Slc27a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc27a2
Entrez Gene ID	65192
Full Name	solute carrier family 27 member 2
General protein information	Preferred Names solute carrier family 27 member 2 Names very long-chain acyl-CoA synthetase FATP-2 THCA-CoA ligase VLACS VLCS fatty acid transport protein 2 fatty-acid-coenzyme A ligase, very long-chain 1 long-chain-fatty-acid--CoA ligase solute carrier family 27 (fatty acid transporter), member 2 solute carrier family 27 (fatty acid transporter), member 32 very long-chain-fatty-acid-CoA ligase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q36
Summary	has very long-chain acyl-CoA synthetase activity; may play a role in fatty acid metabolism [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031736.1	NP_113924.1	very long-chain acyl-CoA synthetase

Pathways from BioSystems

Homologies

Homo sapiens (human)	SLC27A2	NP_003636.2
	SLC27A2	XP_001114121.1
Canis lupus familiaris (dog)	SLC27A2	XP_535473.2
Rattus norvegicus (Norway rat)	Slc27a2	NP_113924.1
Magnaporthe oryzae (rice blast fungus)	MGG_05025	XP_003712531.1
Bos taurus (cattle)	SLC27A2	NP_001179792.1
Danio rerio (zebrafish)	slc27a2b	XP_001336957.1
Xenopus tropicalis (tropical clawed frog)	LOC100494612	XP_002938916.1
Pan troglodytes (chimpanzee)	SLC27A2	XP_510394.2
Mus musculus (house mouse)	Slc27a2	NP_036108.2
Gallus gallus (chicken)	SLC27A2	XP_424010.3
Danio rerio (zebrafish)	zgc:101540	NP_001008639.1

Gene Ontology
Bibliography

Related articles in PubMed

Kidney Proximal Tubule Lipoapoptosis Is Regulated by Fatty Acid Transporter-2 (FATP2).
Khan S, Cabral PD, Schilling WP, Schmidt ZW, Uddin AN, Gingras A, Madhavan SM, Garvin JL, Schelling JR
Journal of the American Society of Nephrology : JASN29(1)81-91(2018 Jan)

Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway.
Ohkuni A, Ohno Y, Kihara A
Biochemical and biophysical research communications442(3-4)195-201(2013 Dec)

Human fatty acid transport protein 2a/very long chain acyl-CoA synthetase 1 (FATP2a/Acsvl1) has a preference in mediating the channeling of exogenous n-3 fatty acids into phosphatidylinositol.
Melton EM, Cerny RL, Watkins PA, DiRusso CC, Black PN
The Journal of biological chemistry286(35)30670-9(2011 Sep)

Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells.
Krammer J, Digel M, Ehehalt F, Stremmel W, F?llekrug J, Ehehalt R
International journal of medical sciences8(7)599-614(2011)

FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase.
Falcon A, Doege H, Fluitt A, Tsang B, Watson N, Kay MA, Stahl A
American journal of physiology. Endocrinology and metabolism299(3)E384-93(2010 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The progressive overexpression of slc27a2 in peripheral blood mononuclear cells of cafeteria-fed rats as the body weight increases suggests this gene as an early marker of overweight development related to the intake of a hyperlipidic diet.
Title: Slc27a2 expression in peripheral blood mononuclear cells as a molecular marker for overweight development.

In response to an increase of cellular cholesterol, fatty acid transporter is translocated from cytosol to membranes of type II pneumocytes.
Title: Cellular cholesterol stimulates acute uptake of palmitate by redistribution of fatty acid translocase in type II pneumocytes.

The following Slc27a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc27a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42712	NM_031736.1 Latest version!	Rattus norvegicus solute carrier family 27 member 2 (Slc27a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc27a2 ( NM_031736.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113924.1 Rattus norvegicus solute carrier family 27 member 2 (Slc27a2), mRNA.

