S1pr5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	S1pr5
Entrez Gene ID	60399
Full Name	sphingosine-1-phosphate receptor 5
Synonyms	Edg-8,Edg8
General protein information	Preferred Names sphingosine-1-phosphate receptor 5 Names sphingosine 1-phosphate receptor 5 NRG-1 S1P receptor 5 S1P receptor Edg-8 S1P5 endothelial differentiation G-protein-coupled receptor 8 endothelial differentiation, sphingolipid G-protein-coupled receptor, 8 nerve growth factor-regulated G-protein-coupled receptor 1 sphingosine 1-phosphate receptor Edg-8
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q13
Summary	G protein-coupled receptor for the lysolipid phosphoric acid mediator sphingosine 1-phosphate [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006242663.3	XP_006242725.1	sphingosine 1-phosphate receptor 5 isoform X1
XM_006242664.3	XP_006242726.1	sphingosine 1-phosphate receptor 5 isoform X1
NM_021775.2	NP_068543.2	sphingosine 1-phosphate receptor 5
XM_006242665.3	XP_006242727.1	sphingosine 1-phosphate receptor 5 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	S1PR5	XP_003316134.1
Bos taurus (cattle)	S1PR5	NP_001179404.1
	S1PR5	XP_001101585.2
Canis lupus familiaris (dog)	S1PR5	XP_005632952.1
Mus musculus (house mouse)	S1pr5	NP_444420.1
Danio rerio (zebrafish)	s1pr5b	NP_001073124.1
Homo sapiens (human)	S1PR5	NP_001159687.1
Rattus norvegicus (Norway rat)	S1pr5	NP_068543.2

Gene Ontology
Bibliography

Related articles in PubMed

Lysophospholipid receptor nomenclature review: IUPHAR Review 8.
Kihara Y, Maceyka M, Spiegel S, Chun J
British journal of pharmacology171(15)3575-94(2014 Aug)

Expression of a novel sphingosine 1-phosphate receptor motif protein gene in maturing rat testes.
Khalid AM, Asano A, Hosaka YZ, Ohyama K, Ohta M, Yamano Y
Bioscience, biotechnology, and biochemistry76(9)1769-73(2012)

Silencing S1P1 receptors regulates collagen-V reactive lymphocyte-mediated immunobiology in the transplanted lung.
Chiyo M, Iwata T, Webb TJ, Vasko MR, Thompson EL, Heidler KM, Cummings OW, Yoshida S, Fujisawa T, Brand DD, Wilkes DS
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons8(3)537-46(2008 Mar)

Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors.
Jolly PS, Bektas M, Watterson KR, Sankala H, Payne SG, Milstien S, Spiegel S
Blood105(12)4736-42(2005 Jun)

Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival.
Jaillard C, Harrison S, Stankoff B, Aigrot MS, Calver AR, Duddy G, Walsh FS, Pangalos MN, Arimura N, Kaibuchi K, Zalc B, Lubetzki C
The Journal of neuroscience : the official journal of the Society for Neuroscience25(6)1459-69(2005 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The LOC290876-encoded gene product (EDG-8) has distinct roles in the nucleus during the processes of spermatocyte maturation and spermatid production in meiosis.
Title: Expression of a novel sphingosine 1-phosphate receptor motif protein gene in maturing rat testes.

These data demonstrate novel roles of S1P(1R,) which include regulating emigration and modulating lymphocyte activation.
Title: Silencing S1P1 receptors regulates collagen-V reactive lymphocyte-mediated immunobiology in the transplanted lung.

SphK1 has a role in regulating degranulation and motility of rat mast cells by desensitizing S1P receptors
Title: Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors.

Edg8/S1P5 activation on oligodendroglial cells modulates two distinct functional pathways mediating either process retraction or cell survival and that these effects depend on the developmental stage of the cell.
Title: Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival.

Edg8 receptors are preferentially expressed in oligodendrocyte lineage cells including oligodendrocyte progenitor cells and immature oligodendrocytes in rat CNS, and may have important functions in oligodendrocytic maturation and myelination.
Title: Edg-8 receptors are preferentially expressed in oligodendrocyte lineage cells of the rat CNS.

