Blk cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Blk
Entrez Gene ID	364403
Full Name	BLK proto-oncogene, Src family tyrosine kinase
General protein information	Preferred Names BLK proto-oncogene, Src family tyrosine kinase Names tyrosine-protein kinase Blk B lymphoid tyrosine kinase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001025751.1	NP_001020922.1	tyrosine-protein kinase Blk
XM_006252188.3	XP_006252250.1	tyrosine-protein kinase Blk isoform X1
XM_008770770.1	XP_008768992.1	tyrosine-protein kinase Blk isoform X2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	BLK	NP_001069436.1
Rattus norvegicus (Norway rat)	Blk	NP_001020922.1
Homo sapiens (human)	BLK	NP_001706.2
Gallus gallus (chicken)	BLK	XP_420040.4
Danio rerio (zebrafish)	blk	NP_001025391.1
Canis lupus familiaris (dog)	BLK	XP_543206.2
Mus musculus (house mouse)	Blk	NP_031575.2
Xenopus tropicalis (tropical clawed frog)	blk	XP_002933650.2
Pan troglodytes (chimpanzee)	BLK	XP_003317961.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction.
Borowiec M, Liew CW, Thompson R, Boonyasrisawat W, Hu J, Mlynarski WM, El Khattabi I, Kim SH, Marselli L, Rich SS, Krolewski AS, Bonner-Weir S, Sharma A, Sale M, Mychaleckyj JC, Kulkarni RN, Doria A
Proceedings of the National Academy of Sciences of the United States of America106(34)14460-5(2009 Aug)

Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population.
Ito I, Kawasaki A, Ito S, Hayashi T, Goto D, Matsumoto I, Tsutsumi A, Hom G, Graham RR, Takasaki Y, Hashimoto H, Ohashi J, Behrens TW, Sumida T, Tsuchiya N
Arthritis and rheumatism60(2)553-8(2009 Feb)

The effect of cardiac ischemic preconditioning on rat left ventricular gene expression profile.
Canatan H
Cell biochemistry and function26(2)179-84(2008 Mar-Apr)

[Restoration of the function of bilateral hand grip at the expense of the fingers of the same hand].
Azolov VV
Ortopediia travmatologiia i protezirovanie(4)60-5(1977 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Blk gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Blk cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07652	NM_001025751.1 Latest version!	Rattus norvegicus BLK proto-oncogene, Src family tyrosine kinase (Blk), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa07652	XM_008770770.1 Latest version!	Rattus norvegicus BLK proto-oncogene, Src family tyrosine kinase (Blk), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa36801	XM_006252188.3 Latest version!	Rattus norvegicus BLK proto-oncogene, Src family tyrosine kinase (Blk), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Blk ( NM_001025751.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001020922.1 Rattus norvegicus BLK proto-oncogene, Src family tyrosine kinase (Blk), mRNA.

Price & Availability↑

CloneID	ORa07652
Clone ID Related Accession (Same CDS sequence)	NM_001025751.1 , XM_008770770.1
Accession Version	NM_001025751.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	tyrosine-protein kinase Blk
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC098683.1. On Jul 22, 2005 this sequence version replaced XM_344419.2. ##Evidence-Data-START## Transcript exon combination :: BC098683.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052297, SAMEA2689594 [ECO:0000350] ##Evidence-Data-END##

