Ednrb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ednrb
Entrez Gene ID	50672
Full Name	endothelin receptor type B
Synonyms	Ednra,Etb
General protein information	Preferred Names endothelin receptor type B Names endothelin receptor type B endothelin B receptor ET-B ET-BR endothelin receptor non-selective type
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15q22

mRNA and Protein(s)

mRNA	Protein	Name
XM_017599786.1	XP_017455275.1	endothelin B receptor isoform X1
NM_017333.1	NP_059029.1	endothelin receptor type B precursor
XM_006252431.3	XP_006252493.1	endothelin B receptor isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	EDNRB	XP_509693.1
Canis lupus familiaris (dog)	EDNRB	NP_001010943.2
Rattus norvegicus (Norway rat)	Ednrb	NP_059029.1
Homo sapiens (human)	EDNRB	NP_001188326.1
	EDNRB	XP_001089047.2
Danio rerio (zebrafish)	ednrb1a	NP_571272.1
Bos taurus (cattle)	EDNRB	NP_776734.1
Mus musculus (house mouse)	Ednrb	NP_001129533.1
Gallus gallus (chicken)	EDNRB	NP_001001127.1
Xenopus tropicalis (tropical clawed frog)	ednrb	NP_001072476.1

Gene Ontology
Bibliography

Related articles in PubMed

High glucose upregulates endothelin type B receptors in vascular smooth muscle cells via the downregulation of Sirt1.
Lin Y, Zhao Y, Liu E
International journal of molecular medicine41(1)439-445(2018 Jan)

Diurnal pattern in skin Na
Speed JS, Hyndman KA, Kasztan M, Johnston JG, Roth KJ, Titze JM, Pollock DM
American journal of physiology. Regulatory, integrative and comparative physiology(2017 Dec)

Endothelin receptor mediated Ca
Kristiansen SB, Haanes KA, Sheykhzade M, Edvinsson L
Journal of molecular and cellular cardiology1111-9(2017 Oct)

Renal denervation attenuates hypertension but not salt sensitivity in ET
Becker BK, Feagans AC, Chen D, Kasztan M, Jin C, Speed JS, Pollock JS, Pollock DM
American journal of physiology. Regulatory, integrative and comparative physiology313(4)R425-R437(2017 Oct)

Endothelin-1 Decreases Excitability of the Dorsal Root Ganglion Neurons via ET
Mule NK, Singh JN, Shah KU, Gulati A, Sharma SS
Molecular neurobiology(2017 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Denervation reduced mean arterial pressure in ETB-deficient rats compared with sham-operated controls, however denervation did not affect the increase in blood pressure after 2 wk of high-salt diet. Denervation reduced cardiac sympathetic-to-parasympathetic tone [low frequency-high frequency (LF/HF)] during normal salt diet and vasomotor LF/HF tone during high-salt diet in ETB-def rats.
Title: Renal denervation attenuates hypertension but not salt sensitivity in ET

Data analyses strongly suggest that the identified deletion in the intergenic region upstream of Ednrb, which might contain a melanocyte-specific enhancer, is the mutation causative of the head spot phenotype in the KFRS4/Kyo rat strain.
Title: A deletion in the intergenic region upstream of Ednrb causes head spot in the rat strain KFRS4/Kyo.

the mRNA expression of prepro-endothelin-1 (ppET-1), as well as that of the ETA and ETB receptors, were quantified by real-time PCR in these veins... exercise training mobilizes endothelin-1 (ET-1) to reinforce the Ang II-induced responses mainly through ETA activation
Title: Prostanoids counterbalance the synergism between endothelin-1 and angiotensin II in mesenteric veins of trained rats.

These findings demonstrate that diurnal excretion of an acute salt load 1) requires ET-1 and the ETB receptor, 2) is more evident in male vs. female rats, and 3) is opposed by the ETA receptor.
Title: Loss of endothelin B receptor function impairs sodium excretion in a time- and sex-dependent manner.

