Arhgap21 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arhgap21
Entrez Gene ID	307178
Full Name	Rho GTPase activating protein 21
General protein information	Preferred Names Rho GTPase activating protein 21 Names rho GTPase-activating protein 21
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q12.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001191693.1	NP_001178622.1	rho GTPase-activating protein 21

Pathways from BioSystems

Homologies

	ARHGAP21	XP_001100413.2
Bos taurus (cattle)	ARHGAP21	XP_005214355.1
Gallus gallus (chicken)	ARHGAP21	NP_001170828.1
Canis lupus familiaris (dog)	ARHGAP21	XP_005617050.1
Mus musculus (house mouse)	Arhgap21	NP_001121556.2
Danio rerio (zebrafish)	arhgap21b	XP_005163349.1
Pan troglodytes (chimpanzee)	ARHGAP21	XP_507699.3
Xenopus tropicalis (tropical clawed frog)	arhgap21	NP_001090761.1
Homo sapiens (human)	ARHGAP21	NP_065875.3
Rattus norvegicus (Norway rat)	Arhgap21	NP_001178622.1

Gene Ontology
Bibliography

Related articles in PubMed

CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events.
Schultz ML, Tecedor L, Stein CS, Stamnes MA, Davidson BL
PloS one9(5)e96647(2014)

Cdc42 regulates microtubule-dependent Golgi positioning.
Hehnly H, Xu W, Chen JL, Stamnes M
Traffic (Copenhagen, Denmark)11(8)1067-78(2010 Aug)

ARHGAP21 associates with FAK and PKCzeta and is redistributed after cardiac pressure overload.
Borges L, Bigarella CL, Baratti MO, Crosara-Alberto DP, Joazeiro PP, Franchini KG, Costa FF, Saad ST
Biochemical and biophysical research communications374(4)641-6(2008 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that ARHGAP21 may act as a signaling or scaffold protein of FAK and PKCzeta signaling pathways, developing an important function during cardiac stress.
Title: ARHGAP21 associates with FAK and PKCzeta and is redistributed after cardiac pressure overload.

The following Arhgap21 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arhgap21 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa25610	NM_001191693.1 Latest version!	Rattus norvegicus Rho GTPase activating protein 21 (Arhgap21), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arhgap21 ( NM_001191693.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001178622.1 Rattus norvegicus Rho GTPase activating protein 21 (Arhgap21), mRNA.

