LOC299282 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	LOC299282
Entrez Gene ID	299282
Full Name	Serine protease inhibitor
Synonyms	Ab1-021,CPi-23,SPI1,Serpina3l,Spin1,Spin2a
General protein information	Preferred Names Serine protease inhibitor Names Serine protease inhibitor SPI-1 SPI-2.1 contrapsin-like protease inhibitor 3 contrapsin-like protease inhibitor-related protein liver regeneration protein lrryan serine protease inhibitor 1 serine protease inhibitor 2.1 serine protease inhibitor 2a serine protease inhibitor A3L serpin A3L
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q32
Summary	may act as a serine protease inhibitor; may play a role in inflammatory response [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_182474.1	NP_872280.1	Serine protease inhibitor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Expression patterns of murine antichymotrypsin-like genes reflect evolutionary divergence at the Serpina3 locus.
Horvath AJ, Forsyth SL, Coughlin PB
Journal of molecular evolution59(4)488-97(2004 Oct)

Molecular cloning and characterization of rat contrapsin-like protease inhibitor and related proteins.
Ohkubo K, Ogata S, Misumi Y, Takami N, Ikehara Y
Journal of biochemistry109(2)243-50(1991 Feb)

Primary structure and assignment to chromosome 6 of three related rat genes encoding liver serine protease inhibitors.
Pag?s G, Rouayrenc JF, Rossi V, Le Cam G, Mariller M, Szpirer J, Szpirer C, Levan G, Le Cam A
Gene94(2)273-82(1990 Oct)

Accelerated evolution in the reactive centre regions of serine protease inhibitors.
Hill RE, Hastie ND
Nature326(6108)96-9(1987 Mar 5-11)

Growth hormone induces two mRNA species of the serine protease inhibitor gene family in rat liver.
Yoon JB, Towle HC, Seelig S
The Journal of biological chemistry262(9)4284-9(1987 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following LOC299282 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LOC299282 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42334	NM_182474.1 Latest version!	Rattus norvegicus Serine protease inhibitor (LOC299282), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$356.30 $509.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LOC299282 ( NM_182474.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_872280.1 Rattus norvegicus Serine protease inhibitor (LOC299282), mRNA.