Expression of smooth muscle proteins and both ETA and ETB by the endovascular trophoblast enable it to contract upon activation of both receptors by ET1.
Title: Vasoactivity of the rat endovascular trophoblast.

The following Ednrb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ednrb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13159	NM_017333.1 Latest version!	Rattus norvegicus endothelin receptor type B (Ednrb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa13159	XM_017599786.1 Latest version!	Rattus norvegicus endothelin receptor type B (Ednrb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa13159	XM_006252431.3 Latest version!	Rattus norvegicus endothelin receptor type B (Ednrb), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ednrb ( NM_017333.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_059029.1 Rattus norvegicus endothelin receptor type B (Ednrb), mRNA.

Price & Availability↑

CloneID	ORa13159
Clone ID Related Accession (Same CDS sequence)	XM_017599786.1 , NM_017333.1 , XM_006252431.3
Accession Version	NM_017333.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	endothelin receptor type B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from S65355.1. On Dec 17, 2003 this sequence version replaced XM_344451.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: X57764.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCAATCGT CCGCAAGCCG GTGCGGACGC GCCTTGGTGG CGCTGCTGCT GGCCTGTGGC 
TTGTTGGGGG TATGGGGAGA GAAAAGAGGA TTCCCACCTG CCCAGGCCAC ACCATCTCTT 
CTCGGGACTA AAGAAGTTAT GACGCCACCC ACTAAGACCT CCTGGACTAG AGGTTCCAAC 
TCCAGTCTGA TGCGTTCCTC CGCACCTGCG GAGGTGACCA AAGGAGGGAG GGTGGCTGGA 
GTCCCGCCAA GATCCTTCCC TCCTCCGTGC CAACGAAAAA TTGAGATCAA CAAGACTTTT 
AAATACATCA ACACGATTGT ATCATGCCTC GTGTTCGTGC TAGGCATCAT CGGGAACTCC 
ACACTGCTAA GAATCATCTA CAAGAACAAG TGCATGAGAA ATGGTCCCAA TATCTTGATC 
GCCAGCCTGG CTCTGGGAGA TCTGCTACAC ATCATCATCG ACATTCCCAT TAATGCCTAC 
AAGCTGCTGG CAGGGGACTG GCCATTTGGA GCTGAGATGT GCAAGCTGGT GCCCTTCATA 
CAGAAGGCTT CTGTGGGGAT CACAGTGTTG AGTCTATGTG CTCTAAGTAT TGACAGATAT 
CGAGCTGTTG CTTCTTGGAG TCGAATTAAA GGAATTGGGG TTCCAAAATG GACAGCAGTA 
GAAATTGTTT TAATTTGGGT GGTCTCTGTG GTTCTGGCTG TCCCTGAAGC CATAGGTTTT 
GATGTGATTA CGTCGGACTA CAAAGGAAAG CCCCTAAGGG TCTGCATGCT TAATCCCTTT 
CAGAAAACAG CCTTCATGCA GTTTTACAAG ACAGCCAAAG ACTGGTGGCT GTTCAGTTTC 
TACTTCTGCT TGCCGCTAGC CATCACTGCG ATCTTTTACA CCCTAATGAC CTGTGAGATG 
CTCAGAAAGA AAAGTGGTAT GCAGATTGCC TTGAATGACC ACTTAAAGCA GAGACGAGAA 
GTGGCCAAGA CAGTATTCTG CCTGGTCCTC GTGTTTGCCC TCTGTTGGCT TCCCCTTCAC 
CTCAGCAGGA TTCTGAAGCT CACCCTTTAT GACCAGAGCA ATCCTCAGAG GTGTGAACTT 
CTGAGTTTTT TGCTGGTTTT GGACTACATT GGTATCAACA TGGCTTCTTT GAATTCCTGC 
ATTAATCCAA TCGCTCTGTA TTTGGTGAGC AAGAGATTCA AAAACTGCTT TAAGTCGTGT 
TTGTGCTGCT GGTGCCAAAC GTTTGAGGAA AAACAGTCCT TAGAGGAGAA GCAATCCTGC 
TTGAAGTTCA AAGCTAACGA TCACGGATAC GACAACTTCC GCTCCAGCAA TAAATACAGC 
TCATCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059029.1
CDS	252..1580
Translation	MQSSASRCGRALVALLLACGLLGVWGEKRGFPPAQATPSLLGTKEVMTPPTKTSWTRGSNSSLMRSSAPAEVTKGGRVAGVPPRSFPPPCQRKIEINKTFKYINTIVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINAYKLLAGDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDVITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAIFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPQRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS

Target ORF information:

RefSeq Version	NM_017333.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus endothelin receptor type B (Ednrb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017333.1

ORF Insert Sequence:

ATGCAATCGT CCGCAAGCCG GTGCGGACGC GCCTTGGTGG CGCTGCTGCT GGCCTGTGGC 
TTGTTGGGGG TATGGGGAGA GAAAAGAGGA TTCCCACCTG CCCAGGCCAC ACCATCTCTT 
CTCGGGACTA AAGAAGTTAT GACGCCACCC ACTAAGACCT CCTGGACTAG AGGTTCCAAC 
TCCAGTCTGA TGCGTTCCTC CGCACCTGCG GAGGTGACCA AAGGAGGGAG GGTGGCTGGA 
GTCCCGCCAA GATCCTTCCC TCCTCCGTGC CAACGAAAAA TTGAGATCAA CAAGACTTTT 
AAATACATCA ACACGATTGT ATCATGCCTC GTGTTCGTGC TAGGCATCAT CGGGAACTCC 
ACACTGCTAA GAATCATCTA CAAGAACAAG TGCATGAGAA ATGGTCCCAA TATCTTGATC 
GCCAGCCTGG CTCTGGGAGA TCTGCTACAC ATCATCATCG ACATTCCCAT TAATGCCTAC 
AAGCTGCTGG CAGGGGACTG GCCATTTGGA GCTGAGATGT GCAAGCTGGT GCCCTTCATA 
CAGAAGGCTT CTGTGGGGAT CACAGTGTTG AGTCTATGTG CTCTAAGTAT TGACAGATAT 
CGAGCTGTTG CTTCTTGGAG TCGAATTAAA GGAATTGGGG TTCCAAAATG GACAGCAGTA 
GAAATTGTTT TAATTTGGGT GGTCTCTGTG GTTCTGGCTG TCCCTGAAGC CATAGGTTTT 
GATGTGATTA CGTCGGACTA CAAAGGAAAG CCCCTAAGGG TCTGCATGCT TAATCCCTTT 
CAGAAAACAG CCTTCATGCA GTTTTACAAG ACAGCCAAAG ACTGGTGGCT GTTCAGTTTC 
TACTTCTGCT TGCCGCTAGC CATCACTGCG ATCTTTTACA CCCTAATGAC CTGTGAGATG 
CTCAGAAAGA AAAGTGGTAT GCAGATTGCC TTGAATGACC ACTTAAAGCA GAGACGAGAA 
GTGGCCAAGA CAGTATTCTG CCTGGTCCTC GTGTTTGCCC TCTGTTGGCT TCCCCTTCAC 
CTCAGCAGGA TTCTGAAGCT CACCCTTTAT GACCAGAGCA ATCCTCAGAG GTGTGAACTT 
CTGAGTTTTT TGCTGGTTTT GGACTACATT GGTATCAACA TGGCTTCTTT GAATTCCTGC 
ATTAATCCAA TCGCTCTGTA TTTGGTGAGC AAGAGATTCA AAAACTGCTT TAAGTCGTGT 
TTGTGCTGCT GGTGCCAAAC GTTTGAGGAA AAACAGTCCT TAGAGGAGAA GCAATCCTGC 
TTGAAGTTCA AAGCTAACGA TCACGGATAC GACAACTTCC GCTCCAGCAA TAAATACAGC 
TCATCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ednrb ( XM_017599786.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017455275.1 Rattus norvegicus endothelin receptor type B (Ednrb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa13159
Clone ID Related Accession (Same CDS sequence)	XM_017599786.1 , NM_017333.1 , XM_006252431.3