The following S1pr5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S1pr5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa05229	NM_021775.2 Latest version!	Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa30924	XM_006242663.3 Latest version!	Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa30924	XM_006242664.3 Latest version!	Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa30924	XM_006242665.3 Latest version!	Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

S1pr5 ( NM_021775.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_068543.2 Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), mRNA.

Price & Availability↑

CloneID	ORa05229
Clone ID Related Accession (Same CDS sequence)	NM_021775.2
Accession Version	NM_021775.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	sphingosine 1-phosphate receptor 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF115249.1. On Jun 4, 2003 this sequence version replaced NM_021775.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF115249.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMN02642649 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTCCG GGCTACTGCG GCCAGCGCCG GTGAGCGAGG TCATCGTCCT TCACTACAAC 
TACACTGGCA AGCTCCGGGG AGCGCGCTAC CAGCCCGGTG CCGGCCTGCG TGCGGACGCC 
GCAGTGTGCT TGGCTGTGTG CGCTTTCATC GTGCTGGAGA ACCTGGCTGT GCTCTTGGTG 
CTGGGCCGCC ATCCTCGCTT CCATGCACCC ATGTTCCTGC TCCTGGGTAG TCTTACCTTG 
TCGGACCTGC TCGCTGGGGC GGCCTACGCC ACCAACATCC TGCTGTCCGG GCCGCTCACA 
TTGCGCCTGT CGCCTGCGCT CTGGTTTGCG CGCGAAGGGG GTGTCTTCGT GGCGCTCGCA 
GCGTCGGTGC TGAGCCTCCT GGCCATTGCT ATAGAGCGCC ACCTTACCAT GGCCCGTCGT 
GGACCCGCGC CTGCCGCCAG TCGCGCTCGC ACGCTGGCGA TGGCGGTGGC CGCCTGGGGC 
TTGTTGTTGA CGCTGGGGCT GCTGCCCGCG CTGGGCTGGA ACTGCTTGGG ACGCCTGGAA 
GCCTGCTCCA CCGTGTTGCC GGTGTACGCC AAGGCCTATG TGCTCTTCTG CGTGCTGGCC 
TTCCTGGGCA TCCTGGCTGC CATCTGTGCG CTCTATGCAA GGATTTACTG TCAGGTGCGG 
GCCAACGCGC GTCGCCTGCG GGCCGGTCCT GGGTCCCGTA GGGCCACGTC CTCCTCGCGA 
TCCCGGCACA CGCCACGGTC GTTGGCCCTG CTCCGCACGC TTAGCGTGGT GCTCCTGGCC 
TTCGTGGCCT GCTGGGGACC TCTATTTCTC TTGCTATTAC TGGATGTCGC GTGCCCAGCC 
CGCGCGTGTC CTGTGCTTCT GCAAGCCGAT CCCTTCCTGG GTCTAGCCAT GGCTAACTCG 
CTGCTGAATC CTATCATCTA CACCTTCACC AACCGAGACC TGCGCCACGC GCTCCTGAGG 
CTGCTCTGCT GTGGCCGCGG ACCCTGCAAC CAAGACTCCT CCAACAGTTT GCAGCGATCC 
CCAAGTGCTG TTGGGCCTTC CGGTGGAGGC CTGCGACGCT GCCTGCCACC AACCCTGGAT 
CGCAGCTCTA GCCCATCAGA ACACTCGTGT CCCCAGCGGG ACGGGATGGA CACCAGCTGC 
TCCACTGGCA GTCCCGGAGC AGCAACCGCC AACCGGACCC TGGTGCCTGA TGCTACAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068543.2
CDS	258..1460
Translation	MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAAVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYATNILLSGPLTLRLSPALWFAREGGVFVALAASVLSLLAIAIERHLTMARRGPAPAASRARTLAMAVAAWGLLLTLGLLPALGWNCLGRLEACSTVLPVYAKAYVLFCVLAFLGILAAICALYARIYCQVRANARRLRAGPGSRRATSSSRSRHTPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARACPVLLQADPFLGLAMANSLLNPIIYTFTNRDLRHALLRLLCCGRGPCNQDSSNSLQRSPSAVGPSGGGLRRCLPPTLDRSSSPSEHSCPQRDGMDTSCSTGSPGAATANRTLVPDATD

Target ORF information:

RefSeq Version	NM_021775.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021775.2

