Slc24a4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc24a4
Entrez Gene ID	314396
Full Name	solute carrier family 24 member 4
Synonyms	Nckx4
General protein information	Preferred Names solute carrier family 24 member 4 Names sodium/potassium/calcium exchanger 4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q32

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108051.1	NP_001101521.1	sodium/potassium/calcium exchanger 4
XM_006240471.3	XP_006240533.1	sodium/potassium/calcium exchanger 4 isoform X1
XM_006240472.3	XP_006240534.1	sodium/potassium/calcium exchanger 4 isoform X2

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

STIM1 and SLC24A4 Are Critical for Enamel Maturation.
Wang S, Choi M, Richardson AS, Reid BM, Seymen F, Yildirim M, Tuna E, Gen?ay K, Simmer JP, Hu JC
Journal of dental research93(7 Suppl)94S-100S(2014 Jul)

Identification of mutations in SLC24A4, encoding a potassium-dependent sodium/calcium exchanger, as a cause of amelogenesis imperfecta.
Parry DA, Poulter JA, Logan CV, Brookes SJ, Jafri H, Ferguson CH, Anwari BM, Rashid Y, Zhao H, Johnson CA, Inglehearn CF, Mighell AJ
American journal of human genetics92(2)307-12(2013 Feb)

The Na(+)/Ca(2+) exchanger NCKX4 governs termination and adaptation of the mammalian olfactory response.
Stephan AB, Tobochnik S, Dibattista M, Wall CM, Reisert J, Zhao H
Nature neuroscience15(1)131-7(2011 Nov)

Na+/Ca2+ exchangers: three mammalian gene families control Ca2+ transport.
Lytton J
The Biochemical journal406(3)365-82(2007 Sep)

Novel role for K+-dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle.
Dong H, Jiang Y, Triggle CR, Li X, Lytton J
American journal of physiology. Heart and circulatory physiology291(3)H1226-35(2006 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

mRNA encoding NCKX3 and NCKX4 was demonstrated by RT-PCR and Northern blot in both rat mesenteric and aortic smooth muscle providing evidence for their role in mediating vascular tone.
Title: Novel role for K+-dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle.

The following Slc24a4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc24a4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa11621	NM_001108051.1 Latest version!	Rattus norvegicus solute carrier family 24 member 4 (Slc24a4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa29558	XM_006240471.3 Latest version!	Rattus norvegicus solute carrier family 24 member 4 (Slc24a4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa29559	XM_006240472.3 Latest version!	Rattus norvegicus solute carrier family 24 member 4 (Slc24a4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc24a4 ( NM_001108051.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101521.1 Rattus norvegicus solute carrier family 24 member 4 (Slc24a4), mRNA.