Accession Version	XM_017599786.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	endothelin B receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAATCGT CCGCAAGCCG GTGCGGACGC GCCTTGGTGG CGCTGCTGCT GGCCTGTGGC 
TTGTTGGGGG TATGGGGAGA GAAAAGAGGA TTCCCACCTG CCCAGGCCAC ACCATCTCTT 
CTCGGGACTA AAGAAGTTAT GACGCCACCC ACTAAGACCT CCTGGACTAG AGGTTCCAAC 
TCCAGTCTGA TGCGTTCCTC CGCACCTGCG GAGGTGACCA AAGGAGGGAG GGTGGCTGGA 
GTCCCGCCAA GATCCTTCCC TCCTCCGTGC CAACGAAAAA TTGAGATCAA CAAGACTTTT 
AAATACATCA ACACGATTGT ATCATGCCTC GTGTTCGTGC TAGGCATCAT CGGGAACTCC 
ACACTGCTAA GAATCATCTA CAAGAACAAG TGCATGAGAA ATGGTCCCAA TATCTTGATC 
GCCAGCCTGG CTCTGGGAGA TCTGCTACAC ATCATCATCG ACATTCCCAT TAATGCCTAC 
AAGCTGCTGG CAGGGGACTG GCCATTTGGA GCTGAGATGT GCAAGCTGGT GCCCTTCATA 
CAGAAGGCTT CTGTGGGGAT CACAGTGTTG AGTCTATGTG CTCTAAGTAT TGACAGATAT 
CGAGCTGTTG CTTCTTGGAG TCGAATTAAA GGAATTGGGG TTCCAAAATG GACAGCAGTA 
GAAATTGTTT TAATTTGGGT GGTCTCTGTG GTTCTGGCTG TCCCTGAAGC CATAGGTTTT 
GATGTGATTA CGTCGGACTA CAAAGGAAAG CCCCTAAGGG TCTGCATGCT TAATCCCTTT 
CAGAAAACAG CCTTCATGCA GTTTTACAAG ACAGCCAAAG ACTGGTGGCT GTTCAGTTTC 
TACTTCTGCT TGCCGCTAGC CATCACTGCG ATCTTTTACA CCCTAATGAC CTGTGAGATG 
CTCAGAAAGA AAAGTGGTAT GCAGATTGCC TTGAATGACC ACTTAAAGCA GAGACGAGAA 
GTGGCCAAGA CAGTATTCTG CCTGGTCCTC GTGTTTGCCC TCTGTTGGCT TCCCCTTCAC 
CTCAGCAGGA TTCTGAAGCT CACCCTTTAT GACCAGAGCA ATCCTCAGAG GTGTGAACTT 
CTGAGTTTTT TGCTGGTTTT GGACTACATT GGTATCAACA TGGCTTCTTT GAATTCCTGC 
ATTAATCCAA TCGCTCTGTA TTTGGTGAGC AAGAGATTCA AAAACTGCTT TAAGTCGTGT 
TTGTGCTGCT GGTGCCAAAC GTTTGAGGAA AAACAGTCCT TAGAGGAGAA GCAATCCTGC 
TTGAAGTTCA AAGCTAACGA TCACGGATAC GACAACTTCC GCTCCAGCAA TAAATACAGC 
TCATCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017455275.1
CDS	592..1920
Translation	MQSSASRCGRALVALLLACGLLGVWGEKRGFPPAQATPSLLGTKEVMTPPTKTSWTRGSNSSLMRSSAPAEVTKGGRVAGVPPRSFPPPCQRKIEINKTFKYINTIVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINAYKLLAGDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDVITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAIFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPQRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS

Target ORF information:

RefSeq Version	XM_017599786.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus endothelin receptor type B (Ednrb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599786.1

ORF Insert Sequence:

ATGCAATCGT CCGCAAGCCG GTGCGGACGC GCCTTGGTGG CGCTGCTGCT GGCCTGTGGC 
TTGTTGGGGG TATGGGGAGA GAAAAGAGGA TTCCCACCTG CCCAGGCCAC ACCATCTCTT 
CTCGGGACTA AAGAAGTTAT GACGCCACCC ACTAAGACCT CCTGGACTAG AGGTTCCAAC 
TCCAGTCTGA TGCGTTCCTC CGCACCTGCG GAGGTGACCA AAGGAGGGAG GGTGGCTGGA 
GTCCCGCCAA GATCCTTCCC TCCTCCGTGC CAACGAAAAA TTGAGATCAA CAAGACTTTT 
AAATACATCA ACACGATTGT ATCATGCCTC GTGTTCGTGC TAGGCATCAT CGGGAACTCC 
ACACTGCTAA GAATCATCTA CAAGAACAAG TGCATGAGAA ATGGTCCCAA TATCTTGATC 
GCCAGCCTGG CTCTGGGAGA TCTGCTACAC ATCATCATCG ACATTCCCAT TAATGCCTAC 
AAGCTGCTGG CAGGGGACTG GCCATTTGGA GCTGAGATGT GCAAGCTGGT GCCCTTCATA 
CAGAAGGCTT CTGTGGGGAT CACAGTGTTG AGTCTATGTG CTCTAAGTAT TGACAGATAT 
CGAGCTGTTG CTTCTTGGAG TCGAATTAAA GGAATTGGGG TTCCAAAATG GACAGCAGTA 
GAAATTGTTT TAATTTGGGT GGTCTCTGTG GTTCTGGCTG TCCCTGAAGC CATAGGTTTT 
GATGTGATTA CGTCGGACTA CAAAGGAAAG CCCCTAAGGG TCTGCATGCT TAATCCCTTT 
CAGAAAACAG CCTTCATGCA GTTTTACAAG ACAGCCAAAG ACTGGTGGCT GTTCAGTTTC 
TACTTCTGCT TGCCGCTAGC CATCACTGCG ATCTTTTACA CCCTAATGAC CTGTGAGATG 
CTCAGAAAGA AAAGTGGTAT GCAGATTGCC TTGAATGACC ACTTAAAGCA GAGACGAGAA 
GTGGCCAAGA CAGTATTCTG CCTGGTCCTC GTGTTTGCCC TCTGTTGGCT TCCCCTTCAC 
CTCAGCAGGA TTCTGAAGCT CACCCTTTAT GACCAGAGCA ATCCTCAGAG GTGTGAACTT 
CTGAGTTTTT TGCTGGTTTT GGACTACATT GGTATCAACA TGGCTTCTTT GAATTCCTGC 
ATTAATCCAA TCGCTCTGTA TTTGGTGAGC AAGAGATTCA AAAACTGCTT TAAGTCGTGT 
TTGTGCTGCT GGTGCCAAAC GTTTGAGGAA AAACAGTCCT TAGAGGAGAA GCAATCCTGC 
TTGAAGTTCA AAGCTAACGA TCACGGATAC GACAACTTCC GCTCCAGCAA TAAATACAGC 
TCATCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ednrb ( XM_006252431.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252493.1 Rattus norvegicus endothelin receptor type B (Ednrb), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa13159
Clone ID Related Accession (Same CDS sequence)	XM_017599786.1 , NM_017333.1 , XM_006252431.3