ATGGGGCTAC TGAGCAGCAA GAGGCAGATC AGCGAGAAGA GCAAGAGCTG GAGCCCTGTG 
AAGGCCCGCG CCCAGGGCAA GGTACCCCCG CCCCTGCCAC CCCTGGTTGT CTTCAACCAC 
CTCCCTCCTC CATCTCCTAA CCAGCACCCA GATGAAGAGG AGCGTTTTGT GGTGGCCCTG 
TTTGACTATG CCGCTGTGAA TGACAGGGAC CTGCAAGTGC TAAAGGGAGA GAAGCTCCAA 
GTCTTGAAGA GCACTGGAGA CTGGTGGTTG GCCAGGTCAC TCGTCACAGG AAGAGAAGGC 
TATGTGCCCA GCAACTTTGT GGCCCCAGTA GAGACCCTGG AAGTAGAAAA ATGGTTCTTC 
AGGACCATTA GCCGGAAGGA TGCTGAGAGG CAGTTGCTGG CTCCAATGAA CAAAGCCGGC 
TCCTTTCTCA TCAGAGAGAG TGAGAGCAAT AAAGGTGCCT TTTCCCTATC TGTGAAAGAC 
GTCACCAGCC AGGGGGAGAT GGTCAAGCAC TATAAGATCC GCTCACTGGA CAATGGAGGC 
TATTACATCT CGCCCCGGAT CACCTTCCCC ACCCTCCAGG CCCTGGTGCA GCACTATTCT 
GAGAAAGGGG ACGGTTTGTG TCAGAAGTTG ACCCTGCCCT GTGTGAACCC AGCCCCGAAG 
AATCCCTGGG CCCAAGACGA ATGGGAAATC CCCAGGCAGT CCCTCAAGTT GGTCCGGAAA 
CTTGGGTCTG GGCAGTTTGG TGAAGTCTGG ATGGGTTATT ACAAAAATAA CATGAAGGTG 
GCAATCAAGA CCCTGAAGGA GGGAACCATG TCTCCGGAAG CTTTCCTGGG TGAGGCCAAC 
GTGATGAAAA CCCTGCAGCA TGAGAGGCTG GTCCGTCTCT ACGCCGTGGT CACCAGAGAG 
CCCATCTACA TTGTCACGGA ATACATGGCC AGAGGATGCT TGCTGGATTT TCTGAAGACC 
GATGAAGGTA GCAGATTGTC CCTTCCAAGG CTGATTGACA TGTCAGCCCA GGTTGCAGAA 
GGGATGGCTT ACATAGAGCG CATGAATTCC ATCCACCGTG ACCTGCGGGC AGCCAACATC 
CTGGTGTCTG AGACCTTGTG CTGCAAAATC GCTGACTTCG GCTTGGCCAG GATCATCGAC 
AGTGAATATA CTGCCCAAGA GGGGGCCAAG TTCCCCATCA AGTGGACTGC CCCAGAAGCC 
ATCCACTTCG GGGTGTTTAC CATCAAGGCT GATGTGTGGT CCTTTGGAGT CTTGCTGATG 
GAGATTGTCA CATATGGGCG TGTTCCCTAC CCAGGAATGA GCAACCCTGA GGTCATCCGT 
AGCCTGGAGC ATGGCTACCG AATGCCATGC CCAGAGACAT GTCCGCCTGA GTTGTACCAT 
GACGTCATCA CTGAGTGCTG GCGAGGCCGA CCTGAGGAGC GGCCTACCTT TGAGTTCCTG 
CAGTCAGTGC TGGAGGACTT CTACACAGCC ACGGAGGGCC AATATGAGCT GCAGCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020922.1
CDS	353..1852
Translation	MGLLSSKRQISEKSKSWSPVKARAQGKVPPPLPPLVVFNHLPPPSPNQHPDEEERFVVALFDYAAVNDRDLQVLKGEKLQVLKSTGDWWLARSLVTGREGYVPSNFVAPVETLEVEKWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDVTSQGEMVKHYKIRSLDNGGYYISPRITFPTLQALVQHYSEKGDGLCQKLTLPCVNPAPKNPWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKTLQHERLVRLYAVVTREPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYHDVITECWRGRPEERPTFEFLQSVLEDFYTATEGQYELQP

Target ORF information:

RefSeq Version	NM_001025751.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BLK proto-oncogene, Src family tyrosine kinase (Blk), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025751.1

ORF Insert Sequence:

ATGGGGCTAC TGAGCAGCAA GAGGCAGATC AGCGAGAAGA GCAAGAGCTG GAGCCCTGTG 
AAGGCCCGCG CCCAGGGCAA GGTACCCCCG CCCCTGCCAC CCCTGGTTGT CTTCAACCAC 
CTCCCTCCTC CATCTCCTAA CCAGCACCCA GATGAAGAGG AGCGTTTTGT GGTGGCCCTG 
TTTGACTATG CCGCTGTGAA TGACAGGGAC CTGCAAGTGC TAAAGGGAGA GAAGCTCCAA 
GTCTTGAAGA GCACTGGAGA CTGGTGGTTG GCCAGGTCAC TCGTCACAGG AAGAGAAGGC 
TATGTGCCCA GCAACTTTGT GGCCCCAGTA GAGACCCTGG AAGTAGAAAA ATGGTTCTTC 
AGGACCATTA GCCGGAAGGA TGCTGAGAGG CAGTTGCTGG CTCCAATGAA CAAAGCCGGC 
TCCTTTCTCA TCAGAGAGAG TGAGAGCAAT AAAGGTGCCT TTTCCCTATC TGTGAAAGAC 
GTCACCAGCC AGGGGGAGAT GGTCAAGCAC TATAAGATCC GCTCACTGGA CAATGGAGGC 
TATTACATCT CGCCCCGGAT CACCTTCCCC ACCCTCCAGG CCCTGGTGCA GCACTATTCT 
GAGAAAGGGG ACGGTTTGTG TCAGAAGTTG ACCCTGCCCT GTGTGAACCC AGCCCCGAAG 
AATCCCTGGG CCCAAGACGA ATGGGAAATC CCCAGGCAGT CCCTCAAGTT GGTCCGGAAA 
CTTGGGTCTG GGCAGTTTGG TGAAGTCTGG ATGGGTTATT ACAAAAATAA CATGAAGGTG 
GCAATCAAGA CCCTGAAGGA GGGAACCATG TCTCCGGAAG CTTTCCTGGG TGAGGCCAAC 
GTGATGAAAA CCCTGCAGCA TGAGAGGCTG GTCCGTCTCT ACGCCGTGGT CACCAGAGAG 
CCCATCTACA TTGTCACGGA ATACATGGCC AGAGGATGCT TGCTGGATTT TCTGAAGACC 
GATGAAGGTA GCAGATTGTC CCTTCCAAGG CTGATTGACA TGTCAGCCCA GGTTGCAGAA 
GGGATGGCTT ACATAGAGCG CATGAATTCC ATCCACCGTG ACCTGCGGGC AGCCAACATC 
CTGGTGTCTG AGACCTTGTG CTGCAAAATC GCTGACTTCG GCTTGGCCAG GATCATCGAC 
AGTGAATATA CTGCCCAAGA GGGGGCCAAG TTCCCCATCA AGTGGACTGC CCCAGAAGCC 
ATCCACTTCG GGGTGTTTAC CATCAAGGCT GATGTGTGGT CCTTTGGAGT CTTGCTGATG 
GAGATTGTCA CATATGGGCG TGTTCCCTAC CCAGGAATGA GCAACCCTGA GGTCATCCGT 
AGCCTGGAGC ATGGCTACCG AATGCCATGC CCAGAGACAT GTCCGCCTGA GTTGTACCAT 
GACGTCATCA CTGAGTGCTG GCGAGGCCGA CCTGAGGAGC GGCCTACCTT TGAGTTCCTG 
CAGTCAGTGC TGGAGGACTT CTACACAGCC ACGGAGGGCC AATATGAGCT GCAGCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Blk ( XM_008770770.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008768992.1 Rattus norvegicus BLK proto-oncogene, Src family tyrosine kinase (Blk), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa07652
Clone ID Related Accession (Same CDS sequence)	NM_001025751.1 , XM_008770770.1
Accession Version	XM_008770770.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tyrosine-protein kinase Blk isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTAC TGAGCAGCAA GAGGCAGATC AGCGAGAAGA GCAAGAGCTG GAGCCCTGTG 