ORF Insert Sequence:

ATGGAGTCCG GGCTACTGCG GCCAGCGCCG GTGAGCGAGG TCATCGTCCT TCACTACAAC 
TACACTGGCA AGCTCCGGGG AGCGCGCTAC CAGCCCGGTG CCGGCCTGCG TGCGGACGCC 
GCAGTGTGCT TGGCTGTGTG CGCTTTCATC GTGCTGGAGA ACCTGGCTGT GCTCTTGGTG 
CTGGGCCGCC ATCCTCGCTT CCATGCACCC ATGTTCCTGC TCCTGGGTAG TCTTACCTTG 
TCGGACCTGC TCGCTGGGGC GGCCTACGCC ACCAACATCC TGCTGTCCGG GCCGCTCACA 
TTGCGCCTGT CGCCTGCGCT CTGGTTTGCG CGCGAAGGGG GTGTCTTCGT GGCGCTCGCA 
GCGTCGGTGC TGAGCCTCCT GGCCATTGCT ATAGAGCGCC ACCTTACCAT GGCCCGTCGT 
GGACCCGCGC CTGCCGCCAG TCGCGCTCGC ACGCTGGCGA TGGCGGTGGC CGCCTGGGGC 
TTGTTGTTGA CGCTGGGGCT GCTGCCCGCG CTGGGCTGGA ACTGCTTGGG ACGCCTGGAA 
GCCTGCTCCA CCGTGTTGCC GGTGTACGCC AAGGCCTATG TGCTCTTCTG CGTGCTGGCC 
TTCCTGGGCA TCCTGGCTGC CATCTGTGCG CTCTATGCAA GGATTTACTG TCAGGTGCGG 
GCCAACGCGC GTCGCCTGCG GGCCGGTCCT GGGTCCCGTA GGGCCACGTC CTCCTCGCGA 
TCCCGGCACA CGCCACGGTC GTTGGCCCTG CTCCGCACGC TTAGCGTGGT GCTCCTGGCC 
TTCGTGGCCT GCTGGGGACC TCTATTTCTC TTGCTATTAC TGGATGTCGC GTGCCCAGCC 
CGCGCGTGTC CTGTGCTTCT GCAAGCCGAT CCCTTCCTGG GTCTAGCCAT GGCTAACTCG 
CTGCTGAATC CTATCATCTA CACCTTCACC AACCGAGACC TGCGCCACGC GCTCCTGAGG 
CTGCTCTGCT GTGGCCGCGG ACCCTGCAAC CAAGACTCCT CCAACAGTTT GCAGCGATCC 
CCAAGTGCTG TTGGGCCTTC CGGTGGAGGC CTGCGACGCT GCCTGCCACC AACCCTGGAT 
CGCAGCTCTA GCCCATCAGA ACACTCGTGT CCCCAGCGGG ACGGGATGGA CACCAGCTGC 
TCCACTGGCA GTCCCGGAGC AGCAACCGCC AACCGGACCC TGGTGCCTGA TGCTACAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S1pr5 ( XM_006242663.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242725.1 Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa30924
Clone ID Related Accession (Same CDS sequence)	XM_006242663.3 , XM_006242664.3 , XM_006242665.3
Accession Version	XM_006242663.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	sphingosine 1-phosphate receptor 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242663.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTCCG GGCTACTGCG GCCAGCGCCG GTGAGCGAGG TCATCGTCCT TCACTACAAC 
TACACTGGCA AGCTCCGGGG AGCGCGCTAC CAGCCCGGTG CCGGCCTGCG TGCGGACGCC 
GCAGTGTGCT TGGCTGTGTG CGCTTTCATC GTGCTGGAGA ACCTGGCTGT GCTCTTGGTG 
CTGGGCCGCC ATCCTCGCTT CCATGCACCC ATGTTCCTGC TCCTGGGTAG TCTTACCTTG 
TCGGACCTGC TCGCTGGGGC GGCCTACGCC ACCAACATCC TGCTGTCCGG GCCGCTCACA 
TTGCGCCTGT CGCCTGCGCT CTGGTTTGCG CGCGAAGGGG GTGTCTTCGT GGCGCTCGCA 
GCGTCGGTGC TGAGCCTCCT GGCCATTGCT CTAGAGCGCC ACCTTACCAT GGCCCGTCGT 
GGACCCGCGC CTGCCGCCAG TCGCGCTCGC ACGCTGGCGA TGGCGGTGGC CGCCTGGGGC 
TTGTCGCTGC TGCTGGGGCT GCTGCCCGCG CTGGGCTGGA ACTGCTTGGG ACGCCTGGAA 
GCCTGCTCCA CCGTGCTGCC GCTCTACGCC AAGGCCTATG TGCTCTTCTG CGTGCTGGCC 
TTCCTGGGCA TCCTGGCTGC CATCTGTGCG CTCTATGCAA GGATTTACTG TCAGGTGCGG 
GCCAACGCGC GTCGCCTGCG GGCCGGTCCT GGGTCCCGTA GGGCCACGTC CTCCTCGCGA 
TCCCGGCACA CGCCACGGTC GTTGGCCCTG CTCCGCACGC TTAGCGTGGT GCTCCTGGCC 
TTCGTGGCCT GCTGGGGACC TCTATTTCTC TTGCTATTAC TGGATGTCGC GTGCCCAGCC 
CGCGCGTGTC CTGTGCTTCT GCAAGCCGAT CCCTTCCTGG GTCTAGCCAT GGCTAACTCG 
CTGCTGAATC CTATCATCTA CACCTTCACC AACCGAGACC TGCGCCACGC GCTCCTGAGG 
CTGCTCTGCT GTGGCCGCGG ACCCTGCAAC CAAGACTCCT CCAACAGTTT GCAGCGATCC 
CCAAGTGCTG TTGGGCCTTC CGGTGGAGGC CTGCGACGCT GCCTGCCACC AACCCTGGAT 
CGCAGCTCTA GCCCATCAGA ACACTCGTGT CCCCAGCGGG ACGGGATGGA CACCAGCTGC 
TCCACTGGCA GTCCCGGAGC AGCAACCGCC AACCGGACCC TGGTGCCTGA TGCTACAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242725.1
CDS	191..1393
Translation	MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAAVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYATNILLSGPLTLRLSPALWFAREGGVFVALAASVLSLLAIALERHLTMARRGPAPAASRARTLAMAVAAWGLSLLLGLLPALGWNCLGRLEACSTVLPLYAKAYVLFCVLAFLGILAAICALYARIYCQVRANARRLRAGPGSRRATSSSRSRHTPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARACPVLLQADPFLGLAMANSLLNPIIYTFTNRDLRHALLRLLCCGRGPCNQDSSNSLQRSPSAVGPSGGGLRRCLPPTLDRSSSPSEHSCPQRDGMDTSCSTGSPGAATANRTLVPDATD