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CloneID	ORa25610
Clone ID Related Accession (Same CDS sequence)	NM_001191693.1
Accession Version	NM_001191693.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5859bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-30
Organism	Rattus norvegicus(Norway rat)
Product	rho GTPase-activating protein 21
Comment	Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from AAHX01093275.1, AAHX01093273.1, AAHX01093271.1 and AAHX01093270.1. On Jul 17, 2010 this sequence version replaced XM_225628.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGATGGCCA CACATTGGAC TGGTCTGCCT GAGGGAGATG GTGACAAACT CAAGGCCTGT 
GGAGCCGCCT GTGAGGTGTC AAAAAATAAA GATGGAAAGG AACAGGGTGA ACCCGTGTCA 
CCGTCCGAAG ACGAATCGTT CTCCTGGCCA GGTCCCAAGA CAGTCATGCT GAAGAGAACA 
TCTCAAGGAT TCGGCTTCAC ACTGCGACAC TTCATCGTCT ATCCCCCGGA GTCTGCAATC 
CAGTTCTCAT ACAAGGATGA AGAGAATGGA AACAGAGGAG GAAAGCAAAG GAACCGATTG 
GAGCCGATGG ACACCATATT TGTTAAACAA GTGAAGGAAG GAGGGCCAGC CTTCGAGGCT 
GGGTTATGCA CAGGTGACAG AATTATAAAA GTCAATGGAG AAAGTGTCAT AGGAAAGACC 
TATTCTCAAG TAATTGCTCT CATTCAGAAC AGTGACACCA CACTGGAGCT CAGTGTTATG 
CCAAAGGATG AAGACATTCT CCAAGTGCTA CAGTTTACAA AGGATGTCAC AGCACTGGCG 
TACTCTCAAG ATGCCTACCT GAAAGGCAAC GGAGCTTACA GCGGCAATGC CCGTGACATT 
CCCGAGCCTC CACCAGTTTG CTATCCCTGG CTCCCGGCTA CTCCGTCAGC CACGGCACAG 
CCAGTTGAAG TGTCTCCTCC CGACTCGTTA CTGAATAAAC AGCAAACCAG TACACCAGTC 
CTGACACAAC CGGGCAGGGC CTATAGAATG GAAATACAAG TGCCTCCATC ACCAACAGAT 
GTTGCAAAGT CAAACACGGC CGTGTGTGTT TGCAGTGAGA GTGTGAGGAC CGTCATTGTG 
CCTTCTGAGA AGGTGGTGGA CTTGCTAGCC AATAGAAACA GCCCTTCAGG CCCTGCACAT 
AGAACGGAAG AGGTAAGGTA TGGTGTAAGT GACCAGGCCT CTGCAAAAGC AGCAGCCAGG 
ACCACGCCTC CGCCATCTGC TCCCACTGCC CGTCTGAGTC ATCAGACCAT AGGCTCCAGG 
TCACTGGAAC CTTCTGGAAT TTTACTTAAA TCTGGAAATT ACAGCGGACA TTCAGAAGGA 
ATCTCAAGTA GTAGATCACA AGCTGTGGAT TCTCCCCCTG TGTCTGTCAA TCACTATTCC 
GCAAACTCCC ATCAGCACAT AGACTGGAAA AACTATAAGA CTTACAAAGA ATACATTGAT 
AACAGGAGAT TGCACATAGG TTGTCGGACA ATCCAGGAGA GGTTGGACAG CTTGCGAGCT 
GCATCTCAGA GCGCAGCAGA CTATAACCAG GTGGTGCCCG CCCGCACCGC CCTGCAGGTA 
CGACGTCGAA GCACCTCTCA TGACCGGGTG CCCCAGTCCA TTCAGATCCG GCAGCGCAGT 
GTATCTCAGG AAAGACTGGA AGATTCCGTG CTGATGAAGT ATTGCCCGAG GAGCGCATCT 
CAAGGAGCGC TGACCTCCCC TCCTGTTAGC TTCAGCAACC ATAGAACTCG CTCGTGGGAT 
