Gmeb2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gmeb2
Entrez Gene ID	83635
Full Name	glucocorticoid modulatory element binding protein 2
General protein information	Preferred Names glucocorticoid modulatory element binding protein 2 Names glucocorticoid modulatory element-binding protein 2 GMEB-2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q43
Summary	modulates transactivation by the glucocorticoid receptor and initiation of parvovirus replication; may play important roles in development and differentiation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031803.1	NP_113991.1	glucocorticoid modulatory element-binding protein 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Gmeb2	NP_937812.1
Gallus gallus (chicken)	GMEB2	XP_417437.3
Homo sapiens (human)	GMEB2	NP_036516.1
Pan troglodytes (chimpanzee)	GMEB2	XP_530318.3
Rattus norvegicus (Norway rat)	Gmeb2	NP_113991.1
Danio rerio (zebrafish)	si:ch73-302a13.2	XP_003201283.1
Canis lupus familiaris (dog)	GMEB2	XP_005635350.1
Bos taurus (cattle)	GMEB2	NP_001179105.1
Danio rerio (zebrafish)	LOC100536435	XP_003201284.1

Gene Ontology
Bibliography

Related articles in PubMed

Structure/activity relationships for GMEB-2: the second member of the glucocorticoid modulatory element-binding complex.
Chen J, He Y, Simons SS Jr
Biochemistry43(1)245-55(2004 Jan)

Properties of the glucocorticoid modulatory element binding proteins GMEB-1 and -2: potential new modifiers of glucocorticoid receptor transactivation and members of the family of KDWK proteins.
Kaul S, Blackford JA Jr, Chen J, Ogryzko VV, Simons SS Jr
Molecular endocrinology (Baltimore, Md.)14(7)1010-27(2000 Jul)

Genomic organization of human GMEB-1 and rat GMEB-2: structural conservation of two multifunctional proteins.
Zeng H, Kaul S, Simons SS Jr
Nucleic acids research28(8)1819-29(2000 Apr)

Cloning and characterization of a novel binding factor (GMEB-2) of the glucocorticoid modulatory element.
Zeng H, Jackson DA, Oshima H, Simons SS Jr
The Journal of biological chemistry273(28)17756-62(1998 Jul)

The factor binding to the glucocorticoid modulatory element of the tyrosine aminotransferase gene is a novel and ubiquitous heteromeric complex.
Oshima H, Szapary D, Simons SS Jr
The Journal of biological chemistry270(37)21893-901(1995 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gmeb2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gmeb2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08771	NM_031803.1 Latest version!	Rattus norvegicus glucocorticoid modulatory element binding protein 2 (Gmeb2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$314.30 $449.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gmeb2 ( NM_031803.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113991.1 Rattus norvegicus glucocorticoid modulatory element binding protein 2 (Gmeb2), mRNA.

