Igbp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Igbp1
Entrez Gene ID	58845
Full Name	immunoglobulin binding protein 1
General protein information	Preferred Names immunoglobulin binding protein 1 Names immunoglobulin-binding protein 1 CD79a-binding protein 1 alpha4 phosphoprotein immunoglobulin (CD79A) binding protein 1 protein phosphatase 2/4/6 regulatory subunit
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq22
Summary	human homolog is a regulatory subunit of protein phosphatase 2-type phosphatases [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031624.3	NP_113812.1	immunoglobulin-binding protein 1

Pathways from BioSystems

Homologies

	LOC694663	XP_001083324.2
Bos taurus (cattle)	LOC534155	NP_001098458.1
Mus musculus (house mouse)	Igbp1	NP_032810.4
Rattus norvegicus (Norway rat)	Igbp1	NP_113812.1
Homo sapiens (human)	IGBP1	NP_001542.1
Xenopus tropicalis (tropical clawed frog)	igbp1	NP_001072440.1
Canis lupus familiaris (dog)	IGBP1	XP_005641500.1
Drosophila melanogaster (fruit fly)	Tap42	NP_723811.1
Bos taurus (cattle)	IGBP1	NP_001229513.1
Caenorhabditis elegans (roundworm)	ppfr-4	NP_497591.1
Danio rerio (zebrafish)	igbp1	NP_998687.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008797	XP_001237618.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression and regulation of type 2A protein phosphatases and alpha4 signalling in cardiac health and hypertrophy.
Eleftheriadou O, Boguslavskyi A, Longman MR, Cowan J, Francois A, Heads RJ, Wadzinski BE, Ryan A, Shattock MJ, Snabaitis AK
Basic research in cardiology112(4)37(2017 Jul)

Active transport of the ubiquitin ligase MID1 along the microtubules is regulated by protein phosphatase 2A.
Aranda-Orgill?s B, Aigner J, Kunath M, Lurz R, Schneider R, Schweiger S
PloS one3(10)e3507(2008)

Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.
Prickett TD, Brautigan DL
Molecular and cellular biology27(12)4217-27(2007 Jun)

Characterization of a novel, cytokine-inducible carboxypeptidase D isoform in haematopoietic tumour cells.
O'Malley PG, Sangster SM, Abdelmagid SA, Bearne SL, Too CK
The Biochemical journal390(Pt 3)665-73(2005 Sep)

The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis.
Kong M, Fox CJ, Mu J, Solt L, Xu A, Cinalli RM, Birnbaum MJ, Lindsten T, Thompson CB
Science (New York, N.Y.)306(5696)695-8(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Igbp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Igbp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08291	NM_031624.3 Latest version!	Rattus norvegicus immunoglobulin binding protein 1 (Igbp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Igbp1 ( NM_031624.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113812.1 Rattus norvegicus immunoglobulin binding protein 1 (Igbp1), mRNA.

Price & Availability↑

CloneID	ORa08291
Clone ID Related Accession (Same CDS sequence)	NM_031624.3
Accession Version	NM_031624.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	immunoglobulin-binding protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC068202.1. On Aug 31, 2012 this sequence version replaced NM_031624.2. ##Evidence-Data-START## Transcript exon combination :: BC068202.1, FQ222671.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGCGT CTGAAGAAGA GTTACTGCTG CCGCGGCTTC CGGAGCTCTT CGAAACCAGC 
AAGAAACTTC TGGAGGAGTT GGAAGTAGCA ACTGAACCCA CCGGCTCCCG AACAATCCAG 
GATAAGGTGT CCAAAGGACT AGAACTCCTT GAGAAGGCTG CCGGAATGTT ATCGCAGCTT 
GATTTGTTCA GCCGAAATGA AGATTTGGAA GAGATTGCTT CTATCGACCT GAAGTACCTG 
ATGGTACCAG CGTTGCAAGG AGCTCTCACC ATGAAACAAG TCAACCCCAG CAAGCGTCTA 
GATCATTTGC AGCGGGCTCG AGAACACTTC ATACATTTCT TAACTCAGTG TCATTGCTAT 
CATGTGGCAG AGTTTCAGCT ACCCCAAACC AAGAATAACT CAGCTGAAAA TAATACTGCT 
CGCTCCTCCA TGGCCTATCC AAATCTCGTT GCTATGGCAT CTCAAAGACA GGCTAAAATA 
GAGAGATACA AGCAGAAGAA GGAGGTGGAG CATAGGTTGT CTGCACTGAA ATCTGCTGTG 
GAAAGTGGTC AAGCAGATGA TGAGCGTGTT CGTGAATATT ACCTCCTTCA CCTTCGGAGG 
TGGATTGGTA TCAGCTTAGA AGAGATTGAG AGCATTGACC AGGAAATAAA GATCCTGAAA 
GACAAAGACT CTCCAAGAGA GGAATCAGCT TGTCAGTCAT CTCTTCCAGA GAAGCCTCCA 
ATGAAACCCT TCATCCTCAC TCGGAACAAG GCACAAGCCA AAGTATTTGG AACTGGTTAT 
CCCAGCCTGG CAACTATGAC GGTGAGTGAC TGGTATGAAC AGCATCAGAA GTACGGAGCC 
TTACCAGATC GGGGAATAGC CAAGCCGCCA TCAGCTGATT TTCAAAGAGC AGCTCAGCAG 
CAGGAAGATC AAGAGCAAAA GGATGAAGAG AATGAGGAGA AAGCCTTGCA CAGGATGCGA 
GAGTGGGATG ACTGGAAGGA CACGCATCCC AGGGGCTATG GCAACCGGCA GAACATGGGC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113812.1
CDS	13..1035
Translation	MAASEEELLLPRLPELFETSKKLLEELEVATEPTGSRTIQDKVSKGLELLEKAAGMLSQLDLFSRNEDLEEIASIDLKYLMVPALQGALTMKQVNPSKRLDHLQRAREHFIHFLTQCHCYHVAEFQLPQTKNNSAENNTARSSMAYPNLVAMASQRQAKIERYKQKKEVEHRLSALKSAVESGQADDERVREYYLLHLRRWIGISLEEIESIDQEIKILKDKDSPREESACQSSLPEKPPMKPFILTRNKAQAKVFGTGYPSLATMTVSDWYEQHQKYGALPDRGIAKPPSADFQRAAQQQEDQEQKDEENEEKALHRMREWDDWKDTHPRGYGNRQNMG

