Syngr2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Syngr2
Entrez Gene ID	89815
Full Name	synaptogyrin 2
General protein information	Preferred Names synaptogyrin 2 Names synaptogyrin-2 cellugyrin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.2
Summary	ubiquitously expressed synaptogyrin isoform; undergoes tyrosine phosphorylation by pp60c-src; may play a role in membrane trafficking [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053553.1	NP_446005.1	synaptogyrin-2

Pathways from BioSystems

Homologies

	SYNGR2	XP_001107757.1
Homo sapiens (human)	SYNGR2	NP_004701.1
Pan troglodytes (chimpanzee)	SYNGR2	XP_001145116.2
Bos taurus (cattle)	SYNGR2	NP_001093828.1
Rattus norvegicus (Norway rat)	Syngr2	NP_446005.1
Xenopus tropicalis (tropical clawed frog)	syngr2	NP_001006785.1
Canis lupus familiaris (dog)	SYNGR2	NP_001239510.1
Mus musculus (house mouse)	Syngr2	NP_033330.1
Gallus gallus (chicken)	SYNGR2	XP_003642411.2
Danio rerio (zebrafish)	syngr2a	NP_001074054.1
Danio rerio (zebrafish)	LOC100537807	XP_003199582.1
Danio rerio (zebrafish)	syngr2b	XP_696934.1

Gene Ontology
Bibliography

Related articles in PubMed

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)

Cellugyrin induces biogenesis of synaptic-like microvesicles in PC12 cells.
Belfort GM, Bakirtzi K, Kandror KV
The Journal of biological chemistry280(8)7262-72(2005 Feb)

Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.
Belfort GM, Kandror KV
The Journal of biological chemistry278(48)47971-8(2003 Nov)

Synaptogyrins regulate Ca2+-dependent exocytosis in PC12 cells.
Sugita S, Janz R, S?dhof TC
The Journal of biological chemistry274(27)18893-901(1999 Jul)

Cellugyrin, a novel ubiquitous form of synaptogyrin that is phosphorylated by pp60c-src.
Janz R, S?dhof TC
The Journal of biological chemistry273(5)2851-7(1998 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

small conserved hydrophobic hairpins in the first luminal loop and the carboxyl terminus of cellugyrin were found to be critical for the formation of SLMVs
Title: Cellugyrin induces biogenesis of synaptic-like microvesicles in PC12 cells.

Cellugyrin and synaptogyrin have roles in facilitating targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment
Title: Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.

The following Syngr2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Syngr2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09874	NM_053553.1 Latest version!	Rattus norvegicus synaptogyrin 2 (Syngr2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Syngr2 ( NM_053553.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446005.1 Rattus norvegicus synaptogyrin 2 (Syngr2), mRNA.