Price & Availability↑

CloneID	ORa08771
Clone ID Related Accession (Same CDS sequence)	NM_031803.1
Accession Version	NM_031803.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1590bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	glucocorticoid modulatory element-binding protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF059273.1. ##Evidence-Data-START## Transcript exon combination :: AF059273.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCAACTC CAGATGTCAG CGTCCACATG GAAGAAGTAG TGGTTGTGAC AACTCCAGAC 
ACTGCAGTTG ATGGCAGTGG TGTAGAGGAG GTGAAGACAG TGCTTGTGAC AACGAACCTA 
GCTCCTCATG GGGGTGATTT GACAGAAGAT AACATGGAAA CAGAAAATGC AGCAGCTGCA 
GCCTGTGCCT TTACAGCCTC CTCACAGCTC AAGGAAGCCG TGTTAGTGAA GATGGCTGAA 
GAGGGGGAGA ACTTAGAGGC TGAAATTGTG TACCCCATCA CTTGTGGAGA CAGCAGAGCT 
AACCTCATCT GGAGGAAGTT TGTGTGCCCT GGAATCAATG TGAAATGTGT TCAGTACGAT 
GAACATGTGA TCAGCCCAAA GGAGTTTGTG CATCTGGCAG GGAAGTCTAC CCTGAAGGAC 
TGGAAGAGAG CCATCCGGAT GAACGGCATC ATGCTCAGGA AGATCATGGA CTCTGGGGAG 
CTAGACTTCT ACCAGCATGA CAAGGTCTGC TCTAATACTT GCCGAAGCAC CAAGATTGAC 
CTCTCAGGGG CCCGTGTGTC CCTGAGCAGT CCAACATCCA CAGAGTACAT CCCGCTCACA 
CCAGCTGCAG CTGATGTGAA TGGCTCACCT GCCACCATCA CCATAGAGAC CTGTGAGGAC 
CCTGGTGACT GGACCACAAC CATTGGAGAC GACACATTTG CATTCTGGCG GGGACTGAAG 
GATGCGGGCT TACTGGATGA AGTCATACAG GAATTTCAAC AGGAGCTGGA GGAAACCATG 
AAAGGCCTGC AGCAGCGAGT GCAGGACCCG CCCCTACAGC TCCGAGATGC TGTCCTCCTC 
AATAACATCG TGCAAAACTT TGGCATGCTG GATCTGGTAA AGAAGGTACT GGCCAGCCAC 
AAGTGCCAGA TGGATCGTTC TCGAGAACAG TATGCACGGG ACCTGGCAGC CCTGGAACAG 
CAGTGTGATG AACATCGCCG CCGTGCCAAG GAACTGAAGC ACAAGTCCCA GCACCTTAGC 
AATGTGCTCA TGACGTTGAC CCCAGTTTCC CTGCCATCCC CTATGAAGCG GCCCCGTCTT 
GCACGGGCTA CATCTGGACC AGCTGCTATG GCTTCCCAGG TGCTTACACA GTCTGCACAG 
ATTGCACTTG GCCCAGGAAT GCCTATGTCC CAGTTGACCA GTGTGCCACT TGGCAAAGTA 
GTATCTACAC TGCCCTCCAC TGTCCTGGGC AAGGGCTCTC CTCAAGCTGC CCCAGCCAGT 
TCACCGGCCT CCCCACTGCT TGGAGGCTAC ACAGTTTTGG CCTCCTCTGG CTCTACCTTC 
CCCAGCACAG TAGAGATTCA TCCGGACACA TCCAGCCTCA CAGTTTTGAG CACAGCTGCC 
ATGCAGGATG GCACGACAGT ACTAAAGGTG GTCAGCCCCC TGCAGCTGCT CACCCTGCCT 
GGCCTGGGAC CCACACTACA GAATGTGGCT CAGGCATCAC CTGCAGGCAG CACCATTGTG 
ACAATGCCTA CAGCAGCTGC TACTGGACCT GAGGAACACA CAGCCACTAT TGAGGTGGCC 
GCTGTAGCAG AGGACCATGA GCAGAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113991.1
CDS	110..1699
Translation	MATPDVSVHMEEVVVVTTPDTAVDGSGVEEVKTVLVTTNLAPHGGDLTEDNMETENAAAAACAFTASSQLKEAVLVKMAEEGENLEAEIVYPITCGDSRANLIWRKFVCPGINVKCVQYDEHVISPKEFVHLAGKSTLKDWKRAIRMNGIMLRKIMDSGELDFYQHDKVCSNTCRSTKIDLSGARVSLSSPTSTEYIPLTPAAADVNGSPATITIETCEDPGDWTTTIGDDTFAFWRGLKDAGLLDEVIQEFQQELEETMKGLQQRVQDPPLQLRDAVLLNNIVQNFGMLDLVKKVLASHKCQMDRSREQYARDLAALEQQCDEHRRRAKELKHKSQHLSNVLMTLTPVSLPSPMKRPRLARATSGPAAMASQVLTQSAQIALGPGMPMSQLTSVPLGKVVSTLPSTVLGKGSPQAAPASSPASPLLGGYTVLASSGSTFPSTVEIHPDTSSLTVLSTAAMQDGTTVLKVVSPLQLLTLPGLGPTLQNVAQASPAGSTIVTMPTAAATGPEEHTATIEVAAVAEDHEQK