TACATCGAGG GGCAGAGTGA AGCCACTGCC ACTGTCAATT CTGAAAGTCA GACGCCCGAC 
TCAAACGGGG AACGAAAACA GACTTACAAG TGGAGTGGCT TCACCGAGCA GGATGACCGA 
CGGGGCATTC ATGAGAGACC CAGGCAGCAA GAAATGCACA AACCTTTCCG AGGCTCAAAT 
TTGACTGTGG CCCCCGTTGT TAATTCTGAT AACAGGCGAC TGGGTGGGAG AGGGGTGGGA 
CCTGTTTCAC AGTTTAAAAA AATCCCACCG GACCTAAGAC CACCACATTC CAACAGAAAT 
TTTCCAACCA CGAGTGGGAT GTCACTGCCA CGAGGTATTG CACAAGACAG GTCTCCACTT 
GTGAAAGTCC GAAGTAATTC TCTGAAAGCG CTGCCTCCAC CTGTCCCAAA GCCATCCTTC 
AGCCAGCACT CCCTGGCCTC CACGAAAGAC CAAAGGCCTG TCAACCATCT GCACCAACAC 
GGCCTGCTGA GTCAGCAGAC ACGGGGCCGA CCCGAAAGCA CCTTCCCTCA CCTCGAGCTG 
CAGACCGACG TCTCCCCGAG CTTACCAGGA ACCTCTGCCA AGACCAGTCC TCAGCTCAGT 
GAGAACCTGG GGACGTCAGA CTTAGACTTA CATGCCAGTC CACGGAATGG AGATGTAGAC 
TCACAGGAGG CTGACGTTCA GCCGTCAGAT GTACCAGATA ATAAAGAGTC TGTCATCCTG 
AGAGAGAAAC CTCAGCCTGG CCGCCAGACG CCACAGCCTT TAAGACATCA GTCTTACATC 
TTGGCAGTGA ATGACCAGGA GACCGGGTCA GACCCCACCT GCTGGCTGCC AAATGATGCT 
CGCAGAGAGG TCCACATCAA AAGAATGGAG GAGAGGAAGG CCTCCTGCAC CAGCCCTCCT 
GGCGATTCCC TGGCTTCCAT ACCTTTTATA GACGAACCGA CCAGCCCTAG CATCGACCAC 
GAGGTCGCAC ACATCCCTGC CTCTGCTGTC ATCTCTGCCT CTACCTCCCA GGTCCCCTCC 
ATTGCAACTG TTCCCCCCAG CCTCACCACC TCTGCTCCTC TGATTCGACG TCAGCTCTCC 
CATGACCAAG AATCTGTTGG ACCTCCCAGC CTGGATGGCC AGCACACCTC AAAGACAGAA 
AGATCAAAAT CCTATGATGA AGGCCTGGAT GATTACAGAG AAGACGCAAA GTTATCCTTT 
AAGCACGTGT CTAGCCTGAA GGGAATCAAG ATTGCAGACA GCCAGAAGTC ATCAGAAGAC 
TCTGGGTCCA GAAAGGATTC TTCCTCCGAG GTCTTCAGTG ATGCAGCCAA AGAAGGGTGG 
CTCCAGTTCC GGCCGCTCGT CACCGATAAG GGCAAGAGAG TCGGTGGCAG TATTCGGCCA 
TGGAAACAGA TGTATGTTGT CCTTCGGGGA CATTCACTTT ACTTGTACAA AGACAGACGA 
GAGCAGACGA CGCCATCAGA AGAGGAGCAG CCCATCAGTG TCAACGCTTG CCTGATAGAC 
ATCTCGTACA GTGAGACCAA GAGGAGGAAC GTGTTCCGAC TCACCACGTC CGACTGCGAA 
TGCTTGTTCC AGGCTGAAGA CAGAGACGAT ATGTTAGCAT GGATCAAGAC TATTCAGGAG 
AGTAGCAACC TAAATGAAGA GGACACTGGA GTGACCAACA GAGATCTAAT TAGTCGAAGA 
ATCAAAGAGT ATAACAGTCT GCTGAGCAAA ACAGAACAGT TGCCAAAAAC ACCTCGCCAG 
AGTCTTAGCA TCCGGCAAAC TCTGCTCGGC GCTAAATCAG AGCCAAAGAC TCAAAGCCCA 
CATTCTCCAA AGGAGGAGTC GGAGAGGAAG CTTCTCAGTA AAGATGATAC CAGTCCTCCG 
AAAGACAAAG GTACTTGGAG AAGAGGCATT CCGAGCATCG TGAGGAAGAC GTTTGAGAAA 
AAGCCGGCTG CCACAGGGAC CTTCGGAGTT AGGCTGGACG ATTGCCCGCC TGCCCACACC 
AACCGGTATA TTCCATTAAT CGTTGACATA TGTTGCAAAT TGGTTGAAGA AAGGGGTCTT 