Price & Availability↑

CloneID	ORa11621
Clone ID Related Accession (Same CDS sequence)	NM_001108051.1
Accession Version	NM_001108051.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1113bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	sodium/potassium/calcium exchanger 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473982.1. On or before Oct 4, 2007 this sequence version replaced XM_001066813.1, XM_234470.4. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTTCTACG CCCTGGCCAT CGTGTGTGAT GACTTCTTTG TCCCATCCCT AGAGAAGATC 
TGTGAGAAAC TTCATCTGAG TGAAGATGTG GCGGGTGCCA CCTTCATGGC TGCAGGAAGC 
TCGACACCAG AGCTGTTTGC TTCTGTCATT GGTGTGTTCA TCACCCATGG AGATGTCGGT 
GTAGGAACGA TTGTGGGCTC AGCTGTGTTC AACATCCTAT GTATCATTGG AGTGTGTGGA 
CTCTTTGCTG GACAGGTGGT GCGGTTGACG TGGTGGGCTG TGTGCCGTGA CTCTGTGTAC 
TACACACTCT CTGTCATCGT ACTCATTGCG TTCATATACG ATGAGGAAAT TGTGTGGTAC 
AATATGAAGA TGCAGACGTT TTTCACAACC AAACAAAAGA GCATTGCAAA TGGTAACCCA 
GTCAGCAACG AGCTGGAAGA TGGTAATGAC CTCTATGATG GTAGCTTTGA TGACCCATCT 
GTGCCATTGC TGGGGCAAGA GGCAAAAGGC GACAAGGCTA AGTGGGTGTT CACTTGGCCC 
CTCATCTTCC TCCTGTGCGT CACCATCCCC AACTGCAGCA AGCCTCGCTG GGAGAAGTTC 
TTCATGGTCA CCTTCATCAC GGCCACTCTG TGGATCGCGG TGTTCTCCTA CCTCATGGTG 
TGGCTGGTGA CTATTATTGG ATACACACTT GGGATCCCTG ATGTCATCAT GGGCATCACT 
TTCCTGGCAG CAGGCACGAG TGTCCCAGAC TGCATGGCCA GCTTAATTGT GGCGAGACAA 
GGGCTTGGCG ACATGGCAGT CTCTAACACC ATCGGAAGCA ACGTGTTTGA CATCCTGGTG 
GGGCTTGGCA TCCCATGGGG CCTGCAGACC ATGGTTATTA ATTATGGATC CACAGTGAAG 
ATCAACAGCC GGGGGCTGGT CTATTCCGTG GTGCTGCTGC TGGGCTCTGT GGCTCTCACT 
GTCCTTGGCA TCCACCTCAA CAAATGGCGC CTGGACAGGA AGCTGGGCAT CTACGTGCTG 
GTCCTCTATG CCGTCTTTCT GTGCTTCTCA ATAATGATAG AGTTTAACGT CTTTACCTTC 
GTCAACTTGC CCATGTGCAG AGAAGACGAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101521.1
CDS	586..1698
Translation	MFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWYNMKMQTFFTTKQKSIANGNPVSNELEDGNDLYDGSFDDPSVPLLGQEAKGDKAKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVFTFVNLPMCREDD

Target ORF information:

RefSeq Version	NM_001108051.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 24 member 4 (Slc24a4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108051.1

ORF Insert Sequence:

ATGTTCTACG CCCTGGCCAT CGTGTGTGAT GACTTCTTTG TCCCATCCCT AGAGAAGATC 
TGTGAGAAAC TTCATCTGAG TGAAGATGTG GCGGGTGCCA CCTTCATGGC TGCAGGAAGC 
TCGACACCAG AGCTGTTTGC TTCTGTCATT GGTGTGTTCA TCACCCATGG AGATGTCGGT 
GTAGGAACGA TTGTGGGCTC AGCTGTGTTC AACATCCTAT GTATCATTGG AGTGTGTGGA 
CTCTTTGCTG GACAGGTGGT GCGGTTGACG TGGTGGGCTG TGTGCCGTGA CTCTGTGTAC 
TACACACTCT CTGTCATCGT ACTCATTGCG TTCATATACG ATGAGGAAAT TGTGTGGTAC 
AATATGAAGA TGCAGACGTT TTTCACAACC AAACAAAAGA GCATTGCAAA TGGTAACCCA 
GTCAGCAACG AGCTGGAAGA TGGTAATGAC CTCTATGATG GTAGCTTTGA TGACCCATCT 
GTGCCATTGC TGGGGCAAGA GGCAAAAGGC GACAAGGCTA AGTGGGTGTT CACTTGGCCC 
CTCATCTTCC TCCTGTGCGT CACCATCCCC AACTGCAGCA AGCCTCGCTG GGAGAAGTTC 
TTCATGGTCA CCTTCATCAC GGCCACTCTG TGGATCGCGG TGTTCTCCTA CCTCATGGTG 
TGGCTGGTGA CTATTATTGG ATACACACTT GGGATCCCTG ATGTCATCAT GGGCATCACT 
TTCCTGGCAG CAGGCACGAG TGTCCCAGAC TGCATGGCCA GCTTAATTGT GGCGAGACAA 
GGGCTTGGCG ACATGGCAGT CTCTAACACC ATCGGAAGCA ACGTGTTTGA CATCCTGGTG 
GGGCTTGGCA TCCCATGGGG CCTGCAGACC ATGGTTATTA ATTATGGATC CACAGTGAAG 
ATCAACAGCC GGGGGCTGGT CTATTCCGTG GTGCTGCTGC TGGGCTCTGT GGCTCTCACT 
GTCCTTGGCA TCCACCTCAA CAAATGGCGC CTGGACAGGA AGCTGGGCAT CTACGTGCTG 
GTCCTCTATG CCGTCTTTCT GTGCTTCTCA ATAATGATAG AGTTTAACGT CTTTACCTTC 
GTCAACTTGC CCATGTGCAG AGAAGACGAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc24a4 ( XM_006240471.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006240533.1 Rattus norvegicus solute carrier family 24 member 4 (Slc24a4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa29558
Clone ID Related Accession (Same CDS sequence)	XM_006240471.3
Accession Version	XM_006240471.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1869bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	sodium/potassium/calcium exchanger 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240471.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCTCC GTGGACTCAT CCGGCAGTGC AAAGTTCGCC GGAGGCGAGA GATGCTGCCG 
CAGCAAGTTG GCTTCGTGTG CGCTGTGTTC GCCCTGGTGT GCTGTGCCTC CGGCCTCTTT 
GGAAGCTTGG GCCACAAAAC AGCTTCTGCT GGCAAACACG TTCTGCCAGA CACGTGGCGA 
AATAGAAAGT TGATGGCACC GATAAATGGG ACTCCACTGG CTAAGAACTG CACAGATCCT 
GCGATCCACG AGTTCCCTAC AGACCTGTTC TCCAACAAAG AACGACAGCA TGGCGCTGTC 