AAGGCCCGCG CCCAGGGCAA GGTACCCCCG CCCCTGCCAC CCCTGGTTGT CTTCAACCAC 
CTCCCTCCTC CATCTCCTAA CCAGCACCCA GATGAAGAGG AGCGTTTTGT GGTGGCCCTG 
TTTGACTATG CCGCTGTGAA TGACAGGGAC CTGCAAGTGC TAAAGGGAGA GAAGCTCCAA 
GTCTTGAAGA GCACTGGAGA CTGGTGGTTG GCCAGGTCAC TCGTCACAGG AAGAGAAGGC 
TATGTGCCCA GCAACTTTGT GGCCCCAGTA GAGACCCTGG AAGTAGAAAA ATGGTTCTTC 
AGGACCATTA GCCGGAAGGA TGCTGAGAGG CAGTTGCTGG CTCCAATGAA CAAAGCCGGC 
TCCTTTCTCA TCAGAGAGAG TGAGAGCAAT AAAGGTGCCT TTTCCCTATC TGTGAAAGAC 
GTCACCAGCC AGGGGGAGAT GGTCAAGCAC TATAAGATCC GCTCACTGGA CAATGGAGGC 
TATTACATCT CGCCCCGGAT CACCTTCCCC ACCCTCCAGG CCCTGGTGCA GCACTATTCT 
GAGAAAGGGG ACGGTTTGTG TCAGAAGTTG ACCCTGCCCT GTGTGAACCC AGCCCCGAAG 
AATCCCTGGG CCCAAGACGA ATGGGAAATC CCCAGGCAGT CCCTCAAGTT GGTCCGGAAA 
CTTGGGTCTG GGCAGTTTGG TGAAGTCTGG ATGGGTTATT ACAAAAATAA CATGAAGGTG 
GCAATCAAGA CCCTGAAGGA GGGAACCATG TCTCCGGAAG CTTTCCTGGG TGAGGCCAAC 
GTGATGAAAA CCCTGCAGCA TGAGAGGCTG GTCCGTCTCT ACGCCGTGGT CACCAGAGAG 
CCCATCTACA TTGTCACGGA ATACATGGCC AGAGGATGCT TGCTGGATTT TCTGAAGACC 
GATGAAGGTA GCAGATTGTC CCTTCCAAGG CTGATTGACA TGTCAGCCCA GGTTGCAGAA 
GGGATGGCTT ACATAGAGCG CATGAATTCC ATCCACCGTG ACCTGCGGGC AGCCAACATC 
CTGGTGTCTG AGACCTTGTG CTGCAAAATC GCTGACTTCG GCTTGGCCAG GATCATCGAC 
AGTGAATATA CTGCCCAAGA GGGGGCCAAG TTCCCCATCA AGTGGACTGC CCCAGAAGCC 
ATCCACTTCG GGGTGTTTAC CATCAAGGCT GATGTGTGGT CCTTTGGAGT CTTGCTGATG 
GAGATTGTCA CATATGGGCG TGTTCCCTAC CCAGGAATGA GCAACCCTGA GGTCATCCGT 
AGCCTGGAGC ATGGCTACCG AATGCCATGC CCAGAGACAT GTCCGCCTGA GTTGTACCAT 
GACGTCATCA CTGAGTGCTG GCGAGGCCGA CCTGAGGAGC GGCCTACCTT TGAGTTCCTG 
CAGTCAGTGC TGGAGGACTT CTACACAGCC ACGGAGGGCC AATATGAGCT GCAGCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008768992.1
CDS	13..1512
Translation	MGLLSSKRQISEKSKSWSPVKARAQGKVPPPLPPLVVFNHLPPPSPNQHPDEEERFVVALFDYAAVNDRDLQVLKGEKLQVLKSTGDWWLARSLVTGREGYVPSNFVAPVETLEVEKWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDVTSQGEMVKHYKIRSLDNGGYYISPRITFPTLQALVQHYSEKGDGLCQKLTLPCVNPAPKNPWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKTLQHERLVRLYAVVTREPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYHDVITECWRGRPEERPTFEFLQSVLEDFYTATEGQYELQP