GAATATACAG GTATTTACCG AGTTCCCGGC AACAACGCAG CCATTTCAAG CATGCAGGAA 
GAGCTCAACA AGGGGATGGC AGACATTGAC ATACAAGATG ACAAATGGCG AGATTTGAAT 
GTGATCAGCA GTTTACTAAA ATCCTTCTTC AGAAAGCTCC CCGAGCCTCT CTTTACTAAC 
GACAAATATG CTGACTTCAT CGAGGCCAAT CGCAAGGAGG ACCCTCTAGA TCGGCTGAGG 
ACGCTAAAGA GACTAATTCA CGATCTGCCT GAGCATCATT TCGAGACACT GAAGTTTCTC 
TCGGCCCATC TGAAGACAGT GGCAGAAAAC TCAGAAAAAA ATAAGATGGA ACCCAGAAAC 
CTAGCGATTG TTTTCGGTCC AACTCTAGTG AGAACATCAG AAGACAACAT GACCCACATG 
GTCACACACA TGCCTGACCA GTACAAGATC GTAGAGACCC TCATCCAGCA CCATGACTGG 
TTTTTCACAG AAGAGGGTGC TGAAGAGCCT CTCACAGCAG TGCAGGAGGA GAACACAGTA 
GACTCCCAGC CAGTACCAAA CATAGATCAC TTACTCACCA ACATTGGAAG GACAGGCGTG 
CTCCCTGGAG ATGTATCAGA TTCAGCCACT AGTGACTCGA CAAAATCGAA GGGCTCTTGG 
GGATCGGGGA AGGATCAGTA TAGCAGGGAA CTGCTTGTGT CCTCCATCTT CGCAGCCGCT 
AGTCGCAAGA GGAAAAAGCC CAAAGAGAAA GCCCAGCCCA GCAGCTCGGA AGACGAGCTG 
GACAGTGTGT TCTTTAAGAA GGAGAACATG GAACCGAGTC ACAGTGAGAT TAAAGAAGAG 
TCCAAAAGAG AAAGTGAGAC ACCAGGTAGA AAGCAGAGGG TTGTCGTTGC CAAAGACAGT 
AACACTAAGA AAGACACGGG TACAACGAAG GAGGAGAAGA AGATGCCATC GGACGAACCA 
TCCCCACCAC ACAGCTCCAA ACGCAACAGG TCACCAACGC TCAGCTGTCG CCTGGCCATG 
CTGAAGGAGA GCCCCAGATC ACTTCTGACA CAGAAGCCCC ACTGTGAAGA GACAGGGTCT 
GACTCGGGCA CTCTGTCTTC CCAGGCTTCA CTAGCCAGGT CCTCCACTAA AAAATCCACC 
AGTCCAGAAA CCAGGCACAC TGAGTTTTTG TCCAATGCTG GTACCATCAC CTCAGACTAT 
TCTACCACAT CATCCACTAC CTACTTGACC AGCCTGGACT CCAGCCGCCT GAGCCCTGAG 
GTGCAGTCAG TGGCAGAGAG CAAGGGCGAC GAGGCTGATG ACGAGAGGAG CGAACTGGTG 
AGTGAGGGGC GGCCCGTGGA GACGGACAGT GAGAGCGAGT TCCCGGTGTT CCCCTCCGCC 
CTGACTTCAG GGCAGTTCAG AGGAAAGCTA CAGGAGGTCG CCAGGTCGAG CCGCAGAAAC 
TCGGAAGGCA GTGAAGCCAG CTGCACCGAG GGAAGCCTCA CACCAAGCTT AGACAGCCGC 
AGACAGCAGT TCAGCTCCCA CAGGCTGATC GAATGCGACA CGCTGTCCAG GAAGAAGTCT 
GCTCGCTTCA AGTCGGACAG TGGGAGCCCC GGAGACACCA GGACGGAGAA AGAAACGCCT 
GCCCTGGCCA AGATGTTTGA TGTCATGAAG AAAGGCAAGT CGACGGGGAG CCTCTTGACA 
CCCAGCAGAA GTGAATCCGA AAAGCAGGAG GCCACTTGGA AAACAAAAAT AGCAGATCGC 
TTAAAACTGA GACCCAGGGC ACCCGCAGAT GACATGTTTG GAGTTGGGAA TCAAAAACCT 
ACTGCCGAGA CAGCAAAAAG GAAAAACATC AAACGCAGAC ACACGCTCGG AGGCCACAGA 
GATGCTACAG AAATCAGCGT CCTGAGCTTC TGGAAAGCGC AAGAGCAGAG TGCGGACAAA 
GAGTCCGAAC TTTCAGCTGT GAACCGGTTA AAACCCAAAT GCTCAGCCCA GGACCTCTCC 
ATCTCAGACT GGCTGGCCAG GGAGCGCATC CGCTCCAGCG CCTCCGACCT CAGCCGAAGC 