Price & Availability↑

CloneID	ORa09874
Clone ID Related Accession (Same CDS sequence)	NM_053553.1
Accession Version	NM_053553.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 705bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	synaptogyrin-2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF039085.1. ##Evidence-Data-START## Transcript exon combination :: AF039085.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCCTTGA GGGTCGGCGG CGACGGCGAC ATGGAGAGCG GGGCCTATGG CGCGGCCAAC 
GCGGGCGGCT CCTTCGACCT GCGGCGCTAT GTGTCCCAGC CTCAGGTGGT GACACGCCTC 
GTGAGCATGG TCTTGGCCTT GATCGTATTC TCCTGCATCT TCGGCGAGGG CTACATCAAC 
CTTCACTCAT CTGACCAGCT ACACTGTGTG TTCAACCGGA ACGAAGATGC CTGCCGCTAC 
GGCAGTGCCA TTGGGGTGCT GGCCTTCCTG GCCTCAGCCT TCTTCCTTGT GGTGGATGCG 
TTTTTCTCTC AGATAAGCAA TGCCACTGAC CGCAAGTATC TGGTCATTGG TGACCTGCTC 
TTCTCAGCTC TCTGGACCTT CCTGTGGTTT GTCGGTTTCT GCTTTCTGAC CAACCAGTGG 
GCAGCCACCA AACCTGATGA CGTGTTGGTG GGAGCAGACT CAGCCCGGGC TGCCATCACC 
TTCAGTTTCT TCTCCATCTT CTCCTGGGGT GTGCTGGCCT CCCTGGCCTA CCAGCGTTAC 
AAGGCTGGAG TGGATGCCTT CATTCAGAAC TATGTGGACC CCACGCCGGA TCCCACCACA 
GCCTACGCCT CCTACCCTAG TGCCTCGGTG GAAAACTACC AGCAGCCGCC CTTCACCCAG 
AATGTGGAGA CTACTGAGGG CTACCAGCCT CCCCCAGTGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446005.1
CDS	154..858
Translation	MPLRVGGDGDMESGAYGAANAGGSFDLRRYVSQPQVVTRLVSMVLALIVFSCIFGEGYINLHSSDQLHCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKPDDVLVGADSARAAITFSFFSIFSWGVLASLAYQRYKAGVDAFIQNYVDPTPDPTTAYASYPSASVENYQQPPFTQNVETTEGYQPPPVY

Target ORF information:

RefSeq Version	NM_053553.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus synaptogyrin 2 (Syngr2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053553.1

ORF Insert Sequence:

ATGCCCTTGA GGGTCGGCGG CGACGGCGAC ATGGAGAGCG GGGCCTATGG CGCGGCCAAC 
GCGGGCGGCT CCTTCGACCT GCGGCGCTAT GTGTCCCAGC CTCAGGTGGT GACACGCCTC 
GTGAGCATGG TCTTGGCCTT GATCGTATTC TCCTGCATCT TCGGCGAGGG CTACATCAAC 
CTTCACTCAT CTGACCAGCT ACACTGTGTG TTCAACCGGA ACGAAGATGC CTGCCGCTAC 
GGCAGTGCCA TTGGGGTGCT GGCCTTCCTG GCCTCAGCCT TCTTCCTTGT GGTGGATGCG 
TTTTTCTCTC AGATAAGCAA TGCCACTGAC CGCAAGTATC TGGTCATTGG TGACCTGCTC 
TTCTCAGCTC TCTGGACCTT CCTGTGGTTT GTCGGTTTCT GCTTTCTGAC CAACCAGTGG 
GCAGCCACCA AACCTGATGA CGTGTTGGTG GGAGCAGACT CAGCCCGGGC TGCCATCACC 
TTCAGTTTCT TCTCCATCTT CTCCTGGGGT GTGCTGGCCT CCCTGGCCTA CCAGCGTTAC 
AAGGCTGGAG TGGATGCCTT CATTCAGAAC TATGTGGACC CCACGCCGGA TCCCACCACA 
GCCTACGCCT CCTACCCTAG TGCCTCGGTG GAAAACTACC AGCAGCCGCC CTTCACCCAG 
AATGTGGAGA CTACTGAGGG CTACCAGCCT CCCCCAGTGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Buschow SI,van Balkom BW,Aalberts M,Heck AJ,Wauben M,Stoorvogel W

Cellugyrin induces biogenesis of synaptic-like microvesicles in PC12 cells.
The Journal of biological chemistry280(8)7262-72(2005 Feb)
Belfort GM,Bakirtzi K,Kandror KV

Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.
The Journal of biological chemistry278(48)47971-8(2003 Nov)
Belfort GM,Kandror KV

Synaptogyrins regulate Ca2+-dependent exocytosis in PC12 cells.
The Journal of biological chemistry274(27)18893-901(1999 Jul)
Sugita S,Janz R,S?dhof TC

Cellugyrin, a novel ubiquitous form of synaptogyrin that is phosphorylated by pp60c-src.
The Journal of biological chemistry273(5)2851-7(1998 Jan)
Janz R,S?dhof TC