Target ORF information:

RefSeq Version	XM_008770770.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BLK proto-oncogene, Src family tyrosine kinase (Blk), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008770770.1

ORF Insert Sequence:

ATGGGGCTAC TGAGCAGCAA GAGGCAGATC AGCGAGAAGA GCAAGAGCTG GAGCCCTGTG 
AAGGCCCGCG CCCAGGGCAA GGTACCCCCG CCCCTGCCAC CCCTGGTTGT CTTCAACCAC 
CTCCCTCCTC CATCTCCTAA CCAGCACCCA GATGAAGAGG AGCGTTTTGT GGTGGCCCTG 
TTTGACTATG CCGCTGTGAA TGACAGGGAC CTGCAAGTGC TAAAGGGAGA GAAGCTCCAA 
GTCTTGAAGA GCACTGGAGA CTGGTGGTTG GCCAGGTCAC TCGTCACAGG AAGAGAAGGC 
TATGTGCCCA GCAACTTTGT GGCCCCAGTA GAGACCCTGG AAGTAGAAAA ATGGTTCTTC 
AGGACCATTA GCCGGAAGGA TGCTGAGAGG CAGTTGCTGG CTCCAATGAA CAAAGCCGGC 
TCCTTTCTCA TCAGAGAGAG TGAGAGCAAT AAAGGTGCCT TTTCCCTATC TGTGAAAGAC 
GTCACCAGCC AGGGGGAGAT GGTCAAGCAC TATAAGATCC GCTCACTGGA CAATGGAGGC 
TATTACATCT CGCCCCGGAT CACCTTCCCC ACCCTCCAGG CCCTGGTGCA GCACTATTCT 
GAGAAAGGGG ACGGTTTGTG TCAGAAGTTG ACCCTGCCCT GTGTGAACCC AGCCCCGAAG 
AATCCCTGGG CCCAAGACGA ATGGGAAATC CCCAGGCAGT CCCTCAAGTT GGTCCGGAAA 
CTTGGGTCTG GGCAGTTTGG TGAAGTCTGG ATGGGTTATT ACAAAAATAA CATGAAGGTG 
GCAATCAAGA CCCTGAAGGA GGGAACCATG TCTCCGGAAG CTTTCCTGGG TGAGGCCAAC 
GTGATGAAAA CCCTGCAGCA TGAGAGGCTG GTCCGTCTCT ACGCCGTGGT CACCAGAGAG 
CCCATCTACA TTGTCACGGA ATACATGGCC AGAGGATGCT TGCTGGATTT TCTGAAGACC 
GATGAAGGTA GCAGATTGTC CCTTCCAAGG CTGATTGACA TGTCAGCCCA GGTTGCAGAA 
GGGATGGCTT ACATAGAGCG CATGAATTCC ATCCACCGTG ACCTGCGGGC AGCCAACATC 
CTGGTGTCTG AGACCTTGTG CTGCAAAATC GCTGACTTCG GCTTGGCCAG GATCATCGAC 
AGTGAATATA CTGCCCAAGA GGGGGCCAAG TTCCCCATCA AGTGGACTGC CCCAGAAGCC 
ATCCACTTCG GGGTGTTTAC CATCAAGGCT GATGTGTGGT CCTTTGGAGT CTTGCTGATG 
GAGATTGTCA CATATGGGCG TGTTCCCTAC CCAGGAATGA GCAACCCTGA GGTCATCCGT 
AGCCTGGAGC ATGGCTACCG AATGCCATGC CCAGAGACAT GTCCGCCTGA GTTGTACCAT 
GACGTCATCA CTGAGTGCTG GCGAGGCCGA CCTGAGGAGC GGCCTACCTT TGAGTTCCTG 
CAGTCAGTGC TGGAGGACTT CTACACAGCC ACGGAGGGCC AATATGAGCT GCAGCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Blk ( XM_006252188.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252250.1 Rattus norvegicus BLK proto-oncogene, Src family tyrosine kinase (Blk), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa36801
Clone ID Related Accession (Same CDS sequence)	XM_006252188.3
Accession Version	XM_006252188.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1665bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	tyrosine-protein kinase Blk isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252188.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCTCTT GCTGTGCTCG CTCATATAAG ACCTCAAGCT GTGACCTACG ACCTTTGGCT 