GAAGGCTGCG AGCCCCAGGC CGAGAGCCCC AGCGTGCTGG GAACACCCAC CAGCACCCAC 
ACACCGCCGC CCTCTCAGCA GCCTGAAGCT AGGGCTGCTG CCAGCACCTC GGCTTCAACC 
AGCCAGCCCC CTCTTTCCAC ACCACCACAG TCACCTGACC AAATAAACGG AGACAGCTTC 
CAGAACACGA GCCAAAATGC TAGTTCTGCG GCCAACGCCC ACCCTCACAA ACTGTCTGAA 
AGTCCCAACA CTAAAACAGA GTCTCCTCCC TGCCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178622.1
CDS	1..5859
Translation	MMATHWTGLPEGDGDKLKACGAACEVSKNKDGKEQGEPVSPSEDESFSWPGPKTVMLKRTSQGFGFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQDAYLKGNGAYSGNARDIPEPPPVCYPWLPATPSATAQPVEVSPPDSLLNKQQTSTPVLTQPGRAYRMEIQVPPSPTDVAKSNTAVCVCSESVRTVIVPSEKVVDLLANRNSPSGPAHRTEEVRYGVSDQASAKAAARTTPPPSAPTARLSHQTIGSRSLEPSGILLKSGNYSGHSEGISSSRSQAVDSPPVSVNHYSANSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSAADYNQVVPARTALQVRRRSTSHDRVPQSIQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPPVSFSNHRTRSWDYIEGQSEATATVNSESQTPDSNGERKQTYKWSGFTEQDDRRGIHERPRQQEMHKPFRGSNLTVAPVVNSDNRRLGGRGVGPVSQFKKIPPDLRPPHSNRNFPTTSGMSLPRGIAQDRSPLVKVRSNSLKALPPPVPKPSFSQHSLASTKDQRPVNHLHQHGLLSQQTRGRPESTFPHLELQTDVSPSLPGTSAKTSPQLSENLGTSDLDLHASPRNGDVDSQEADVQPSDVPDNKESVILREKPQPGRQTPQPLRHQSYILAVNDQETGSDPTCWLPNDARREVHIKRMEERKASCTSPPGDSLASIPFIDEPTSPSIDHEVAHIPASAVISASTSQVPSIATVPPSLTTSAPLIRRQLSHDQESVGPPSLDGQHTSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLQFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKDRREQTTPSEEEQPISVNACLIDISYSETKRRNVFRLTTSDCECLFQAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNSLLSKTEQLPKTPRQSLSIRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRRGIPSIVRKTFEKKPAATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLRTLKRLIHDLPEHHFETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFTEEGAEEPLTAVQEENTVDSQPVPNIDHLLTNIGRTGVLPGDVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDSVFFKKENMEPSHSEIKEESKRESETPGRKQRVVVAKDSNTKKDTGTTKEEKKMPSDEPSPPHSSKRNRSPTLSCRLAMLKESPRSLLTQKPHCEETGSDSGTLSSQASLARSSTKKSTSPETRHTEFLSNAGTITSDYSTTSSTTYLTSLDSSRLSPEVQSVAESKGDEADDERSELVSEGRPVETDSESEFPVFPSALTSGQFRGKLQEVARSSRRNSEGSEASCTEGSLTPSLDSRRQQFSSHRLIECDTLSRKKSARFKSDSGSPGDTRTEKETPALAKMFDVMKKGKSTGSLLTPSRSESEKQEATWKTKIADRLKLRPRAPADDMFGVGNQKPTAETAKRKNIKRRHTLGGHRDATEISVLSFWKAQEQSADKESELSAVNRLKPKCSAQDLSISDWLARERIRSSASDLSRSEGCEPQAESPSVLGTPTSTHTPPPSQQPEARAAASTSASTSQPPLSTPPQSPDQINGDSFQNTSQNASSAANAHPHKLSESPNTKTESPPCL

