Bmp5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bmp5
Entrez Gene ID	315824
Full Name	bone morphogenetic protein 5
General protein information	Preferred Names bone morphogenetic protein 5 Names bone morphogenetic protein 5
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108168.1	NP_001101638.1	bone morphogenetic protein 5 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Bmp5	NP_001101638.1
Pan troglodytes (chimpanzee)	BMP5	XP_518553.2
	BMP5	XP_001109809.1
Bos taurus (cattle)	BMP5	XP_002697216.1
Mus musculus (house mouse)	Bmp5	NP_031581.2
Xenopus tropicalis (tropical clawed frog)	bmp5	XP_004914553.1
Canis lupus familiaris (dog)	BMP5	XP_532179.2
Gallus gallus (chicken)	BMP5	NP_990479.1
Homo sapiens (human)	BMP5	NP_066551.1
Danio rerio (zebrafish)	bmp5	NP_957345.1

Gene Ontology
Bibliography

Related articles in PubMed

Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.
Palmer K, Fairfield H, Borgeia S, Curtain M, Hassan MG, Dionne L, Yong Karst S, Coombs H, Bronson RT, Reinholdt LG, Bergstrom DE, Donahue LR, Cox TC, Murray SA
Developmental biology415(2)216-227(2016 07)

BMP5 expression in the adult rat brain.
Kusakawa Y, Mikawa S, Sato K
Neuroscience284972-87(2015 Jan)

Bone morphogenetic proteins 2 and 5 are down-regulated in adrenocortical carcinoma and modulate adrenal cell proliferation and steroidogenesis.
Johnsen IK, Kappler R, Auernhammer CJ, Beuschlein F
Cancer research69(14)5784-92(2009 Jul)

Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins.
Nahar NN, Missana LR, Garimella R, Tague SE, Anderson HC
Journal of bone and mineral metabolism26(5)514-9(2008)

BMP-5 expression increases during chondrocyte differentiation in vivo and in vitro and promotes proliferation and cartilage matrix synthesis in primary chondrocyte cultures.
Mailhot G, Yang M, Mason-Savas A, Mackay CA, Leav I, Odgren PR
Journal of cellular physiology214(1)56-64(2008 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results suggest that BMP5 is widely expressed throughout the adult CNS, and this abundant expression in the adult brain strongly supports the idea that BMP5 plays important roles not only in the developing brain but also in the adult brain
Title: BMP5 expression in the adult rat brain.

Bmp5 expression increases during chondrocyte differentiation in vivo and in vitro and promotes cartilage matrix synthesis in primary chondrocyte cultures.
Title: BMP-5 expression increases during chondrocyte differentiation in vivo and in vitro and promotes proliferation and cartilage matrix synthesis in primary chondrocyte cultures.

BMP5 might play a fully paracrine role in rodent ovarian folliculogenesis.
Title: Bone morphogenetic protein 5 expression in the rat ovary: biological effects on granulosa cell proliferation and steroidogenesis.

The following Bmp5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bmp5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06804	NM_001108168.1 Latest version!	Rattus norvegicus bone morphogenetic protein 5 (Bmp5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bmp5 ( NM_001108168.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101638.1 Rattus norvegicus bone morphogenetic protein 5 (Bmp5), mRNA.

