Cox4i2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cox4i2
Entrez Gene ID	84683
Full Name	cytochrome c oxidase subunit 4i2
Synonyms	Cox4b,CoxIV-2
General protein information	Preferred Names cytochrome c oxidase subunit 4i2 Names cytochrome c oxidase subunit 4 isoform 2, mitochondrial COX IV-2 cytochrome c oxidase subunit IV isoform 2 (lung) cytochrome c oxidase, subunit 4b cytochrome c oxidase, subunit IVb
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q41
Summary	subunit of cytochrome c-oxidase, plays a role in cytochrome c-oxidase regulation and electron transport [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017592078.1	XP_017447567.1	cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X1
XM_017592079.1	XP_017447568.1	cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X2
NM_053472.1	NP_445924.1	cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform 2 precursor
XM_006235280.3	XP_006235342.1	cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X3
XM_017592080.1	XP_017447569.1	cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	COX4I2	XP_542949.3
Rattus norvegicus (Norway rat)	Cox4i2	NP_445924.1
Pan troglodytes (chimpanzee)	LOC469913	XP_525298.2
Xenopus tropicalis (tropical clawed frog)	cox4i2	NP_001016945.1
	COX4I2	XP_001110371.1
Mus musculus (house mouse)	Cox4i2	NP_444321.1
Homo sapiens (human)	COX4I2	NP_115998.2
Bos taurus (cattle)	COX4I2	NP_001180115.1

Gene Ontology
Bibliography

Related articles in PubMed

Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2.
Aras S, Pak O, Sommer N, Finley R Jr, H?ttemann M, Weissmann N, Grossman LI
Nucleic acids research41(4)2255-66(2013 Feb)

Protein phosphorylation and prevention of cytochrome oxidase inhibition by ATP: coupled mechanisms of energy metabolism regulation.
Acin-Perez R, Gatti DL, Bai Y, Manfredi G
Cell metabolism13(6)712-9(2011 Jun)

Exocrine pancreatic insufficiency, dyserythropoeitic anemia, and calvarial hyperostosis are caused by a mutation in the COX4I2 gene.
Shteyer E, Saada A, Shaag A, Al-Hijawi FA, Kidess R, Revel-Vilk S, Elpeleg O
American journal of human genetics84(3)412-7(2009 Mar)

Undernutrition during suckling in rats elevates plasma adiponectin and its receptor in skeletal muscle regardless of diet composition: a protective effect?
Prior LJ, Velkoska E, Watts R, Cameron-Smith D, Morris MJ
International journal of obesity (2005)32(10)1585-94(2008 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

mitochondrial energy metabolism regulation by phosphorylation of COXIV-1 is coupled with prevention of COX allosteric inhibition by ATP
Title: Protein phosphorylation and prevention of cytochrome oxidase inhibition by ATP: coupled mechanisms of energy metabolism regulation.

The following Cox4i2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cox4i2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12459	NM_053472.1 Latest version!	Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa12459	XM_006235280.3 Latest version!	Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa12459	XM_017592080.1 Latest version!	Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa60556	XM_017592078.1 Latest version!	Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
ORa60557	XM_017592079.1 Latest version!	Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cox4i2 ( NM_053472.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445924.1 Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), mRNA.

Price & Availability↑

CloneID	ORa12459
Clone ID Related Accession (Same CDS sequence)	NM_053472.1 , XM_006235280.3 , XM_017592080.1
Accession Version	NM_053472.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF255347.1. ##Evidence-Data-START## Transcript exon combination :: AF255347.1, FM069824.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGTTTTCCA GAGCTACCCG GAGTCTGGTA ATGAAGACAG GAGGACTCAG AACTCAAGGG 
ACACACAGCC CAGGAAGTGC TGCTAGCAGC AGCCAGCGGA GGATGACCCC CTATGTTGAC 
TGCTATGCTC AGCGCTCCTA TCCCATGCCG GATGAGCCTT ACTGCACAGA GCTCAGCGAG 
GAGCAGCGGG CCCTGAAGGA GAAAGAGAAG GGCAGCTGGG CTCAGCTGAG CCAAGCAGAG 
AAGGTGGCCT TGTACCGGCT CCAGTTCCAC GAGACCTTCG CAGAGATGAA CCATCGCTCC 
AACGAATGGA AGACAGTAAT GGGCTGCGTC TTCTTCTTCA TTGGATTCAC GGCTCTGGTG 
ATTTGGTGGC AGCGGGTCTA TGTGTTCCCT AAGAAGGTTG TCACCCTGAC GGAAGAACGG 
AAAGCCCAGC AGCTCCAGCG CCTCCTGGAC ATGAAGAGCA ACCCCATACA GGGCCTGTCT 
GCCCACTGGG ATTACGAGAA GAAAGAGTGG AAAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445924.1
CDS	23..541
Translation	MFSRATRSLVMKTGGLRTQGTHSPGSAASSSQRRMTPYVDCYAQRSYPMPDEPYCTELSEEQRALKEKEKGSWAQLSQAEKVALYRLQFHETFAEMNHRSNEWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLSAHWDYEKKEWKK

Target ORF information:

RefSeq Version	NM_053472.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053472.1

ORF Insert Sequence:

ATGTTTTCCA GAGCTACCCG GAGTCTGGTA ATGAAGACAG GAGGACTCAG AACTCAAGGG 
ACACACAGCC CAGGAAGTGC TGCTAGCAGC AGCCAGCGGA GGATGACCCC CTATGTTGAC 
TGCTATGCTC AGCGCTCCTA TCCCATGCCG GATGAGCCTT ACTGCACAGA GCTCAGCGAG 
GAGCAGCGGG CCCTGAAGGA GAAAGAGAAG GGCAGCTGGG CTCAGCTGAG CCAAGCAGAG 
AAGGTGGCCT TGTACCGGCT CCAGTTCCAC GAGACCTTCG CAGAGATGAA CCATCGCTCC 
AACGAATGGA AGACAGTAAT GGGCTGCGTC TTCTTCTTCA TTGGATTCAC GGCTCTGGTG 
ATTTGGTGGC AGCGGGTCTA TGTGTTCCCT AAGAAGGTTG TCACCCTGAC GGAAGAACGG 
AAAGCCCAGC AGCTCCAGCG CCTCCTGGAC ATGAAGAGCA ACCCCATACA GGGCCTGTCT 
GCCCACTGGG ATTACGAGAA GAAAGAGTGG AAAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cox4i2 ( XM_006235280.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006235342.1 Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa12459
Clone ID Related Accession (Same CDS sequence)	NM_053472.1 , XM_006235280.3 , XM_017592080.1
Accession Version	XM_006235280.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006235280.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTTCCA GAGCTACCCG GAGTCTGGTA ATGAAGACAG GAGGACTCAG AACTCAAGGG 
ACACACAGCC CAGGAAGTGC TGCTAGCAGC AGCCAGCGGA GGATGACCCC CTATGTTGAC 
TGCTATGCTC AGCGCTCCTA TCCCATGCCG GATGAGCCTT ACTGCACAGA GCTCAGCGAG 
GAGCAGCGGG CCCTGAAGGA GAAAGAGAAG GGCAGCTGGG CTCAGCTGAG CCAAGCAGAG 
AAGGTGGCCT TGTACCGGCT CCAGTTCCAC GAGACCTTCG CAGAGATGAA CCATCGCTCC 
AACGAATGGA AGACAGTAAT GGGCTGCGTC TTCTTCTTCA TTGGATTCAC GGCTCTGGTG 
ATTTGGTGGC AGCGGGTCTA TGTGTTCCCT AAGAAGGTTG TCACCCTGAC GGAAGAACGG 
AAAGCCCAGC AGCTCCAGCG CCTCCTGGAC ATGAAGAGCA ACCCCATACA GGGCCTGTCT 
GCCCACTGGG ATTACGAGAA GAAAGAGTGG AAAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006235342.1
CDS	141..659
Translation	MFSRATRSLVMKTGGLRTQGTHSPGSAASSSQRRMTPYVDCYAQRSYPMPDEPYCTELSEEQRALKEKEKGSWAQLSQAEKVALYRLQFHETFAEMNHRSNEWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLSAHWDYEKKEWKK

Target ORF information:

RefSeq Version	XM_006235280.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006235280.3

ORF Insert Sequence:

ATGTTTTCCA GAGCTACCCG GAGTCTGGTA ATGAAGACAG GAGGACTCAG AACTCAAGGG 
ACACACAGCC CAGGAAGTGC TGCTAGCAGC AGCCAGCGGA GGATGACCCC CTATGTTGAC 
TGCTATGCTC AGCGCTCCTA TCCCATGCCG GATGAGCCTT ACTGCACAGA GCTCAGCGAG 
GAGCAGCGGG CCCTGAAGGA GAAAGAGAAG GGCAGCTGGG CTCAGCTGAG CCAAGCAGAG 
AAGGTGGCCT TGTACCGGCT CCAGTTCCAC GAGACCTTCG CAGAGATGAA CCATCGCTCC 
AACGAATGGA AGACAGTAAT GGGCTGCGTC TTCTTCTTCA TTGGATTCAC GGCTCTGGTG 
ATTTGGTGGC AGCGGGTCTA TGTGTTCCCT AAGAAGGTTG TCACCCTGAC GGAAGAACGG 
AAAGCCCAGC AGCTCCAGCG CCTCCTGGAC ATGAAGAGCA ACCCCATACA GGGCCTGTCT 
GCCCACTGGG ATTACGAGAA GAAAGAGTGG AAAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cox4i2 ( XM_017592080.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447569.1 Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa12459
Clone ID Related Accession (Same CDS sequence)	NM_053472.1 , XM_006235280.3 , XM_017592080.1
Accession Version	XM_017592080.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTTCCA GAGCTACCCG GAGTCTGGTA ATGAAGACAG GAGGACTCAG AACTCAAGGG 
ACACACAGCC CAGGAAGTGC TGCTAGCAGC AGCCAGCGGA GGATGACCCC CTATGTTGAC 
TGCTATGCTC AGCGCTCCTA TCCCATGCCG GATGAGCCTT ACTGCACAGA GCTCAGCGAG 
GAGCAGCGGG CCCTGAAGGA GAAAGAGAAG GGCAGCTGGG CTCAGCTGAG CCAAGCAGAG 
AAGGTGGCCT TGTACCGGCT CCAGTTCCAC GAGACCTTCG CAGAGATGAA CCATCGCTCC 
AACGAATGGA AGACAGTAAT GGGCTGCGTC TTCTTCTTCA TTGGATTCAC GGCTCTGGTG 
ATTTGGTGGC AGCGGGTCTA TGTGTTCCCT AAGAAGGTTG TCACCCTGAC GGAAGAACGG 
AAAGCCCAGC AGCTCCAGCG CCTCCTGGAC ATGAAGAGCA ACCCCATACA GGGCCTGTCT 
GCCCACTGGG ATTACGAGAA GAAAGAGTGG AAAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447569.1
CDS	90..608
Translation	MFSRATRSLVMKTGGLRTQGTHSPGSAASSSQRRMTPYVDCYAQRSYPMPDEPYCTELSEEQRALKEKEKGSWAQLSQAEKVALYRLQFHETFAEMNHRSNEWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLSAHWDYEKKEWKK

Target ORF information:

RefSeq Version	XM_017592080.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592080.1

ORF Insert Sequence:

ATGTTTTCCA GAGCTACCCG GAGTCTGGTA ATGAAGACAG GAGGACTCAG AACTCAAGGG 
ACACACAGCC CAGGAAGTGC TGCTAGCAGC AGCCAGCGGA GGATGACCCC CTATGTTGAC 
TGCTATGCTC AGCGCTCCTA TCCCATGCCG GATGAGCCTT ACTGCACAGA GCTCAGCGAG 
GAGCAGCGGG CCCTGAAGGA GAAAGAGAAG GGCAGCTGGG CTCAGCTGAG CCAAGCAGAG 
AAGGTGGCCT TGTACCGGCT CCAGTTCCAC GAGACCTTCG CAGAGATGAA CCATCGCTCC 
AACGAATGGA AGACAGTAAT GGGCTGCGTC TTCTTCTTCA TTGGATTCAC GGCTCTGGTG 
ATTTGGTGGC AGCGGGTCTA TGTGTTCCCT AAGAAGGTTG TCACCCTGAC GGAAGAACGG 
AAAGCCCAGC AGCTCCAGCG CCTCCTGGAC ATGAAGAGCA ACCCCATACA GGGCCTGTCT 
GCCCACTGGG ATTACGAGAA GAAAGAGTGG AAAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cox4i2 ( XM_017592078.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447567.1 Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa60556
Clone ID Related Accession (Same CDS sequence)	XM_017592078.1
Accession Version	XM_017592078.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 708bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGGTC CTAGTCCCGG GCATCGTCCC CGGCCCCAGA AATGGGGCCT CTTTCTAGAG 
GGTGGGGTGG CCCTTTTCCT AGAAATGCTG CCTCTCCCAC CCGCTGACCC AGTTTGGTCC 
TTGGCCTCTA AAGCCCCTGG GATGTCAGAC TCTGCACGTC CCGCGTCCCG TTCCGAGTCC 
GGAGTGATGA TGTTTTCCAG AGCTACCCGG AGTCTGGTAA TGAAGACAGG AGGACTCAGA 
ACTCAAGGGA CACACAGCCC AGGAAGTGCT GCTAGCAGCA GCCAGCGGAG GATGACCCCC 
TATGTTGACT GCTATGCTCA GCGCTCCTAT CCCATGCCGG ATGAGCCTTA CTGCACAGAG 
CTCAGCGAGG AGCAGCGGGC CCTGAAGGAG AAAGAGAAGG GCAGCTGGGC TCAGCTGAGC 
CAAGCAGAGA AGGTGGCCTT GTACCGGCTC CAGTTCCACG AGACCTTCGC AGAGATGAAC 
CATCGCTCCA ACGAATGGAA GACAGTAATG GGCTGCGTCT TCTTCTTCAT TGGATTCACG 
GCTCTGGTGA TTTGGTGGCA GCGGGTCTAT GTGTTCCCTA AGAAGGTTGT CACCCTGACG 
GAAGAACGGA AAGCCCAGCA GCTCCAGCGC CTCCTGGACA TGAAGAGCAA CCCCATACAG 
GGCCTGTCTG CCCACTGGGA TTACGAGAAG AAAGAGTGGA AAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447567.1
CDS	58..765
Translation	MLGPSPGHRPRPQKWGLFLEGGVALFLEMLPLPPADPVWSLASKAPGMSDSARPASRSESGVMMFSRATRSLVMKTGGLRTQGTHSPGSAASSSQRRMTPYVDCYAQRSYPMPDEPYCTELSEEQRALKEKEKGSWAQLSQAEKVALYRLQFHETFAEMNHRSNEWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLSAHWDYEKKEWKK

Target ORF information:

RefSeq Version	XM_017592078.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592078.1

ORF Insert Sequence:

ATGCTGGGTC CTAGTCCCGG GCATCGTCCC CGGCCCCAGA AATGGGGCCT CTTTCTAGAG 
GGTGGGGTGG CCCTTTTCCT AGAAATGCTG CCTCTCCCAC CCGCTGACCC AGTTTGGTCC 
TTGGCCTCTA AAGCCCCTGG GATGTCAGAC TCTGCACGTC CCGCGTCCCG TTCCGAGTCC 
GGAGTGATGA TGTTTTCCAG AGCTACCCGG AGTCTGGTAA TGAAGACAGG AGGACTCAGA 
ACTCAAGGGA CACACAGCCC AGGAAGTGCT GCTAGCAGCA GCCAGCGGAG GATGACCCCC 
TATGTTGACT GCTATGCTCA GCGCTCCTAT CCCATGCCGG ATGAGCCTTA CTGCACAGAG 
CTCAGCGAGG AGCAGCGGGC CCTGAAGGAG AAAGAGAAGG GCAGCTGGGC TCAGCTGAGC 
CAAGCAGAGA AGGTGGCCTT GTACCGGCTC CAGTTCCACG AGACCTTCGC AGAGATGAAC 
CATCGCTCCA ACGAATGGAA GACAGTAATG GGCTGCGTCT TCTTCTTCAT TGGATTCACG 
GCTCTGGTGA TTTGGTGGCA GCGGGTCTAT GTGTTCCCTA AGAAGGTTGT CACCCTGACG 
GAAGAACGGA AAGCCCAGCA GCTCCAGCGC CTCCTGGACA TGAAGAGCAA CCCCATACAG 
GGCCTGTCTG CCCACTGGGA TTACGAGAAG AAAGAGTGGA AAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cox4i2 ( XM_017592079.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447568.1 Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa60557
Clone ID Related Accession (Same CDS sequence)	XM_017592079.1
Accession Version	XM_017592079.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 702bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGGCT GGCATCAGAG AACGGGGCTC CCTGTCCTAA ACTGTTCAGA TCTCACCCAG 
TGGCTAGACC TCTTCCCACT TCTCAAACGA CGAATGAAAA CCCAAAGGTC CAGGGCAGCG 
GTTCTCAACC TGGGAGTTGA ACGACTCTTT TACAGGGGTC TCCTAAAACC ACTGGCGTAT 
CGGATGTTTT CCAGAGCTAC CCGGAGTCTG GTAATGAAGA CAGGAGGACT CAGAACTCAA 
GGGACACACA GCCCAGGAAG TGCTGCTAGC AGCAGCCAGC GGAGGATGAC CCCCTATGTT 
GACTGCTATG CTCAGCGCTC CTATCCCATG CCGGATGAGC CTTACTGCAC AGAGCTCAGC 
GAGGAGCAGC GGGCCCTGAA GGAGAAAGAG AAGGGCAGCT GGGCTCAGCT GAGCCAAGCA 
GAGAAGGTGG CCTTGTACCG GCTCCAGTTC CACGAGACCT TCGCAGAGAT GAACCATCGC 
TCCAACGAAT GGAAGACAGT AATGGGCTGC GTCTTCTTCT TCATTGGATT CACGGCTCTG 
GTGATTTGGT GGCAGCGGGT CTATGTGTTC CCTAAGAAGG TTGTCACCCT GACGGAAGAA 
CGGAAAGCCC AGCAGCTCCA GCGCCTCCTG GACATGAAGA GCAACCCCAT ACAGGGCCTG 
TCTGCCCACT GGGATTACGA GAAGAAAGAG TGGAAAAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447568.1
CDS	38..739
Translation	MGGWHQRTGLPVLNCSDLTQWLDLFPLLKRRMKTQRSRAAVLNLGVERLFYRGLLKPLAYRMFSRATRSLVMKTGGLRTQGTHSPGSAASSSQRRMTPYVDCYAQRSYPMPDEPYCTELSEEQRALKEKEKGSWAQLSQAEKVALYRLQFHETFAEMNHRSNEWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLSAHWDYEKKEWKK

Target ORF information:

RefSeq Version	XM_017592079.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cytochrome c oxidase subunit 4i2 (Cox4i2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592079.1

ORF Insert Sequence:

ATGGGAGGCT GGCATCAGAG AACGGGGCTC CCTGTCCTAA ACTGTTCAGA TCTCACCCAG 
TGGCTAGACC TCTTCCCACT TCTCAAACGA CGAATGAAAA CCCAAAGGTC CAGGGCAGCG 
GTTCTCAACC TGGGAGTTGA ACGACTCTTT TACAGGGGTC TCCTAAAACC ACTGGCGTAT 
CGGATGTTTT CCAGAGCTAC CCGGAGTCTG GTAATGAAGA CAGGAGGACT CAGAACTCAA 
GGGACACACA GCCCAGGAAG TGCTGCTAGC AGCAGCCAGC GGAGGATGAC CCCCTATGTT 
GACTGCTATG CTCAGCGCTC CTATCCCATG CCGGATGAGC CTTACTGCAC AGAGCTCAGC 
GAGGAGCAGC GGGCCCTGAA GGAGAAAGAG AAGGGCAGCT GGGCTCAGCT GAGCCAAGCA 
GAGAAGGTGG CCTTGTACCG GCTCCAGTTC CACGAGACCT TCGCAGAGAT GAACCATCGC 
TCCAACGAAT GGAAGACAGT AATGGGCTGC GTCTTCTTCT TCATTGGATT CACGGCTCTG 
GTGATTTGGT GGCAGCGGGT CTATGTGTTC CCTAAGAAGG TTGTCACCCT GACGGAAGAA 
CGGAAAGCCC AGCAGCTCCA GCGCCTCCTG GACATGAAGA GCAACCCCAT ACAGGGCCTG 
TCTGCCCACT GGGATTACGA GAAGAAAGAG TGGAAAAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2.
Nucleic acids research41(4)2255-66(2013 Feb)
Aras S,Pak O,Sommer N,Finley R Jr,H?ttemann M,Weissmann N,Grossman LI

Protein phosphorylation and prevention of cytochrome oxidase inhibition by ATP: coupled mechanisms of energy metabolism regulation.
Cell metabolism13(6)712-9(2011 Jun)
Acin-Perez R,Gatti DL,Bai Y,Manfredi G

Exocrine pancreatic insufficiency, dyserythropoeitic anemia, and calvarial hyperostosis are caused by a mutation in the COX4I2 gene.
American journal of human genetics84(3)412-7(2009 Mar)
Shteyer E,Saada A,Shaag A,Al-Hijawi FA,Kidess R,Revel-Vilk S,Elpeleg O

Undernutrition during suckling in rats elevates plasma adiponectin and its receptor in skeletal muscle regardless of diet composition: a protective effect?
International journal of obesity (2005)32(10)1585-94(2008 Oct)
Prior LJ,Velkoska E,Watts R,Cameron-Smith D,Morris MJ