Napb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Napb
Entrez Gene ID	499903
Full Name	NSF attachment protein beta
Synonyms	SNAP-beta,Snapb
General protein information	Preferred Names NSF attachment protein beta Names beta-soluble NSF attachment protein N-ethylmaleimide sensitive fusion protein attachment protein beta N-ethylmaleimide-sensitive factor attachment protein beta
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q41

mRNA and Protein(s)

mRNA	Protein	Name
NM_001191966.1	NP_001178895.1	beta-soluble NSF attachment protein
XM_017591990.1	XP_017447479.1	beta-soluble NSF attachment protein isoform X1

Pathways from BioSystems

Homologies

	NAPB	XP_002798297.1
Xenopus tropicalis (tropical clawed frog)	napb	NP_001072566.1
Rattus norvegicus (Norway rat)	Napb	NP_001178895.1
Gallus gallus (chicken)	NAPB	NP_001186359.1
Homo sapiens (human)	NAPB	NP_071363.1
Canis lupus familiaris (dog)	NAPB	XP_534322.2
Mus musculus (house mouse)	Napb	NP_062606.1
Danio rerio (zebrafish)	zgc:158643	NP_001074171.1
Pan troglodytes (chimpanzee)	NAPB	XP_514551.3
Bos taurus (cattle)	NAPB	NP_001039698.1
Danio rerio (zebrafish)	napba	NP_001018491.1

Gene Ontology
Bibliography

Related articles in PubMed

SNARE protein recycling by ?SNAP and ?SNAP supports synaptic vesicle priming.
Burgalossi A, Jung S, Meyer G, Jockusch WJ, Jahn O, Taschenberger H, O'Connor VM, Nishiki T, Takahashi M, Brose N, Rhee JS
Neuron68(3)473-87(2010 Nov)

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Werner HB, Kuhlmann K, Shen S, Uecker M, Schardt A, Dimova K, Orfaniotou F, Dhaunchak A, Brinkmann BG, M?bius W, Guarente L, Casaccia-Bonnefil P, Jahn O, Nave KA
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)

Novel putative targets of N-ethylmaleimide sensitive fusion protein (NSF) and alpha/beta soluble NSF attachment proteins (SNAPs) include the Pak-binding nucleotide exchange factor betaPIX.
Martin HG, Henley JM, Meyer G
Journal of cellular biochemistry99(4)1203-15(2006 Nov)

The gene for soluble N-ethylmaleimide sensitive factor attachment protein alpha is mutated in hydrocephaly with hop gait (hyh) mice.
Hong HK, Chakravarti A, Takahashi JS
Proceedings of the National Academy of Sciences of the United States of America101(6)1748-53(2004 Feb)

NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex.
Hanley JG, Khatri L, Hanson PI, Ziff EB
Neuron34(1)53-67(2002 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A yeast two-hybrid screen using NSF as bait identified Rab11-FIP3 and the Pak-binding nucleotide exchange factor betaPIX as putative binding partners
Title: Novel putative targets of N-ethylmaleimide sensitive fusion protein (NSF) and alpha/beta soluble NSF attachment proteins (SNAPs) include the Pak-binding nucleotide exchange factor betaPIX.

The following Napb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Napb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08200	NM_001191966.1 Latest version!	Rattus norvegicus NSF attachment protein beta (Napb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa60515	XM_017591990.1 Latest version!	Rattus norvegicus NSF attachment protein beta (Napb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Napb ( NM_001191966.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001178895.1 Rattus norvegicus NSF attachment protein beta (Napb), mRNA.