Accession Version	XM_006252431.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	endothelin B receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252431.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAATCGT CCGCAAGCCG GTGCGGACGC GCCTTGGTGG CGCTGCTGCT GGCCTGTGGC 
TTGTTGGGGG TATGGGGAGA GAAAAGAGGA TTCCCACCTG CCCAGGCCAC ACCATCTCTT 
CTCGGGACTA AAGAAGTTAT GACGCCACCC ACTAAGACCT CCTGGACTAG AGGTTCCAAC 
TCCAGTCTGA TGCGTTCCTC CGCACCTGCG GAGGTGACCA AAGGAGGGAG GGTGGCTGGA 
GTCCCGCCAA GATCCTTCCC TCCTCCGTGC CAACGAAAAA TTGAGATCAA CAAGACTTTT 
AAATACATCA ACACGATTGT ATCATGCCTC GTGTTCGTGC TAGGCATCAT CGGGAACTCC 
ACACTGCTAA GAATCATCTA CAAGAACAAG TGCATGAGAA ATGGTCCCAA TATCTTGATC 
GCCAGCCTGG CTCTGGGAGA TCTGCTACAC ATCATCATCG ACATTCCCAT TAATGCCTAC 
AAGCTGCTGG CAGGGGACTG GCCATTTGGA GCTGAGATGT GCAAGCTGGT GCCCTTCATA 
CAGAAGGCTT CTGTGGGGAT CACAGTGTTG AGTCTATGTG CTCTAAGTAT TGACAGATAT 
CGAGCTGTTG CTTCTTGGAG TCGAATTAAA GGAATTGGGG TTCCAAAATG GACAGCAGTA 
GAAATTGTTT TAATTTGGGT GGTCTCTGTG GTTCTGGCTG TCCCTGAAGC CATAGGTTTT 
GATGTGATTA CGTCGGACTA CAAAGGAAAG CCCCTAAGGG TCTGCATGCT TAATCCCTTT 
CAGAAAACAG CCTTCATGCA GTTTTACAAG ACAGCCAAAG ACTGGTGGCT GTTCAGTTTC 
TACTTCTGCT TGCCGCTAGC CATCACTGCG ATCTTTTACA CCCTAATGAC CTGTGAGATG 
CTCAGAAAGA AAAGTGGTAT GCAGATTGCC TTGAATGACC ACTTAAAGCA GAGACGAGAA 
GTGGCCAAGA CAGTATTCTG CCTGGTCCTC GTGTTTGCCC TCTGTTGGCT TCCCCTTCAC 
CTCAGCAGGA TTCTGAAGCT CACCCTTTAT GACCAGAGCA ATCCTCAGAG GTGTGAACTT 
CTGAGTTTTT TGCTGGTTTT GGACTACATT GGTATCAACA TGGCTTCTTT GAATTCCTGC 
ATTAATCCAA TCGCTCTGTA TTTGGTGAGC AAGAGATTCA AAAACTGCTT TAAGTCGTGT 
TTGTGCTGCT GGTGCCAAAC GTTTGAGGAA AAACAGTCCT TAGAGGAGAA GCAATCCTGC 
TTGAAGTTCA AAGCTAACGA TCACGGATAC GACAACTTCC GCTCCAGCAA TAAATACAGC 
TCATCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252493.1
CDS	520..1848
Translation	MQSSASRCGRALVALLLACGLLGVWGEKRGFPPAQATPSLLGTKEVMTPPTKTSWTRGSNSSLMRSSAPAEVTKGGRVAGVPPRSFPPPCQRKIEINKTFKYINTIVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINAYKLLAGDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDVITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAIFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPQRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS

Target ORF information:

RefSeq Version	XM_006252431.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus endothelin receptor type B (Ednrb), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252431.3

ORF Insert Sequence:

ATGCAATCGT CCGCAAGCCG GTGCGGACGC GCCTTGGTGG CGCTGCTGCT GGCCTGTGGC 
TTGTTGGGGG TATGGGGAGA GAAAAGAGGA TTCCCACCTG CCCAGGCCAC ACCATCTCTT 
CTCGGGACTA AAGAAGTTAT GACGCCACCC ACTAAGACCT CCTGGACTAG AGGTTCCAAC 
TCCAGTCTGA TGCGTTCCTC CGCACCTGCG GAGGTGACCA AAGGAGGGAG GGTGGCTGGA 
GTCCCGCCAA GATCCTTCCC TCCTCCGTGC CAACGAAAAA TTGAGATCAA CAAGACTTTT 
AAATACATCA ACACGATTGT ATCATGCCTC GTGTTCGTGC TAGGCATCAT CGGGAACTCC 
ACACTGCTAA GAATCATCTA CAAGAACAAG TGCATGAGAA ATGGTCCCAA TATCTTGATC 
GCCAGCCTGG CTCTGGGAGA TCTGCTACAC ATCATCATCG ACATTCCCAT TAATGCCTAC 
AAGCTGCTGG CAGGGGACTG GCCATTTGGA GCTGAGATGT GCAAGCTGGT GCCCTTCATA 
CAGAAGGCTT CTGTGGGGAT CACAGTGTTG AGTCTATGTG CTCTAAGTAT TGACAGATAT 
CGAGCTGTTG CTTCTTGGAG TCGAATTAAA GGAATTGGGG TTCCAAAATG GACAGCAGTA 
GAAATTGTTT TAATTTGGGT GGTCTCTGTG GTTCTGGCTG TCCCTGAAGC CATAGGTTTT 
GATGTGATTA CGTCGGACTA CAAAGGAAAG CCCCTAAGGG TCTGCATGCT TAATCCCTTT 
CAGAAAACAG CCTTCATGCA GTTTTACAAG ACAGCCAAAG ACTGGTGGCT GTTCAGTTTC 
TACTTCTGCT TGCCGCTAGC CATCACTGCG ATCTTTTACA CCCTAATGAC CTGTGAGATG 
CTCAGAAAGA AAAGTGGTAT GCAGATTGCC TTGAATGACC ACTTAAAGCA GAGACGAGAA 
GTGGCCAAGA CAGTATTCTG CCTGGTCCTC GTGTTTGCCC TCTGTTGGCT TCCCCTTCAC 
CTCAGCAGGA TTCTGAAGCT CACCCTTTAT GACCAGAGCA ATCCTCAGAG GTGTGAACTT 
CTGAGTTTTT TGCTGGTTTT GGACTACATT GGTATCAACA TGGCTTCTTT GAATTCCTGC 
ATTAATCCAA TCGCTCTGTA TTTGGTGAGC AAGAGATTCA AAAACTGCTT TAAGTCGTGT 
TTGTGCTGCT GGTGCCAAAC GTTTGAGGAA AAACAGTCCT TAGAGGAGAA GCAATCCTGC 
TTGAAGTTCA AAGCTAACGA TCACGGATAC GACAACTTCC GCTCCAGCAA TAAATACAGC 
TCATCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High glucose upregulates endothelin type B receptors in vascular smooth muscle cells via the downregulation of Sirt1.
International journal of molecular medicine41(1)439-445(2018 Jan)
Lin Y,Zhao Y,Liu E

Diurnal pattern in skin Na
American journal of physiology. Regulatory, integrative and comparative physiology(2017 Dec)
Speed JS,Hyndman KA,Kasztan M,Johnston JG,Roth KJ,Titze JM,Pollock DM

Endothelin receptor mediated Ca
Journal of molecular and cellular cardiology1111-9(2017 Oct)
Kristiansen SB,Haanes KA,Sheykhzade M,Edvinsson L

Renal denervation attenuates hypertension but not salt sensitivity in ET
American journal of physiology. Regulatory, integrative and comparative physiology313(4)R425-R437(2017 Oct)
Becker BK,Feagans AC,Chen D,Kasztan M,Jin C,Speed JS,Pollock JS,Pollock DM

Endothelin-1 Decreases Excitability of the Dorsal Root Ganglion Neurons via ET
Molecular neurobiology(2017 Jun)
Mule NK,Singh JN,Shah KU,Gulati A,Sharma SS

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Ednrb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報