotransplant rejection, through participating in the interaction between porcine endothelial cells and human monocytes.
Title: Molecular characterization of miniature porcine RANTES and its chemotactic effect on human mononuclear cells.

The following CCL5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCL5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSe29136	NM_001129946.1 Latest version!	Sus scrofa C-C motif chemokine ligand 5 (CCL5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OSe29136	XM_013989948.1 Latest version!	Sus scrofa chemokine (C-C motif) ligand 5 (CCL5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCL5 ( NM_001129946.1 ) cDNA ORF clone, Sus scrofa(Pig) -> NP_001123418.1 Sus scrofa C-C motif chemokine ligand 5 (CCL5), mRNA.

Price & Availability↑

CloneID	OSe29136
Clone ID Related Accession (Same CDS sequence)	NM_001129946.1 , XM_013989948.1
Accession Version	NM_001129946.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 276bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Sus scrofa(pig)
Product	C-C motif chemokine 5 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from DQ372066.1. ##Evidence-Data-START## Transcript exon combination :: DQ372066.1, CJ013948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1876824, SAMEA1876852 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGTCT CCACCGCTGC CCTTGCTGTC ATCCTCGCCA TGGCCGCCCT CTGCGCTCCA 
GCATCAGCCT CCCCATATGC CTCGGACACC ACACCCTGCT GTTTTTCCTA CCTCTCCCGC 
CCGCTGCCCC GCGCCCACCT CCAGGAATAT TTCTACACCA GCAGCAAGTG CTCCATGGCA 
GCAGTCGTCT TTATCACCAG AAAGAACCGC CAGGTGTGTG CCAACCCAGA GAAGAAATGG 
GTGCGGGAGT ACATCAACTC CTTGGAGTTG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001123418.1
CDS	61..336
Translation	MKVSTAALAVILAMAALCAPASASPYASDTTPCCFSYLSRPLPRAHLQEYFYTSSKCSMAAVVFITRKNRQVCANPEKKWVREYINSLELS

Target ORF information:

RefSeq Version	NM_001129946.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa C-C motif chemokine ligand 5 (CCL5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001129946.1

ORF Insert Sequence:

ATGAAGGTCT CCACCGCTGC CCTTGCTGTC ATCCTCGCCA TGGCCGCCCT CTGCGCTCCA 
GCATCAGCCT CCCCATATGC CTCGGACACC ACACCCTGCT GTTTTTCCTA CCTCTCCCGC 
CCGCTGCCCC GCGCCCACCT CCAGGAATAT TTCTACACCA GCAGCAAGTG CTCCATGGCA 
GCAGTCGTCT TTATCACCAG AAAGAACCGC CAGGTGTGTG CCAACCCAGA GAAGAAATGG 
GTGCGGGAGT ACATCAACTC CTTGGAGTTG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL5 ( XM_013989948.1 ) cDNA ORF clone, Sus scrofa(Pig) -> XP_013845402.1 Sus scrofa chemokine (C-C motif) ligand 5 (CCL5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OSe29136
Clone ID Related Accession (Same CDS sequence)	NM_001129946.1 , XM_013989948.1
Accession Version	XM_013989948.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 276bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-10
Organism	Sus scrofa(Pig)
Product	C-C motif chemokine 5 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003535892.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGTCT CCACCGCTGC CCTTGCTGTC ATCCTCGCCA TGGCCGCCCT CTGCGCTCCA 
GCATCAGCCT CCCCATATGC CTCGGACACC ACACCCTGCT GTTTTTCCTA CCTCTCCCGC 
CCGCTGCCCC GCGCCCACCT CCAGGAATAT TTCTACACCA GCAGCAAGTG CTCCATGGCA 
GCAGTCGTCT TTATCACCAG AAAGAACCGC CAGGTGTGTG CCAACCCAGA GAAGAAATGG 
GTGCGGGAGT ACATCAACTC CTTGGAGTTG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_013845402.1
CDS	334..609
Translation	MKVSTAALAVILAMAALCAPASASPYASDTTPCCFSYLSRPLPRAHLQEYFYTSSKCSMAAVVFITRKNRQVCANPEKKWVREYINSLELS

Target ORF information:

RefSeq Version	XM_013989948.1
Organism	Sus scrofa(Pig)
Definition	Sus scrofa chemokine (C-C motif) ligand 5 (CCL5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_013989948.1

ORF Insert Sequence:

ATGAAGGTCT CCACCGCTGC CCTTGCTGTC ATCCTCGCCA TGGCCGCCCT CTGCGCTCCA 
GCATCAGCCT CCCCATATGC CTCGGACACC ACACCCTGCT GTTTTTCCTA CCTCTCCCGC 
CCGCTGCCCC GCGCCCACCT CCAGGAATAT TTCTACACCA GCAGCAAGTG CTCCATGGCA 
GCAGTCGTCT TTATCACCAG AAAGAACCGC CAGGTGTGTG CCAACCCAGA GAAGAAATGG 
GTGCGGGAGT ACATCAACTC CTTGGAGTTG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Haemophilus parasuis infection activates chemokine RANTES in PK-15 cells.
Molecular immunology67(2 Pt B)661-6(2015 Oct)
Chen Y,Zhou S,Hua K,Xiao H,Li Z,Liu M,Luo R,Bi D,Zhou R,Jin H

Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced RANTES transcription in PK-15 cells.
Virus genes42(3)388-93(2011 Jun)
Wang D,Fang L,Bi J,Chen Q,Cao L,Luo R,Chen H,Xiao S

Molecular cloning of the porcine RANTES promoter: functional characterization of dsDNA/dsRNA response elements in PK-15 cells.
Developmental and comparative immunology35(3)345-51(2011 Mar)
Wang D,Fang L,Li P,Chen Q,Luo R,Chen H,Xiao S

Porcine reproductive and respiratory syndrome virus (PRRSV) infection activates chemokine RANTES in MARC-145 cells.
Molecular immunology48(4)586-91(2011 Jan)
Wang Y,Luo R,Fang L,Wang D,Bi J,Chen H,Xiao S

PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Nucleic acids research35(Database issue)D650-3(2007 Jan)
Uenishi H,Eguchi-Ogawa T,Shinkai H,Okumura N,Suzuki K,Toki D,Hamasima N,Awata T