Price & Availability↑

CloneID	ORa42712
Clone ID Related Accession (Same CDS sequence)	NM_031736.1
Accession Version	NM_031736.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1863bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Rattus norvegicus(Norway rat)
Product	very long-chain acyl-CoA synthetase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D85100.1. On Dec 17, 2003 this sequence version replaced XM_346669.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D85100.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689597, SAMEA2689598 [ECO:0000348] ##Evidence-Data-END##

ATGCTGCCTG TGCTCTACAC CGGCCTGGCG GGGCTGCTGC TGCTGCCTCT GCTGCTCACC 
TGCTGCTGCC CCTACCTCCT CCAGGACGTG CGGTTCTTCC TGCAACTGGC CAACATGGCC 
CGGCAGGTGC GCAGCTACCG GCAGCGGCGA CCCGTGCGCA CCATCCTGCA TGTCTTCTTG 
GAGCAAGCGC GCAAGACCCC GCACAAGCCC TTCCTGCTGT TTCGCGACGA GACGCTTACC 
TACGCCCAGG TAGACCGGCG CAGCAACCAA GTAGCGCGAG CGCTGCATGA TCACCTGGGC 
CTGCGGCAGG GGGATTGCGT GGCCCTCTTC ATGGGCAATG AGCCGGCCTA CGTGTGGCTC 
TGGCTGGGAC TGCTCAAACT GGGCTGTCCC ATGGCGTGCC TCAACTACAA CATCCGTGCC 
AAGTCTCTGC TACACTGCTT TCAGTGCTGC GGGGCGAAGG TGCTGCTGGC CTCCCCAGAG 
CTACACGAAG CTGTCGAGGA GGTTCTTCCA ACCCTGAAAA AGGAGGGCGT GTCCGTCTTC 
TACGTAAGCA GAACTTCTAA CACTAATGGC GTGGACACAG TACTGGACAA AGTAGACGGG 
GTGTCGGCGG ACCCCATCCC GGAGTCGTGG AGGTCTGAAG TCACGTTCAC CACACCCGCA 
GTCTACATAT ATACTTCGGG CACCACAGGT CTTCCAAAGG CTGCAACCAT TAATCACCAT 
CGCCTCTGGT ATGGGACCAG CCTTGCCCTG AGGTCCGGAA TTAAGGCTCA TGACGTCATC 
TACACCACCA TGCCCCTGTA CCACAGCGCG GCGCTCATGA TTGGCCTCCA CGGATGCATT 
GTGGTTGGGG CTACATTTGC TTTGCGGAGC AAATTTTCAG CCAGCCAGTT TTGGGACGAC 
TGCAGGAAAT ACAACGCCAC TGTCATTCAG TACATCGGTG AACTGCTTCG GTACCTCTGC 
