Tlx1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tlx1
Entrez Gene ID	499361
Full Name	T-cell leukemia, homeobox 1
Synonyms	RGD1563655
General protein information	Preferred Names T-cell leukemia, homeobox 1 Names T-cell leukemia homeobox protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q54

mRNA and Protein(s)

mRNA	Protein	Name
XM_006231554.3	XP_006231616.1	T-cell leukemia homeobox protein 1 isoform X1
NM_001109166.1	NP_001102636.1	T-cell leukemia homeobox protein 1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	TLX1	NP_990346.1
Danio rerio (zebrafish)	tlx1	NP_739571.1
Pan troglodytes (chimpanzee)	TLX1	XP_001169592.2
Canis lupus familiaris (dog)	TLX1	XP_850598.1
Bos taurus (cattle)	TLX1	NP_001178986.1
Mus musculus (house mouse)	Tlx1	NP_068701.1
Rattus norvegicus (Norway rat)	Tlx1	NP_001102636.1
Homo sapiens (human)	TLX1	NP_005512.1
	LOC711584	XP_001109904.1
Xenopus tropicalis (tropical clawed frog)	tlx1	XP_002936814.1

Gene Ontology
Bibliography

Related articles in PubMed

A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny.
Brendolan A, Ferretti E, Salsi V, Moses K, Quaggin S, Blasi F, Cleary ML, Selleri L
Development (Cambridge, England)132(13)3113-26(2005 Jul)

Proper development of relay somatic sensory neurons and D2/D4 interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1.
Qian Y, Shirasawa S, Chen CL, Cheng L, Ma Q
Genes & development16(10)1220-33(2002 May)

Hox11 acts cell autonomously in spleen development and its absence results in altered cell fate of mesenchymal spleen precursors.
Kanzler B, Dear TN
Developmental biology234(1)231-43(2001 Jun)

A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t(10;14).
Dub? ID, Kamel-Reid S, Yuan CC, Lu M, Wu X, Corpus G, Raimondi SC, Crist WM, Carroll AJ, Minowada J
Blood78(11)2996-3003(1991 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tlx1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tlx1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09199	NM_001109166.1 Latest version!	Rattus norvegicus T-cell leukemia, homeobox 1 (Tlx1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
ORa24207	XM_006231554.3 Latest version!	Rattus norvegicus T-cell leukemia, homeobox 1 (Tlx1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tlx1 ( NM_001109166.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102636.1 Rattus norvegicus T-cell leukemia, homeobox 1 (Tlx1), mRNA.

Price & Availability↑

CloneID	ORa09199
Clone ID Related Accession (Same CDS sequence)	NM_001109166.1
Accession Version	NM_001109166.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	T-cell leukemia homeobox protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473986.1. On or before Oct 4, 2007 this sequence version replaced XM_001057997.1, XM_574674.2. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689603, SAMN02642638 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCACC TGGGTCCGCA CCATCTCCAC CCGGGCCACG CGGAGCCCAT CAGCTTCGGC 
ATCGACCAGA TCCTCAACAG CCCGGACCAG GGCGGCTGCA TGGGGCCCGC CTCGCGCCTC 
CAGGACGGAG AATACGGCCT TGGCTGTTTG GTCGGAGGCG CCTACACTTA TGGCGGAGGG 
GGTTCCGCCG CTGGAGCGGG GGCCGGGGGC ACAGGCGCTT ACGGCACCGG TGGCCCGGGT 
GGTCCCGGAG GCCCGGCGGG CGGTGGCGGA GGTGCCTGCA GCATGGGCCC ACTGGCCGGC 
TCCTACAACG TGAACATGGC CTTGGCGGGC GGCCCGGGTC CGGGAGGCGG CGGCGGTGGC 
GCGGGTGCCG GTGGCGCCGG TGCGCTGAGC GCTGCAGGGG TGATCCGGGT GCCCGCGCAC 
AGGCCGCTAG CTGGAGCTGT GGCCCATCCC CAGCCCCTGG CCACCGGCTT GCCTACTGTG 
CCCTCTGTGC CTGCGGTGCC GGGTGTCAAC AACCTCACCG GCCTCACCTT CCCCTGGATG 
GAGAGTAACC GCAGATACAC AAAGGACAGG TTCACAGGTC ACCCCTATCA GAACCGGACG 
CCCCCTAAGA AGAAGAAGCC GCGTACATCC TTCACACGCC TGCAGATCTG TGAGCTGGAA 
AAGCGCTTCC ACCGCCAGAA GTACTTGGCT TCGGCGGAGC GCGCTGCTCT GGCCAAAGCG 
CTCAAAATGA CCGATGCGCA AGTCAAAACC TGGTTCCAGA ACAGGAGGAC GAAATGGAGG 
CGACAGACAG CAGAGGAGCG TGAGGCCGAG AGGCAGCAGG CGAACCGCAT CCTCTTGCAG 
CTGCAGCAGG AGGCCTTCCA GAAGAGCCTG GCCCAGCCGC TGCCTGCAGA CCCACTGTGC 
GTGCACAACT CGTCGCTCTT TGCCCTGCAG AACCTGCAGC CGTGGTCTGA CGACTCCACC 
AAAATCACTA GCGTCACGTC CGTGGCTTCG GCCTGTGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102636.1
CDS	202..1203
Translation	MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAGAGAGGTGAYGTGGPGGPGGPAGGGGGACSMGPLAGSYNVNMALAGGPGPGGGGGGAGAGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAVPGVNNLTGLTFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE

Target ORF information:

RefSeq Version	NM_001109166.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus T-cell leukemia, homeobox 1 (Tlx1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001109166.1

ORF Insert Sequence:

ATGGAGCACC TGGGTCCGCA CCATCTCCAC CCGGGCCACG CGGAGCCCAT CAGCTTCGGC 
ATCGACCAGA TCCTCAACAG CCCGGACCAG GGCGGCTGCA TGGGGCCCGC CTCGCGCCTC 
CAGGACGGAG AATACGGCCT TGGCTGTTTG GTCGGAGGCG CCTACACTTA TGGCGGAGGG 
GGTTCCGCCG CTGGAGCGGG GGCCGGGGGC ACAGGCGCTT ACGGCACCGG TGGCCCGGGT 
GGTCCCGGAG GCCCGGCGGG CGGTGGCGGA GGTGCCTGCA GCATGGGCCC ACTGGCCGGC 
TCCTACAACG TGAACATGGC CTTGGCGGGC GGCCCGGGTC CGGGAGGCGG CGGCGGTGGC 
GCGGGTGCCG GTGGCGCCGG TGCGCTGAGC GCTGCAGGGG TGATCCGGGT GCCCGCGCAC 
AGGCCGCTAG CTGGAGCTGT GGCCCATCCC CAGCCCCTGG CCACCGGCTT GCCTACTGTG 
CCCTCTGTGC CTGCGGTGCC GGGTGTCAAC AACCTCACCG GCCTCACCTT CCCCTGGATG 
GAGAGTAACC GCAGATACAC AAAGGACAGG TTCACAGGTC ACCCCTATCA GAACCGGACG 
CCCCCTAAGA AGAAGAAGCC GCGTACATCC TTCACACGCC TGCAGATCTG TGAGCTGGAA 
AAGCGCTTCC ACCGCCAGAA GTACTTGGCT TCGGCGGAGC GCGCTGCTCT GGCCAAAGCG 
CTCAAAATGA CCGATGCGCA AGTCAAAACC TGGTTCCAGA ACAGGAGGAC GAAATGGAGG 
CGACAGACAG CAGAGGAGCG TGAGGCCGAG AGGCAGCAGG CGAACCGCAT CCTCTTGCAG 
CTGCAGCAGG AGGCCTTCCA GAAGAGCCTG GCCCAGCCGC TGCCTGCAGA CCCACTGTGC 
GTGCACAACT CGTCGCTCTT TGCCCTGCAG AACCTGCAGC CGTGGTCTGA CGACTCCACC 
AAAATCACTA GCGTCACGTC CGTGGCTTCG GCCTGTGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tlx1 ( XM_006231554.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231616.1 Rattus norvegicus T-cell leukemia, homeobox 1 (Tlx1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa24207
Clone ID Related Accession (Same CDS sequence)	XM_006231554.3
Accession Version	XM_006231554.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1038bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	T-cell leukemia homeobox protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231554.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCACC TGGGTCCGCA CCATCTCCAC CCGGGCCACG CGGAGCCCAT CAGCTTCGGC 
ATCGACCAGA TCCTCAACAG CCCGGACCAG GGCGGCTGCA TGGGGCCCGC CTCGCGCCTC 
CAGGACGGAG AATACGGCCT TGGCTGTTTG GTCGGAGGCG CCTACACTTA TGGCGGAGGG 
GGTTCCGCCG CTGGAGCGGG GGCCGGGGGC ACAGGCGCTT ACGGCACCGG TGGCCCGGGT 
GGTCCCGGAG GCCCGGCGGG CGGTGGCGGA GGTGCCTGCA GCATGGGCCC ACTGGCCGGC 
TCCTACAACG TGAACATGGC CTTGGCGGGC GGCCCGGGTC CGGGAGGCGG CGGCGGTGGC 
GCGGGTGCCG GTGGCGCCGG TGCGCTGAGC GCTGCAGGGG TGATCCGGGT GCCCGCGCAC 
AGGCCGCTAG CTGGAGCTGT GGCCCATCCC CAGCCCCTGG CCACCGGCTT GCCTACTGTG 
CCCTCTGTGC CTGCGGTGCC GGGTGTCAAC AACCTCACCG GCCTCACCTT CCCCTGGATG 
GAGAGTAACC GCAGATACAC AAAGGACAGG TTCACAGTGG CCCTCTCACC CTTCACTGTA 
ACACGCCGTA TAGGTCACCC CTATCAGAAC CGGACGCCCC CTAAGAAGAA GAAGCCGCGT 
ACATCCTTCA CACGCCTGCA GATCTGTGAG CTGGAAAAGC GCTTCCACCG CCAGAAGTAC 
TTGGCTTCGG CGGAGCGCGC TGCTCTGGCC AAAGCGCTCA AAATGACCGA TGCGCAAGTC 
AAAACCTGGT TCCAGAACAG GAGGACGAAA TGGAGGCGAC AGACAGCAGA GGAGCGTGAG 
GCCGAGAGGC AGCAGGCGAA CCGCATCCTC TTGCAGCTGC AGCAGGAGGC CTTCCAGAAG 
AGCCTGGCCC AGCCGCTGCC TGCAGACCCA CTGTGCGTGC ACAACTCGTC GCTCTTTGCC 
CTGCAGAACC TGCAGCCGTG GTCTGACGAC TCCACCAAAA TCACTAGCGT CACGTCCGTG 
GCTTCGGCCT GTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231616.1
CDS	331..1368
Translation	MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAGAGAGGTGAYGTGGPGGPGGPAGGGGGACSMGPLAGSYNVNMALAGGPGPGGGGGGAGAGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAVPGVNNLTGLTFPWMESNRRYTKDRFTVALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE

Target ORF information:

RefSeq Version	XM_006231554.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus T-cell leukemia, homeobox 1 (Tlx1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231554.3

ORF Insert Sequence:

ATGGAGCACC TGGGTCCGCA CCATCTCCAC CCGGGCCACG CGGAGCCCAT CAGCTTCGGC 
ATCGACCAGA TCCTCAACAG CCCGGACCAG GGCGGCTGCA TGGGGCCCGC CTCGCGCCTC 
CAGGACGGAG AATACGGCCT TGGCTGTTTG GTCGGAGGCG CCTACACTTA TGGCGGAGGG 
GGTTCCGCCG CTGGAGCGGG GGCCGGGGGC ACAGGCGCTT ACGGCACCGG TGGCCCGGGT 
GGTCCCGGAG GCCCGGCGGG CGGTGGCGGA GGTGCCTGCA GCATGGGCCC ACTGGCCGGC 
TCCTACAACG TGAACATGGC CTTGGCGGGC GGCCCGGGTC CGGGAGGCGG CGGCGGTGGC 
GCGGGTGCCG GTGGCGCCGG TGCGCTGAGC GCTGCAGGGG TGATCCGGGT GCCCGCGCAC 
AGGCCGCTAG CTGGAGCTGT GGCCCATCCC CAGCCCCTGG CCACCGGCTT GCCTACTGTG 
CCCTCTGTGC CTGCGGTGCC GGGTGTCAAC AACCTCACCG GCCTCACCTT CCCCTGGATG 
GAGAGTAACC GCAGATACAC AAAGGACAGG TTCACAGTGG CCCTCTCACC CTTCACTGTA 
ACACGCCGTA TAGGTCACCC CTATCAGAAC CGGACGCCCC CTAAGAAGAA GAAGCCGCGT 
ACATCCTTCA CACGCCTGCA GATCTGTGAG CTGGAAAAGC GCTTCCACCG CCAGAAGTAC 
TTGGCTTCGG CGGAGCGCGC TGCTCTGGCC AAAGCGCTCA AAATGACCGA TGCGCAAGTC 
AAAACCTGGT TCCAGAACAG GAGGACGAAA TGGAGGCGAC AGACAGCAGA GGAGCGTGAG 
GCCGAGAGGC AGCAGGCGAA CCGCATCCTC TTGCAGCTGC AGCAGGAGGC CTTCCAGAAG 
AGCCTGGCCC AGCCGCTGCC TGCAGACCCA CTGTGCGTGC ACAACTCGTC GCTCTTTGCC 
CTGCAGAACC TGCAGCCGTG GTCTGACGAC TCCACCAAAA TCACTAGCGT CACGTCCGTG 
GCTTCGGCCT GTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny.
Development (Cambridge, England)132(13)3113-26(2005 Jul)
Brendolan A,Ferretti E,Salsi V,Moses K,Quaggin S,Blasi F,Cleary ML,Selleri L

Proper development of relay somatic sensory neurons and D2/D4 interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1.
Genes & development16(10)1220-33(2002 May)
Qian Y,Shirasawa S,Chen CL,Cheng L,Ma Q

Hox11 acts cell autonomously in spleen development and its absence results in altered cell fate of mesenchymal spleen precursors.
Developmental biology234(1)231-43(2001 Jun)
Kanzler B,Dear TN

A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t(10;14).
Blood78(11)2996-3003(1991 Dec)
Dub? ID,Kamel-Reid S,Yuan CC,Lu M,Wu X,Corpus G,Raimondi SC,Crist WM,Carroll AJ,Minowada J