Slc26a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc26a1
Entrez Gene ID	64076
Full Name	solute carrier family 26 member 1
Synonyms	sat-1
General protein information	Preferred Names solute carrier family 26 member 1 Names sulfate anion transporter 1 canalicular sulfate transporter solute carrier family 26 (anion exchanger), member 1 solute carrier family 26 (sulfate transporter), member 1 sulfate/carbonate antiporter
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p22
Summary	sulfate transporter [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022287.2	NP_071623.2	sulfate anion transporter 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC26A1	XP_003310259.1
Mus musculus (house mouse)	Slc26a1	NP_777359.3
Rattus norvegicus (Norway rat)	Slc26a1	NP_071623.2
Caenorhabditis elegans (roundworm)	sulp-2	NP_508944.1
Homo sapiens (human)	SLC26A1	NP_071325.2
Canis lupus familiaris (dog)	SLC26A1	XP_545984.3
Bos taurus (cattle)	SLC26A1	XP_005208341.1
	SLC26A1	XP_001093208.2

Gene Ontology
Bibliography

Related articles in PubMed

SLC26A Gene Family Participate in pH Regulation during Enamel Maturation.
Yin K, Lei Y, Wen X, Lacruz RS, Soleimani M, Kurtz I, Snead ML, White SN, Paine ML
PloS one10(12)e0144703(2015)

The liver and kidney expression of sulfate anion transporter sat-1 in rats exhibits male-dominant gender differences.
Brzica H, Breljak D, Krick W, Lovri? M, Burckhardt G, Burckhardt BC, Saboli? I
Pflugers Archiv : European journal of physiology457(6)1381-92(2009 Apr)

Localization of the sulfate/anion exchanger in the rat liver.
Quondamatteo F, Krick W, Hagos Y, Kr?ger MH, Neubauer-Saile K, Herken R, Ramadori G, Burckhardt G, Burckhardt BC
American journal of physiology. Gastrointestinal and liver physiology290(5)G1075-81(2006 May)

A dileucine motif targets the sulfate anion transporter sat-1 to the basolateral membrane in renal cell lines.
Regeer RR, Markovich D
American journal of physiology. Cell physiology287(2)C365-72(2004 Aug)

The mouse sulfate anion transporter gene Sat1 (Slc26a1): cloning, tissue distribution, gene structure, functional characterization, and transcriptional regulation thyroid hormone.
Lee A, Beck L, Markovich D
DNA and cell biology22(1)19-31(2003 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Slc26a1, Slc26a6 and Slc26a7 are novel participants in the extracellular transport of bicarbonate during enamel maturation.
Title: SLC26A Gene Family Participate in pH Regulation during Enamel Maturation.

Gender differences (males > females) in the expression of sat-1 protein in rat liver (and, possibly, kidneys) are caused by the female sex-hormone-driven inhibition at the posttranscriptional level
Title: The liver and kidney expression of sulfate anion transporter sat-1 in rats exhibits male-dominant gender differences.

Sat-1 may be responsible for the uptake of inorganic sulfate from the blood into hepatocytes to enable sulfation reactions. In hepatocytes and endothelial cells, sat-1 may also supply sulfate for proteoglycan synthesis.
Title: Localization of the sulfate/anion exchanger in the rat liver.

Elimination of a dileucine motif at position 677/678 resulted in the loss of basolateral sorting, suggesting that this motif is required for sat-1 targeting to the basolateral membrane.
Title: A dileucine motif targets the sulfate anion transporter sat-1 to the basolateral membrane in renal cell lines.

The following Slc26a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc26a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05624	NM_022287.2 Latest version!	Rattus norvegicus solute carrier family 26 member 1 (Slc26a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc26a1 ( NM_022287.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071623.2 Rattus norvegicus solute carrier family 26 member 1 (Slc26a1), mRNA.

