Sh3bp4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sh3bp4
Entrez Gene ID	64634
Full Name	SH3-domain binding protein 4
General protein information	Preferred Names SH3-domain binding protein 4 Names SH3 domain-binding protein 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q35
Summary	human homolog may be involved in endocytosis, intracellular sorting, and the cell cycle [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022693.4	NP_073184.3	SH3 domain-binding protein 4
XM_008767298.2	XP_008765520.1	SH3 domain-binding protein 4 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Sh3bp4	NP_598577.1
Canis lupus familiaris (dog)	SH3BP4	XP_005635964.1
Homo sapiens (human)	SH3BP4	NP_055336.1
Bos taurus (cattle)	SH3BP4	NP_001137560.1
Rattus norvegicus (Norway rat)	Sh3bp4	NP_073184.3
Gallus gallus (chicken)	LOC100857104	XP_003641592.1
Xenopus tropicalis (tropical clawed frog)	sh3bp4	NP_001011179.1
	SH3BP4	XP_001082225.1
Gallus gallus (chicken)	SH3BP4	XP_004942557.1
Danio rerio (zebrafish)	sh3bp4a	NP_991316.1
Pan troglodytes (chimpanzee)	SH3BP4	XP_001152122.1

Gene Ontology
Bibliography

Related articles in PubMed

dRAGging amino acid-mTORC1 signaling by SH3BP4.
Kim YM, Kim DH
Molecules and cells35(1)1-6(2013 Jan)

SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.
Kim YM, Stone M, Hwang TH, Kim YG, Dunlevy JR, Griffin TJ, Kim DH
Molecular cell46(6)833-46(2012 Jun)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

TTP specifically regulates the internalization of the transferrin receptor.
Tosoni D, Puri C, Confalonieri S, Salcini AE, De Camilli P, Tacchetti C, Di Fiore PP
Cell123(5)875-88(2005 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SH3 binding protein 4 (SH3BP4) has been identified as a negative regulator of Rag GTPases under amino acid starvation. Rag GTPase heterodimers regulate the amino acid-mTORC1 pathway, a master regulator of cell growth and autophagy.
Title: dRAGging amino acid-mTORC1 signaling by SH3BP4.

The following Sh3bp4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sh3bp4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06268	NM_022693.4 Latest version!	Rattus norvegicus SH3-domain binding protein 4 (Sh3bp4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa06268	XM_008767298.2 Latest version!	Rattus norvegicus SH3-domain binding protein 4 (Sh3bp4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sh3bp4 ( NM_022693.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_073184.3 Rattus norvegicus SH3-domain binding protein 4 (Sh3bp4), mRNA.