Target ORF information:

RefSeq Version	XM_006242663.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242663.3

ORF Insert Sequence:

ATGGAGTCCG GGCTACTGCG GCCAGCGCCG GTGAGCGAGG TCATCGTCCT TCACTACAAC 
TACACTGGCA AGCTCCGGGG AGCGCGCTAC CAGCCCGGTG CCGGCCTGCG TGCGGACGCC 
GCAGTGTGCT TGGCTGTGTG CGCTTTCATC GTGCTGGAGA ACCTGGCTGT GCTCTTGGTG 
CTGGGCCGCC ATCCTCGCTT CCATGCACCC ATGTTCCTGC TCCTGGGTAG TCTTACCTTG 
TCGGACCTGC TCGCTGGGGC GGCCTACGCC ACCAACATCC TGCTGTCCGG GCCGCTCACA 
TTGCGCCTGT CGCCTGCGCT CTGGTTTGCG CGCGAAGGGG GTGTCTTCGT GGCGCTCGCA 
GCGTCGGTGC TGAGCCTCCT GGCCATTGCT CTAGAGCGCC ACCTTACCAT GGCCCGTCGT 
GGACCCGCGC CTGCCGCCAG TCGCGCTCGC ACGCTGGCGA TGGCGGTGGC CGCCTGGGGC 
TTGTCGCTGC TGCTGGGGCT GCTGCCCGCG CTGGGCTGGA ACTGCTTGGG ACGCCTGGAA 
GCCTGCTCCA CCGTGCTGCC GCTCTACGCC AAGGCCTATG TGCTCTTCTG CGTGCTGGCC 
TTCCTGGGCA TCCTGGCTGC CATCTGTGCG CTCTATGCAA GGATTTACTG TCAGGTGCGG 
GCCAACGCGC GTCGCCTGCG GGCCGGTCCT GGGTCCCGTA GGGCCACGTC CTCCTCGCGA 
TCCCGGCACA CGCCACGGTC GTTGGCCCTG CTCCGCACGC TTAGCGTGGT GCTCCTGGCC 
TTCGTGGCCT GCTGGGGACC TCTATTTCTC TTGCTATTAC TGGATGTCGC GTGCCCAGCC 
CGCGCGTGTC CTGTGCTTCT GCAAGCCGAT CCCTTCCTGG GTCTAGCCAT GGCTAACTCG 
CTGCTGAATC CTATCATCTA CACCTTCACC AACCGAGACC TGCGCCACGC GCTCCTGAGG 
CTGCTCTGCT GTGGCCGCGG ACCCTGCAAC CAAGACTCCT CCAACAGTTT GCAGCGATCC 
CCAAGTGCTG TTGGGCCTTC CGGTGGAGGC CTGCGACGCT GCCTGCCACC AACCCTGGAT 
CGCAGCTCTA GCCCATCAGA ACACTCGTGT CCCCAGCGGG ACGGGATGGA CACCAGCTGC 
TCCACTGGCA GTCCCGGAGC AGCAACCGCC AACCGGACCC TGGTGCCTGA TGCTACAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S1pr5 ( XM_006242664.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242726.1 Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa30924
Clone ID Related Accession (Same CDS sequence)	XM_006242663.3 , XM_006242664.3 , XM_006242665.3
Accession Version	XM_006242664.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	sphingosine 1-phosphate receptor 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242664.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTCCG GGCTACTGCG GCCAGCGCCG GTGAGCGAGG TCATCGTCCT TCACTACAAC 