Price & Availability↑

CloneID	ORa05624
Clone ID Related Accession (Same CDS sequence)	NM_022287.2
Accession Version	NM_022287.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2112bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Rattus norvegicus(Norway rat)
Product	sulfate anion transporter 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085735.1. On Jun 3, 2007 this sequence version replaced NM_022287.1. ##Evidence-Data-START## Transcript exon combination :: BC085735.1, L23413.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGATGCTT CTCCTGAGCC CCCGCAGAAG GGCGGGACAC TGGTACTGGT CCGACGGCAG 
CCCCCTGTGT CCCAGGGCTT GCTGGAAACA CTGAAGGCCA GGCTGAAGAA GAGCTGCACC 
TGCAGTATGC CATGCGCTCA GGCTCTGGTG CAAGGTCTGT TTCCTGTCAT ACGCTGGCTG 
CCCCAGTACC GCCTTAAGGA ATACCTGGCA GGTGATGTCA TGTCGGGATT GGTCATTGGC 
ATTATCCTGG TGCCACAGGC CATAGCCTAC TCACTGCTGG CTGGGTTGCA GCCCATCTAC 
AGTCTCTACA CTTCCTTCTT CGCCAACCTT ATCTACTTCC TCATGGGTAC CTCCCGCCAC 
GTTAATGTGG GCATCTTCAG CCTGCTGTGT CTCATGGTGG GTCAGGTGGT GGACCGAGAA 
CTCCAGTTGG CTGGCTTTGA CCCCTCCCAG GATTCTCTAG GGCCCGGGAA CAATGACAGC 
ACCCTCAACA ACACAGCCAC ACTGACAGTT GGGCTACAGG ACTGTGGGCG GGACTGCCAT 
GCCATTCGTA TCGCCACTGC CCTCACTCTG ATGGCCGGGC TTTATCAGGT CCTCATGGGG 
ATCCTCCGGC TGGGCTTCGT GTCTACCTAT CTCTCGCAAC CCCTGCTCGA TGGCTTTGCT 
ATGGGAGCTT CTGTGACCAT CTTGACTTCT CAGGCTAAAC ACCTGCTGGG CGTGCGGATC 
CCTCGGCACC AGGGCCTAGG CATGGTGATC CACACTTGGC TGAGCTTGCT GCAGAACGTG 
GGACAGGCTA ATCTGTGTGA TGTGGTCACC AGTGCCGTGT GCCTGGCAGT GCTGCTGACA 
GCTAAGGAAC TCTCGGATCG CTATCGACAC TATCTGAAAG TGCCAGTGCC CACAGAGCTA 
TTAGTTATTG TGGTGGCCAC GATTGCGTCC CATTTTGGAC AGCTCCATAC ACGGTTTGGC 
TCGAGTGTGG CCGGCAACAT TCCCACTGGT TTTGTGGCCC CACAGATACC AGACCCTAAG 
ATAATGTGGA GTGTGGCCCT GGATGCCATG TCCCTGGCCC TCGTGGGCTC AGCCTTCTCC 
ATCTCCTTGG CAGAAATGTT TGCACGTAGT CATGGCTACT CTGTCAGTGC CAACCAAGAG 