Price & Availability↑

CloneID	ORa06268
Clone ID Related Accession (Same CDS sequence)	NM_022693.4 , XM_008767298.2
Accession Version	NM_022693.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2886bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Rattus norvegicus(Norway rat)
Product	SH3 domain-binding protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FM034920.1 and AABR07068289.1. On Mar 2, 2013 this sequence version replaced NM_022693.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## CDS exon combination :: AJ278266.2 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGCCC AGCGCATCCG GGCAGCCAAC TCCAGTGGCC TCCCTCGGTG CAAGTCGGAG 
GGGACTCTGA TCGACCTGAG CGAGGGCTTC TCAGAGACAA GCTTTAATGA TGTCAAAGTG 
CCTTCCCCCA GTGCCTTGCT AGTAGACAAC CCCACGCCTT TCGGGAACGC AAAGGAAGTG 
ATTGCGATCA AAGACTATTG CCCAAACAAC TTCACCACCC TGAAGTTCTC CAAGGGCGAC 
CACCTCTACG TCTTGGACAC GTCTGGCGGG GAGTGGTGGT ACGCTCACAA CACCACTGAG 
ATGGGCTACA TCCCTTCCTC CTACGTGCAG CCATTGAACT ACCGGAATTC TACCCTGAGT 
GACAGTGGCA TGATTGACAA TCTCCCTGAC AGCCCCGATG AAGTTGCCAA GGAGCTAGAT 
CTCCTAGGGG GCTGGACAGA TGACCAGAAA CAGTCTGGCA GACCCTATAG TAACAACCCC 
TTCTGGAATG GAGTCCGAAC AAACCCTTTT CTGAATGGGA ACGCACAGCC CAGTATGGAT 
GAACTAAACC CCAAGAGTAC TGTGGATTTG CTCCTGTTTG ACACCGGCAC ATCTTCCTTC 
ACTGAATCCA GCTCAGCGAC CACCAACAGC ACCGGCAACA TCTTCGACGA GCTCCCAGCC 
ACCAATGGAA TCCACTTGGA GCAGCCTGTC AAGCGAGACA ACCCCTTCTT CAGAAGCAAG 
CGCTCCTACA GCCTTTCGGA ACTCTCCGTC CTGCAAGCCA AATCAGATGC TCCCCCAACA 
TCCAGCTTCT TCACAGGCTT GAAGTCACCC GCCCCGGAAC AGTTTCAAAG CCGAGAAGAC 
TTCCGAACCG CCTGGCTGAA TCACCGGAAG CTGGCCCGTT CCTGCCATGA CTTGGACCTG 
CTCGGCCAAA GCCCAGGTTG GGGCCAGACC CAAGCAGTGG AGACAAATAT CGTGTGCAAG 
CTTGATAGTT CTGGGGGCTC TGTGCAGCTT CCTGACACCA GCATCAGTAT CCACGTGCCA 
GAGGGCCACG TCGCTCCTGG GGAGACACAG CAGATTTCCA TGAAGGCCTT GCTGGACCCT 
CCGCTGGACC TCAACAGTGA CAGGTCCACC AGCATAAGCC CCGTGGTGGA GGTGAAACTG 
AGCAACTTAG AGGTGAGTAC CTTCATCATC TTGGAGATGA AGGTCTCCGC CGAGGTGAAG 
GGCGACATCT TTAGCAAAAG CACAGTGGTC CTGCAGTGCC TGAGAAGCGA CTCAAAGGAG 
GGGCCTTATG CACCCATCCC CCTCGCCTAC AGCTACGGGG ACACCATACA GGTGCAGCTG 
GACAACCTGG AACCCTGCAT GTACCTGGCC ATCGTCGCCC AGGGCTCCAA CATTCTCTAC 
CCTTCCACCG TGTGGGATTT CATCCACAAG AGGGTCACCG TGGGTCTCTA TGGCCCCAAA 
CACATCCACC CATCCTTCAA GACGGTGGTG ACCATTTTTG GACATGATTG CGCCCCTAAG 
ACCCTCCTGG TCACTGAGGT TACCCGACAG GCTCCCAGTC CTGCCCCCGT GGCCCTACAG 
CTGTGGGGCA AACACCAGTT CATCCTGTCC AGGCCTCAGG ATCTCAGGGT GTGTATGTTC 