Target ORF information:

RefSeq Version	NM_031803.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glucocorticoid modulatory element binding protein 2 (Gmeb2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031803.1

ORF Insert Sequence:

ATGGCAACTC CAGATGTCAG CGTCCACATG GAAGAAGTAG TGGTTGTGAC AACTCCAGAC 
ACTGCAGTTG ATGGCAGTGG TGTAGAGGAG GTGAAGACAG TGCTTGTGAC AACGAACCTA 
GCTCCTCATG GGGGTGATTT GACAGAAGAT AACATGGAAA CAGAAAATGC AGCAGCTGCA 
GCCTGTGCCT TTACAGCCTC CTCACAGCTC AAGGAAGCCG TGTTAGTGAA GATGGCTGAA 
GAGGGGGAGA ACTTAGAGGC TGAAATTGTG TACCCCATCA CTTGTGGAGA CAGCAGAGCT 
AACCTCATCT GGAGGAAGTT TGTGTGCCCT GGAATCAATG TGAAATGTGT TCAGTACGAT 
GAACATGTGA TCAGCCCAAA GGAGTTTGTG CATCTGGCAG GGAAGTCTAC CCTGAAGGAC 
TGGAAGAGAG CCATCCGGAT GAACGGCATC ATGCTCAGGA AGATCATGGA CTCTGGGGAG 
CTAGACTTCT ACCAGCATGA CAAGGTCTGC TCTAATACTT GCCGAAGCAC CAAGATTGAC 
CTCTCAGGGG CCCGTGTGTC CCTGAGCAGT CCAACATCCA CAGAGTACAT CCCGCTCACA 
CCAGCTGCAG CTGATGTGAA TGGCTCACCT GCCACCATCA CCATAGAGAC CTGTGAGGAC 
CCTGGTGACT GGACCACAAC CATTGGAGAC GACACATTTG CATTCTGGCG GGGACTGAAG 
GATGCGGGCT TACTGGATGA AGTCATACAG GAATTTCAAC AGGAGCTGGA GGAAACCATG 
AAAGGCCTGC AGCAGCGAGT GCAGGACCCG CCCCTACAGC TCCGAGATGC TGTCCTCCTC 
AATAACATCG TGCAAAACTT TGGCATGCTG GATCTGGTAA AGAAGGTACT GGCCAGCCAC 
AAGTGCCAGA TGGATCGTTC TCGAGAACAG TATGCACGGG ACCTGGCAGC CCTGGAACAG 
CAGTGTGATG AACATCGCCG CCGTGCCAAG GAACTGAAGC ACAAGTCCCA GCACCTTAGC 
AATGTGCTCA TGACGTTGAC CCCAGTTTCC CTGCCATCCC CTATGAAGCG GCCCCGTCTT 
GCACGGGCTA CATCTGGACC AGCTGCTATG GCTTCCCAGG TGCTTACACA GTCTGCACAG 
ATTGCACTTG GCCCAGGAAT GCCTATGTCC CAGTTGACCA GTGTGCCACT TGGCAAAGTA 
GTATCTACAC TGCCCTCCAC TGTCCTGGGC AAGGGCTCTC CTCAAGCTGC CCCAGCCAGT 
TCACCGGCCT CCCCACTGCT TGGAGGCTAC ACAGTTTTGG CCTCCTCTGG CTCTACCTTC 
CCCAGCACAG TAGAGATTCA TCCGGACACA TCCAGCCTCA CAGTTTTGAG CACAGCTGCC 
ATGCAGGATG GCACGACAGT ACTAAAGGTG GTCAGCCCCC TGCAGCTGCT CACCCTGCCT 
GGCCTGGGAC CCACACTACA GAATGTGGCT CAGGCATCAC CTGCAGGCAG CACCATTGTG 
ACAATGCCTA CAGCAGCTGC TACTGGACCT GAGGAACACA CAGCCACTAT TGAGGTGGCC 
GCTGTAGCAG AGGACCATGA GCAGAAGTAG