Pdcd4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pdcd4
Entrez Gene ID	64031
Full Name	programmed cell death 4
Synonyms	Dug
General protein information	Preferred Names programmed cell death 4 Names programmed cell death protein 4 death up-regulated gene protein death-upregulated
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q55
Summary	acts as an inhibitor of apoptosis; has similarity to eukaryotic translation initiation factor (eIF)4G [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017589648.1	XP_017445137.1	programmed cell death protein 4 isoform X1
XM_006231614.3	XP_006231676.1	programmed cell death protein 4 isoform X1
XM_006231615.3	XP_006231677.1	programmed cell death protein 4 isoform X1
NM_022265.2	NP_071601.2	programmed cell death protein 4
XM_006231616.3	XP_006231678.1	programmed cell death protein 4 isoform X1
XM_006231613.3	XP_006231675.1	programmed cell death protein 4 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PDCD4	XP_001143772.1
	PDCD4	XP_001086788.1
Canis lupus familiaris (dog)	PDCD4	XP_005637778.1
Bos taurus (cattle)	PDCD4	NP_001077116.1
Mus musculus (house mouse)	Pdcd4	NP_001161964.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000378	XP_310731.4
Rattus norvegicus (Norway rat)	Pdcd4	NP_071601.2
Gallus gallus (chicken)	PDCD4	NP_989635.1
Oryza sativa (rice)	Os08g0120500	NP_001060879.1
Xenopus tropicalis (tropical clawed frog)	pdcd4	NP_998871.1
Drosophila melanogaster (fruit fly)	Pdcd4	NP_001096977.1
Arabidopsis thaliana (thale cress)	AT4G24800	NP_001031708.1
Homo sapiens (human)	PDCD4	NP_055271.2
Danio rerio (zebrafish)	pdcd4b	NP_945329.1
Arabidopsis thaliana (thale cress)	AT5G63190	NP_568968.1

Gene Ontology
Bibliography

Related articles in PubMed

MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
Wang L, Ye N, Lian X, Peng F, Zhang H, Gong H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie981-8(2017 Dec)

Depletion of the mRNA translation initiation inhibitor, programmed cell death protein 4 (PDCD4), impairs L6 myotube formation.
Maeda N, Abdullahi A, Beatty B, Dhanani Z, Adegoke OAJ
Physiological reports5(17)(2017 Sep)

Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis.
Fu X, He Y, Wang X, Peng D, Chen X, Li X, Wang Q
Stem cell research & therapy8(1)187(2017 Aug)

The role of tumour suppressor PDCD4 in beta cell death in hypoxia.
Kumar S, Marriott CE, Alhasawi NF, Bone AJ, Macfarlane WM
PloS one12(7)e0181235(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

-induced expression of PDCD4 is associated with increased beta cell death.
Title: The role of tumour suppressor PDCD4 in beta cell death in hypoxia.

cardiac progenitor cell-derived exosomal miR-21 had an inhibiting role in the apoptosis pathway through downregulating PDCD4.
Title: Cardiac progenitor cell-derived exosomes prevent cardiomyocytes apoptosis through exosomal miR-21 by targeting PDCD4.

Findings revealed the role of miR-499-5p in protecting the cardiomyocytes against apoptosis induced by acute myocardial infarction (AMI) via its direct target PDCD4, which providing evidence for the miR-499-5p/PDCD4 pathway as a potential therapeutic target for patients with AMI.
Title: MiR-499-5p protects cardiomyocytes against ischaemic injury via anti-apoptosis by targeting PDCD4.

The apoptosis process enhanced by overexpression of SOX6 or PDCD4, was rescued by the cardiac-abundant miR-499 in rat cardiomyocytes.
Title: SOX6 and PDCD4 enhance cardiomyocyte apoptosis through LPS-induced miR-499 inhibition.

Ischemic postconditioning (IPC)-regulated miR-499 plays an important role in IPC-mediated cardiac protection against myocardial ischemia/reperfusion injury by targeting PDCD4.
Title: Ischemic Postconditioning-Regulated miR-499 Protects the Rat Heart Against Ischemia/Reperfusion Injury by Inhibiting Apoptosis through PDCD4.