TCCAATATGA CCAACTATGA CGTCAAGTCC AACGAGCAAG CCAAGGTGGT CAGAGGGTTC 
CAGATGAAGC TGGGCAAGGT CAGCCGTCTG ATCTTCTCTG TCATCTCCCA GAACCCCAAC 
GAGCTGTCCG ACTTCACGCT GCGGGTGCAG GTCAAGGATG ATCAGGACGC CATCCTCACA 
CAGTTTTGCG TCCAGACTCC ACAGCCACCC CCTAAAAGCG CCATTAAGCC ATCCGGGCAG 
AGGAGGTTTC TTAAGAAGAA TGAAGTTGGG AAGATCATCT TGTCCCCATT TGTTGTCACT 
ACCAAGTATC CGACGTTTCA GGACCGCCCC GTGTCTAGTC TCAAGTTTGG CAAGCTTCTA 
AAGACAGTGG TGCGACAGAA CAAGAGTCAC TACCTGCTGG AGTACAAGAA GGGCGACGTC 
GTGGCCCTGC TCAGCGAGGA GCGCATCCGG CTCAAGGGAC AACTGTGGAC CAAGGAGTGG 
TACATTGGCT ACTATCAGGG CAAGGTGGGC CTGGTGCACA CCAAGAACGT GCTGGTTGTC 
GGCAAGGCCC GGCCCAGCCT GTTCTCAGGG CCCGAGCTGA GCACCTCGGT GTTGCTGGAG 
CAAATCCTGC GGCCCTGCAA GTTCCTCACC TACATCTACG CCTCCGTGCG GACCTTGCTC 
ATGGAGAACA TCAGCAGCTG GCGGGCCTTT GCTGACGCCC TGGGTTACGG AAACCTGCCC 
CTCACCTTCT TCTGCCGGGC AGAGCTGGAC AGCGAGCCGG AGCGGGTGGC GTCTGTTCTA 
GAAAAGCTGA AGGAAGATTG TAACAACCCT GACAACAAGG ACCGGAAGTC CTTCCAGAAG 
GAGCTGGTGA TGGCTTTGCT GAAAATGGAC TGTCAGGGCC TGGTGGTCAG ACTCATCCAG 
GACTTTGTGC TCCTGACCAC AGCCGTCGAA GTGGCACAGC GCTGGAGGGA ACTGGCCGAG 
AAGCTAGCCA AGGTCTCCAA GCAACAGATG GATGCCTATG AGTCTCCTCA CCGAGACAGG 
AATGGGGTGG TAGACAGTGA GGCCATGTGG AAACCCGCCT ATGACTTTTT ACTCACCTGG 
AGCCACCAGA TTGGGGACAG CTACCGAGAT GTCATCCAAG AGCTGCACAT AGGCCTGGAC 
AAGATGAAGA ACCCCATCAC CAGGCGCTGG AAGCACCTCA CGGGGACACT GATCCTGGTG 
AACTCACTGG ACATCCTGAG GGCAGCTGCC TTCAGCCCCG CGGACCATGA TGACTTTGTG 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073184.3
CDS	383..3268
Translation	MAAQRIRAANSSGLPRCKSEGTLIDLSEGFSETSFNDVKVPSPSALLVDNPTPFGNAKEVIAIKDYCPNNFTTLKFSKGDHLYVLDTSGGEWWYAHNTTEMGYIPSSYVQPLNYRNSTLSDSGMIDNLPDSPDEVAKELDLLGGWTDDQKQSGRPYSNNPFWNGVRTNPFLNGNAQPSMDELNPKSTVDLLLFDTGTSSFTESSSATTNSTGNIFDELPATNGIHLEQPVKRDNPFFRSKRSYSLSELSVLQAKSDAPPTSSFFTGLKSPAPEQFQSREDFRTAWLNHRKLARSCHDLDLLGQSPGWGQTQAVETNIVCKLDSSGGSVQLPDTSISIHVPEGHVAPGETQQISMKALLDPPLDLNSDRSTSISPVVEVKLSNLEVSTFIILEMKVSAEVKGDIFSKSTVVLQCLRSDSKEGPYAPIPLAYSYGDTIQVQLDNLEPCMYLAIVAQGSNILYPSTVWDFIHKRVTVGLYGPKHIHPSFKTVVTIFGHDCAPKTLLVTEVTRQAPSPAPVALQLWGKHQFILSRPQDLRVCMFSNMTNYDVKSNEQAKVVRGFQMKLGKVSRLIFSVISQNPNELSDFTLRVQVKDDQDAILTQFCVQTPQPPPKSAIKPSGQRRFLKKNEVGKIILSPFVVTTKYPTFQDRPVSSLKFGKLLKTVVRQNKSHYLLEYKKGDVVALLSEERIRLKGQLWTKEWYIGYYQGKVGLVHTKNVLVVGKARPSLFSGPELSTSVLLEQILRPCKFLTYIYASVRTLLMENISSWRAFADALGYGNLPLTFFCRAELDSEPERVASVLEKLKEDCNNPDNKDRKSFQKELVMALLKMDCQGLVVRLIQDFVLLTTAVEVAQRWRELAEKLAKVSKQQMDAYESPHRDRNGVVDSEAMWKPAYDFLLTWSHQIGDSYRDVIQELHIGLDKMKNPITRRWKHLTGTLILVNSLDILRAAAFSPADHDDFVI