Price & Availability↑

CloneID	ORa08200
Clone ID Related Accession (Same CDS sequence)	NM_001191966.1
Accession Version	NM_001191966.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-08-03
Organism	Rattus norvegicus(Norway rat)
Product	beta-soluble NSF attachment protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC110699.6. On Jul 17, 2010 this sequence version replaced XM_575249.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGACAACG CAGGGAAAGA ACGAGAAGCG GTCCAGCTTA TGGCGGAGGC CGAGAAGCGA 
GTGAAGGCTT CCCACTCCTT CCTCCGAGGG TTGTTCGGAG GAAACACAAG AATAGAAGAG 
GCATGTGAAA TGTATACCAG AGCTGCAAAT ATGTTCAAGA TGGCCAAGAA CTGGAGTGCT 
GCAGGAAATG CATTTTGTCA AGCCGCCAAG CTCCACATGC AGCTTCAGAG CAAGCATGAC 
TCTGCTACGA GCTTTGTGGA TGCTGGAAAT GCTTACAAGA AAGCAGACCC TCAAGAGGCT 
ATCAACTGCT TAAATGCAGC CATCGACATT TACACAGACA TGGGAAGATT CACAATCGCA 
GCCAAGCACC ATATCACCAT TGCTGAGATC TATGAGACTG AGCTCGTGGA CATTGAGAAG 
GCTATTGCAC ATTATGAACA ATCTGCTGAT TATTACAAAG GAGAAGAATC TAACAGCTCT 
GCTAACAAGT GTCTGCTGAA GGTGGCAGCC TATGCTGCAC AGCTGGAGCA GTACCAGAAA 
GCCATCGAGA TCTATGAGCA GGTGGGAGCA AACACTATGG ATAACCCCTT GCTGAAGTAC 
AGCGCAAAGG ATTACTTCTT CAAGGCAGCA CTCTGTCACT TCATAGTGGA TGAGCTGAAT 
GCAAAGCTTG CTCTTGAGAA ATACGAGGAA ATGTTTCCAG CATTTACTGA CTCCAGAGAA 
TGTAAATTAT TGAAAAAACT TCTAGAAGCT CATGAAGAAC AGAACAGTGA AGCTTACACT 
GAAGCAGTGA AGGAGTTTGA CTCAATATCA CGTTTGGATC AGTGGCTGAC TACCATGTTG 
CTTCGTATCA AGAAGTCCAT TCAAGGGGAT GGAGAAGGAG ATGGAGACCT CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178895.1
CDS	1..897
Translation	MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGEGDGDLK

Target ORF information:

RefSeq Version	NM_001191966.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus NSF attachment protein beta (Napb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191966.1

ORF Insert Sequence:

ATGGACAACG CAGGGAAAGA ACGAGAAGCG GTCCAGCTTA TGGCGGAGGC CGAGAAGCGA 
GTGAAGGCTT CCCACTCCTT CCTCCGAGGG TTGTTCGGAG GAAACACAAG AATAGAAGAG 
GCATGTGAAA TGTATACCAG AGCTGCAAAT ATGTTCAAGA TGGCCAAGAA CTGGAGTGCT 
GCAGGAAATG CATTTTGTCA AGCCGCCAAG CTCCACATGC AGCTTCAGAG CAAGCATGAC 
TCTGCTACGA GCTTTGTGGA TGCTGGAAAT GCTTACAAGA AAGCAGACCC TCAAGAGGCT 
ATCAACTGCT TAAATGCAGC CATCGACATT TACACAGACA TGGGAAGATT CACAATCGCA 
GCCAAGCACC ATATCACCAT TGCTGAGATC TATGAGACTG AGCTCGTGGA CATTGAGAAG 
GCTATTGCAC ATTATGAACA ATCTGCTGAT TATTACAAAG GAGAAGAATC TAACAGCTCT 
GCTAACAAGT GTCTGCTGAA GGTGGCAGCC TATGCTGCAC AGCTGGAGCA GTACCAGAAA 
GCCATCGAGA TCTATGAGCA GGTGGGAGCA AACACTATGG ATAACCCCTT GCTGAAGTAC 
AGCGCAAAGG ATTACTTCTT CAAGGCAGCA CTCTGTCACT TCATAGTGGA TGAGCTGAAT 
GCAAAGCTTG CTCTTGAGAA ATACGAGGAA ATGTTTCCAG CATTTACTGA CTCCAGAGAA 
TGTAAATTAT TGAAAAAACT TCTAGAAGCT CATGAAGAAC AGAACAGTGA AGCTTACACT 
GAAGCAGTGA AGGAGTTTGA CTCAATATCA CGTTTGGATC AGTGGCTGAC TACCATGTTG 
CTTCGTATCA AGAAGTCCAT TCAAGGGGAT GGAGAAGGAG ATGGAGACCT CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Napb ( XM_017591990.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447479.1 Rattus norvegicus NSF attachment protein beta (Napb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa60515
Clone ID Related Accession (Same CDS sequence)	XM_017591990.1
Accession Version	XM_017591990.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 615bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	beta-soluble NSF attachment protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTCTGC TACGAGCTTT GTGGATGCTG GAAATGCTTA CAAGAAAGCA GACCCTCAAG 
GGAAGATTCA CAATCGCAGC CAAGCACCAT ATCACCATTG CTGAGATCTA TGAGACTGAG 
CTCGTGGACA TTGAGAAGGC TATTGCACAT TATGAACAAT CTGCTGATTA TTACAAAGGA 
GAAGAATCTA ACAGCTCTGC TAACAAGTGT CTGCTGAAGG TGGCAGCCTA TGCTGCACAG 
CTGGAGCAGT ACCAGAAAGC CATCGAGATC TATGAGCAGG TGGGAGCAAA CACTATGGAT 
AACCCCTTGC TGAAGTACAG CGCAAAGGAT TACTTCTTCA AGGCAGCACT CTGTCACTTC 
ATAGTGGATG AGCTGAATGC AAAGCTTGCT CTTGAGAAAT ACGAGGAAAT GTTTCCAGCA 
TTTACTGACT CCAGAGAATG TAAATTATTG AAAAAACTTC TAGAAGCTCA TGAAGAACAG 
AACAGTGAAG CTTACACTGA AGCAGTGAAG GAGTTTGACT CAATATCACG TTTGGATCAG 
TGGCTGACTA CCATGTTGCT TCGTATCAAG AAGTCCATTC AAGGGGATGG AGAAGGAGAT 
GGAGACCTCA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447479.1
CDS	1..615
Translation	MTLLRALWMLEMLTRKQTLKGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGEGDGDLK

Target ORF information:

RefSeq Version	XM_017591990.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus NSF attachment protein beta (Napb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591990.1

ORF Insert Sequence:

ATGACTCTGC TACGAGCTTT GTGGATGCTG GAAATGCTTA CAAGAAAGCA GACCCTCAAG 
GGAAGATTCA CAATCGCAGC CAAGCACCAT ATCACCATTG CTGAGATCTA TGAGACTGAG 
CTCGTGGACA TTGAGAAGGC TATTGCACAT TATGAACAAT CTGCTGATTA TTACAAAGGA 
GAAGAATCTA ACAGCTCTGC TAACAAGTGT CTGCTGAAGG TGGCAGCCTA TGCTGCACAG 
CTGGAGCAGT ACCAGAAAGC CATCGAGATC TATGAGCAGG TGGGAGCAAA CACTATGGAT 
AACCCCTTGC TGAAGTACAG CGCAAAGGAT TACTTCTTCA AGGCAGCACT CTGTCACTTC 
ATAGTGGATG AGCTGAATGC AAAGCTTGCT CTTGAGAAAT ACGAGGAAAT GTTTCCAGCA 
TTTACTGACT CCAGAGAATG TAAATTATTG AAAAAACTTC TAGAAGCTCA TGAAGAACAG 
AACAGTGAAG CTTACACTGA AGCAGTGAAG GAGTTTGACT CAATATCACG TTTGGATCAG 
TGGCTGACTA CCATGTTGCT TCGTATCAAG AAGTCCATTC AAGGGGATGG AGAAGGAGAT 
GGAGACCTCA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SNARE protein recycling by ?SNAP and ?SNAP supports synaptic vesicle priming.
Neuron68(3)473-87(2010 Nov)
Burgalossi A,Jung S,Meyer G,Jockusch WJ,Jahn O,Taschenberger H,O'Connor VM,Nishiki T,Takahashi M,Brose N,Rhee JS

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)
Werner HB,Kuhlmann K,Shen S,Uecker M,Schardt A,Dimova K,Orfaniotou F,Dhaunchak A,Brinkmann BG,M?bius W,Guarente L,Casaccia-Bonnefil P,Jahn O,Nave KA

Novel putative targets of N-ethylmaleimide sensitive fusion protein (NSF) and alpha/beta soluble NSF attachment proteins (SNAPs) include the Pak-binding nucleotide exchange factor betaPIX.
Journal of cellular biochemistry99(4)1203-15(2006 Nov)
Martin HG,Henley JM,Meyer G

The gene for soluble N-ethylmaleimide sensitive factor attachment protein alpha is mutated in hydrocephaly with hop gait (hyh) mice.
Proceedings of the National Academy of Sciences of the United States of America101(6)1748-53(2004 Feb)
Hong HK,Chakravarti A,Takahashi JS

NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex.
Neuron34(1)53-67(2002 Mar)
Hanley JG,Khatri L,Hanson PI,Ziff EB