Rab21 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rab21
Entrez Gene ID	299799
Full Name	RAB21, member RAS oncogene family
General protein information	Preferred Names RAB21, member RAS oncogene family Names ras-related protein Rab-21
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q22
Summary	human homolog may play a role in vesicle-mediated transport in polarized intestinal cells [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004238.1	NP_001004238.1	ras-related protein Rab-21

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RAB21	XP_522469.2
	LOC718715	XP_001117520.1
Rattus norvegicus (Norway rat)	Rab21	NP_001004238.1
Danio rerio (zebrafish)	zgc:154045	NP_001070133.1
Mus musculus (house mouse)	Rab21	NP_077774.1
Gallus gallus (chicken)	RAB21	XP_001233648.1
Drosophila melanogaster (fruit fly)	Rab21	NP_001259785.1
Caenorhabditis elegans (roundworm)	rab-21	NP_495854.1
Homo sapiens (human)	RAB21	NP_055814.1
Canis lupus familiaris (dog)	RAB21	XP_003431485.2
Oryza sativa (rice)	Os05g0341600	NP_001055247.1
Xenopus tropicalis (tropical clawed frog)	rab21	NP_001016319.1

Gene Ontology
Bibliography

Related articles in PubMed

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kr?hnert K, Sch?fer C, Rammner B, Koo SJ, Cla?en GA, Krauss M, Haucke V, Urlaub H, Rizzoli SO
Science (New York, N.Y.)344(6187)1023-8(2014 May)

A molecular network for the transport of the TI-VAMP/VAMP7 vesicles from cell center to periphery.
Burgo A, Proux-Gillardeaux V, Sotirakis E, Bun P, Casano A, Verraes A, Liem RK, Formstecher E, Coppey-Moisan M, Galli T
Developmental cell23(1)166-80(2012 Jul)

The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes.
Ohbayashi N, Yatsu A, Tamura K, Fukuda M
Molecular biology of the cell23(4)669-78(2012 Feb)

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM
Nature cell biology13(4)383-93(2011 Apr)

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.
Yoshimura S, Gerondopoulos A, Linford A, Rigden DJ, Barr FA
The Journal of cell biology191(2)367-81(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Rab21 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rab21 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10188	NM_001004238.1 Latest version!	Rattus norvegicus RAB21, member RAS oncogene family (Rab21), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rab21 ( NM_001004238.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001004238.1 Rattus norvegicus RAB21, member RAS oncogene family (Rab21), mRNA.

Price & Availability↑

CloneID	ORa10188
Clone ID Related Accession (Same CDS sequence)	NM_001004238.1
Accession Version	NM_001004238.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Rattus norvegicus(Norway rat)
Product	ras-related protein Rab-21
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079323.1. On Sep 10, 2004 this sequence version replaced XM_216895.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079323.1, CF111792.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGCGG CCGGCGGCGG GGCGGCGGCG GCGGCGGGCC GAGCCTACTC TTTTAAGGTG 
GTGCTGCTCG GAGAAGGCTG CGTGGGGAAG ACGTCGCTGG TGCTGCGCTA CTGCGAGAAC 
AAGTTCAACG ACAAGCACAT CACCACCCTG CAGGCTTCTT TCTTAACAAA GAAGTTAAAT 
ATTGGTGGGA AGAGAGTAAA CCTTGCTATA TGGGATACAG CCGGTCAAGA GAGATTCCAT 
GCATTGGGTC CAATTTACTA CCGAGATTCG AATGGAGCTA TTTTAGTTTA TGATGTAACA 
GATGAAGATT CTTTTCAGAA GGTAAAAAAC TGGGTCAAAG AATTACGGAA AATGTTGGGA 
AATGAAATCT GTTTGTGTAT AGTTGGTAAT AAAATAGACT TGGAAAAGGA GAGGCACGTC 
TCCATTCAAG AAGCAGAATC GTATGCAGAG TCTGTGGGAG CAAAGCATTA CCATACTTCT 
GCTAAACAAA ACAAAGGCAT TGAGGAACTC TTTCTTGACC TTTGTAAAAG GATGATAGAA 
ACGGCCCAGG TGGATGAGAG GGCGAAGGGC AATGGCTCGA GTCAAGCAGG GGCTGCGAGG 
CGCGGCGTGC AGATCATCGA CGACGAACCT CAAGCCCAGA GTGGCAGTGG AGGGTGCTGT 
TCTTCTGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004238.1
CDS	221..892
Translation	MAAAGGGAAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQAGAARRGVQIIDDEPQAQSGSGGCCSSG

Target ORF information:

RefSeq Version	NM_001004238.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RAB21, member RAS oncogene family (Rab21), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004238.1

ORF Insert Sequence:

ATGGCTGCGG CCGGCGGCGG GGCGGCGGCG GCGGCGGGCC GAGCCTACTC TTTTAAGGTG 
GTGCTGCTCG GAGAAGGCTG CGTGGGGAAG ACGTCGCTGG TGCTGCGCTA CTGCGAGAAC 
AAGTTCAACG ACAAGCACAT CACCACCCTG CAGGCTTCTT TCTTAACAAA GAAGTTAAAT 
ATTGGTGGGA AGAGAGTAAA CCTTGCTATA TGGGATACAG CCGGTCAAGA GAGATTCCAT 
GCATTGGGTC CAATTTACTA CCGAGATTCG AATGGAGCTA TTTTAGTTTA TGATGTAACA 
GATGAAGATT CTTTTCAGAA GGTAAAAAAC TGGGTCAAAG AATTACGGAA AATGTTGGGA 
AATGAAATCT GTTTGTGTAT AGTTGGTAAT AAAATAGACT TGGAAAAGGA GAGGCACGTC 
TCCATTCAAG AAGCAGAATC GTATGCAGAG TCTGTGGGAG CAAAGCATTA CCATACTTCT 
GCTAAACAAA ACAAAGGCAT TGAGGAACTC TTTCTTGACC TTTGTAAAAG GATGATAGAA 
ACGGCCCAGG TGGATGAGAG GGCGAAGGGC AATGGCTCGA GTCAAGCAGG GGCTGCGAGG 
CGCGGCGTGC AGATCATCGA CGACGAACCT CAAGCCCAGA GTGGCAGTGG AGGGTGCTGT 
TCTTCTGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Science (New York, N.Y.)344(6187)1023-8(2014 May)
Wilhelm BG,Mandad S,Truckenbrodt S,Kr?hnert K,Sch?fer C,Rammner B,Koo SJ,Cla?en GA,Krauss M,Haucke V,Urlaub H,Rizzoli SO

A molecular network for the transport of the TI-VAMP/VAMP7 vesicles from cell center to periphery.
Developmental cell23(1)166-80(2012 Jul)
Burgo A,Proux-Gillardeaux V,Sotirakis E,Bun P,Casano A,Verraes A,Liem RK,Formstecher E,Coppey-Moisan M,Galli T

The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes.
Molecular biology of the cell23(4)669-78(2012 Feb)
Ohbayashi N,Yatsu A,Tamura K,Fukuda M

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Nature cell biology13(4)383-93(2011 Apr)
Kuo JC,Han X,Hsiao CT,Yates JR 3rd,Waterman CM

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.
The Journal of cell biology191(2)367-81(2010 Oct)
Yoshimura S,Gerondopoulos A,Linford A,Rigden DJ,Barr FA