Mrm2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mrm2
Entrez Gene ID	304323
Full Name	mitochondrial rRNA methyltransferase 2
Synonyms	Ftsj2
General protein information	Preferred Names mitochondrial rRNA methyltransferase 2 Names rRNA methyltransferase 2, mitochondrial FtsJ RNA methyltransferase homolog 2 FtsJ homolog 2 putative ribosomal RNA methyltransferase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107125.1	NP_001100595.1	rRNA methyltransferase 2, mitochondrial

Pathways from BioSystems

Homologies

Homo sapiens (human)	FTSJ2	NP_037525.1
Danio rerio (zebrafish)	LOC555586	XP_683228.2
Saccharomyces cerevisiae (baker's yeast)	MRM2	NP_011379.1
Pan troglodytes (chimpanzee)	FTSJ2	XP_003318261.1
Bos taurus (cattle)	FTSJ2	NP_001178187.1
Rattus norvegicus (Norway rat)	Ftsj2	NP_001100595.1
Gallus gallus (chicken)	FTSJ2	NP_001264474.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP013223	XP_003436733.1
Caenorhabditis elegans (roundworm)	F45G2.9	NP_499776.1
Kluyveromyces lactis	KLLA0B01980g	XP_451619.1
Drosophila melanogaster (fruit fly)	CG11447	NP_650835.1
Eremothecium gossypii	AGOS_AFL117C	NP_985433.2
Magnaporthe oryzae (rice blast fungus)	MGG_04502	XP_003710953.1
Canis lupus familiaris (dog)	FTSJ2	XP_003434808.1
Xenopus tropicalis (tropical clawed frog)	ftsj2	XP_002944869.1
	FTSJ2	XP_001086161.1
Mus musculus (house mouse)	Ftsj2	NP_080786.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004177	XP_313065.4

Gene Ontology
Bibliography

Related articles in PubMed

Assignment of 2'-O-methyltransferases to modification sites on the mammalian mitochondrial large subunit 16 S ribosomal RNA (rRNA).
Lee KW, Bogenhagen DF
The Journal of biological chemistry289(36)24936-42(2014 Sep)

Identification and characterization of FTSJ2, a novel human nucleolar protein homologous to bacterial ribosomal RNA methyltransferase.
Ching YP, Zhou HJ, Yuan JG, Qiang BQ, Kung Hf HF, Jin DY
Genomics79(1)2-6(2002 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Mrm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mrm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02967	NM_001107125.1 Latest version!	Rattus norvegicus mitochondrial rRNA methyltransferase 2 (Mrm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mrm2 ( NM_001107125.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100595.1 Rattus norvegicus mitochondrial rRNA methyltransferase 2 (Mrm2), mRNA.