TACACTGGCA AGCTCCGGGG AGCGCGCTAC CAGCCCGGTG CCGGCCTGCG TGCGGACGCC 
GCAGTGTGCT TGGCTGTGTG CGCTTTCATC GTGCTGGAGA ACCTGGCTGT GCTCTTGGTG 
CTGGGCCGCC ATCCTCGCTT CCATGCACCC ATGTTCCTGC TCCTGGGTAG TCTTACCTTG 
TCGGACCTGC TCGCTGGGGC GGCCTACGCC ACCAACATCC TGCTGTCCGG GCCGCTCACA 
TTGCGCCTGT CGCCTGCGCT CTGGTTTGCG CGCGAAGGGG GTGTCTTCGT GGCGCTCGCA 
GCGTCGGTGC TGAGCCTCCT GGCCATTGCT CTAGAGCGCC ACCTTACCAT GGCCCGTCGT 
GGACCCGCGC CTGCCGCCAG TCGCGCTCGC ACGCTGGCGA TGGCGGTGGC CGCCTGGGGC 
TTGTCGCTGC TGCTGGGGCT GCTGCCCGCG CTGGGCTGGA ACTGCTTGGG ACGCCTGGAA 
GCCTGCTCCA CCGTGCTGCC GCTCTACGCC AAGGCCTATG TGCTCTTCTG CGTGCTGGCC 
TTCCTGGGCA TCCTGGCTGC CATCTGTGCG CTCTATGCAA GGATTTACTG TCAGGTGCGG 
GCCAACGCGC GTCGCCTGCG GGCCGGTCCT GGGTCCCGTA GGGCCACGTC CTCCTCGCGA 
TCCCGGCACA CGCCACGGTC GTTGGCCCTG CTCCGCACGC TTAGCGTGGT GCTCCTGGCC 
TTCGTGGCCT GCTGGGGACC TCTATTTCTC TTGCTATTAC TGGATGTCGC GTGCCCAGCC 
CGCGCGTGTC CTGTGCTTCT GCAAGCCGAT CCCTTCCTGG GTCTAGCCAT GGCTAACTCG 
CTGCTGAATC CTATCATCTA CACCTTCACC AACCGAGACC TGCGCCACGC GCTCCTGAGG 
CTGCTCTGCT GTGGCCGCGG ACCCTGCAAC CAAGACTCCT CCAACAGTTT GCAGCGATCC 
CCAAGTGCTG TTGGGCCTTC CGGTGGAGGC CTGCGACGCT GCCTGCCACC AACCCTGGAT 
CGCAGCTCTA GCCCATCAGA ACACTCGTGT CCCCAGCGGG ACGGGATGGA CACCAGCTGC 
TCCACTGGCA GTCCCGGAGC AGCAACCGCC AACCGGACCC TGGTGCCTGA TGCTACAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242726.1
CDS	1228..2430
Translation	MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAAVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYATNILLSGPLTLRLSPALWFAREGGVFVALAASVLSLLAIALERHLTMARRGPAPAASRARTLAMAVAAWGLSLLLGLLPALGWNCLGRLEACSTVLPLYAKAYVLFCVLAFLGILAAICALYARIYCQVRANARRLRAGPGSRRATSSSRSRHTPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARACPVLLQADPFLGLAMANSLLNPIIYTFTNRDLRHALLRLLCCGRGPCNQDSSNSLQRSPSAVGPSGGGLRRCLPPTLDRSSSPSEHSCPQRDGMDTSCSTGSPGAATANRTLVPDATD