GAAGAAGTTT CTACCCCCAA GAGACTCTGG CGCCAGCTTT CCTGGGGACG TGATTCTGCT 
GAGTCTGCTT CTATGCCCTG TGGGCTACTC AGGCTATTCC TGAGGATGGG GCTACTGAGC 
AGCAAGAGGC AGATCAGCGA GAAGAGCAAG AGCTGGAGCC CTGTGAAGGC CCGCGCCCAG 
GGCAAGGTAC CCCCGCCCCT GCCACCCCTG GTTGTCTTCA ACCACCTCCC TCCTCCATCT 
CCTAACCAGC ACCCAGATGA AGAGGAGCGT TTTGTGGTGG CCCTGTTTGA CTATGCCGCT 
GTGAATGACA GGGACCTGCA AGTGCTAAAG GGAGAGAAGC TCCAAGTCTT GAAGAGCACT 
GGAGACTGGT GGTTGGCCAG GTCACTCGTC ACAGGAAGAG AAGGCTATGT GCCCAGCAAC 
TTTGTGGCCC CAGTAGAGAC CCTGGAAGTA GAAAAATGGT TCTTCAGGAC CATTAGCCGG 
AAGGATGCTG AGAGGCAGTT GCTGGCTCCA ATGAACAAAG CCGGCTCCTT TCTCATCAGA 
GAGAGTGAGA GCAATAAAGG TGCCTTTTCC CTATCTGTGA AAGACGTCAC CAGCCAGGGG 
GAGATGGTCA AGCACTATAA GATCCGCTCA CTGGACAATG GAGGCTATTA CATCTCGCCC 
CGGATCACCT TCCCCACCCT CCAGGCCCTG GTGCAGCACT ATTCTGAGAA AGGGGACGGT 
TTGTGTCAGA AGTTGACCCT GCCCTGTGTG AACCCAGCCC CGAAGAATCC CTGGGCCCAA 
GACGAATGGG AAATCCCCAG GCAGTCCCTC AAGTTGGTCC GGAAACTTGG GTCTGGGCAG 
TTTGGTGAAG TCTGGATGGG TTATTACAAA AATAACATGA AGGTGGCAAT CAAGACCCTG 
AAGGAGGGAA CCATGTCTCC GGAAGCTTTC CTGGGTGAGG CCAACGTGAT GAAAACCCTG 
CAGCATGAGA GGCTGGTCCG TCTCTACGCC GTGGTCACCA GAGAGCCCAT CTACATTGTC 
ACGGAATACA TGGCCAGAGG ATGCTTGCTG GATTTTCTGA AGACCGATGA AGGTAGCAGA 
TTGTCCCTTC CAAGGCTGAT TGACATGTCA GCCCAGGTTG CAGAAGGGAT GGCTTACATA 
GAGCGCATGA ATTCCATCCA CCGTGACCTG CGGGCAGCCA ACATCCTGGT GTCTGAGACC 
TTGTGCTGCA AAATCGCTGA CTTCGGCTTG GCCAGGATCA TCGACAGTGA ATATACTGCC 
CAAGAGGGGG CCAAGTTCCC CATCAAGTGG ACTGCCCCAG AAGCCATCCA CTTCGGGGTG 
TTTACCATCA AGGCTGATGT GTGGTCCTTT GGAGTCTTGC TGATGGAGAT TGTCACATAT 
GGGCGTGTTC CCTACCCAGG AATGAGCAAC CCTGAGGTCA TCCGTAGCCT GGAGCATGGC 
TACCGAATGC CATGCCCAGA GACATGTCCG CCTGAGTTGT ACCATGACGT CATCACTGAG 
TGCTGGCGAG GCCGACCTGA GGAGCGGCCT ACCTTTGAGT TCCTGCAGTC AGTGCTGGAG 
GACTTCTACA CAGCCACGGA GGGCCAATAT GAGCTGCAGC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252250.1
CDS	584..2248
Translation	MSSCCARSYKTSSCDLRPLAEEVSTPKRLWRQLSWGRDSAESASMPCGLLRLFLRMGLLSSKRQISEKSKSWSPVKARAQGKVPPPLPPLVVFNHLPPPSPNQHPDEEERFVVALFDYAAVNDRDLQVLKGEKLQVLKSTGDWWLARSLVTGREGYVPSNFVAPVETLEVEKWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDVTSQGEMVKHYKIRSLDNGGYYISPRITFPTLQALVQHYSEKGDGLCQKLTLPCVNPAPKNPWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKTLQHERLVRLYAVVTREPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYHDVITECWRGRPEERPTFEFLQSVLEDFYTATEGQYELQP