Target ORF information:

RefSeq Version	NM_001191693.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Rho GTPase activating protein 21 (Arhgap21), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191693.1

ORF Insert Sequence:

ATGATGGCCA CACATTGGAC TGGTCTGCCT GAGGGAGATG GTGACAAACT CAAGGCCTGT 
GGAGCCGCCT GTGAGGTGTC AAAAAATAAA GATGGAAAGG AACAGGGTGA ACCCGTGTCA 
CCGTCCGAAG ACGAATCGTT CTCCTGGCCA GGTCCCAAGA CAGTCATGCT GAAGAGAACA 
TCTCAAGGAT TCGGCTTCAC ACTGCGACAC TTCATCGTCT ATCCCCCGGA GTCTGCAATC 
CAGTTCTCAT ACAAGGATGA AGAGAATGGA AACAGAGGAG GAAAGCAAAG GAACCGATTG 
GAGCCGATGG ACACCATATT TGTTAAACAA GTGAAGGAAG GAGGGCCAGC CTTCGAGGCT 
GGGTTATGCA CAGGTGACAG AATTATAAAA GTCAATGGAG AAAGTGTCAT AGGAAAGACC 
TATTCTCAAG TAATTGCTCT CATTCAGAAC AGTGACACCA CACTGGAGCT CAGTGTTATG 
CCAAAGGATG AAGACATTCT CCAAGTGCTA CAGTTTACAA AGGATGTCAC AGCACTGGCG 
TACTCTCAAG ATGCCTACCT GAAAGGCAAC GGAGCTTACA GCGGCAATGC CCGTGACATT 
CCCGAGCCTC CACCAGTTTG CTATCCCTGG CTCCCGGCTA CTCCGTCAGC CACGGCACAG 
CCAGTTGAAG TGTCTCCTCC CGACTCGTTA CTGAATAAAC AGCAAACCAG TACACCAGTC 
CTGACACAAC CGGGCAGGGC CTATAGAATG GAAATACAAG TGCCTCCATC ACCAACAGAT 
GTTGCAAAGT CAAACACGGC CGTGTGTGTT TGCAGTGAGA GTGTGAGGAC CGTCATTGTG 
CCTTCTGAGA AGGTGGTGGA CTTGCTAGCC AATAGAAACA GCCCTTCAGG CCCTGCACAT 
AGAACGGAAG AGGTAAGGTA TGGTGTAAGT GACCAGGCCT CTGCAAAAGC AGCAGCCAGG 
ACCACGCCTC CGCCATCTGC TCCCACTGCC CGTCTGAGTC ATCAGACCAT AGGCTCCAGG 
TCACTGGAAC CTTCTGGAAT TTTACTTAAA TCTGGAAATT ACAGCGGACA TTCAGAAGGA 
ATCTCAAGTA GTAGATCACA AGCTGTGGAT TCTCCCCCTG TGTCTGTCAA TCACTATTCC 
GCAAACTCCC ATCAGCACAT AGACTGGAAA AACTATAAGA CTTACAAAGA ATACATTGAT 
AACAGGAGAT TGCACATAGG TTGTCGGACA ATCCAGGAGA GGTTGGACAG CTTGCGAGCT 
GCATCTCAGA GCGCAGCAGA CTATAACCAG GTGGTGCCCG CCCGCACCGC CCTGCAGGTA 
CGACGTCGAA GCACCTCTCA TGACCGGGTG CCCCAGTCCA TTCAGATCCG GCAGCGCAGT 
GTATCTCAGG AAAGACTGGA AGATTCCGTG CTGATGAAGT ATTGCCCGAG GAGCGCATCT 
CAAGGAGCGC TGACCTCCCC TCCTGTTAGC TTCAGCAACC ATAGAACTCG CTCGTGGGAT 
TACATCGAGG GGCAGAGTGA AGCCACTGCC ACTGTCAATT CTGAAAGTCA GACGCCCGAC 
TCAAACGGGG AACGAAAACA GACTTACAAG TGGAGTGGCT TCACCGAGCA GGATGACCGA 
CGGGGCATTC ATGAGAGACC CAGGCAGCAA GAAATGCACA AACCTTTCCG AGGCTCAAAT 
TTGACTGTGG CCCCCGTTGT TAATTCTGAT AACAGGCGAC TGGGTGGGAG AGGGGTGGGA 
CCTGTTTCAC AGTTTAAAAA AATCCCACCG GACCTAAGAC CACCACATTC CAACAGAAAT 
TTTCCAACCA CGAGTGGGAT GTCACTGCCA CGAGGTATTG CACAAGACAG GTCTCCACTT 
GTGAAAGTCC GAAGTAATTC TCTGAAAGCG CTGCCTCCAC CTGTCCCAAA GCCATCCTTC 
AGCCAGCACT CCCTGGCCTC CACGAAAGAC CAAAGGCCTG TCAACCATCT GCACCAACAC 
GGCCTGCTGA GTCAGCAGAC ACGGGGCCGA CCCGAAAGCA CCTTCCCTCA CCTCGAGCTG 