AACACGCCCC AGAAACCAAA TGACCGGGAC CACAAAGTGA AAATAGCACT AGGAAATGGC 
TTACGAGGAG ATGTGTGGAG AGAGTTCATC AAGAGATTTG GGGACATTCA CATTTATGAG 
TTCTACGCTT CCACTGAAGG CAACATTGGA TTTATGAACT ATCCAAGAAA AATCGGAGCT 
GTTGGAAGAG AAAATTACCT ACAAAAAAAA GTTGTAAGGC ACGAGCTGAT CAAGTATGAC 
GTGGAGAAGG ATGAGCCTGT CCGTGATGCA AATGGATATT GCATCAAAGT CCCCAAAGGA 
GAGGTTGGAC TCTTGATTTG CAAAATCACA GAGCTCACAC CATTTTTTGG CTATGCTGGA 
GGAAAGACCC AGACAGAGAA GAAAAAGCTC AGAGATGTTT TTAAGAAAGG AGACGTCTAC 
TTCAACAGTG GCGATCTCCT GATGATCGAC CGTGAAAATT TCATCTATTT TCACGACAGA 
GTTGGAGACA CCTTCCGGTG GAAAGGAGAG AATGTAGCTA CCACGGAAGT CGCTGACATT 
GTGGGACTGG TAGATTTTGT TGAAGAAGTG AATGTTTACG GTGTGCCCGT GCCAGGTCAT 
GAAGGTCGCA TCGGGATGGC CTCGATCAAG ATGAAAGAAA ACTACGAGTT CAATGGAAAG 
AAACTCTTTC AGCACATCTC GGAGTACCTG CCCAGTTACT CGAGGCCTCG GTTCCTGAGA 
ATACAAGATA CCATTGAGAT CACCGGGACT TTTAAACACC GCAAAGTGAC CCTGATGGAA 
GAGGGCTTTA ACCCCTCAGT CATCAAAGAT ACCTTGTATT TCATGGATGA CACAGAAAAA 
ACATACGTGC CCATGACTGA GGACATTTAT AATGCCATAA TTGATAAGAC TCTGAAGCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113924.1
CDS	795..2657
Translation	MLPVLYTGLAGLLLLPLLLTCCCPYLLQDVRFFLQLANMARQVRSYRQRRPVRTILHVFLEQARKTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALFMGNEPAYVWLWLGLLKLGCPMACLNYNIRAKSLLHCFQCCGAKVLLASPELHEAVEEVLPTLKKEGVSVFYVSRTSNTNGVDTVLDKVDGVSADPIPESWRSEVTFTTPAVYIYTSGTTGLPKAATINHHRLWYGTSLALRSGIKAHDVIYTTMPLYHSAALMIGLHGCIVVGATFALRSKFSASQFWDDCRKYNATVIQYIGELLRYLCNTPQKPNDRDHKVKIALGNGLRGDVWREFIKRFGDIHIYEFYASTEGNIGFMNYPRKIGAVGRENYLQKKVVRHELIKYDVEKDEPVRDANGYCIKVPKGEVGLLICKITELTPFFGYAGGKTQTEKKKLRDVFKKGDVYFNSGDLLMIDRENFIYFHDRVGDTFRWKGENVATTEVADIVGLVDFVEEVNVYGVPVPGHEGRIGMASIKMKENYEFNGKKLFQHISEYLPSYSRPRFLRIQDTIEITGTFKHRKVTLMEEGFNPSVIKDTLYFMDDTEKTYVPMTEDIYNAIIDKTLKL