Target ORF information:

RefSeq Version	NM_022693.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SH3-domain binding protein 4 (Sh3bp4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022693.4

ORF Insert Sequence:

ATGGCAGCCC AGCGCATCCG GGCAGCCAAC TCCAGTGGCC TCCCTCGGTG CAAGTCGGAG 
GGGACTCTGA TCGACCTGAG CGAGGGCTTC TCAGAGACAA GCTTTAATGA TGTCAAAGTG 
CCTTCCCCCA GTGCCTTGCT AGTAGACAAC CCCACGCCTT TCGGGAACGC AAAGGAAGTG 
ATTGCGATCA AAGACTATTG CCCAAACAAC TTCACCACCC TGAAGTTCTC CAAGGGCGAC 
CACCTCTACG TCTTGGACAC GTCTGGCGGG GAGTGGTGGT ACGCTCACAA CACCACTGAG 
ATGGGCTACA TCCCTTCCTC CTACGTGCAG CCATTGAACT ACCGGAATTC TACCCTGAGT 
GACAGTGGCA TGATTGACAA TCTCCCTGAC AGCCCCGATG AAGTTGCCAA GGAGCTAGAT 
CTCCTAGGGG GCTGGACAGA TGACCAGAAA CAGTCTGGCA GACCCTATAG TAACAACCCC 
TTCTGGAATG GAGTCCGAAC AAACCCTTTT CTGAATGGGA ACGCACAGCC CAGTATGGAT 
GAACTAAACC CCAAGAGTAC TGTGGATTTG CTCCTGTTTG ACACCGGCAC ATCTTCCTTC 
ACTGAATCCA GCTCAGCGAC CACCAACAGC ACCGGCAACA TCTTCGACGA GCTCCCAGCC 
ACCAATGGAA TCCACTTGGA GCAGCCTGTC AAGCGAGACA ACCCCTTCTT CAGAAGCAAG 
CGCTCCTACA GCCTTTCGGA ACTCTCCGTC CTGCAAGCCA AATCAGATGC TCCCCCAACA 
TCCAGCTTCT TCACAGGCTT GAAGTCACCC GCCCCGGAAC AGTTTCAAAG CCGAGAAGAC 
TTCCGAACCG CCTGGCTGAA TCACCGGAAG CTGGCCCGTT CCTGCCATGA CTTGGACCTG 
CTCGGCCAAA GCCCAGGTTG GGGCCAGACC CAAGCAGTGG AGACAAATAT CGTGTGCAAG 
CTTGATAGTT CTGGGGGCTC TGTGCAGCTT CCTGACACCA GCATCAGTAT CCACGTGCCA 
GAGGGCCACG TCGCTCCTGG GGAGACACAG CAGATTTCCA TGAAGGCCTT GCTGGACCCT 
CCGCTGGACC TCAACAGTGA CAGGTCCACC AGCATAAGCC CCGTGGTGGA GGTGAAACTG 
AGCAACTTAG AGGTGAGTAC CTTCATCATC TTGGAGATGA AGGTCTCCGC CGAGGTGAAG 
GGCGACATCT TTAGCAAAAG CACAGTGGTC CTGCAGTGCC TGAGAAGCGA CTCAAAGGAG 
GGGCCTTATG CACCCATCCC CCTCGCCTAC AGCTACGGGG ACACCATACA GGTGCAGCTG 
GACAACCTGG AACCCTGCAT GTACCTGGCC ATCGTCGCCC AGGGCTCCAA CATTCTCTAC 
CCTTCCACCG TGTGGGATTT CATCCACAAG AGGGTCACCG TGGGTCTCTA TGGCCCCAAA 
CACATCCACC CATCCTTCAA GACGGTGGTG ACCATTTTTG GACATGATTG CGCCCCTAAG 
ACCCTCCTGG TCACTGAGGT TACCCGACAG GCTCCCAGTC CTGCCCCCGT GGCCCTACAG 
CTGTGGGGCA AACACCAGTT CATCCTGTCC AGGCCTCAGG ATCTCAGGGT GTGTATGTTC 
TCCAATATGA CCAACTATGA CGTCAAGTCC AACGAGCAAG CCAAGGTGGT CAGAGGGTTC 
CAGATGAAGC TGGGCAAGGT CAGCCGTCTG ATCTTCTCTG TCATCTCCCA GAACCCCAAC 
GAGCTGTCCG ACTTCACGCT GCGGGTGCAG GTCAAGGATG ATCAGGACGC CATCCTCACA 
CAGTTTTGCG TCCAGACTCC ACAGCCACCC CCTAAAAGCG CCATTAAGCC ATCCGGGCAG 
AGGAGGTTTC TTAAGAAGAA TGAAGTTGGG AAGATCATCT TGTCCCCATT TGTTGTCACT 
ACCAAGTATC CGACGTTTCA GGACCGCCCC GTGTCTAGTC TCAAGTTTGG CAAGCTTCTA 
AAGACAGTGG TGCGACAGAA CAAGAGTCAC TACCTGCTGG AGTACAAGAA GGGCGACGTC 
GTGGCCCTGC TCAGCGAGGA GCGCATCCGG CTCAAGGGAC AACTGTGGAC CAAGGAGTGG 
TACATTGGCT ACTATCAGGG CAAGGTGGGC CTGGTGCACA CCAAGAACGT GCTGGTTGTC 
GGCAAGGCCC GGCCCAGCCT GTTCTCAGGG CCCGAGCTGA GCACCTCGGT GTTGCTGGAG 
CAAATCCTGC GGCCCTGCAA GTTCCTCACC TACATCTACG CCTCCGTGCG GACCTTGCTC 