Target ORF information:

RefSeq Version	XM_006252188.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BLK proto-oncogene, Src family tyrosine kinase (Blk), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252188.3

ORF Insert Sequence:

ATGAGCTCTT GCTGTGCTCG CTCATATAAG ACCTCAAGCT GTGACCTACG ACCTTTGGCT 
GAAGAAGTTT CTACCCCCAA GAGACTCTGG CGCCAGCTTT CCTGGGGACG TGATTCTGCT 
GAGTCTGCTT CTATGCCCTG TGGGCTACTC AGGCTATTCC TGAGGATGGG GCTACTGAGC 
AGCAAGAGGC AGATCAGCGA GAAGAGCAAG AGCTGGAGCC CTGTGAAGGC CCGCGCCCAG 
GGCAAGGTAC CCCCGCCCCT GCCACCCCTG GTTGTCTTCA ACCACCTCCC TCCTCCATCT 
CCTAACCAGC ACCCAGATGA AGAGGAGCGT TTTGTGGTGG CCCTGTTTGA CTATGCCGCT 
GTGAATGACA GGGACCTGCA AGTGCTAAAG GGAGAGAAGC TCCAAGTCTT GAAGAGCACT 
GGAGACTGGT GGTTGGCCAG GTCACTCGTC ACAGGAAGAG AAGGCTATGT GCCCAGCAAC 
TTTGTGGCCC CAGTAGAGAC CCTGGAAGTA GAAAAATGGT TCTTCAGGAC CATTAGCCGG 
AAGGATGCTG AGAGGCAGTT GCTGGCTCCA ATGAACAAAG CCGGCTCCTT TCTCATCAGA 
GAGAGTGAGA GCAATAAAGG TGCCTTTTCC CTATCTGTGA AAGACGTCAC CAGCCAGGGG 
GAGATGGTCA AGCACTATAA GATCCGCTCA CTGGACAATG GAGGCTATTA CATCTCGCCC 
CGGATCACCT TCCCCACCCT CCAGGCCCTG GTGCAGCACT ATTCTGAGAA AGGGGACGGT 
TTGTGTCAGA AGTTGACCCT GCCCTGTGTG AACCCAGCCC CGAAGAATCC CTGGGCCCAA 
GACGAATGGG AAATCCCCAG GCAGTCCCTC AAGTTGGTCC GGAAACTTGG GTCTGGGCAG 
TTTGGTGAAG TCTGGATGGG TTATTACAAA AATAACATGA AGGTGGCAAT CAAGACCCTG 
AAGGAGGGAA CCATGTCTCC GGAAGCTTTC CTGGGTGAGG CCAACGTGAT GAAAACCCTG 
CAGCATGAGA GGCTGGTCCG TCTCTACGCC GTGGTCACCA GAGAGCCCAT CTACATTGTC 
ACGGAATACA TGGCCAGAGG ATGCTTGCTG GATTTTCTGA AGACCGATGA AGGTAGCAGA 
TTGTCCCTTC CAAGGCTGAT TGACATGTCA GCCCAGGTTG CAGAAGGGAT GGCTTACATA 
GAGCGCATGA ATTCCATCCA CCGTGACCTG CGGGCAGCCA ACATCCTGGT GTCTGAGACC 
TTGTGCTGCA AAATCGCTGA CTTCGGCTTG GCCAGGATCA TCGACAGTGA ATATACTGCC 
CAAGAGGGGG CCAAGTTCCC CATCAAGTGG ACTGCCCCAG AAGCCATCCA CTTCGGGGTG 
TTTACCATCA AGGCTGATGT GTGGTCCTTT GGAGTCTTGC TGATGGAGAT TGTCACATAT 
GGGCGTGTTC CCTACCCAGG AATGAGCAAC CCTGAGGTCA TCCGTAGCCT GGAGCATGGC 
TACCGAATGC CATGCCCAGA GACATGTCCG CCTGAGTTGT ACCATGACGT CATCACTGAG 
TGCTGGCGAG GCCGACCTGA GGAGCGGCCT ACCTTTGAGT TCCTGCAGTC AGTGCTGGAG 
GACTTCTACA CAGCCACGGA GGGCCAATAT GAGCTGCAGC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction.
Proceedings of the National Academy of Sciences of the United States of America106(34)14460-5(2009 Aug)
Borowiec M,Liew CW,Thompson R,Boonyasrisawat W,Hu J,Mlynarski WM,El Khattabi I,Kim SH,Marselli L,Rich SS,Krolewski AS,Bonner-Weir S,Sharma A,Sale M,Mychaleckyj JC,Kulkarni RN,Doria A

Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population.
Arthritis and rheumatism60(2)553-8(2009 Feb)
Ito I,Kawasaki A,Ito S,Hayashi T,Goto D,Matsumoto I,Tsutsumi A,Hom G,Graham RR,Takasaki Y,Hashimoto H,Ohashi J,Behrens TW,Sumida T,Tsuchiya N

The effect of cardiac ischemic preconditioning on rat left ventricular gene expression profile.
Cell biochemistry and function26(2)179-84(2008 Mar-Apr)
Canatan H

[Restoration of the function of bilateral hand grip at the expense of the fingers of the same hand].
Ortopediia travmatologiia i protezirovanie(4)60-5(1977 Apr)
Azolov VV