Ubl5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ubl5
Entrez Gene ID	500954
Full Name	ubiquitin-like 5
Synonyms	beacon
General protein information	Preferred Names ubiquitin-like 5 Names ubiquitin-like protein 5 ubiquitin-like 5 protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q13

mRNA and Protein(s)

mRNA	Protein	Name
XM_006242661.3	XP_006242723.1	ubiquitin-like protein 5 isoform X1
NM_001048243.2	NP_001041708.2	ubiquitin-like protein 5

Pathways from BioSystems

Homologies

Bos taurus (cattle)	UBL5	NP_001032799.1
Danio rerio (zebrafish)	zgc:66388	NP_957435.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011251	XP_309393.2
Saccharomyces cerevisiae (baker's yeast)	HUB1	NP_014430.1
Xenopus tropicalis (tropical clawed frog)	ubl5	NP_001119591.1
Homo sapiens (human)	UBL5	NP_001041706.1
Canis lupus familiaris (dog)	UBL5	XP_854056.1
Kluyveromyces lactis	KLLA0C08470g	XP_452578.1
Pan troglodytes (chimpanzee)	UBL5	XP_512356.2
Rattus norvegicus (Norway rat)	Ubl5	NP_001041708.2
Schizosaccharomyces pombe (fission yeast)	hub1	NP_595099.1
Oryza sativa (rice)	Os12g0143150	NP_001176788.1
Drosophila melanogaster (fruit fly)	ubl	NP_610239.1
	UBL5	XP_002801110.1
Mus musculus (house mouse)	Ubl5	NP_079677.1
Caenorhabditis elegans (roundworm)	ubl-5	NP_491640.1
Arabidopsis thaliana (thale cress)	AT3G45180	NP_190104.1

Gene Ontology
Bibliography

Related articles in PubMed

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Hasson SA, Kane LA, Yamano K, Huang CH, Sliter DA, Buehler E, Wang C, Heman-Ackah SM, Hessa T, Guha R, Martin SE, Youle RJ
Nature504(7479)291-5(2013 Dec)

Down-regulation of the beacon gene expression in the regenerating rat adrenal cortex.
Ziolkowska A, Rucinski M, Tyczewska M, Belloni AS, Nowak M, Nussdorfer GG, Malendowicz LK
Peptides27(12)3216-9(2006 Dec)

Distribution of beacon immunoreactivity in the rat brain.
Wang F, Tian DR, Tian N, Chen H, Shi YS, Chang JK, Yang J, Yuan L, Han JS
Peptides27(1)165-71(2006 Jan)

Differential expression and function of beacon in the rat adrenal cortex and medulla.
Rucinski M, Andreis PG, Ziolkowska A, Nussdorfer GG, Malendowicz LK
International journal of molecular medicine16(1)35-40(2005 Jul)

Isolation of a ubiquitin-like (UBL5) gene from a screen identifying highly expressed and conserved iris genes.
Friedman JS, Koop BF, Raymond V, Walter MA
Genomics71(2)252-5(2001 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a hypothalamic peptide involved in the regulation of food intake which might act as an endogenous inhibitor of adrenocortical growth in the rat.
Title: Down-regulation of the beacon gene expression in the regenerating rat adrenal cortex.

The topographical distribution of beacon immunoreactivity in rat brain indicates its possible function as a neutrotransmitter, a neuromodulator, or a neuroendocrine regulator, depending upon its localization.
Title: Distribution of beacon immunoreactivity in the rat brain.

The hypothesis is advanced that beacon is to be considered an autocrine-paracrine negative regulator of mineralo- and glucocorticoid synthesis in the rat adrenal gland.
Title: Differential expression and function of beacon in the rat adrenal cortex and medulla.

The following Ubl5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ubl5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10302	NM_001048243.2 Latest version!	Rattus norvegicus ubiquitin-like 5 (Ubl5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa10302	XM_006242661.3 Latest version!	Rattus norvegicus ubiquitin-like 5 (Ubl5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ubl5 ( NM_001048243.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001041708.2 Rattus norvegicus ubiquitin-like 5 (Ubl5), mRNA.