Target ORF information:

RefSeq Version	NM_031736.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 27 member 2 (Slc27a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031736.1

ORF Insert Sequence:

ATGCTGCCTG TGCTCTACAC CGGCCTGGCG GGGCTGCTGC TGCTGCCTCT GCTGCTCACC 
TGCTGCTGCC CCTACCTCCT CCAGGACGTG CGGTTCTTCC TGCAACTGGC CAACATGGCC 
CGGCAGGTGC GCAGCTACCG GCAGCGGCGA CCCGTGCGCA CCATCCTGCA TGTCTTCTTG 
GAGCAAGCGC GCAAGACCCC GCACAAGCCC TTCCTGCTGT TTCGCGACGA GACGCTTACC 
TACGCCCAGG TAGACCGGCG CAGCAACCAA GTAGCGCGAG CGCTGCATGA TCACCTGGGC 
CTGCGGCAGG GGGATTGCGT GGCCCTCTTC ATGGGCAATG AGCCGGCCTA CGTGTGGCTC 
TGGCTGGGAC TGCTCAAACT GGGCTGTCCC ATGGCGTGCC TCAACTACAA CATCCGTGCC 
AAGTCTCTGC TACACTGCTT TCAGTGCTGC GGGGCGAAGG TGCTGCTGGC CTCCCCAGAG 
CTACACGAAG CTGTCGAGGA GGTTCTTCCA ACCCTGAAAA AGGAGGGCGT GTCCGTCTTC 
TACGTAAGCA GAACTTCTAA CACTAATGGC GTGGACACAG TACTGGACAA AGTAGACGGG 
GTGTCGGCGG ACCCCATCCC GGAGTCGTGG AGGTCTGAAG TCACGTTCAC CACACCCGCA 
GTCTACATAT ATACTTCGGG CACCACAGGT CTTCCAAAGG CTGCAACCAT TAATCACCAT 
CGCCTCTGGT ATGGGACCAG CCTTGCCCTG AGGTCCGGAA TTAAGGCTCA TGACGTCATC 
TACACCACCA TGCCCCTGTA CCACAGCGCG GCGCTCATGA TTGGCCTCCA CGGATGCATT 
GTGGTTGGGG CTACATTTGC TTTGCGGAGC AAATTTTCAG CCAGCCAGTT TTGGGACGAC 
TGCAGGAAAT ACAACGCCAC TGTCATTCAG TACATCGGTG AACTGCTTCG GTACCTCTGC 
AACACGCCCC AGAAACCAAA TGACCGGGAC CACAAAGTGA AAATAGCACT AGGAAATGGC 
TTACGAGGAG ATGTGTGGAG AGAGTTCATC AAGAGATTTG GGGACATTCA CATTTATGAG 
TTCTACGCTT CCACTGAAGG CAACATTGGA TTTATGAACT ATCCAAGAAA AATCGGAGCT 
GTTGGAAGAG AAAATTACCT ACAAAAAAAA GTTGTAAGGC ACGAGCTGAT CAAGTATGAC 
GTGGAGAAGG ATGAGCCTGT CCGTGATGCA AATGGATATT GCATCAAAGT CCCCAAAGGA 
GAGGTTGGAC TCTTGATTTG CAAAATCACA GAGCTCACAC CATTTTTTGG CTATGCTGGA 
GGAAAGACCC AGACAGAGAA GAAAAAGCTC AGAGATGTTT TTAAGAAAGG AGACGTCTAC 
TTCAACAGTG GCGATCTCCT GATGATCGAC CGTGAAAATT TCATCTATTT TCACGACAGA 
GTTGGAGACA CCTTCCGGTG GAAAGGAGAG AATGTAGCTA CCACGGAAGT CGCTGACATT 
GTGGGACTGG TAGATTTTGT TGAAGAAGTG AATGTTTACG GTGTGCCCGT GCCAGGTCAT 
GAAGGTCGCA TCGGGATGGC CTCGATCAAG ATGAAAGAAA ACTACGAGTT CAATGGAAAG 
AAACTCTTTC AGCACATCTC GGAGTACCTG CCCAGTTACT CGAGGCCTCG GTTCCTGAGA 
ATACAAGATA CCATTGAGAT CACCGGGACT TTTAAACACC GCAAAGTGAC CCTGATGGAA 
GAGGGCTTTA ACCCCTCAGT CATCAAAGAT ACCTTGTATT TCATGGATGA CACAGAAAAA 
ACATACGTGC CCATGACTGA GGACATTTAT AATGCCATAA TTGATAAGAC TCTGAAGCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Kidney Proximal Tubule Lipoapoptosis Is Regulated by Fatty Acid Transporter-2 (FATP2).
Journal of the American Society of Nephrology : JASN29(1)81-91(2018 Jan)
Khan S,Cabral PD,Schilling WP,Schmidt ZW,Uddin AN,Gingras A,Madhavan SM,Garvin JL,Schelling JR

Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway.
Biochemical and biophysical research communications442(3-4)195-201(2013 Dec)
Ohkuni A,Ohno Y,Kihara A

Human fatty acid transport protein 2a/very long chain acyl-CoA synthetase 1 (FATP2a/Acsvl1) has a preference in mediating the channeling of exogenous n-3 fatty acids into phosphatidylinositol.
The Journal of biological chemistry286(35)30670-9(2011 Sep)
Melton EM,Cerny RL,Watkins PA,DiRusso CC,Black PN

Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells.
International journal of medical sciences8(7)599-614(2011)
Krammer J,Digel M,Ehehalt F,Stremmel W,F?llekrug J,Ehehalt R

FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase.
American journal of physiology. Endocrinology and metabolism299(3)E384-93(2010 Sep)
Falcon A,Doege H,Fluitt A,Tsang B,Watson N,Kay MA,Stahl A

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Slc27a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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