Price & Availability↑

CloneID	ORa02967
Clone ID Related Accession (Same CDS sequence)	NM_001107125.1
Accession Version	NM_001107125.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	rRNA methyltransferase 2, mitochondrial
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474012.1. On or before Oct 4, 2007 this sequence version replaced XM_221949.4, XM_001073997.1. ##Evidence-Data-START## Transcript exon combination :: CB790613.1, EV768778.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGACTGGGT ATCCGAAGCT GGTAGGCGTT CCCCTTAAGG TTCGGAGGTT ACACACAGCA 
GTGTGTCACT ACAAGGGCCG GACAGGCGCC GAGCACCTGT GGTTGATGCG CCATCTAAAG 
GACCCGTTTG TGAAGGCCGC AAAGGCGGAG AGTTACCGCT GCCGCAGCGC CTTCAAGCTC 
CTGGAGATGA ATGAGAAGCA TCACATCCTG AGGCCTGGGC TCCGGGTGCT GGACTGCGGG 
GCAGCTCCCG GGGCCTGGAG TCAGGTGGCA GTGCAGAGCG TCAACGCCAC AGGAGCAGAT 
TCCAGCTCTC CCATGGGCTT CGTGCTCGGG GTCGATCTTC TTCACATGTT CCCTTTGGCA 
GGAGCAACTT TTCTGTGCCC TGCTGATGTG ACTGACCCCA GAACTTTCCA GAGAATTTTA 
GAACTGCTTC CCAGAAGGAG AGCGGATGTG ATTCTGAGTG ACATGGCACC GAATGCCACT 
GGGATCCGAG ACCTTGATCA TGACAGGCTC ATAAGCTTGT GCCTTACCCT TGTGGACATG 
GCTGTGGACA TCCTGCACCC CGGGGGGACA CTGCTGTGTA AAACCTGGGC CGGAAGTAAA 
AGCCACCTGC TGCAGAAGAG ACTAGCCCAG GAATTCCGAA GCACAAGGGT CGTGAAACCG 
GAGGCTAGCA GGAAAGAGTC CGCAGAGGTC TATCTGTTAG CCACACAGTA CCATGGGAGG 
AAGGGCTCCA CCAAGCAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100595.1
CDS	43..783
Translation	MTGYPKLVGVPLKVRRLHTAVCHYKGRTGAEHLWLMRHLKDPFVKAAKAESYRCRSAFKLLEMNEKHHILRPGLRVLDCGAAPGAWSQVAVQSVNATGADSSSPMGFVLGVDLLHMFPLAGATFLCPADVTDPRTFQRILELLPRRRADVILSDMAPNATGIRDLDHDRLISLCLTLVDMAVDILHPGGTLLCKTWAGSKSHLLQKRLAQEFRSTRVVKPEASRKESAEVYLLATQYHGRKGSTKQ

Target ORF information:

RefSeq Version	NM_001107125.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mitochondrial rRNA methyltransferase 2 (Mrm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107125.1

ORF Insert Sequence:

ATGACTGGGT ATCCGAAGCT GGTAGGCGTT CCCCTTAAGG TTCGGAGGTT ACACACAGCA 
GTGTGTCACT ACAAGGGCCG GACAGGCGCC GAGCACCTGT GGTTGATGCG CCATCTAAAG 
GACCCGTTTG TGAAGGCCGC AAAGGCGGAG AGTTACCGCT GCCGCAGCGC CTTCAAGCTC 
CTGGAGATGA ATGAGAAGCA TCACATCCTG AGGCCTGGGC TCCGGGTGCT GGACTGCGGG 
GCAGCTCCCG GGGCCTGGAG TCAGGTGGCA GTGCAGAGCG TCAACGCCAC AGGAGCAGAT 
TCCAGCTCTC CCATGGGCTT CGTGCTCGGG GTCGATCTTC TTCACATGTT CCCTTTGGCA 
GGAGCAACTT TTCTGTGCCC TGCTGATGTG ACTGACCCCA GAACTTTCCA GAGAATTTTA 
GAACTGCTTC CCAGAAGGAG AGCGGATGTG ATTCTGAGTG ACATGGCACC GAATGCCACT 
GGGATCCGAG ACCTTGATCA TGACAGGCTC ATAAGCTTGT GCCTTACCCT TGTGGACATG 
GCTGTGGACA TCCTGCACCC CGGGGGGACA CTGCTGTGTA AAACCTGGGC CGGAAGTAAA 
AGCCACCTGC TGCAGAAGAG ACTAGCCCAG GAATTCCGAA GCACAAGGGT CGTGAAACCG 
GAGGCTAGCA GGAAAGAGTC CGCAGAGGTC TATCTGTTAG CCACACAGTA CCATGGGAGG 
AAGGGCTCCA CCAAGCAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Assignment of 2'-O-methyltransferases to modification sites on the mammalian mitochondrial large subunit 16 S ribosomal RNA (rRNA).
The Journal of biological chemistry289(36)24936-42(2014 Sep)
Lee KW,Bogenhagen DF

Identification and characterization of FTSJ2, a novel human nucleolar protein homologous to bacterial ribosomal RNA methyltransferase.
Genomics79(1)2-6(2002 Jan)
Ching YP,Zhou HJ,Yuan JG,Qiang BQ,Kung Hf HF,Jin DY