Price & Availability↑

CloneID	ORa06804
Clone ID Related Accession (Same CDS sequence)	NM_001108168.1
Accession Version	NM_001108168.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	bone morphogenetic protein 5 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473954.2. On or before Oct 4, 2007 this sequence version replaced XM_236415.4, XM_001059589.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689598, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGCATTGGA CTGTATTTTT ACTTAGGGGT ATTGTGGGCT TCCTCTGGAG CAGCTGGGTT 
CAAGTGGGTT ATGCCAAAGG AGGCTTGGGA GACAATCATG TTCACTCCAG TTTTATTTAT 
AGAAGACTAC GGAACCACGA AAGACGGGAA ATACAGAGGG AAATTCTCTC TATTCTGGGT 
TTGCCTCACA GACCCAGGCC CTTTTCACCG GGGAAGCAAG CATCTTCTGC ACCCCTCTTT 
ATGCTGGATC TGTACAACGC CATGGCCAGC GAAGAAAACC CTGAGGAGTC AGAATATTTA 
GTGAGGGTAT CCCTGGCTGG AGAGGCTAAA GAGACAAGAA AGGGATACCC AGCCTCTCCC 
AATGGGTATG CACATCGTCT GCACTTACCT CCAAGGATTC CTCTGACTAC CCAGAGCCCA 
CCTCTTGCCA GTCTACACGA TACCAATTTT CTGAATGATG CTGACATGGT CATGAGTTTT 
GTCAACCTAG TTGAAAGAGA CAAAGACTTT TCTCATCAGA GAAGGCATTA CAAAGAATTT 
CGGTTTGATC TGACCCAAAT TCCACATGGA GAAGCAGTGA CGGCAGCTGA ATTCCGGATT 
TATAAGGACA AAAGCAACCA TCGGTTTGAA AATGAAACAA TTAAGATTAG CATATATCAG 
ATCATCAAGG AATACACAAA TAGGGACGCA GATCTTTTTC TGCTAGATAC AAGGAAGGCA 
CAAGCTTTAG ATGTGGGTTG GCTTGTCTTT GATATCACCG TGACCAGCAA TCATTGGGTG 
ATTAATCCAC AGAACAATTT GGGCTTACAG CTCTGCGCAG AGACGGGGGA TGGACGCAGC 
ATCAATGTAA AATCTGCCGG TCTCGTGGGA AGACACGGGC CTCAGTCAAA GCAGCCGTTC 
ATGGTGGCCT TCTTCAAGGC AAGTGAGGTT CTTCTTCGAT CTGTGAGAGC AGCCAGCAAA 
CGGAAAAACC AAAACCGCAA TAAATCCAGC TCTCATCAGG ACCCCTCCAG GATTCCCAGT 
GCTGGAGATT ATAATACCAG TGAACAGAAA CAAGCTTGCA AGAAGCACGA GCTCTATGTG 
AGTTTCCGCG ATCTGGGATG GCAGGACTGG ATCATAGCAC CAGAAGGATA TGCCGCATTT 
TATTGCGATG GAGAATGTTC TTTTCCACTT AACGCCCACA TGAATGCCAC TAACCATGCC 
ATAGTCCAGA CTCTGGTACA CCTGATGTTT CCTGACCATG TTCCCAAGCC CTGTTGTGCT 
CCAACCAAAC TAAATGCCAT CTCGGTCCTG TACTTTGATG ACAGCTCCAA TGTAATTTTG 
AAAAAGTACA GAAATATGGT AGTCCGTTCA TGTGGCTGCC ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101638.1
CDS	21..1385
Translation	MHWTVFLLRGIVGFLWSSWVQVGYAKGGLGDNHVHSSFIYRRLRNHERREIQREILSILGLPHRPRPFSPGKQASSAPLFMLDLYNAMASEENPEESEYLVRVSLAGEAKETRKGYPASPNGYAHRLHLPPRIPLTTQSPPLASLHDTNFLNDADMVMSFVNLVERDKDFSHQRRHYKEFRFDLTQIPHGEAVTAAEFRIYKDKSNHRFENETIKISIYQIIKEYTNRDADLFLLDTRKAQALDVGWLVFDITVTSNHWVINPQNNLGLQLCAETGDGRSINVKSAGLVGRHGPQSKQPFMVAFFKASEVLLRSVRAASKRKNQNRNKSSSHQDPSRIPSAGDYNTSEQKQACKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGCH

Target ORF information:

RefSeq Version	NM_001108168.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus bone morphogenetic protein 5 (Bmp5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108168.1

ORF Insert Sequence:

ATGCATTGGA CTGTATTTTT ACTTAGGGGT ATTGTGGGCT TCCTCTGGAG CAGCTGGGTT 
CAAGTGGGTT ATGCCAAAGG AGGCTTGGGA GACAATCATG TTCACTCCAG TTTTATTTAT 
AGAAGACTAC GGAACCACGA AAGACGGGAA ATACAGAGGG AAATTCTCTC TATTCTGGGT 
TTGCCTCACA GACCCAGGCC CTTTTCACCG GGGAAGCAAG CATCTTCTGC ACCCCTCTTT 
ATGCTGGATC TGTACAACGC CATGGCCAGC GAAGAAAACC CTGAGGAGTC AGAATATTTA 
GTGAGGGTAT CCCTGGCTGG AGAGGCTAAA GAGACAAGAA AGGGATACCC AGCCTCTCCC 
AATGGGTATG CACATCGTCT GCACTTACCT CCAAGGATTC CTCTGACTAC CCAGAGCCCA 
CCTCTTGCCA GTCTACACGA TACCAATTTT CTGAATGATG CTGACATGGT CATGAGTTTT 
GTCAACCTAG TTGAAAGAGA CAAAGACTTT TCTCATCAGA GAAGGCATTA CAAAGAATTT 
CGGTTTGATC TGACCCAAAT TCCACATGGA GAAGCAGTGA CGGCAGCTGA ATTCCGGATT 
TATAAGGACA AAAGCAACCA TCGGTTTGAA AATGAAACAA TTAAGATTAG CATATATCAG 
ATCATCAAGG AATACACAAA TAGGGACGCA GATCTTTTTC TGCTAGATAC AAGGAAGGCA 
CAAGCTTTAG ATGTGGGTTG GCTTGTCTTT GATATCACCG TGACCAGCAA TCATTGGGTG 
ATTAATCCAC AGAACAATTT GGGCTTACAG CTCTGCGCAG AGACGGGGGA TGGACGCAGC 
ATCAATGTAA AATCTGCCGG TCTCGTGGGA AGACACGGGC CTCAGTCAAA GCAGCCGTTC 
ATGGTGGCCT TCTTCAAGGC AAGTGAGGTT CTTCTTCGAT CTGTGAGAGC AGCCAGCAAA 
CGGAAAAACC AAAACCGCAA TAAATCCAGC TCTCATCAGG ACCCCTCCAG GATTCCCAGT 
GCTGGAGATT ATAATACCAG TGAACAGAAA CAAGCTTGCA AGAAGCACGA GCTCTATGTG 
AGTTTCCGCG ATCTGGGATG GCAGGACTGG ATCATAGCAC CAGAAGGATA TGCCGCATTT 
TATTGCGATG GAGAATGTTC TTTTCCACTT AACGCCCACA TGAATGCCAC TAACCATGCC 
ATAGTCCAGA CTCTGGTACA CCTGATGTTT CCTGACCATG TTCCCAAGCC CTGTTGTGCT 
CCAACCAAAC TAAATGCCAT CTCGGTCCTG TACTTTGATG ACAGCTCCAA TGTAATTTTG 
AAAAAGTACA GAAATATGGT AGTCCGTTCA TGTGGCTGCC ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.
Developmental biology415(2)216-227(2016 07)
Palmer K,Fairfield H,Borgeia S,Curtain M,Hassan MG,Dionne L,Yong Karst S,Coombs H,Bronson RT,Reinholdt LG,Bergstrom DE,Donahue LR,Cox TC,Murray SA

BMP5 expression in the adult rat brain.
Neuroscience284972-87(2015 Jan)
Kusakawa Y,Mikawa S,Sato K

Bone morphogenetic proteins 2 and 5 are down-regulated in adrenocortical carcinoma and modulate adrenal cell proliferation and steroidogenesis.
Cancer research69(14)5784-92(2009 Jul)
Johnsen IK,Kappler R,Auernhammer CJ,Beuschlein F

Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins.
Journal of bone and mineral metabolism26(5)514-9(2008)
Nahar NN,Missana LR,Garimella R,Tague SE,Anderson HC

BMP-5 expression increases during chondrocyte differentiation in vivo and in vitro and promotes proliferation and cartilage matrix synthesis in primary chondrocyte cultures.
Journal of cellular physiology214(1)56-64(2008 Jan)
Mailhot G,Yang M,Mason-Savas A,Mackay CA,Leav I,Odgren PR

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Bmp5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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