CTGCTAGCTG TGGGCTGTTG CAACGTGCTG CCTGCCTTCT TCCACTGTTT TGCCACTAGT 
GCTGCTCTGT CCAAAACTCT GGTGAAGATA GCCACTGGCT GCCAGACCCA GTTGTCCAGT 
GTGGTCAGTG CTGCTGTGGT GTTGCTGGTG CTGCTGGTGC TGGCGCCATT GTTTCACGAT 
CTGCAGCGGT GTGTGTTAGC TTGCATCATT GTCGTCAGCC TGAGGGGGGC GCTGCGCAAG 
GTGAAGGATC TCCCACAACT TTGGCGGCTA AGCCCTGCGG ACGCACTGGT CTGGGTGGCT 
ACTGCAGCGA CCTGTGTTCT AGTCAGCATC GAGGCTGGGC TATTAGCTGG GGTGTTCTTC 
TCACTGCTCA GCCTGGCAGG CCGCACGCAG CGTCCACGGG CTGCCCTTCT GGCTCGAATT 
GGAGACTCGA CCTTCTATGA GGATGCTGCT GAGTTTGAGG GCCTCCTGCC CCCGCCCGAG 
GTGCGAGTGT TCCGTTTCAC AGGTCCGCTC TACTATGCCA ACAAGGATTT CTTCCTTCGG 
TCACTCTACA GTCTGACAGG GCTGGATGCT GGGTACTCAG CCACCAGGAA GGATCGGGGC 
ACAGAGGTGG GTGTCAGTAA CAGAAGTCTT GTTGACCGCA AGGATCTGGG TTCAGTGAGC 
AGTGGGGATG GGCTGGTTGT ACCCCTGGCA TTTGGTTTCC ACACAGTGGT CATTGACTGT 
GCACCACTGC TGTTCCTGGA TGTGGCTGGC ATGGCCACAT TGAAGGACCT GCGCAAAAAC 
TACAGGGCCC TGGACATCAC CCTGCTTCTG GCTTGCTGCA GTCCCTCAGT GAGAGACACA 
CTGAGAAAAG GGGGCTTCCT TGGGGAAGAC CAGGGAACTG AAGAGGAGCT GCTGTTCCCC 
AGTGTACACA GCGCTGTGGA GACAGCATGT GCCCGCCGTG AGGAGCTGAT GGCTGCTGAC 
TCTGCCCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071623.2
CDS	46..2157
Translation	MDASPEPPQKGGTLVLVRRQPPVSQGLLETLKARLKKSCTCSMPCAQALVQGLFPVIRWLPQYRLKEYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVVDRELQLAGFDPSQDSLGPGNNDSTLNNTATLTVGLQDCGRDCHAIRIATALTLMAGLYQVLMGILRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHLLGVRIPRHQGLGMVIHTWLSLLQNVGQANLCDVVTSAVCLAVLLTAKELSDRYRHYLKVPVPTELLVIVVATIASHFGQLHTRFGSSVAGNIPTGFVAPQIPDPKIMWSVALDAMSLALVGSAFSISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAAVVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSPADALVWVATAATCVLVSIEAGLLAGVFFSLLSLAGRTQRPRAALLARIGDSTFYEDAAEFEGLLPPPEVRVFRFTGPLYYANKDFFLRSLYSLTGLDAGYSATRKDRGTEVGVSNRSLVDRKDLGSVSSGDGLVVPLAFGFHTVVIDCAPLLFLDVAGMATLKDLRKNYRALDITLLLACCSPSVRDTLRKGGFLGEDQGTEEELLFPSVHSAVETACARREELMAADSAL