Target ORF information:

RefSeq Version	NM_031624.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus immunoglobulin binding protein 1 (Igbp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031624.3

ORF Insert Sequence:

ATGGCAGCGT CTGAAGAAGA GTTACTGCTG CCGCGGCTTC CGGAGCTCTT CGAAACCAGC 
AAGAAACTTC TGGAGGAGTT GGAAGTAGCA ACTGAACCCA CCGGCTCCCG AACAATCCAG 
GATAAGGTGT CCAAAGGACT AGAACTCCTT GAGAAGGCTG CCGGAATGTT ATCGCAGCTT 
GATTTGTTCA GCCGAAATGA AGATTTGGAA GAGATTGCTT CTATCGACCT GAAGTACCTG 
ATGGTACCAG CGTTGCAAGG AGCTCTCACC ATGAAACAAG TCAACCCCAG CAAGCGTCTA 
GATCATTTGC AGCGGGCTCG AGAACACTTC ATACATTTCT TAACTCAGTG TCATTGCTAT 
CATGTGGCAG AGTTTCAGCT ACCCCAAACC AAGAATAACT CAGCTGAAAA TAATACTGCT 
CGCTCCTCCA TGGCCTATCC AAATCTCGTT GCTATGGCAT CTCAAAGACA GGCTAAAATA 
GAGAGATACA AGCAGAAGAA GGAGGTGGAG CATAGGTTGT CTGCACTGAA ATCTGCTGTG 
GAAAGTGGTC AAGCAGATGA TGAGCGTGTT CGTGAATATT ACCTCCTTCA CCTTCGGAGG 
TGGATTGGTA TCAGCTTAGA AGAGATTGAG AGCATTGACC AGGAAATAAA GATCCTGAAA 
GACAAAGACT CTCCAAGAGA GGAATCAGCT TGTCAGTCAT CTCTTCCAGA GAAGCCTCCA 
ATGAAACCCT TCATCCTCAC TCGGAACAAG GCACAAGCCA AAGTATTTGG AACTGGTTAT 
CCCAGCCTGG CAACTATGAC GGTGAGTGAC TGGTATGAAC AGCATCAGAA GTACGGAGCC 
TTACCAGATC GGGGAATAGC CAAGCCGCCA TCAGCTGATT TTCAAAGAGC AGCTCAGCAG 
CAGGAAGATC AAGAGCAAAA GGATGAAGAG AATGAGGAGA AAGCCTTGCA CAGGATGCGA 
GAGTGGGATG ACTGGAAGGA CACGCATCCC AGGGGCTATG GCAACCGGCA GAACATGGGC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression and regulation of type 2A protein phosphatases and alpha4 signalling in cardiac health and hypertrophy.
Basic research in cardiology112(4)37(2017 Jul)
Eleftheriadou O,Boguslavskyi A,Longman MR,Cowan J,Francois A,Heads RJ,Wadzinski BE,Ryan A,Shattock MJ,Snabaitis AK

Active transport of the ubiquitin ligase MID1 along the microtubules is regulated by protein phosphatase 2A.
PloS one3(10)e3507(2008)
Aranda-Orgill?s B,Aigner J,Kunath M,Lurz R,Schneider R,Schweiger S

Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.
Molecular and cellular biology27(12)4217-27(2007 Jun)
Prickett TD,Brautigan DL

Characterization of a novel, cytokine-inducible carboxypeptidase D isoform in haematopoietic tumour cells.
The Biochemical journal390(Pt 3)665-73(2005 Sep)
O'Malley PG,Sangster SM,Abdelmagid SA,Bearne SL,Too CK

The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis.
Science (New York, N.Y.)306(5696)695-8(2004 Oct)
Kong M,Fox CJ,Mu J,Solt L,Xu A,Cinalli RM,Birnbaum MJ,Lindsten T,Thompson CB

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Igbp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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