ATGGAGAACA TCAGCAGCTG GCGGGCCTTT GCTGACGCCC TGGGTTACGG AAACCTGCCC 
CTCACCTTCT TCTGCCGGGC AGAGCTGGAC AGCGAGCCGG AGCGGGTGGC GTCTGTTCTA 
GAAAAGCTGA AGGAAGATTG TAACAACCCT GACAACAAGG ACCGGAAGTC CTTCCAGAAG 
GAGCTGGTGA TGGCTTTGCT GAAAATGGAC TGTCAGGGCC TGGTGGTCAG ACTCATCCAG 
GACTTTGTGC TCCTGACCAC AGCCGTCGAA GTGGCACAGC GCTGGAGGGA ACTGGCCGAG 
AAGCTAGCCA AGGTCTCCAA GCAACAGATG GATGCCTATG AGTCTCCTCA CCGAGACAGG 
AATGGGGTGG TAGACAGTGA GGCCATGTGG AAACCCGCCT ATGACTTTTT ACTCACCTGG 
AGCCACCAGA TTGGGGACAG CTACCGAGAT GTCATCCAAG AGCTGCACAT AGGCCTGGAC 
AAGATGAAGA ACCCCATCAC CAGGCGCTGG AAGCACCTCA CGGGGACACT GATCCTGGTG 
AACTCACTGG ACATCCTGAG GGCAGCTGCC TTCAGCCCCG CGGACCATGA TGACTTTGTG 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sh3bp4 ( XM_008767298.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765520.1 Rattus norvegicus SH3-domain binding protein 4 (Sh3bp4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa06268
Clone ID Related Accession (Same CDS sequence)	NM_022693.4 , XM_008767298.2
Accession Version	XM_008767298.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2886bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	SH3 domain-binding protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767298.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGCCC AGCGCATCCG GGCAGCCAAC TCCAGTGGCC TCCCTCGGTG CAAGTCGGAG 
GGGACTCTGA TCGACCTGAG CGAGGGCTTC TCAGAGACAA GCTTTAATGA TGTCAAAGTG 
CCTTCCCCCA GTGCCTTGCT AGTAGACAAC CCCACGCCTT TCGGGAACGC AAAGGAAGTG 
ATTGCGATCA AAGACTATTG CCCAAACAAC TTCACCACCC TGAAGTTCTC CAAGGGCGAC 
CACCTCTACG TCTTGGACAC GTCTGGCGGG GAGTGGTGGT ACGCTCACAA CACCACTGAG 
ATGGGCTACA TCCCTTCCTC CTACGTGCAG CCATTGAACT ACCGGAATTC TACCCTGAGT 
GACAGTGGCA TGATTGACAA TCTCCCTGAC AGCCCCGATG AAGTTGCCAA GGAGCTAGAT 
CTCCTAGGGG GCTGGACAGA TGACCAGAAA CAGTCTGGCA GACCCTATAG TAACAACCCC 
TTCTGGAATG GAGTCCGAAC AAACCCTTTT CTGAATGGGA ACGCACAGCC CAGTATGGAT 
GAACTAAACC CCAAGAGTAC TGTGGATTTG CTCCTGTTTG ACACCGGCAC ATCTTCCTTC 
ACTGAATCCA GCTCAGCGAC CACCAACAGC ACCGGCAACA TCTTCGACGA GCTCCCAGCC 
ACCAATGGAA TCCACTTGGA GCAGCCTGTC AAGCGAGACA ACCCCTTCTT CAGAAGCAAG 
CGCTCCTACA GCCTTTCGGA ACTCTCCGTC CTGCAAGCCA AATCAGATGC TCCCCCAACA 
TCCAGCTTCT TCACAGGCTT GAAGTCACCC GCCCCGGAAC AGTTTCAAAG CCGAGAAGAC 
TTCCGAACCG CCTGGCTGAA TCACCGGAAG CTGGCCCGTT CCTGCCATGA CTTGGACCTG 
CTCGGCCAAA GCCCAGGTTG GGGCCAGACC CAAGCAGTGG AGACAAATAT CGTGTGCAAG 
CTTGATAGTT CTGGGGGCTC TGTGCAGCTT CCTGACACCA GCATCAGTAT CCACGTGCCA 
GAGGGCCACG TCGCTCCTGG GGAGACACAG CAGATTTCCA TGAAGGCCTT GCTGGACCCT 
CCGCTGGACC TCAACAGTGA CAGGTCCACC AGCATAAGCC CCGTGGTGGA GGTGAAACTG 
AGCAACTTAG AGGTGAGTAC CTTCATCATC TTGGAGATGA AGGTCTCCGC CGAGGTGAAG 
GGCGACATCT TTAGCAAAAG CACAGTGGTC CTGCAGTGCC TGAGAAGCGA CTCAAAGGAG 
GGGCCTTATG CACCCATCCC CCTCGCCTAC AGCTACGGGG ACACCATACA GGTGCAGCTG 