The following Pdcd4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pdcd4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa05578	NM_022265.2 Latest version!	Rattus norvegicus programmed cell death 4 (Pdcd4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa05578	XM_006231614.3 Latest version!	Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa05578	XM_006231615.3 Latest version!	Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa05578	XM_017589648.1 Latest version!	Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa05578	XM_006231616.3 Latest version!	Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa05578	XM_006231613.3 Latest version!	Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pdcd4 ( NM_022265.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071601.2 Rattus norvegicus programmed cell death 4 (Pdcd4), mRNA.

Price & Availability↑

CloneID	ORa05578
Clone ID Related Accession (Same CDS sequence)	XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version	NM_022265.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	programmed cell death protein 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF239739.2. On Jul 22, 2002 this sequence version replaced NM_022265.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF239739.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071601.2
CDS	1..1410
Translation	MDVENEQILNVNPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASTINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEAVRSGVAVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDETAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGKRKDSVWGSGGGQQPVNHLVKEIDMLLKEYLLSGDMSEAEHCLKELEVPHFHHELVYEAIVMVLESTGESAFKMMLDLLKSLWKSSTITIDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY

Target ORF information:

RefSeq Version	NM_022265.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus programmed cell death 4 (Pdcd4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022265.2

ORF Insert Sequence:

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pdcd4 ( XM_017589648.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017445137.1 Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa05578
Clone ID Related Accession (Same CDS sequence)	XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version	XM_017589648.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	programmed cell death protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017445137.1
CDS	88..1497
Translation	MDVENEQILNVNPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASTINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEAVRSGVAVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDETAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGKRKDSVWGSGGGQQPVNHLVKEIDMLLKEYLLSGDMSEAEHCLKELEVPHFHHELVYEAIVMVLESTGESAFKMMLDLLKSLWKSSTITIDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY

Target ORF information:

RefSeq Version	XM_017589648.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589648.1

ORF Insert Sequence:

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pdcd4 ( XM_006231614.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231676.1 Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa05578
Clone ID Related Accession (Same CDS sequence)	XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version	XM_006231614.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	programmed cell death protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231614.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231676.1
CDS	333..1742
Translation	MDVENEQILNVNPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASTINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEAVRSGVAVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDETAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGKRKDSVWGSGGGQQPVNHLVKEIDMLLKEYLLSGDMSEAEHCLKELEVPHFHHELVYEAIVMVLESTGESAFKMMLDLLKSLWKSSTITIDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY

Target ORF information:

RefSeq Version	XM_006231614.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231614.3

ORF Insert Sequence:

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pdcd4 ( XM_006231615.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231677.1 Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa05578
Clone ID Related Accession (Same CDS sequence)	XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version	XM_006231615.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	programmed cell death protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231615.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231677.1
CDS	173..1582
Translation	MDVENEQILNVNPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASTINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEAVRSGVAVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDETAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGKRKDSVWGSGGGQQPVNHLVKEIDMLLKEYLLSGDMSEAEHCLKELEVPHFHHELVYEAIVMVLESTGESAFKMMLDLLKSLWKSSTITIDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY

Target ORF information:

RefSeq Version	XM_006231615.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231615.3

ORF Insert Sequence:

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pdcd4 ( XM_006231616.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231678.1 Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa05578
Clone ID Related Accession (Same CDS sequence)	XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version	XM_006231616.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	programmed cell death protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231616.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231678.1
CDS	156..1565
Translation	MDVENEQILNVNPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASTINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEAVRSGVAVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDETAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGKRKDSVWGSGGGQQPVNHLVKEIDMLLKEYLLSGDMSEAEHCLKELEVPHFHHELVYEAIVMVLESTGESAFKMMLDLLKSLWKSSTITIDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY

Target ORF information:

RefSeq Version	XM_006231616.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231616.3

ORF Insert Sequence:

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pdcd4 ( XM_006231613.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231675.1 Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa05578
Clone ID Related Accession (Same CDS sequence)	XM_017589648.1 , XM_006231614.3 , XM_006231615.3 , NM_022265.2 , XM_006231616.3 , XM_006231613.3
Accession Version	XM_006231613.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	programmed cell death protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231613.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231675.1
CDS	282..1691
Translation	MDVENEQILNVNPTDPDNLSDSLFSGDEENAGTEEIKNEINGNWISASTINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSEAVRSGVAVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDETAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTNDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGKRKDSVWGSGGGQQPVNHLVKEIDMLLKEYLLSGDMSEAEHCLKELEVPHFHHELVYEAIVMVLESTGESAFKMMLDLLKSLWKSSTITIDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY

Target ORF information:

RefSeq Version	XM_006231613.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus programmed cell death 4 (Pdcd4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231613.3

ORF Insert Sequence:

ATGGATGTAG AAAACGAGCA GATACTGAAT GTGAACCCCA CTGACCCTGA CAATTTAAGT 
GACTCTCTCT TTTCTGGAGA TGAAGAAAAT GCTGGCACTG AGGAAATAAA GAATGAAATA 
AATGGAAATT GGATCTCCGC ATCTACTATT AATGAAGCTA GAATTAATGC TAAAGCAAAA 
AGACGACTGC GGAAAAATTC ATCCCGGGAC TCTGGCCGAG GCGATTCAGT CAGTGATAAT 
GGAAGTGAAG CAGTTAGAAG TGGAGTAGCT GTGCCCACCA GTCCAAAAGG AAGGTTGCTA 
GATAGGCGGT CCAGATCTGG GAAAGGAAGG GGGCTGCCAA AGAAAGGTGG TGCAGGAGGC 
AAGGGTGTCT GGGGCACACC TGGACAGGTA TATGATGTGG AGGAGGTGGA TGTGAAAGAT 
CCAAACTATG ATGATGACCA GGAGAACTGT GTTTATGAGA CTGTGGTTCT GCCCCTGGAT 
GAGACGGCGT TTGAGAAGAC GTTAACACCC ATCATACAGG AGTACTTTGA GCACGGAGAT 
ACGAACGAAG TCGCGGAGAT GTTAAGGGAT TTGAACCTTG GGGAGATGAA GAGTGGTGTG 
CCCGTGTTGG CAGTGTCCTT AGCCTTGGAG GGGAAAGCCA GTCACCGGGA GATGACTTCC 
AAGCTGCTTT CTGACCTTTG CGGGACAGTG ATGAGCACAA ATGACGTGGA AAAGTCATTT 
GACAAGTTGT TGAAGGATCT CCCCGAGCTA GCCTTGGACA CTCCGAGAGC ACCACAGTTG 
GTGGGCCAGT TTATTGCTAG AGCTGTTGGA GATGGGATCT TGTGTAACAC CTACATCGAT 
AGCTACAAAG GCACTGTGGA CTGCGTCCAG GCCAGGGCTG CTTTGGACAA GGCTACTGTG 
CTCCTGAGTA TGTCTAAAGG TGGAAAGCGT AAGGATAGTG TGTGGGGATC CGGAGGAGGG 
CAGCAGCCTG TCAATCACCT TGTTAAAGAG ATCGATATGC TGCTTAAAGA GTATTTGCTC 
TCTGGAGATA TGTCTGAAGC TGAGCACTGC CTTAAGGAAC TGGAAGTACC GCATTTCCAC 
CACGAGCTGG TATATGAGGC CATTGTAATG GTTTTAGAGT CAACTGGAGA AAGTGCATTC 
AAGATGATGT TAGATTTATT AAAATCCTTG TGGAAGTCTT CTACTATTAC CATAGACCAA 
ATGAAAAGAG GTTATGAGAG AATTTATAAT GAAATTCCGG ATATTAATCT GGATGTCCCA 
CACTCATACT CTGTGCTTGA GAGATTTGTG GAGGAATGTT TTCAGGCTGG AATCATTTCC 
AAACAACTCC GAGATCTTTG TCCATCAAGG GGAAGAAAGC GTTTTGTAAG TGAAGGAGAT 
GGAGGTCGTC TTAAACCTGA GAGCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MiR-208a-3p aggravates autophagy through the PDCD4-ATG5 pathway in Ang II-induced H9c2 cardiomyoblasts.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie981-8(2017 Dec)
Wang L,Ye N,Lian X,Peng F,Zhang H,Gong H

Depletion of the mRNA translation initiation inhibitor, programmed cell death protein 4 (PDCD4), impairs L6 myotube formation.
Physiological reports5(17)(2017 Sep)
Maeda N,Abdullahi A,Beatty B,Dhanani Z,Adegoke OAJ

Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis.
Stem cell research & therapy8(1)187(2017 Aug)
Fu X,He Y,Wang X,Peng D,Chen X,Li X,Wang Q

The role of tumour suppressor PDCD4 in beta cell death in hypoxia.
PloS one12(7)e0181235(2017)
Kumar S,Marriott CE,Alhasawi NF,Bone AJ,Macfarlane WM

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Pdcd4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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