Dnai2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dnai2
Entrez Gene ID	360654
Full Name	dynein, axonemal, intermediate chain 2
Synonyms	Dnaic2
General protein information	Preferred Names dynein, axonemal, intermediate chain 2 Names dynein intermediate chain 2, axonemal axonemal dynein intermediate chain 2 dynein, axonemal, intermediate polypeptide 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007726.1	NP_001007727.1	dynein intermediate chain 2, axonemal

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Dnaic2	NP_001030050.2
Gallus gallus (chicken)	DNAI2	XP_415701.2
Drosophila melanogaster (fruit fly)	CG6053	NP_001261723.1
Rattus norvegicus (Norway rat)	Dnai2	NP_001007727.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011539	XP_309969.4
Bos taurus (cattle)	DNAI2	XP_005221385.1
Pan troglodytes (chimpanzee)	DNAI2	XP_003953226.1
Canis lupus familiaris (dog)	DNAI2	XP_540403.3
Danio rerio (zebrafish)	LOC101884977	XP_005156459.1
Homo sapiens (human)	DNAI2	NP_075462.3
	DNAI2	XP_001088046.2
Xenopus tropicalis (tropical clawed frog)	dnai2	XP_002935429.1

Gene Ontology
Bibliography

Related articles in PubMed

ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry.
Hjeij R, Lindstrand A, Francis R, Zariwala MA, Liu X, Li Y, Damerla R, Dougherty GW, Abouhamed M, Olbrich H, Loges NT, Pennekamp P, Davis EE, Carvalho CM, Pehlivan D, Werner C, Raidt J, K?hler G, H?ffner K, Reyes-Mugica M, Lupski JR, Leigh MW, Rosenfeld M, Morgan LC, Knowles MR, Lo CW, Katsanis N, Omran H
American journal of human genetics93(2)357-67(2013 Aug)

Exome sequencing identifies mutations in CCDC114 as a cause of primary ciliary dyskinesia.
Knowles MR, Leigh MW, Ostrowski LE, Huang L, Carson JL, Hazucha MJ, Yin W, Berg JS, Davis SD, Dell SD, Ferkol TW, Rosenfeld M, Sagel SD, Milla CE, Olivier KN, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Shendure J, Zariwala MA,
American journal of human genetics92(1)99-106(2013 Jan)

DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.
Loges NT, Olbrich H, Fenske L, Mussaffi H, Horvath J, Fliegauf M, Kuhl H, Baktai G, Peterffy E, Chodhari R, Chung EM, Rutman A, O'Callaghan C, Blau H, Tiszlavicz L, Voelkel K, Witt M, Zietkiewicz E, Neesen J, Reinhardt R, Mitchison HM, Omran H
American journal of human genetics83(5)547-58(2008 Nov)

Mouse dynein axonemal intermediate chain 2: cloning and expression.
Yang Z, Wu J
DNA and cell biology27(9)479-88(2008 Sep)

The human dynein intermediate chain 2 gene (DNAI2): cloning, mapping, expression pattern, and evaluation as a candidate for primary ciliary dyskinesia.
Pennarun G, Chapelin C, Escudier E, Bridoux AM, Dastot F, Cacheux V, Goossens M, Amselem S, Duriez B
Human genetics107(6)642-9(2000 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dnai2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dnai2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11863	NM_001007726.1 Latest version!	Rattus norvegicus dynein, axonemal, intermediate chain 2 (Dnai2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dnai2 ( NM_001007726.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001007727.1 Rattus norvegicus dynein, axonemal, intermediate chain 2 (Dnai2), mRNA.