Target ORF information:

RefSeq Version	XM_006242664.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242664.3

ORF Insert Sequence:

ATGGAGTCCG GGCTACTGCG GCCAGCGCCG GTGAGCGAGG TCATCGTCCT TCACTACAAC 
TACACTGGCA AGCTCCGGGG AGCGCGCTAC CAGCCCGGTG CCGGCCTGCG TGCGGACGCC 
GCAGTGTGCT TGGCTGTGTG CGCTTTCATC GTGCTGGAGA ACCTGGCTGT GCTCTTGGTG 
CTGGGCCGCC ATCCTCGCTT CCATGCACCC ATGTTCCTGC TCCTGGGTAG TCTTACCTTG 
TCGGACCTGC TCGCTGGGGC GGCCTACGCC ACCAACATCC TGCTGTCCGG GCCGCTCACA 
TTGCGCCTGT CGCCTGCGCT CTGGTTTGCG CGCGAAGGGG GTGTCTTCGT GGCGCTCGCA 
GCGTCGGTGC TGAGCCTCCT GGCCATTGCT CTAGAGCGCC ACCTTACCAT GGCCCGTCGT 
GGACCCGCGC CTGCCGCCAG TCGCGCTCGC ACGCTGGCGA TGGCGGTGGC CGCCTGGGGC 
TTGTCGCTGC TGCTGGGGCT GCTGCCCGCG CTGGGCTGGA ACTGCTTGGG ACGCCTGGAA 
GCCTGCTCCA CCGTGCTGCC GCTCTACGCC AAGGCCTATG TGCTCTTCTG CGTGCTGGCC 
TTCCTGGGCA TCCTGGCTGC CATCTGTGCG CTCTATGCAA GGATTTACTG TCAGGTGCGG 
GCCAACGCGC GTCGCCTGCG GGCCGGTCCT GGGTCCCGTA GGGCCACGTC CTCCTCGCGA 
TCCCGGCACA CGCCACGGTC GTTGGCCCTG CTCCGCACGC TTAGCGTGGT GCTCCTGGCC 
TTCGTGGCCT GCTGGGGACC TCTATTTCTC TTGCTATTAC TGGATGTCGC GTGCCCAGCC 
CGCGCGTGTC CTGTGCTTCT GCAAGCCGAT CCCTTCCTGG GTCTAGCCAT GGCTAACTCG 
CTGCTGAATC CTATCATCTA CACCTTCACC AACCGAGACC TGCGCCACGC GCTCCTGAGG 
CTGCTCTGCT GTGGCCGCGG ACCCTGCAAC CAAGACTCCT CCAACAGTTT GCAGCGATCC 
CCAAGTGCTG TTGGGCCTTC CGGTGGAGGC CTGCGACGCT GCCTGCCACC AACCCTGGAT 
CGCAGCTCTA GCCCATCAGA ACACTCGTGT CCCCAGCGGG ACGGGATGGA CACCAGCTGC 
TCCACTGGCA GTCCCGGAGC AGCAACCGCC AACCGGACCC TGGTGCCTGA TGCTACAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S1pr5 ( XM_006242665.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242727.1 Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), transcript variant X3, mRNA.