CAGACCGACG TCTCCCCGAG CTTACCAGGA ACCTCTGCCA AGACCAGTCC TCAGCTCAGT 
GAGAACCTGG GGACGTCAGA CTTAGACTTA CATGCCAGTC CACGGAATGG AGATGTAGAC 
TCACAGGAGG CTGACGTTCA GCCGTCAGAT GTACCAGATA ATAAAGAGTC TGTCATCCTG 
AGAGAGAAAC CTCAGCCTGG CCGCCAGACG CCACAGCCTT TAAGACATCA GTCTTACATC 
TTGGCAGTGA ATGACCAGGA GACCGGGTCA GACCCCACCT GCTGGCTGCC AAATGATGCT 
CGCAGAGAGG TCCACATCAA AAGAATGGAG GAGAGGAAGG CCTCCTGCAC CAGCCCTCCT 
GGCGATTCCC TGGCTTCCAT ACCTTTTATA GACGAACCGA CCAGCCCTAG CATCGACCAC 
GAGGTCGCAC ACATCCCTGC CTCTGCTGTC ATCTCTGCCT CTACCTCCCA GGTCCCCTCC 
ATTGCAACTG TTCCCCCCAG CCTCACCACC TCTGCTCCTC TGATTCGACG TCAGCTCTCC 
CATGACCAAG AATCTGTTGG ACCTCCCAGC CTGGATGGCC AGCACACCTC AAAGACAGAA 
AGATCAAAAT CCTATGATGA AGGCCTGGAT GATTACAGAG AAGACGCAAA GTTATCCTTT 
AAGCACGTGT CTAGCCTGAA GGGAATCAAG ATTGCAGACA GCCAGAAGTC ATCAGAAGAC 
TCTGGGTCCA GAAAGGATTC TTCCTCCGAG GTCTTCAGTG ATGCAGCCAA AGAAGGGTGG 
CTCCAGTTCC GGCCGCTCGT CACCGATAAG GGCAAGAGAG TCGGTGGCAG TATTCGGCCA 
TGGAAACAGA TGTATGTTGT CCTTCGGGGA CATTCACTTT ACTTGTACAA AGACAGACGA 
GAGCAGACGA CGCCATCAGA AGAGGAGCAG CCCATCAGTG TCAACGCTTG CCTGATAGAC 
ATCTCGTACA GTGAGACCAA GAGGAGGAAC GTGTTCCGAC TCACCACGTC CGACTGCGAA 
TGCTTGTTCC AGGCTGAAGA CAGAGACGAT ATGTTAGCAT GGATCAAGAC TATTCAGGAG 
AGTAGCAACC TAAATGAAGA GGACACTGGA GTGACCAACA GAGATCTAAT TAGTCGAAGA 
ATCAAAGAGT ATAACAGTCT GCTGAGCAAA ACAGAACAGT TGCCAAAAAC ACCTCGCCAG 
AGTCTTAGCA TCCGGCAAAC TCTGCTCGGC GCTAAATCAG AGCCAAAGAC TCAAAGCCCA 
CATTCTCCAA AGGAGGAGTC GGAGAGGAAG CTTCTCAGTA AAGATGATAC CAGTCCTCCG 
AAAGACAAAG GTACTTGGAG AAGAGGCATT CCGAGCATCG TGAGGAAGAC GTTTGAGAAA 
AAGCCGGCTG CCACAGGGAC CTTCGGAGTT AGGCTGGACG ATTGCCCGCC TGCCCACACC 
AACCGGTATA TTCCATTAAT CGTTGACATA TGTTGCAAAT TGGTTGAAGA AAGGGGTCTT 
GAATATACAG GTATTTACCG AGTTCCCGGC AACAACGCAG CCATTTCAAG CATGCAGGAA 
GAGCTCAACA AGGGGATGGC AGACATTGAC ATACAAGATG ACAAATGGCG AGATTTGAAT 
GTGATCAGCA GTTTACTAAA ATCCTTCTTC AGAAAGCTCC CCGAGCCTCT CTTTACTAAC 
GACAAATATG CTGACTTCAT CGAGGCCAAT CGCAAGGAGG ACCCTCTAGA TCGGCTGAGG 
ACGCTAAAGA GACTAATTCA CGATCTGCCT GAGCATCATT TCGAGACACT GAAGTTTCTC 
TCGGCCCATC TGAAGACAGT GGCAGAAAAC TCAGAAAAAA ATAAGATGGA ACCCAGAAAC 
CTAGCGATTG TTTTCGGTCC AACTCTAGTG AGAACATCAG AAGACAACAT GACCCACATG 
GTCACACACA TGCCTGACCA GTACAAGATC GTAGAGACCC TCATCCAGCA CCATGACTGG 
TTTTTCACAG AAGAGGGTGC TGAAGAGCCT CTCACAGCAG TGCAGGAGGA GAACACAGTA 
GACTCCCAGC CAGTACCAAA CATAGATCAC TTACTCACCA ACATTGGAAG GACAGGCGTG 
CTCCCTGGAG ATGTATCAGA TTCAGCCACT AGTGACTCGA CAAAATCGAA GGGCTCTTGG 
GGATCGGGGA AGGATCAGTA TAGCAGGGAA CTGCTTGTGT CCTCCATCTT CGCAGCCGCT 