Price & Availability↑

CloneID	ORa11863
Clone ID Related Accession (Same CDS sequence)	NM_001007726.1
Accession Version	NM_001007726.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	dynein intermediate chain 2, axonemal
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081920.1. On Nov 29, 2004 this sequence version replaced XM_340931.1. ##Evidence-Data-START## Transcript exon combination :: BC081920.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAGATCG TCTACGTGTA CGTGAAGAAG CGCAGTGAGT TTGGGAAGCA ATGCAACTTC 
TCTGACCGCC AGGCTGAGCT GAACATTGAC ATCTCACCCA ACCCTGAGCT GGCCGCACTG 
TATGTGGAGC GGAACCCAGT GGACACAGGC ATCCAGTGCT CCGCCAGTAT GTCGGAACAT 
GAGGCCAACA CAGAGCGGTT TGAGATGGAG AACTGTGGGG TTAACCACGT CGAGGGGGGC 
TGGCCCAAGG ATGTGAACCC CCAGGAGCTG GAGCAGACCA TCCGCTTCCG GAAGAAAGTG 
GAGAAGGATG AGAATTACAT CAACGCCGTC ATGCAGCTGG GCTCGATCAT GGAGCACTGC 
ATCAAGCAGA ACAATGCCAT CGACATCTAC GAGGAATATT TTGATGACGA GGAGGCCGTG 
GAGGTGACTG AAGAGGCCCC TTCAGCCAAG ACCATCAATG TCTTCAGGGA CCCTCAGGAG 
ATCAAGCGGA CAGCCACACA CCTCTCCTGG CACCCTGATG GTAACAAGAA GCTGGCCGTG 
GCCTATTCCT GCTTGCAGTT CCAGCGCTCG CCCATGGGCA TGAGCCACGA CTCCTACATC 
TGGGACCTGG AAAACCCCAA CCGACCTGAG ATTGCCCTGA AGCCATCGTC TCCTCTCATC 
ACCCTGGAGT ACAACCCTAA GGATTCCCAC GTTCTCCTAG GGGGCTGCTA CAATGGGCAG 
ATAGCCTGCT GGGATACCCG GAAGGGCAGC CTGGTGGCAG AGCTGTCCAC CATTGAGTTC 
AGCCACCGAG ACCCAGTGTA CGGCACCATC TGGTTGCAGT CAAAGACAGG CACCGAGTGC 
TTCTCAGCGT CCACGGATGG GCAGGTCATG TGGTGGGACA TCCGCAAGAT CAGCGAGCCC 
ACCGAAGTTG TCATTATGGA CATCACCAGA AAGGAGCAGC TGGAGAACGC CCTGGGCGCC 
ATCTCCTTGG AGTTCGAGTC TACCTTGCCA ACCAAGTTCA TGGTGGGCAC TGAACAAGGC 
ATTGTCATCT CCTGCAACCG CAAGGCCAAG ACGCCAGCGG AGAAGATCGT TTGCACCTTT 
TCTGGCCACC ACGGCCCTAT CTATGCCCTC CAGAGAAACC CCTTCTACCC AAAGAACTTT 
CTGACTGTTG GCGACTGGGC TGCCCGCATC TGGTCTGAGG AGAGTCGGGA GTCATCTATC 
ATGTGGACCC GGTACCACAT GGCTTACCTC TCTGATGGAG CCTGGAGTCC CGTGAGACCA 
GCGGTTTTCT TCACCACCAA GATGGATGGG ACCCTGGACA TCTGGGACTT GGTGTTCAAG 
CAGTGTGACC CTGCCCTCAG CCTGAAGGTA TGTGACGACC CACTCTTCTG CCTCCGAGTT 
CAGGACACCG GGTGTCTCAT CGCCTGCGGC TCCGAGCTCG GAACAACCAC TCTGCTGGAG 
GTCTCCAGCA GTCTCTCTAC TCTGCAGAGG AATGAGAGGA ACATAGCTTC TTCCATATTT 
GAACGTGAGA CCCGGCGGGA AAAGATCCTA GAGGCCAGAC ACCGCGAGAT GCGGCTGAAG 
GAGAAAGGCA AGGCAGAGGG CAGAGACGAC GACCAGAAGG AGGAGGAGAC AGCCCTGGAC 
CTCGATGAGC TAGTCAACAA AGCCGAGGAG GAGTTCTTCG AAGTCATCTT CGCAGAGCTG 
AAGAGGAAGG AGGCAGAGGC CTTGAAGAAG AAACCGAAAC CTAAAAAAGC AAGTATAGAG 
GTGGAAGGCG AAGATGAGCT GGAAGATATT GCTGGAGAGG AGGAAGAATC CGGCATCATA 
ATGGGTGAAG ATACAGGTGA AGATGACATG GATGAAAAGA ATGAGGGCGG GGCCCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007727.1
CDS	361..2220
Translation	MEIVYVYVKKRSEFGKQCNFSDRQAELNIDISPNPELAALYVERNPVDTGIQCSASMSEHEANTERFEMENCGVNHVEGGWPKDVNPQELEQTIRFRKKVEKDENYINAVMQLGSIMEHCIKQNNAIDIYEEYFDDEEAVEVTEEAPSAKTINVFRDPQEIKRTATHLSWHPDGNKKLAVAYSCLQFQRSPMGMSHDSYIWDLENPNRPEIALKPSSPLITLEYNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIEFSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKISEPTEVVIMDITRKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTPAEKIVCTFSGHHGPIYALQRNPFYPKNFLTVGDWAARIWSEESRESSIMWTRYHMAYLSDGAWSPVRPAVFFTTKMDGTLDIWDLVFKQCDPALSLKVCDDPLFCLRVQDTGCLIACGSELGTTTLLEVSSSLSTLQRNERNIASSIFERETRREKILEARHREMRLKEKGKAEGRDDDQKEEETALDLDELVNKAEEEFFEVIFAELKRKEAEALKKKPKPKKASIEVEGEDELEDIAGEEEESGIIMGEDTGEDDMDEKNEGGAP