Price & Availability↑

CloneID	ORa10302
Clone ID Related Accession (Same CDS sequence)	XM_006242661.3 , NM_001048243.2
Accession Version	NM_001048243.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 222bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	ubiquitin-like protein 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CB713235.1. On Sep 30, 2006 this sequence version replaced NM_001048243.1. ##Evidence-Data-START## Transcript exon combination :: CB713235.1, FM052673.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGATTGAGG TGGTTTGCAA CGACCGTCTA GGAAAGAAAG TCCGCGTTAA GTGCAACACC 
GATGACACCA TCGGCGACCT GAAGAAACTG ATAGCGGCTC AAACTGGCAC CCGCTGGAAT 
AAGATCGTTC TTAAAAAGTG GTACACGATT TTTAAAGACC ACGTGTCTCT GGGAGACTAT 
GAGATCCACG ACGGGATGAA CCTGGAGCTT TATTACCAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001041708.2
CDS	120..341
Translation	MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKWYTIFKDHVSLGDYEIHDGMNLELYYQ

Target ORF information:

RefSeq Version	NM_001048243.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ubiquitin-like 5 (Ubl5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001048243.2

ORF Insert Sequence:

ATGATTGAGG TGGTTTGCAA CGACCGTCTA GGAAAGAAAG TCCGCGTTAA GTGCAACACC 
GATGACACCA TCGGCGACCT GAAGAAACTG ATAGCGGCTC AAACTGGCAC CCGCTGGAAT 
AAGATCGTTC TTAAAAAGTG GTACACGATT TTTAAAGACC ACGTGTCTCT GGGAGACTAT 
GAGATCCACG ACGGGATGAA CCTGGAGCTT TATTACCAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ubl5 ( XM_006242661.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242723.1 Rattus norvegicus ubiquitin-like 5 (Ubl5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa10302
Clone ID Related Accession (Same CDS sequence)	XM_006242661.3 , NM_001048243.2
Accession Version	XM_006242661.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 222bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ubiquitin-like protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242661.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTGAGG TGGTTTGCAA CGACCGTCTA GGAAAGAAAG TCCGCGTTAA GTGCAACACC 
GATGACACCA TCGGCGACCT GAAGAAACTG ATAGCGGCTC AAACTGGCAC CCGCTGGAAT 
AAGATCGTTC TTAAAAAGTG GTACACGATT TTTAAAGACC ACGTGTCTCT GGGAGACTAT 
GAGATCCACG ACGGGATGAA CCTGGAGCTT TATTACCAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242723.1
CDS	105..326
Translation	MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVLKKWYTIFKDHVSLGDYEIHDGMNLELYYQ

Target ORF information:

RefSeq Version	XM_006242661.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ubiquitin-like 5 (Ubl5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242661.3

ORF Insert Sequence:

ATGATTGAGG TGGTTTGCAA CGACCGTCTA GGAAAGAAAG TCCGCGTTAA GTGCAACACC 
GATGACACCA TCGGCGACCT GAAGAAACTG ATAGCGGCTC AAACTGGCAC CCGCTGGAAT 
AAGATCGTTC TTAAAAAGTG GTACACGATT TTTAAAGACC ACGTGTCTCT GGGAGACTAT 
GAGATCCACG ACGGGATGAA CCTGGAGCTT TATTACCAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Nature504(7479)291-5(2013 Dec)
Hasson SA,Kane LA,Yamano K,Huang CH,Sliter DA,Buehler E,Wang C,Heman-Ackah SM,Hessa T,Guha R,Martin SE,Youle RJ

Down-regulation of the beacon gene expression in the regenerating rat adrenal cortex.
Peptides27(12)3216-9(2006 Dec)
Ziolkowska A,Rucinski M,Tyczewska M,Belloni AS,Nowak M,Nussdorfer GG,Malendowicz LK

Distribution of beacon immunoreactivity in the rat brain.
Peptides27(1)165-71(2006 Jan)
Wang F,Tian DR,Tian N,Chen H,Shi YS,Chang JK,Yang J,Yuan L,Han JS

Differential expression and function of beacon in the rat adrenal cortex and medulla.
International journal of molecular medicine16(1)35-40(2005 Jul)
Rucinski M,Andreis PG,Ziolkowska A,Nussdorfer GG,Malendowicz LK

Isolation of a ubiquitin-like (UBL5) gene from a screen identifying highly expressed and conserved iris genes.
Genomics71(2)252-5(2001 Jan)
Friedman JS,Koop BF,Raymond V,Walter MA