GACAACCTGG AACCCTGCAT GTACCTGGCC ATCGTCGCCC AGGGCTCCAA CATTCTCTAC 
CCTTCCACCG TGTGGGATTT CATCCACAAG AGGGTCACCG TGGGTCTCTA TGGCCCCAAA 
CACATCCACC CATCCTTCAA GACGGTGGTG ACCATTTTTG GACATGATTG CGCCCCTAAG 
ACCCTCCTGG TCACTGAGGT TACCCGACAG GCTCCCAGTC CTGCCCCCGT GGCCCTACAG 
CTGTGGGGCA AACACCAGTT CATCCTGTCC AGGCCTCAGG ATCTCAGGGT GTGTATGTTC 
TCCAATATGA CCAACTATGA CGTCAAGTCC AACGAGCAAG CCAAGGTGGT CAGAGGGTTC 
CAGATGAAGC TGGGCAAGGT CAGCCGTCTG ATCTTCTCTG TCATCTCCCA GAACCCCAAC 
GAGCTGTCCG ACTTCACGCT GCGGGTGCAG GTCAAGGATG ATCAGGACGC CATCCTCACA 
CAGTTTTGCG TCCAGACTCC ACAGCCACCC CCTAAAAGCG CCATTAAGCC ATCCGGGCAG 
AGGAGGTTTC TTAAGAAGAA TGAAGTTGGG AAGATCATCT TGTCCCCATT TGTTGTCACT 
ACCAAGTATC CGACGTTTCA GGACCGCCCC GTGTCTAGTC TCAAGTTTGG CAAGCTTCTA 
AAGACAGTGG TGCGACAGAA CAAGAGTCAC TACCTGCTGG AGTACAAGAA GGGCGACGTC 
GTGGCCCTGC TCAGCGAGGA GCGCATCCGG CTCAAGGGAC AACTGTGGAC CAAGGAGTGG 
TACATTGGCT ACTATCAGGG CAAGGTGGGC CTGGTGCACA CCAAGAACGT GCTGGTTGTC 
GGCAAGGCCC GGCCCAGCCT GTTCTCAGGG CCCGAGCTGA GCACCTCGGT GTTGCTGGAG 
CAAATCCTGC GGCCCTGCAA GTTCCTCACC TACATCTACG CCTCCGTGCG GACCTTGCTC 
ATGGAGAACA TCAGCAGCTG GCGGGCCTTT GCTGACGCCC TGGGTTACGG AAACCTGCCC 
CTCACCTTCT TCTGCCGGGC AGAGCTGGAC AGCGAGCCGG AGCGGGTGGC GTCTGTTCTA 
GAAAAGCTGA AGGAAGATTG TAACAACCCT GACAACAAGG ACCGGAAGTC CTTCCAGAAG 
GAGCTGGTGA TGGCTTTGCT GAAAATGGAC TGTCAGGGCC TGGTGGTCAG ACTCATCCAG 
GACTTTGTGC TCCTGACCAC AGCCGTCGAA GTGGCACAGC GCTGGAGGGA ACTGGCCGAG 
AAGCTAGCCA AGGTCTCCAA GCAACAGATG GATGCCTATG AGTCTCCTCA CCGAGACAGG 
AATGGGGTGG TAGACAGTGA GGCCATGTGG AAACCCGCCT ATGACTTTTT ACTCACCTGG 
AGCCACCAGA TTGGGGACAG CTACCGAGAT GTCATCCAAG AGCTGCACAT AGGCCTGGAC 
AAGATGAAGA ACCCCATCAC CAGGCGCTGG AAGCACCTCA CGGGGACACT GATCCTGGTG 
AACTCACTGG ACATCCTGAG GGCAGCTGCC TTCAGCCCCG CGGACCATGA TGACTTTGTG 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765520.1
CDS	567..3452
Translation	MAAQRIRAANSSGLPRCKSEGTLIDLSEGFSETSFNDVKVPSPSALLVDNPTPFGNAKEVIAIKDYCPNNFTTLKFSKGDHLYVLDTSGGEWWYAHNTTEMGYIPSSYVQPLNYRNSTLSDSGMIDNLPDSPDEVAKELDLLGGWTDDQKQSGRPYSNNPFWNGVRTNPFLNGNAQPSMDELNPKSTVDLLLFDTGTSSFTESSSATTNSTGNIFDELPATNGIHLEQPVKRDNPFFRSKRSYSLSELSVLQAKSDAPPTSSFFTGLKSPAPEQFQSREDFRTAWLNHRKLARSCHDLDLLGQSPGWGQTQAVETNIVCKLDSSGGSVQLPDTSISIHVPEGHVAPGETQQISMKALLDPPLDLNSDRSTSISPVVEVKLSNLEVSTFIILEMKVSAEVKGDIFSKSTVVLQCLRSDSKEGPYAPIPLAYSYGDTIQVQLDNLEPCMYLAIVAQGSNILYPSTVWDFIHKRVTVGLYGPKHIHPSFKTVVTIFGHDCAPKTLLVTEVTRQAPSPAPVALQLWGKHQFILSRPQDLRVCMFSNMTNYDVKSNEQAKVVRGFQMKLGKVSRLIFSVISQNPNELSDFTLRVQVKDDQDAILTQFCVQTPQPPPKSAIKPSGQRRFLKKNEVGKIILSPFVVTTKYPTFQDRPVSSLKFGKLLKTVVRQNKSHYLLEYKKGDVVALLSEERIRLKGQLWTKEWYIGYYQGKVGLVHTKNVLVVGKARPSLFSGPELSTSVLLEQILRPCKFLTYIYASVRTLLMENISSWRAFADALGYGNLPLTFFCRAELDSEPERVASVLEKLKEDCNNPDNKDRKSFQKELVMALLKMDCQGLVVRLIQDFVLLTTAVEVAQRWRELAEKLAKVSKQQMDAYESPHRDRNGVVDSEAMWKPAYDFLLTWSHQIGDSYRDVIQELHIGLDKMKNPITRRWKHLTGTLILVNSLDILRAAAFSPADHDDFVI