CTGCTACACA TCCTTGGTGC ACTCTATATG TTCTACGCCC TGGCCATCGT GTGTGATGAC 
TTCTTTGTCC CATCCCTAGA GAAGATCTGT GAGAAACTTC ATCTGAGTGA AGATGTGGCG 
GGTGCCACCT TCATGGCTGC AGGAAGCTCG ACACCAGAGC TGTTTGCTTC TGTCATTGGT 
GTGTTCATCA CCCATGGAGA TGTCGGTGTA GGAACGATTG TGGGCTCAGC TGTGTTCAAC 
ATCCTATGTA TCATTGGAGT GTGTGGACTC TTTGCTGGAC AGGTGGTGCG GTTGACGTGG 
TGGGCTGTGT GCCGTGACTC TGTGTACTAC ACACTCTCTG TCATCGTACT CATTGCGTTC 
ATATACGATG AGGAAATTGT GTGGTGGGAA GGTCTGATCC TCATCATCTT GTACGTGTTT 
TATATTCTCA TCATGAAGTA CAATATGAAG ATGCAGACGT TTTTCACAAC CAAACAAAAG 
AGCATTGCAA ATGGTAACCC AGTCAGCAAC GAGCTGGAAG ATGGTAATGA CCTCTATGAT 
GGTAGCTTTG ATGACCCATC TGTGCCATTG CTGGGGCAAG TGAAGGAGAA ACCTCCCTAT 
GGCAAGTCCC CCGTGGTGAT GGTGGATGAG ATTCTCAGCT CCAGTCCTCC CAAGTTCACC 
TTCCCTGAGG CTGGCCTGCG CATCATGATC ACCAACAAGT TTGGGCCCAG GACCCGACTA 
CGGATGGCCA GCAGGATCAT AATTAATGAA CGACAGAGGT TGATCAACTC GGCCAATGGT 
GTTAACAGCA AGCCACTGCA AAATGGGAGA CACGAGAACA TGGAGAATGG AAATGTCCCT 
GTAGAGAACC CTGAAGACCC ACAGCAGGGC CAGGAGCAGC AGCCGCCACC ACAGCCGCCA 
CCCCCAGAGC CTGAGTCGGT AGAGACGGTC TTCCTGTCGC CCTTCTCAAT GCCTGAGGCA 
AAAGGCGACA AGGCTAAGTG GGTGTTCACT TGGCCCCTCA TCTTCCTCCT GTGCGTCACC 
ATCCCCAACT GCAGCAAGCC TCGCTGGGAG AAGTTCTTCA TGGTCACCTT CATCACGGCC 
ACTCTGTGGA TCGCGGTGTT CTCCTACCTC ATGGTGTGGC TGGTGACTAT TATTGGATAC 
ACACTTGGGA TCCCTGATGT CATCATGGGC ATCACTTTCC TGGCAGCAGG CACGAGTGTC 
CCAGACTGCA TGGCCAGCTT AATTGTGGCG AGACAAGGGC TTGGCGACAT GGCAGTCTCT 
AACACCATCG GAAGCAACGT GTTTGACATC CTGGTGGGGC TTGGCATCCC ATGGGGCCTG 
CAGACCATGG TTATTAATTA TGGATCCACA GTGAAGATCA ACAGCCGGGG GCTGGTCTAT 
TCCGTGGTGC TGCTGCTGGG CTCTGTGGCT CTCACTGTCC TTGGCATCCA CCTCAACAAA 
TGGCGCCTGG ACAGGAAGCT GGGCATCTAC GTGCTGGTCC TCTATGCCGT CTTTCTGTGC 
TTCTCAATAA TGATAGAGTT TAACGTCTTT ACCTTCGTCA ACTTGCCCAT GTGCAGAGAA 
GACGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006240533.1
CDS	3273..5141
Translation	MALRGLIRQCKVRRRREMLPQQVGFVCAVFALVCCASGLFGSLGHKTASAGKHVLPDTWRNRKLMAPINGTPLAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLILIILYVFYILIMKYNMKMQTFFTTKQKSIANGNPVSNELEDGNDLYDGSFDDPSVPLLGQVKEKPPYGKSPVVMVDEILSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVNSKPLQNGRHENMENGNVPVENPEDPQQGQEQQPPPQPPPPEPESVETVFLSPFSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVFTFVNLPMCREDD

Target ORF information:

RefSeq Version	XM_006240471.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 24 member 4 (Slc24a4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240471.3

ORF Insert Sequence:

ATGGCGCTCC GTGGACTCAT CCGGCAGTGC AAAGTTCGCC GGAGGCGAGA GATGCTGCCG 
CAGCAAGTTG GCTTCGTGTG CGCTGTGTTC GCCCTGGTGT GCTGTGCCTC CGGCCTCTTT 
GGAAGCTTGG GCCACAAAAC AGCTTCTGCT GGCAAACACG TTCTGCCAGA CACGTGGCGA 
AATAGAAAGT TGATGGCACC GATAAATGGG ACTCCACTGG CTAAGAACTG CACAGATCCT 
GCGATCCACG AGTTCCCTAC AGACCTGTTC TCCAACAAAG AACGACAGCA TGGCGCTGTC 
CTGCTACACA TCCTTGGTGC ACTCTATATG TTCTACGCCC TGGCCATCGT GTGTGATGAC 
TTCTTTGTCC CATCCCTAGA GAAGATCTGT GAGAAACTTC ATCTGAGTGA AGATGTGGCG 
GGTGCCACCT TCATGGCTGC AGGAAGCTCG ACACCAGAGC TGTTTGCTTC TGTCATTGGT 
GTGTTCATCA CCCATGGAGA TGTCGGTGTA GGAACGATTG TGGGCTCAGC TGTGTTCAAC 
ATCCTATGTA TCATTGGAGT GTGTGGACTC TTTGCTGGAC AGGTGGTGCG GTTGACGTGG 
TGGGCTGTGT GCCGTGACTC TGTGTACTAC ACACTCTCTG TCATCGTACT CATTGCGTTC 
ATATACGATG AGGAAATTGT GTGGTGGGAA GGTCTGATCC TCATCATCTT GTACGTGTTT 
TATATTCTCA TCATGAAGTA CAATATGAAG ATGCAGACGT TTTTCACAAC CAAACAAAAG 
AGCATTGCAA ATGGTAACCC AGTCAGCAAC GAGCTGGAAG ATGGTAATGA CCTCTATGAT 
GGTAGCTTTG ATGACCCATC TGTGCCATTG CTGGGGCAAG TGAAGGAGAA ACCTCCCTAT 
GGCAAGTCCC CCGTGGTGAT GGTGGATGAG ATTCTCAGCT CCAGTCCTCC CAAGTTCACC 
TTCCCTGAGG CTGGCCTGCG CATCATGATC ACCAACAAGT TTGGGCCCAG GACCCGACTA 
CGGATGGCCA GCAGGATCAT AATTAATGAA CGACAGAGGT TGATCAACTC GGCCAATGGT 
GTTAACAGCA AGCCACTGCA AAATGGGAGA CACGAGAACA TGGAGAATGG AAATGTCCCT 
GTAGAGAACC CTGAAGACCC ACAGCAGGGC CAGGAGCAGC AGCCGCCACC ACAGCCGCCA 
CCCCCAGAGC CTGAGTCGGT AGAGACGGTC TTCCTGTCGC CCTTCTCAAT GCCTGAGGCA 
AAAGGCGACA AGGCTAAGTG GGTGTTCACT TGGCCCCTCA TCTTCCTCCT GTGCGTCACC 
ATCCCCAACT GCAGCAAGCC TCGCTGGGAG AAGTTCTTCA TGGTCACCTT CATCACGGCC 
ACTCTGTGGA TCGCGGTGTT CTCCTACCTC ATGGTGTGGC TGGTGACTAT TATTGGATAC 
ACACTTGGGA TCCCTGATGT CATCATGGGC ATCACTTTCC TGGCAGCAGG CACGAGTGTC 
CCAGACTGCA TGGCCAGCTT AATTGTGGCG AGACAAGGGC TTGGCGACAT GGCAGTCTCT 
AACACCATCG GAAGCAACGT GTTTGACATC CTGGTGGGGC TTGGCATCCC ATGGGGCCTG 
CAGACCATGG TTATTAATTA TGGATCCACA GTGAAGATCA ACAGCCGGGG GCTGGTCTAT 
TCCGTGGTGC TGCTGCTGGG CTCTGTGGCT CTCACTGTCC TTGGCATCCA CCTCAACAAA 
TGGCGCCTGG ACAGGAAGCT GGGCATCTAC GTGCTGGTCC TCTATGCCGT CTTTCTGTGC 
TTCTCAATAA TGATAGAGTT TAACGTCTTT ACCTTCGTCA ACTTGCCCAT GTGCAGAGAA 
GACGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc24a4 ( XM_006240472.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006240534.1 Rattus norvegicus solute carrier family 24 member 4 (Slc24a4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa29559
Clone ID Related Accession (Same CDS sequence)	XM_006240472.3