Target ORF information:

RefSeq Version	NM_001007726.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dynein, axonemal, intermediate chain 2 (Dnai2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007726.1

ORF Insert Sequence:

ATGGAGATCG TCTACGTGTA CGTGAAGAAG CGCAGTGAGT TTGGGAAGCA ATGCAACTTC 
TCTGACCGCC AGGCTGAGCT GAACATTGAC ATCTCACCCA ACCCTGAGCT GGCCGCACTG 
TATGTGGAGC GGAACCCAGT GGACACAGGC ATCCAGTGCT CCGCCAGTAT GTCGGAACAT 
GAGGCCAACA CAGAGCGGTT TGAGATGGAG AACTGTGGGG TTAACCACGT CGAGGGGGGC 
TGGCCCAAGG ATGTGAACCC CCAGGAGCTG GAGCAGACCA TCCGCTTCCG GAAGAAAGTG 
GAGAAGGATG AGAATTACAT CAACGCCGTC ATGCAGCTGG GCTCGATCAT GGAGCACTGC 
ATCAAGCAGA ACAATGCCAT CGACATCTAC GAGGAATATT TTGATGACGA GGAGGCCGTG 
GAGGTGACTG AAGAGGCCCC TTCAGCCAAG ACCATCAATG TCTTCAGGGA CCCTCAGGAG 
ATCAAGCGGA CAGCCACACA CCTCTCCTGG CACCCTGATG GTAACAAGAA GCTGGCCGTG 
GCCTATTCCT GCTTGCAGTT CCAGCGCTCG CCCATGGGCA TGAGCCACGA CTCCTACATC 
TGGGACCTGG AAAACCCCAA CCGACCTGAG ATTGCCCTGA AGCCATCGTC TCCTCTCATC 
ACCCTGGAGT ACAACCCTAA GGATTCCCAC GTTCTCCTAG GGGGCTGCTA CAATGGGCAG 
ATAGCCTGCT GGGATACCCG GAAGGGCAGC CTGGTGGCAG AGCTGTCCAC CATTGAGTTC 
AGCCACCGAG ACCCAGTGTA CGGCACCATC TGGTTGCAGT CAAAGACAGG CACCGAGTGC 
TTCTCAGCGT CCACGGATGG GCAGGTCATG TGGTGGGACA TCCGCAAGAT CAGCGAGCCC 
ACCGAAGTTG TCATTATGGA CATCACCAGA AAGGAGCAGC TGGAGAACGC CCTGGGCGCC 
ATCTCCTTGG AGTTCGAGTC TACCTTGCCA ACCAAGTTCA TGGTGGGCAC TGAACAAGGC 
ATTGTCATCT CCTGCAACCG CAAGGCCAAG ACGCCAGCGG AGAAGATCGT TTGCACCTTT 
TCTGGCCACC ACGGCCCTAT CTATGCCCTC CAGAGAAACC CCTTCTACCC AAAGAACTTT 
CTGACTGTTG GCGACTGGGC TGCCCGCATC TGGTCTGAGG AGAGTCGGGA GTCATCTATC 
ATGTGGACCC GGTACCACAT GGCTTACCTC TCTGATGGAG CCTGGAGTCC CGTGAGACCA 
GCGGTTTTCT TCACCACCAA GATGGATGGG ACCCTGGACA TCTGGGACTT GGTGTTCAAG 
CAGTGTGACC CTGCCCTCAG CCTGAAGGTA TGTGACGACC CACTCTTCTG CCTCCGAGTT 
CAGGACACCG GGTGTCTCAT CGCCTGCGGC TCCGAGCTCG GAACAACCAC TCTGCTGGAG 
GTCTCCAGCA GTCTCTCTAC TCTGCAGAGG AATGAGAGGA ACATAGCTTC TTCCATATTT 