Target ORF information:

RefSeq Version	XM_008767298.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SH3-domain binding protein 4 (Sh3bp4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767298.2

ORF Insert Sequence:

ATGGCAGCCC AGCGCATCCG GGCAGCCAAC TCCAGTGGCC TCCCTCGGTG CAAGTCGGAG 
GGGACTCTGA TCGACCTGAG CGAGGGCTTC TCAGAGACAA GCTTTAATGA TGTCAAAGTG 
CCTTCCCCCA GTGCCTTGCT AGTAGACAAC CCCACGCCTT TCGGGAACGC AAAGGAAGTG 
ATTGCGATCA AAGACTATTG CCCAAACAAC TTCACCACCC TGAAGTTCTC CAAGGGCGAC 
CACCTCTACG TCTTGGACAC GTCTGGCGGG GAGTGGTGGT ACGCTCACAA CACCACTGAG 
ATGGGCTACA TCCCTTCCTC CTACGTGCAG CCATTGAACT ACCGGAATTC TACCCTGAGT 
GACAGTGGCA TGATTGACAA TCTCCCTGAC AGCCCCGATG AAGTTGCCAA GGAGCTAGAT 
CTCCTAGGGG GCTGGACAGA TGACCAGAAA CAGTCTGGCA GACCCTATAG TAACAACCCC 
TTCTGGAATG GAGTCCGAAC AAACCCTTTT CTGAATGGGA ACGCACAGCC CAGTATGGAT 
GAACTAAACC CCAAGAGTAC TGTGGATTTG CTCCTGTTTG ACACCGGCAC ATCTTCCTTC 
ACTGAATCCA GCTCAGCGAC CACCAACAGC ACCGGCAACA TCTTCGACGA GCTCCCAGCC 
ACCAATGGAA TCCACTTGGA GCAGCCTGTC AAGCGAGACA ACCCCTTCTT CAGAAGCAAG 
CGCTCCTACA GCCTTTCGGA ACTCTCCGTC CTGCAAGCCA AATCAGATGC TCCCCCAACA 
TCCAGCTTCT TCACAGGCTT GAAGTCACCC GCCCCGGAAC AGTTTCAAAG CCGAGAAGAC 
TTCCGAACCG CCTGGCTGAA TCACCGGAAG CTGGCCCGTT CCTGCCATGA CTTGGACCTG 
CTCGGCCAAA GCCCAGGTTG GGGCCAGACC CAAGCAGTGG AGACAAATAT CGTGTGCAAG 
CTTGATAGTT CTGGGGGCTC TGTGCAGCTT CCTGACACCA GCATCAGTAT CCACGTGCCA 
GAGGGCCACG TCGCTCCTGG GGAGACACAG CAGATTTCCA TGAAGGCCTT GCTGGACCCT 
CCGCTGGACC TCAACAGTGA CAGGTCCACC AGCATAAGCC CCGTGGTGGA GGTGAAACTG 
AGCAACTTAG AGGTGAGTAC CTTCATCATC TTGGAGATGA AGGTCTCCGC CGAGGTGAAG 
GGCGACATCT TTAGCAAAAG CACAGTGGTC CTGCAGTGCC TGAGAAGCGA CTCAAAGGAG 
GGGCCTTATG CACCCATCCC CCTCGCCTAC AGCTACGGGG ACACCATACA GGTGCAGCTG 
GACAACCTGG AACCCTGCAT GTACCTGGCC ATCGTCGCCC AGGGCTCCAA CATTCTCTAC 
CCTTCCACCG TGTGGGATTT CATCCACAAG AGGGTCACCG TGGGTCTCTA TGGCCCCAAA 
CACATCCACC CATCCTTCAA GACGGTGGTG ACCATTTTTG GACATGATTG CGCCCCTAAG 
ACCCTCCTGG TCACTGAGGT TACCCGACAG GCTCCCAGTC CTGCCCCCGT GGCCCTACAG 
CTGTGGGGCA AACACCAGTT CATCCTGTCC AGGCCTCAGG ATCTCAGGGT GTGTATGTTC 
TCCAATATGA CCAACTATGA CGTCAAGTCC AACGAGCAAG CCAAGGTGGT CAGAGGGTTC 