Accession Version	XM_006240472.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1812bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	sodium/potassium/calcium exchanger 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240472.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCTCC GTGGACTCAT CCGGCAGTGC AAAGTTCGCC GGAGGCGAGA GATGCTGCCG 
CAGCAAGTTG GCTTCGTGTG CGCTGTGTTC GCCCTGGTGT GCTGTGCCTC CGGCCTCTTT 
GGAAGCTTGG GCCACAAAAC AGCTTCTGCT GGCAAACACG TTCTGCCAGA CACGTGGCGA 
AATAGAAAGT TGATGGCACC GATAAATGGG ACTCCACTGG CTAAGAACTG CACAGATCCT 
GCGATCCACG AGTTCCCTAC AGACCTGTTC TCCAACAAAG AACGACAGCA TGGCGCTGTC 
CTGCTACACA TCCTTGGTGC ACTCTATATG TTCTACGCCC TGGCCATCGT GTGTGATGAC 
TTCTTTGTCC CATCCCTAGA GAAGATCTGT GAGAAACTTC ATCTGAGTGA AGATGTGGCG 
GGTGCCACCT TCATGGCTGC AGGAAGCTCG ACACCAGAGC TGTTTGCTTC TGTCATTGGT 
GTGTTCATCA CCCATGGAGA TGTCGGTGTA GGAACGATTG TGGGCTCAGC TGTGTTCAAC 
ATCCTATGTA TCATTGGAGT GTGTGGACTC TTTGCTGGAC AGGTGGTGCG GTTGACGTGG 
TGGGCTGTGT GCCGTGACTC TGTGTACTAC ACACTCTCTG TCATCGTACT CATTGCGTTC 
ATATACGATG AGGAAATTGT GTGGTGGGAA GGTCTGATCC TCATCATCTT GTACGTGTTT 
TATATTCTCA TCATGAAGTA CAATATGAAG ATGCAGACGT TTTTCACAAC CAAACAAAAG 
AGCATTGCAA ATGGTAACCC AGTCAGCAAC GAGCTGGAAG ATGTGAAGGA GAAACCTCCC 
TATGGCAAGT CCCCCGTGGT GATGGTGGAT GAGATTCTCA GCTCCAGTCC TCCCAAGTTC 
ACCTTCCCTG AGGCTGGCCT GCGCATCATG ATCACCAACA AGTTTGGGCC CAGGACCCGA 
CTACGGATGG CCAGCAGGAT CATAATTAAT GAACGACAGA GGTTGATCAA CTCGGCCAAT 
GGTGTTAACA GCAAGCCACT GCAAAATGGG AGACACGAGA ACATGGAGAA TGGAAATGTC 
CCTGTAGAGA ACCCTGAAGA CCCACAGCAG GGCCAGGAGC AGCAGCCGCC ACCACAGCCG 
CCACCCCCAG AGCCTGAGTC GGTAGAGACG GTCTTCCTGT CGCCCTTCTC AATGCCTGAG 
GCAAAAGGCG ACAAGGCTAA GTGGGTGTTC ACTTGGCCCC TCATCTTCCT CCTGTGCGTC 
ACCATCCCCA ACTGCAGCAA GCCTCGCTGG GAGAAGTTCT TCATGGTCAC CTTCATCACG 
GCCACTCTGT GGATCGCGGT GTTCTCCTAC CTCATGGTGT GGCTGGTGAC TATTATTGGA 
TACACACTTG GGATCCCTGA TGTCATCATG GGCATCACTT TCCTGGCAGC AGGCACGAGT 
GTCCCAGACT GCATGGCCAG CTTAATTGTG GCGAGACAAG GGCTTGGCGA CATGGCAGTC 
TCTAACACCA TCGGAAGCAA CGTGTTTGAC ATCCTGGTGG GGCTTGGCAT CCCATGGGGC 
CTGCAGACCA TGGTTATTAA TTATGGATCC ACAGTGAAGA TCAACAGCCG GGGGCTGGTC 
TATTCCGTGG TGCTGCTGCT GGGCTCTGTG GCTCTCACTG TCCTTGGCAT CCACCTCAAC 
AAATGGCGCC TGGACAGGAA GCTGGGCATC TACGTGCTGG TCCTCTATGC CGTCTTTCTG 
TGCTTCTCAA TAATGATAGA GTTTAACGTC TTTACCTTCG TCAACTTGCC CATGTGCAGA 
GAAGACGACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006240534.1
CDS	3270..5081
Translation	MALRGLIRQCKVRRRREMLPQQVGFVCAVFALVCCASGLFGSLGHKTASAGKHVLPDTWRNRKLMAPINGTPLAKNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLILIILYVFYILIMKYNMKMQTFFTTKQKSIANGNPVSNELEDVKEKPPYGKSPVVMVDEILSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVNSKPLQNGRHENMENGNVPVENPEDPQQGQEQQPPPQPPPPEPESVETVFLSPFSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVFTFVNLPMCREDD

Target ORF information:

RefSeq Version	XM_006240472.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 24 member 4 (Slc24a4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240472.3

ORF Insert Sequence:

ATGGCGCTCC GTGGACTCAT CCGGCAGTGC AAAGTTCGCC GGAGGCGAGA GATGCTGCCG 
CAGCAAGTTG GCTTCGTGTG CGCTGTGTTC GCCCTGGTGT GCTGTGCCTC CGGCCTCTTT 
GGAAGCTTGG GCCACAAAAC AGCTTCTGCT GGCAAACACG TTCTGCCAGA CACGTGGCGA 
AATAGAAAGT TGATGGCACC GATAAATGGG ACTCCACTGG CTAAGAACTG CACAGATCCT 
GCGATCCACG AGTTCCCTAC AGACCTGTTC TCCAACAAAG AACGACAGCA TGGCGCTGTC 
CTGCTACACA TCCTTGGTGC ACTCTATATG TTCTACGCCC TGGCCATCGT GTGTGATGAC 
TTCTTTGTCC CATCCCTAGA GAAGATCTGT GAGAAACTTC ATCTGAGTGA AGATGTGGCG 
GGTGCCACCT TCATGGCTGC AGGAAGCTCG ACACCAGAGC TGTTTGCTTC TGTCATTGGT 
GTGTTCATCA CCCATGGAGA TGTCGGTGTA GGAACGATTG TGGGCTCAGC TGTGTTCAAC 
ATCCTATGTA TCATTGGAGT GTGTGGACTC TTTGCTGGAC AGGTGGTGCG GTTGACGTGG 
TGGGCTGTGT GCCGTGACTC TGTGTACTAC ACACTCTCTG TCATCGTACT CATTGCGTTC 
ATATACGATG AGGAAATTGT GTGGTGGGAA GGTCTGATCC TCATCATCTT GTACGTGTTT 
TATATTCTCA TCATGAAGTA CAATATGAAG ATGCAGACGT TTTTCACAAC CAAACAAAAG 
AGCATTGCAA ATGGTAACCC AGTCAGCAAC GAGCTGGAAG ATGTGAAGGA GAAACCTCCC 
TATGGCAAGT CCCCCGTGGT GATGGTGGAT GAGATTCTCA GCTCCAGTCC TCCCAAGTTC 
ACCTTCCCTG AGGCTGGCCT GCGCATCATG ATCACCAACA AGTTTGGGCC CAGGACCCGA 
CTACGGATGG CCAGCAGGAT CATAATTAAT GAACGACAGA GGTTGATCAA CTCGGCCAAT 
GGTGTTAACA GCAAGCCACT GCAAAATGGG AGACACGAGA ACATGGAGAA TGGAAATGTC 
CCTGTAGAGA ACCCTGAAGA CCCACAGCAG GGCCAGGAGC AGCAGCCGCC ACCACAGCCG 
CCACCCCCAG AGCCTGAGTC GGTAGAGACG GTCTTCCTGT CGCCCTTCTC AATGCCTGAG 
GCAAAAGGCG ACAAGGCTAA GTGGGTGTTC ACTTGGCCCC TCATCTTCCT CCTGTGCGTC 
ACCATCCCCA ACTGCAGCAA GCCTCGCTGG GAGAAGTTCT TCATGGTCAC CTTCATCACG 
GCCACTCTGT GGATCGCGGT GTTCTCCTAC CTCATGGTGT GGCTGGTGAC TATTATTGGA 
TACACACTTG GGATCCCTGA TGTCATCATG GGCATCACTT TCCTGGCAGC AGGCACGAGT 
GTCCCAGACT GCATGGCCAG CTTAATTGTG GCGAGACAAG GGCTTGGCGA CATGGCAGTC 
TCTAACACCA TCGGAAGCAA CGTGTTTGAC ATCCTGGTGG GGCTTGGCAT CCCATGGGGC 
CTGCAGACCA TGGTTATTAA TTATGGATCC ACAGTGAAGA TCAACAGCCG GGGGCTGGTC 
TATTCCGTGG TGCTGCTGCT GGGCTCTGTG GCTCTCACTG TCCTTGGCAT CCACCTCAAC 
AAATGGCGCC TGGACAGGAA GCTGGGCATC TACGTGCTGG TCCTCTATGC CGTCTTTCTG 
TGCTTCTCAA TAATGATAGA GTTTAACGTC TTTACCTTCG TCAACTTGCC CATGTGCAGA 
GAAGACGACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

STIM1 and SLC24A4 Are Critical for Enamel Maturation.
Journal of dental research93(7 Suppl)94S-100S(2014 Jul)
Wang S,Choi M,Richardson AS,Reid BM,Seymen F,Yildirim M,Tuna E,Gen?ay K,Simmer JP,Hu JC

Identification of mutations in SLC24A4, encoding a potassium-dependent sodium/calcium exchanger, as a cause of amelogenesis imperfecta.
American journal of human genetics92(2)307-12(2013 Feb)
Parry DA,Poulter JA,Logan CV,Brookes SJ,Jafri H,Ferguson CH,Anwari BM,Rashid Y,Zhao H,Johnson CA,Inglehearn CF,Mighell AJ

The Na(+)/Ca(2+) exchanger NCKX4 governs termination and adaptation of the mammalian olfactory response.
Nature neuroscience15(1)131-7(2011 Nov)
Stephan AB,Tobochnik S,Dibattista M,Wall CM,Reisert J,Zhao H

Na+/Ca2+ exchangers: three mammalian gene families control Ca2+ transport.
The Biochemical journal406(3)365-82(2007 Sep)
Lytton J

Novel role for K+-dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle.
American journal of physiology. Heart and circulatory physiology291(3)H1226-35(2006 Sep)
Dong H,Jiang Y,Triggle CR,Li X,Lytton J