GAACGTGAGA CCCGGCGGGA AAAGATCCTA GAGGCCAGAC ACCGCGAGAT GCGGCTGAAG 
GAGAAAGGCA AGGCAGAGGG CAGAGACGAC GACCAGAAGG AGGAGGAGAC AGCCCTGGAC 
CTCGATGAGC TAGTCAACAA AGCCGAGGAG GAGTTCTTCG AAGTCATCTT CGCAGAGCTG 
AAGAGGAAGG AGGCAGAGGC CTTGAAGAAG AAACCGAAAC CTAAAAAAGC AAGTATAGAG 
GTGGAAGGCG AAGATGAGCT GGAAGATATT GCTGGAGAGG AGGAAGAATC CGGCATCATA 
ATGGGTGAAG ATACAGGTGA AGATGACATG GATGAAAAGA ATGAGGGCGG GGCCCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry.
American journal of human genetics93(2)357-67(2013 Aug)
Hjeij R,Lindstrand A,Francis R,Zariwala MA,Liu X,Li Y,Damerla R,Dougherty GW,Abouhamed M,Olbrich H,Loges NT,Pennekamp P,Davis EE,Carvalho CM,Pehlivan D,Werner C,Raidt J,K?hler G,H?ffner K,Reyes-Mugica M,Lupski JR,Leigh MW,Rosenfeld M,Morgan LC,Knowles MR,Lo CW,Katsanis N,Omran H

Exome sequencing identifies mutations in CCDC114 as a cause of primary ciliary dyskinesia.
American journal of human genetics92(1)99-106(2013 Jan)
Knowles MR,Leigh MW,Ostrowski LE,Huang L,Carson JL,Hazucha MJ,Yin W,Berg JS,Davis SD,Dell SD,Ferkol TW,Rosenfeld M,Sagel SD,Milla CE,Olivier KN,Turner EH,Lewis AP,Bamshad MJ,Nickerson DA,Shendure J,Zariwala MA,

DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.
American journal of human genetics83(5)547-58(2008 Nov)
Loges NT,Olbrich H,Fenske L,Mussaffi H,Horvath J,Fliegauf M,Kuhl H,Baktai G,Peterffy E,Chodhari R,Chung EM,Rutman A,O'Callaghan C,Blau H,Tiszlavicz L,Voelkel K,Witt M,Zietkiewicz E,Neesen J,Reinhardt R,Mitchison HM,Omran H

Mouse dynein axonemal intermediate chain 2: cloning and expression.
DNA and cell biology27(9)479-88(2008 Sep)
Yang Z,Wu J

The human dynein intermediate chain 2 gene (DNAI2): cloning, mapping, expression pattern, and evaluation as a candidate for primary ciliary dyskinesia.
Human genetics107(6)642-9(2000 Dec)
Pennarun G,Chapelin C,Escudier E,Bridoux AM,Dastot F,Cacheux V,Goossens M,Amselem S,Duriez B