Arpc5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arpc5
Entrez Gene ID	360854
Full Name	actin related protein 2/3 complex, subunit 5
General protein information	Preferred Names actin related protein 2/3 complex, subunit 5 Names actin-related protein 2/3 complex subunit 5 arp2/3 complex 16 kDa subunit p16-ARC
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q21

mRNA and Protein(s)

mRNA	Protein	Name
NM_001025717.1	NP_001020888.1	actin-related protein 2/3 complex subunit 5

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ARPC5	XP_537159.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008895	XP_319641.4
Xenopus tropicalis (tropical clawed frog)	arpc5	NP_001017242.1
Bos taurus (cattle)	ARPC5	NP_001030524.1
Gallus gallus (chicken)	ARPC5	NP_001026732.1
Drosophila melanogaster (fruit fly)	Arpc5	NP_608693.1
Homo sapiens (human)	ARPC5	NP_005708.1
Mus musculus (house mouse)	Arpc5	NP_080645.2
Caenorhabditis elegans (roundworm)	arx-7	NP_491099.1
Pan troglodytes (chimpanzee)	ARPC5	NP_001233430.1
Rattus norvegicus (Norway rat)	Arpc5	NP_001020888.1
Danio rerio (zebrafish)	arpc5b	NP_958917.1
Danio rerio (zebrafish)	arpc5a	NP_919359.2
Caenorhabditis elegans (roundworm)	C46H11.3	NP_491506.1

Gene Ontology
Bibliography

Related articles in PubMed

Effects of hypothyroidism on expression of CRMP2B and ARPC5 during development of the rat frontal cortex.
Liu CR, Miao J, Zhang YL, Liu YM, Yu BG
International journal of biological sciences9(2)209-18(2013)

Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma.
Kinoshita T, Nohata N, Watanabe-Takano H, Yoshino H, Hidaka H, Fujimura L, Fuse M, Yamasaki T, Enokida H, Nakagawa M, Hanazawa T, Okamoto Y, Seki N
International journal of oncology40(6)1770-8(2012 Jun)

Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma.
Moriya Y, Nohata N, Kinoshita T, Mutallip M, Okamoto T, Yoshida S, Suzuki M, Yoshino I, Seki N
Journal of human genetics57(1)38-45(2012 Jan)

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM
Nature cell biology13(4)383-93(2011 Apr)

[Proteomic changes in cerebral cortex of neonatal rats with experimental congenital hypothyroidism].
Liu CR, Yu BG, Liu YQ, Liu YM, Yang SW, Zhang YL
Zhonghua er ke za zhi = Chinese journal of pediatrics49(3)209-13(2011 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CRMP2B and ARPC5 may participate in CNS injury mediated by hypothyroidism by inducing neurite outgrowth inhibition and cytoskeletal protein disorganization.
Title: Effects of hypothyroidism on expression of CRMP2B and ARPC5 during development of the rat frontal cortex.

Both ARPC5 and RHAMM, in addition to PKC, were required for migration of neointimal smooth muscle cells.
Title: Rear polarization of the microtubule-organizing center in neointimal smooth muscle cells depends on PKC?, ARPC5, and RHAMM.

The following Arpc5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arpc5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07602	NM_001025717.1 Latest version!	Rattus norvegicus actin related protein 2/3 complex, subunit 5 (Arpc5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arpc5 ( NM_001025717.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001020888.1 Rattus norvegicus actin related protein 2/3 complex, subunit 5 (Arpc5), mRNA.

Price & Availability↑

CloneID	ORa07602
Clone ID Related Accession (Same CDS sequence)	NM_001025717.1
Accession Version	NM_001025717.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	actin-related protein 2/3 complex subunit 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC099238.1. On Jul 22, 2005 this sequence version replaced XM_341131.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC099238.1, FQ223037.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCGAAGA ACACGGTGTC GTCGGCCCGC TTCCGGAAGG TGGACGTGGA CGAATATGAT 
GAGAACAAGT TCGTGGACGA GGAGGACGGC GGCGATGGCC AGGCCGGGCC CGACGAGGGC 
GAGGTGGACT CATGCCTACG GCAAGGAAAC ATGACCGCTG CCCTACAGGC CGCTCTGAAA 
AACCCCCCCA TTAACACAAA GAGCCAGGCA GTGAAGGACC GGGCAGGCAG CATCGTCTTG 
AAGGTGCTCA TCTCCTTTAA AGCTAATGAT ATTGAAAAGG CTGTTCAGTC TCTGGACAAG 
AATGGCGTGG ACCTCCTAAT GAAGTATATT TATAAAGGCT TTGAGAGCCC GTCTGACAAT 
AGCAGCGCTA TGTTACTACA GTGGCATGAA AAGGCACTTG CTGCTGGAGG AGTAGGGTCT 
ATCGTTCGTG TTTTGACTGC AAGAAAAACC GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020888.1
CDS	63..518
Translation	MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAMLLQWHEKALAAGGVGSIVRVLTARKTV

Target ORF information:

RefSeq Version	NM_001025717.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus actin related protein 2/3 complex, subunit 5 (Arpc5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025717.1

ORF Insert Sequence:

ATGTCGAAGA ACACGGTGTC GTCGGCCCGC TTCCGGAAGG TGGACGTGGA CGAATATGAT 
GAGAACAAGT TCGTGGACGA GGAGGACGGC GGCGATGGCC AGGCCGGGCC CGACGAGGGC 
GAGGTGGACT CATGCCTACG GCAAGGAAAC ATGACCGCTG CCCTACAGGC CGCTCTGAAA 
AACCCCCCCA TTAACACAAA GAGCCAGGCA GTGAAGGACC GGGCAGGCAG CATCGTCTTG 
AAGGTGCTCA TCTCCTTTAA AGCTAATGAT ATTGAAAAGG CTGTTCAGTC TCTGGACAAG 
AATGGCGTGG ACCTCCTAAT GAAGTATATT TATAAAGGCT TTGAGAGCCC GTCTGACAAT 
AGCAGCGCTA TGTTACTACA GTGGCATGAA AAGGCACTTG CTGCTGGAGG AGTAGGGTCT 
ATCGTTCGTG TTTTGACTGC AAGAAAAACC GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effects of hypothyroidism on expression of CRMP2B and ARPC5 during development of the rat frontal cortex.
International journal of biological sciences9(2)209-18(2013)
Liu CR,Miao J,Zhang YL,Liu YM,Yu BG

Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma.
International journal of oncology40(6)1770-8(2012 Jun)
Kinoshita T,Nohata N,Watanabe-Takano H,Yoshino H,Hidaka H,Fujimura L,Fuse M,Yamasaki T,Enokida H,Nakagawa M,Hanazawa T,Okamoto Y,Seki N

Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma.
Journal of human genetics57(1)38-45(2012 Jan)
Moriya Y,Nohata N,Kinoshita T,Mutallip M,Okamoto T,Yoshida S,Suzuki M,Yoshino I,Seki N

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Nature cell biology13(4)383-93(2011 Apr)
Kuo JC,Han X,Hsiao CT,Yates JR 3rd,Waterman CM

[Proteomic changes in cerebral cortex of neonatal rats with experimental congenital hypothyroidism].
Zhonghua er ke za zhi = Chinese journal of pediatrics49(3)209-13(2011 Mar)
Liu CR,Yu BG,Liu YQ,Liu YM,Yang SW,Zhang YL