AGTCGCAAGA GGAAAAAGCC CAAAGAGAAA GCCCAGCCCA GCAGCTCGGA AGACGAGCTG 
GACAGTGTGT TCTTTAAGAA GGAGAACATG GAACCGAGTC ACAGTGAGAT TAAAGAAGAG 
TCCAAAAGAG AAAGTGAGAC ACCAGGTAGA AAGCAGAGGG TTGTCGTTGC CAAAGACAGT 
AACACTAAGA AAGACACGGG TACAACGAAG GAGGAGAAGA AGATGCCATC GGACGAACCA 
TCCCCACCAC ACAGCTCCAA ACGCAACAGG TCACCAACGC TCAGCTGTCG CCTGGCCATG 
CTGAAGGAGA GCCCCAGATC ACTTCTGACA CAGAAGCCCC ACTGTGAAGA GACAGGGTCT 
GACTCGGGCA CTCTGTCTTC CCAGGCTTCA CTAGCCAGGT CCTCCACTAA AAAATCCACC 
AGTCCAGAAA CCAGGCACAC TGAGTTTTTG TCCAATGCTG GTACCATCAC CTCAGACTAT 
TCTACCACAT CATCCACTAC CTACTTGACC AGCCTGGACT CCAGCCGCCT GAGCCCTGAG 
GTGCAGTCAG TGGCAGAGAG CAAGGGCGAC GAGGCTGATG ACGAGAGGAG CGAACTGGTG 
AGTGAGGGGC GGCCCGTGGA GACGGACAGT GAGAGCGAGT TCCCGGTGTT CCCCTCCGCC 
CTGACTTCAG GGCAGTTCAG AGGAAAGCTA CAGGAGGTCG CCAGGTCGAG CCGCAGAAAC 
TCGGAAGGCA GTGAAGCCAG CTGCACCGAG GGAAGCCTCA CACCAAGCTT AGACAGCCGC 
AGACAGCAGT TCAGCTCCCA CAGGCTGATC GAATGCGACA CGCTGTCCAG GAAGAAGTCT 
GCTCGCTTCA AGTCGGACAG TGGGAGCCCC GGAGACACCA GGACGGAGAA AGAAACGCCT 
GCCCTGGCCA AGATGTTTGA TGTCATGAAG AAAGGCAAGT CGACGGGGAG CCTCTTGACA 
CCCAGCAGAA GTGAATCCGA AAAGCAGGAG GCCACTTGGA AAACAAAAAT AGCAGATCGC 
TTAAAACTGA GACCCAGGGC ACCCGCAGAT GACATGTTTG GAGTTGGGAA TCAAAAACCT 
ACTGCCGAGA CAGCAAAAAG GAAAAACATC AAACGCAGAC ACACGCTCGG AGGCCACAGA 
GATGCTACAG AAATCAGCGT CCTGAGCTTC TGGAAAGCGC AAGAGCAGAG TGCGGACAAA 
GAGTCCGAAC TTTCAGCTGT GAACCGGTTA AAACCCAAAT GCTCAGCCCA GGACCTCTCC 
ATCTCAGACT GGCTGGCCAG GGAGCGCATC CGCTCCAGCG CCTCCGACCT CAGCCGAAGC 
GAAGGCTGCG AGCCCCAGGC CGAGAGCCCC AGCGTGCTGG GAACACCCAC CAGCACCCAC 
ACACCGCCGC CCTCTCAGCA GCCTGAAGCT AGGGCTGCTG CCAGCACCTC GGCTTCAACC 
AGCCAGCCCC CTCTTTCCAC ACCACCACAG TCACCTGACC AAATAAACGG AGACAGCTTC 
CAGAACACGA GCCAAAATGC TAGTTCTGCG GCCAACGCCC ACCCTCACAA ACTGTCTGAA 
AGTCCCAACA CTAAAACAGA GTCTCCTCCC TGCCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events.
PloS one9(5)e96647(2014)
Schultz ML,Tecedor L,Stein CS,Stamnes MA,Davidson BL

Cdc42 regulates microtubule-dependent Golgi positioning.
Traffic (Copenhagen, Denmark)11(8)1067-78(2010 Aug)
Hehnly H,Xu W,Chen JL,Stamnes M

ARHGAP21 associates with FAK and PKCzeta and is redistributed after cardiac pressure overload.
Biochemical and biophysical research communications374(4)641-6(2008 Oct)
Borges L,Bigarella CL,Baratti MO,Crosara-Alberto DP,Joazeiro PP,Franchini KG,Costa FF,Saad ST

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Arhgap21 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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