Target ORF information:

RefSeq Version	NM_022287.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 26 member 1 (Slc26a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022287.2

ORF Insert Sequence:

ATGGATGCTT CTCCTGAGCC CCCGCAGAAG GGCGGGACAC TGGTACTGGT CCGACGGCAG 
CCCCCTGTGT CCCAGGGCTT GCTGGAAACA CTGAAGGCCA GGCTGAAGAA GAGCTGCACC 
TGCAGTATGC CATGCGCTCA GGCTCTGGTG CAAGGTCTGT TTCCTGTCAT ACGCTGGCTG 
CCCCAGTACC GCCTTAAGGA ATACCTGGCA GGTGATGTCA TGTCGGGATT GGTCATTGGC 
ATTATCCTGG TGCCACAGGC CATAGCCTAC TCACTGCTGG CTGGGTTGCA GCCCATCTAC 
AGTCTCTACA CTTCCTTCTT CGCCAACCTT ATCTACTTCC TCATGGGTAC CTCCCGCCAC 
GTTAATGTGG GCATCTTCAG CCTGCTGTGT CTCATGGTGG GTCAGGTGGT GGACCGAGAA 
CTCCAGTTGG CTGGCTTTGA CCCCTCCCAG GATTCTCTAG GGCCCGGGAA CAATGACAGC 
ACCCTCAACA ACACAGCCAC ACTGACAGTT GGGCTACAGG ACTGTGGGCG GGACTGCCAT 
GCCATTCGTA TCGCCACTGC CCTCACTCTG ATGGCCGGGC TTTATCAGGT CCTCATGGGG 
ATCCTCCGGC TGGGCTTCGT GTCTACCTAT CTCTCGCAAC CCCTGCTCGA TGGCTTTGCT 
ATGGGAGCTT CTGTGACCAT CTTGACTTCT CAGGCTAAAC ACCTGCTGGG CGTGCGGATC 
CCTCGGCACC AGGGCCTAGG CATGGTGATC CACACTTGGC TGAGCTTGCT GCAGAACGTG 
GGACAGGCTA ATCTGTGTGA TGTGGTCACC AGTGCCGTGT GCCTGGCAGT GCTGCTGACA 
GCTAAGGAAC TCTCGGATCG CTATCGACAC TATCTGAAAG TGCCAGTGCC CACAGAGCTA 
TTAGTTATTG TGGTGGCCAC GATTGCGTCC CATTTTGGAC AGCTCCATAC ACGGTTTGGC 
TCGAGTGTGG CCGGCAACAT TCCCACTGGT TTTGTGGCCC CACAGATACC AGACCCTAAG 
ATAATGTGGA GTGTGGCCCT GGATGCCATG TCCCTGGCCC TCGTGGGCTC AGCCTTCTCC 
ATCTCCTTGG CAGAAATGTT TGCACGTAGT CATGGCTACT CTGTCAGTGC CAACCAAGAG 
CTGCTAGCTG TGGGCTGTTG CAACGTGCTG CCTGCCTTCT TCCACTGTTT TGCCACTAGT 
GCTGCTCTGT CCAAAACTCT GGTGAAGATA GCCACTGGCT GCCAGACCCA GTTGTCCAGT 
GTGGTCAGTG CTGCTGTGGT GTTGCTGGTG CTGCTGGTGC TGGCGCCATT GTTTCACGAT 
CTGCAGCGGT GTGTGTTAGC TTGCATCATT GTCGTCAGCC TGAGGGGGGC GCTGCGCAAG 
GTGAAGGATC TCCCACAACT TTGGCGGCTA AGCCCTGCGG ACGCACTGGT CTGGGTGGCT 
ACTGCAGCGA CCTGTGTTCT AGTCAGCATC GAGGCTGGGC TATTAGCTGG GGTGTTCTTC 
TCACTGCTCA GCCTGGCAGG CCGCACGCAG CGTCCACGGG CTGCCCTTCT GGCTCGAATT 
GGAGACTCGA CCTTCTATGA GGATGCTGCT GAGTTTGAGG GCCTCCTGCC CCCGCCCGAG 
GTGCGAGTGT TCCGTTTCAC AGGTCCGCTC TACTATGCCA ACAAGGATTT CTTCCTTCGG 
TCACTCTACA GTCTGACAGG GCTGGATGCT GGGTACTCAG CCACCAGGAA GGATCGGGGC 
ACAGAGGTGG GTGTCAGTAA CAGAAGTCTT GTTGACCGCA AGGATCTGGG TTCAGTGAGC 
AGTGGGGATG GGCTGGTTGT ACCCCTGGCA TTTGGTTTCC ACACAGTGGT CATTGACTGT 
GCACCACTGC TGTTCCTGGA TGTGGCTGGC ATGGCCACAT TGAAGGACCT GCGCAAAAAC 
TACAGGGCCC TGGACATCAC CCTGCTTCTG GCTTGCTGCA GTCCCTCAGT GAGAGACACA 
CTGAGAAAAG GGGGCTTCCT TGGGGAAGAC CAGGGAACTG AAGAGGAGCT GCTGTTCCCC 
AGTGTACACA GCGCTGTGGA GACAGCATGT GCCCGCCGTG AGGAGCTGAT GGCTGCTGAC 
TCTGCCCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SLC26A Gene Family Participate in pH Regulation during Enamel Maturation.
PloS one10(12)e0144703(2015)
Yin K,Lei Y,Wen X,Lacruz RS,Soleimani M,Kurtz I,Snead ML,White SN,Paine ML

The liver and kidney expression of sulfate anion transporter sat-1 in rats exhibits male-dominant gender differences.
Pflugers Archiv : European journal of physiology457(6)1381-92(2009 Apr)
Brzica H,Breljak D,Krick W,Lovri? M,Burckhardt G,Burckhardt BC,Saboli? I

Localization of the sulfate/anion exchanger in the rat liver.
American journal of physiology. Gastrointestinal and liver physiology290(5)G1075-81(2006 May)
Quondamatteo F,Krick W,Hagos Y,Kr?ger MH,Neubauer-Saile K,Herken R,Ramadori G,Burckhardt G,Burckhardt BC

A dileucine motif targets the sulfate anion transporter sat-1 to the basolateral membrane in renal cell lines.
American journal of physiology. Cell physiology287(2)C365-72(2004 Aug)
Regeer RR,Markovich D

The mouse sulfate anion transporter gene Sat1 (Slc26a1): cloning, tissue distribution, gene structure, functional characterization, and transcriptional regulation thyroid hormone.
DNA and cell biology22(1)19-31(2003 Jan)
Lee A,Beck L,Markovich D