Price & Availability↑

CloneID	ORa42334
Clone ID Related Accession (Same CDS sequence)	NM_182474.1
Accession Version	NM_182474.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Rattus norvegicus(Norway rat)
Product	Serine protease inhibitor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY298742.1. ##Evidence-Data-START## Transcript exon combination :: AY298742.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCACACT GGGGAAGGGA CACTCTATCC CATGAAGACC ACGGCAAGGG GAGACAACTG 
CACAGTCTCA CATTGGCTTC CAGCAACACT GACTTCGCAT TGAGCCTCTA CAAGAAGCTG 
GCTTTGAGGA ATCCAGATAA AAATGTTGTC TTCTCCCCTC TTAGCATCTC AGCTGCCTTG 
ACCATTTTGT CTCTGGGAGC AAAAGACAGC ACCATGGAAG AGATTCTAGA AGGTCTCAAG 
TTCAATCTCA CAGAGATCAC TGAGGAAGAA ATCCACCAGG GCTTTGGGCA CCTCCTACAG 
AGGCTCAGCC AGCCAGAGGA CCAGGTAGAG ATCAATACAG GTAGTGCCCT GTTTATTGAC 
AAAGAGCAGC CGATACTGTC AGAATTCCAG GAGAAGACAA GGGCTCTGTA CCAGGCTGAG 
GCCTTCATAG CTGACTTCAA GCAGCCCAAT GAGGCCAAAA AGCTCATCAA TGACTATGTG 
AGCAATCAGA CCCAGGGGAA GATCGCAGAA CTGTTCTCAG ACCTGGAGGA GAGGACATCC 
ATGGTGCTGG TGAACTATCT CCTATTTAAA GGCAAGATGC AGCAGGTGGA ATCCAGCTTG 
CAACCAGAGA CCCTGAAGAA GTGGAAGGAC TCTTTGATCC CTAGGATTAT AAATGATCTC 
CGCATGCCCA AGTTCTCCAT CTCCACAGAC TACAGTCTAA AAGAGGTCCT TCCAGAGCTG 
GGCATTAAGA AAGTCTTCTC CCAGCAAGCT GATCTGAGTA GGATCACAGG GACCAAGGAT 
CTGTATGTCT CTCAAGTGGT CCACAAGGCT GTGCTGGATG TGGATGAGAC AGGCACAGAA 
GCAACTGCTG CTACAGGGGT CGCTACAGTC ATACGTAGAC AACCTCGAAC TCTGAATTTC 
AACCGGCCAT TCATGGTGGT TATCACTGAC ATGGATAGTC AGTCTATCCT CTTTGTTGCC 
AAAATCACTA ACCCCAAGAG GCCTGTGAAA GTGCCCATGA TGAAGCTTGA GGACCTGACC 
ACACCCTATG TCCAGGATGA GGAGCTGAAC TGCACTGTTG TGGAGCTGAA GTACACAGGA 
AATGCCAGCG CCCTGTTTAT CCTCCCTGAC CAGGGCAAGA TGCAGCAGGT GGAAGCCAGC 
TTGCAACCAG AGACCCTGAG GAGATGGAAG GACTCTCTCA GGCCCAGCAT GATAGATGAG 
CTCTACCCGC CCAAGTTCTC CATCTCTGCC GACTACAGCG TGGAGGAGTG TAGGGCGCCC 
TCCAATGGTG AACAACGAGT GCTGTACAGT AAAGGCTTGT TCCCAGAAGA ATCCTGTTGC 
CGCATGTCGT TCTTGCTGGC GAGACGTTGG GCGCGAGACG TTGGGTGCGA GACAGAGGAG 
GTCCTTCCAG AGCTGGGCAT CAAAGAAGTC TTCTCCACAC AGGCTGACCT GTCTGGGATC 
ACAGGGGACA AGGACCTGAC GGTCTCTCAG GAGGCTGGAG CAGGAGGGAT GCTGAATCCT 
CCACTGGCTG CCAGCATTCT GGCTGTTCCC TCTGAAGACG TTGAGAAGCT GCCTGTGAGG 
AAACTCCTGC CGCTGCCTAC TGCCATCCTT CAGTTTGTAG TGGTGCACAA GGCTGTGCTG 
GATGTGGCTG AGACAGGCAC AGAAGCAGCC GCTGCCACAG GAGTCAAACT TGTTCCAATG 
TCTGCAAAAC TGGACCCTCT GATTATAGTT TTCAACCGGC CTTTTCTGAT AATTATGTCT 
GACACAGAAA CTGAAATAGC TCCCTTTTGG CCAAGATATT TAACCCCAAA TGAGATTCGA 
ACTTCCCAAG GGTTGACGCT TCTCCCCAGG CATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872280.1
CDS	41..1876
Translation	MAHWGRDTLSHEDHGKGRQLHSLTLASSNTDFALSLYKKLALRNPDKNVVFSPLSISAALTILSLGAKDSTMEEILEGLKFNLTEITEEEIHQGFGHLLQRLSQPEDQVEINTGSALFIDKEQPILSEFQEKTRALYQAEAFIADFKQPNEAKKLINDYVSNQTQGKIAELFSDLEERTSMVLVNYLLFKGKMQQVESSLQPETLKKWKDSLIPRIINDLRMPKFSISTDYSLKEVLPELGIKKVFSQQADLSRITGTKDLYVSQVVHKAVLDVDETGTEATAATGVATVIRRQPRTLNFNRPFMVVITDMDSQSILFVAKITNPKRPVKVPMMKLEDLTTPYVQDEELNCTVVELKYTGNASALFILPDQGKMQQVEASLQPETLRRWKDSLRPSMIDELYPPKFSISADYSVEECRAPSNGEQRVLYSKGLFPEESCCRMSFLLARRWARDVGCETEEVLPELGIKEVFSTQADLSGITGDKDLTVSQEAGAGGMLNPPLAASILAVPSEDVEKLPVRKLLPLPTAILQFVVVHKAVLDVAETGTEAAAATGVKLVPMSAKLDPLIIVFNRPFLIIMSDTETEIAPFWPRYLTPNEIRTSQGLTLLPRH

Target ORF information:

RefSeq Version	NM_182474.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Serine protease inhibitor (LOC299282), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182474.1

ORF Insert Sequence:

ATGGCACACT GGGGAAGGGA CACTCTATCC CATGAAGACC ACGGCAAGGG GAGACAACTG 
CACAGTCTCA CATTGGCTTC CAGCAACACT GACTTCGCAT TGAGCCTCTA CAAGAAGCTG 
GCTTTGAGGA ATCCAGATAA AAATGTTGTC TTCTCCCCTC TTAGCATCTC AGCTGCCTTG 
ACCATTTTGT CTCTGGGAGC AAAAGACAGC ACCATGGAAG AGATTCTAGA AGGTCTCAAG 
TTCAATCTCA CAGAGATCAC TGAGGAAGAA ATCCACCAGG GCTTTGGGCA CCTCCTACAG 
AGGCTCAGCC AGCCAGAGGA CCAGGTAGAG ATCAATACAG GTAGTGCCCT GTTTATTGAC 
AAAGAGCAGC CGATACTGTC AGAATTCCAG GAGAAGACAA GGGCTCTGTA CCAGGCTGAG 
GCCTTCATAG CTGACTTCAA GCAGCCCAAT GAGGCCAAAA AGCTCATCAA TGACTATGTG 
AGCAATCAGA CCCAGGGGAA GATCGCAGAA CTGTTCTCAG ACCTGGAGGA GAGGACATCC 
ATGGTGCTGG TGAACTATCT CCTATTTAAA GGCAAGATGC AGCAGGTGGA ATCCAGCTTG 
CAACCAGAGA CCCTGAAGAA GTGGAAGGAC TCTTTGATCC CTAGGATTAT AAATGATCTC 
CGCATGCCCA AGTTCTCCAT CTCCACAGAC TACAGTCTAA AAGAGGTCCT TCCAGAGCTG 
GGCATTAAGA AAGTCTTCTC CCAGCAAGCT GATCTGAGTA GGATCACAGG GACCAAGGAT 
CTGTATGTCT CTCAAGTGGT CCACAAGGCT GTGCTGGATG TGGATGAGAC AGGCACAGAA 
GCAACTGCTG CTACAGGGGT CGCTACAGTC ATACGTAGAC AACCTCGAAC TCTGAATTTC 
AACCGGCCAT TCATGGTGGT TATCACTGAC ATGGATAGTC AGTCTATCCT CTTTGTTGCC 
AAAATCACTA ACCCCAAGAG GCCTGTGAAA GTGCCCATGA TGAAGCTTGA GGACCTGACC 
ACACCCTATG TCCAGGATGA GGAGCTGAAC TGCACTGTTG TGGAGCTGAA GTACACAGGA 
AATGCCAGCG CCCTGTTTAT CCTCCCTGAC CAGGGCAAGA TGCAGCAGGT GGAAGCCAGC 
TTGCAACCAG AGACCCTGAG GAGATGGAAG GACTCTCTCA GGCCCAGCAT GATAGATGAG 
CTCTACCCGC CCAAGTTCTC CATCTCTGCC GACTACAGCG TGGAGGAGTG TAGGGCGCCC 
TCCAATGGTG AACAACGAGT GCTGTACAGT AAAGGCTTGT TCCCAGAAGA ATCCTGTTGC 
CGCATGTCGT TCTTGCTGGC GAGACGTTGG GCGCGAGACG TTGGGTGCGA GACAGAGGAG 
GTCCTTCCAG AGCTGGGCAT CAAAGAAGTC TTCTCCACAC AGGCTGACCT GTCTGGGATC 
ACAGGGGACA AGGACCTGAC GGTCTCTCAG GAGGCTGGAG CAGGAGGGAT GCTGAATCCT 
CCACTGGCTG CCAGCATTCT GGCTGTTCCC TCTGAAGACG TTGAGAAGCT GCCTGTGAGG 
AAACTCCTGC CGCTGCCTAC TGCCATCCTT CAGTTTGTAG TGGTGCACAA GGCTGTGCTG 
GATGTGGCTG AGACAGGCAC AGAAGCAGCC GCTGCCACAG GAGTCAAACT TGTTCCAATG 
TCTGCAAAAC TGGACCCTCT GATTATAGTT TTCAACCGGC CTTTTCTGAT AATTATGTCT 
GACACAGAAA CTGAAATAGC TCCCTTTTGG CCAAGATATT TAACCCCAAA TGAGATTCGA 
ACTTCCCAAG GGTTGACGCT TCTCCCCAGG CATTGA