The following Gab2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gab2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa09494 | |
| Clone ID Related Accession (Same CDS sequence) | NM_053417.1 | |
| Accession Version | NM_053417.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1998bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | GRB2-associated-binding protein 2 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF230367.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF230367.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAGCGGCG GCGGCGGCGA CGACGTGGTG TGTACCGGCT GGCTGAGGAA ATCGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_445869.1 |
| CDS | 1..1998 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_053417.1 |
1 | ATGAGCGGCG GCGGCGGCGA CGACGTGGTG TGTACCGGCT GGCTGAGGAA ATCGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa56875 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017589791.1 | |
| Accession Version | XM_017589791.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1995bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | GRB2-associated-binding protein 2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAGCGGCG GCGGCGACGA CGTGGTGTGT ACCGGCTGGC TGAGGAAATC GCCTCCGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017445280.1 |
| CDS | 163..2157 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017589791.1 |
1 | ATGAGCGGCG GCGGCGACGA CGTGGTGTGT ACCGGCTGGC TGAGGAAATC GCCTCCGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility. |
Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors. |
PKA and GAB2 play central roles in the FSH signaling pathway to PI3K and AKT in ovarian granulosa cells. |
Inhibition of the antigen-induced activation of RBL-2H3 cells by Gab2 siRNA. |
Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein. |