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CloneID	ORa30924
Clone ID Related Accession (Same CDS sequence)	XM_006242663.3 , XM_006242664.3 , XM_006242665.3
Accession Version	XM_006242665.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	sphingosine 1-phosphate receptor 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242665.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTCCG GGCTACTGCG GCCAGCGCCG GTGAGCGAGG TCATCGTCCT TCACTACAAC 
TACACTGGCA AGCTCCGGGG AGCGCGCTAC CAGCCCGGTG CCGGCCTGCG TGCGGACGCC 
GCAGTGTGCT TGGCTGTGTG CGCTTTCATC GTGCTGGAGA ACCTGGCTGT GCTCTTGGTG 
CTGGGCCGCC ATCCTCGCTT CCATGCACCC ATGTTCCTGC TCCTGGGTAG TCTTACCTTG 
TCGGACCTGC TCGCTGGGGC GGCCTACGCC ACCAACATCC TGCTGTCCGG GCCGCTCACA 
TTGCGCCTGT CGCCTGCGCT CTGGTTTGCG CGCGAAGGGG GTGTCTTCGT GGCGCTCGCA 
GCGTCGGTGC TGAGCCTCCT GGCCATTGCT CTAGAGCGCC ACCTTACCAT GGCCCGTCGT 
GGACCCGCGC CTGCCGCCAG TCGCGCTCGC ACGCTGGCGA TGGCGGTGGC CGCCTGGGGC 
TTGTCGCTGC TGCTGGGGCT GCTGCCCGCG CTGGGCTGGA ACTGCTTGGG ACGCCTGGAA 
GCCTGCTCCA CCGTGCTGCC GCTCTACGCC AAGGCCTATG TGCTCTTCTG CGTGCTGGCC 
TTCCTGGGCA TCCTGGCTGC CATCTGTGCG CTCTATGCAA GGATTTACTG TCAGGTGCGG 
GCCAACGCGC GTCGCCTGCG GGCCGGTCCT GGGTCCCGTA GGGCCACGTC CTCCTCGCGA 
TCCCGGCACA CGCCACGGTC GTTGGCCCTG CTCCGCACGC TTAGCGTGGT GCTCCTGGCC 
TTCGTGGCCT GCTGGGGACC TCTATTTCTC TTGCTATTAC TGGATGTCGC GTGCCCAGCC 
CGCGCGTGTC CTGTGCTTCT GCAAGCCGAT CCCTTCCTGG GTCTAGCCAT GGCTAACTCG 
CTGCTGAATC CTATCATCTA CACCTTCACC AACCGAGACC TGCGCCACGC GCTCCTGAGG 
CTGCTCTGCT GTGGCCGCGG ACCCTGCAAC CAAGACTCCT CCAACAGTTT GCAGCGATCC 
CCAAGTGCTG TTGGGCCTTC CGGTGGAGGC CTGCGACGCT GCCTGCCACC AACCCTGGAT 
CGCAGCTCTA GCCCATCAGA ACACTCGTGT CCCCAGCGGG ACGGGATGGA CACCAGCTGC 
TCCACTGGCA GTCCCGGAGC AGCAACCGCC AACCGGACCC TGGTGCCTGA TGCTACAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242727.1
CDS	823..2025
Translation	MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAAVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYATNILLSGPLTLRLSPALWFAREGGVFVALAASVLSLLAIALERHLTMARRGPAPAASRARTLAMAVAAWGLSLLLGLLPALGWNCLGRLEACSTVLPLYAKAYVLFCVLAFLGILAAICALYARIYCQVRANARRLRAGPGSRRATSSSRSRHTPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARACPVLLQADPFLGLAMANSLLNPIIYTFTNRDLRHALLRLLCCGRGPCNQDSSNSLQRSPSAVGPSGGGLRRCLPPTLDRSSSPSEHSCPQRDGMDTSCSTGSPGAATANRTLVPDATD

Target ORF information:

RefSeq Version	XM_006242665.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sphingosine-1-phosphate receptor 5 (S1pr5), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242665.3

ORF Insert Sequence:

ATGGAGTCCG GGCTACTGCG GCCAGCGCCG GTGAGCGAGG TCATCGTCCT TCACTACAAC 
TACACTGGCA AGCTCCGGGG AGCGCGCTAC CAGCCCGGTG CCGGCCTGCG TGCGGACGCC 
GCAGTGTGCT TGGCTGTGTG CGCTTTCATC GTGCTGGAGA ACCTGGCTGT GCTCTTGGTG 
CTGGGCCGCC ATCCTCGCTT CCATGCACCC ATGTTCCTGC TCCTGGGTAG TCTTACCTTG 
TCGGACCTGC TCGCTGGGGC GGCCTACGCC ACCAACATCC TGCTGTCCGG GCCGCTCACA 
TTGCGCCTGT CGCCTGCGCT CTGGTTTGCG CGCGAAGGGG GTGTCTTCGT GGCGCTCGCA 
GCGTCGGTGC TGAGCCTCCT GGCCATTGCT CTAGAGCGCC ACCTTACCAT GGCCCGTCGT 
GGACCCGCGC CTGCCGCCAG TCGCGCTCGC ACGCTGGCGA TGGCGGTGGC CGCCTGGGGC 
TTGTCGCTGC TGCTGGGGCT GCTGCCCGCG CTGGGCTGGA ACTGCTTGGG ACGCCTGGAA 
GCCTGCTCCA CCGTGCTGCC GCTCTACGCC AAGGCCTATG TGCTCTTCTG CGTGCTGGCC 
TTCCTGGGCA TCCTGGCTGC CATCTGTGCG CTCTATGCAA GGATTTACTG TCAGGTGCGG 
GCCAACGCGC GTCGCCTGCG GGCCGGTCCT GGGTCCCGTA GGGCCACGTC CTCCTCGCGA 
TCCCGGCACA CGCCACGGTC GTTGGCCCTG CTCCGCACGC TTAGCGTGGT GCTCCTGGCC 
TTCGTGGCCT GCTGGGGACC TCTATTTCTC TTGCTATTAC TGGATGTCGC GTGCCCAGCC 
CGCGCGTGTC CTGTGCTTCT GCAAGCCGAT CCCTTCCTGG GTCTAGCCAT GGCTAACTCG 
CTGCTGAATC CTATCATCTA CACCTTCACC AACCGAGACC TGCGCCACGC GCTCCTGAGG 
CTGCTCTGCT GTGGCCGCGG ACCCTGCAAC CAAGACTCCT CCAACAGTTT GCAGCGATCC 
CCAAGTGCTG TTGGGCCTTC CGGTGGAGGC CTGCGACGCT GCCTGCCACC AACCCTGGAT 
CGCAGCTCTA GCCCATCAGA ACACTCGTGT CCCCAGCGGG ACGGGATGGA CACCAGCTGC 
TCCACTGGCA GTCCCGGAGC AGCAACCGCC AACCGGACCC TGGTGCCTGA TGCTACAGAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lysophospholipid receptor nomenclature review: IUPHAR Review 8.
British journal of pharmacology171(15)3575-94(2014 Aug)
Kihara Y,Maceyka M,Spiegel S,Chun J

Expression of a novel sphingosine 1-phosphate receptor motif protein gene in maturing rat testes.
Bioscience, biotechnology, and biochemistry76(9)1769-73(2012)
Khalid AM,Asano A,Hosaka YZ,Ohyama K,Ohta M,Yamano Y

Silencing S1P1 receptors regulates collagen-V reactive lymphocyte-mediated immunobiology in the transplanted lung.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons8(3)537-46(2008 Mar)
Chiyo M,Iwata T,Webb TJ,Vasko MR,Thompson EL,Heidler KM,Cummings OW,Yoshida S,Fujisawa T,Brand DD,Wilkes DS

Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors.
Blood105(12)4736-42(2005 Jun)
Jolly PS,Bektas M,Watterson KR,Sankala H,Payne SG,Milstien S,Spiegel S

Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival.
The Journal of neuroscience : the official journal of the Society for Neuroscience25(6)1459-69(2005 Feb)
Jaillard C,Harrison S,Stankoff B,Aigrot MS,Calver AR,Duddy G,Walsh FS,Pangalos MN,Arimura N,Kaibuchi K,Zalc B,Lubetzki C

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S1pr5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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