CAGATGAAGC TGGGCAAGGT CAGCCGTCTG ATCTTCTCTG TCATCTCCCA GAACCCCAAC 
GAGCTGTCCG ACTTCACGCT GCGGGTGCAG GTCAAGGATG ATCAGGACGC CATCCTCACA 
CAGTTTTGCG TCCAGACTCC ACAGCCACCC CCTAAAAGCG CCATTAAGCC ATCCGGGCAG 
AGGAGGTTTC TTAAGAAGAA TGAAGTTGGG AAGATCATCT TGTCCCCATT TGTTGTCACT 
ACCAAGTATC CGACGTTTCA GGACCGCCCC GTGTCTAGTC TCAAGTTTGG CAAGCTTCTA 
AAGACAGTGG TGCGACAGAA CAAGAGTCAC TACCTGCTGG AGTACAAGAA GGGCGACGTC 
GTGGCCCTGC TCAGCGAGGA GCGCATCCGG CTCAAGGGAC AACTGTGGAC CAAGGAGTGG 
TACATTGGCT ACTATCAGGG CAAGGTGGGC CTGGTGCACA CCAAGAACGT GCTGGTTGTC 
GGCAAGGCCC GGCCCAGCCT GTTCTCAGGG CCCGAGCTGA GCACCTCGGT GTTGCTGGAG 
CAAATCCTGC GGCCCTGCAA GTTCCTCACC TACATCTACG CCTCCGTGCG GACCTTGCTC 
ATGGAGAACA TCAGCAGCTG GCGGGCCTTT GCTGACGCCC TGGGTTACGG AAACCTGCCC 
CTCACCTTCT TCTGCCGGGC AGAGCTGGAC AGCGAGCCGG AGCGGGTGGC GTCTGTTCTA 
GAAAAGCTGA AGGAAGATTG TAACAACCCT GACAACAAGG ACCGGAAGTC CTTCCAGAAG 
GAGCTGGTGA TGGCTTTGCT GAAAATGGAC TGTCAGGGCC TGGTGGTCAG ACTCATCCAG 
GACTTTGTGC TCCTGACCAC AGCCGTCGAA GTGGCACAGC GCTGGAGGGA ACTGGCCGAG 
AAGCTAGCCA AGGTCTCCAA GCAACAGATG GATGCCTATG AGTCTCCTCA CCGAGACAGG 
AATGGGGTGG TAGACAGTGA GGCCATGTGG AAACCCGCCT ATGACTTTTT ACTCACCTGG 
AGCCACCAGA TTGGGGACAG CTACCGAGAT GTCATCCAAG AGCTGCACAT AGGCCTGGAC 
AAGATGAAGA ACCCCATCAC CAGGCGCTGG AAGCACCTCA CGGGGACACT GATCCTGGTG 
AACTCACTGG ACATCCTGAG GGCAGCTGCC TTCAGCCCCG CGGACCATGA TGACTTTGTG 
ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

dRAGging amino acid-mTORC1 signaling by SH3BP4.
Molecules and cells35(1)1-6(2013 Jan)
Kim YM,Kim DH

SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.
Molecular cell46(6)833-46(2012 Jun)
Kim YM,Stone M,Hwang TH,Kim YG,Dunlevy JR,Griffin TJ,Kim DH

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

TTP specifically regulates the internalization of the transferrin receptor.
Cell123(5)875-88(2005 Dec)
Tosoni D,Puri C,Confalonieri S,Salcini AE,De Camilli P,Tacchetti C,Di Fiore PP

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

[email protected]

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Sh3bp4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム