Cbx3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cbx3
Entrez Gene ID	297093
Full Name	chromobox 3
Synonyms	Hp1-gamma
General protein information	Preferred Names chromobox 3 Names chromobox protein homolog 3 HP1 gamma chromobox homolog 3 (HP1 gamma homolog, Drosophila) heterochromatin protein 1 gamma
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001008313.2	NP_001008314.2	chromobox protein homolog 3
XM_006236484.3	XP_006236546.1	chromobox protein homolog 3 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CBX3	XP_005628705.1
Danio rerio (zebrafish)	cbx3a	NP_001038867.1
Pan troglodytes (chimpanzee)	CBX3	XP_001161276.2
	CBX3	XP_001095397.2
Bos taurus (cattle)	CBX3	NP_001094668.1
Rattus norvegicus (Norway rat)	Cbx3	NP_001008314.2
Homo sapiens (human)	CBX3	NP_009207.2
Mus musculus (house mouse)	Cbx3	NP_031650.3
Xenopus tropicalis (tropical clawed frog)	cbx3	NP_001116264.1
Gallus gallus (chicken)	CBX3	NP_989974.1

Gene Ontology
Bibliography

Related articles in PubMed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.
Gilmore JM, Sardiu ME, Groppe BD, Thornton JL, Liu X, Dayebgadoh G, Banks CA, Slaughter BD, Unruh JR, Workman JL, Florens L, Washburn MP
PloS one11(6)e0155492(2016)

Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes.
Duong HA, Weitz CJ
Nature structural & molecular biology21(2)126-32(2014 Feb)

Analysis of the human HP1 interactome reveals novel binding partners.
Rosnoblet C, Vandamme J, V?lkel P, Angrand PO
Biochemical and biophysical research communications413(2)206-11(2011 Sep)

Glucocorticoids induce long-lasting effects in neural stem cells resulting in senescence-related alterations.
Bose R, Moors M, Tofighi R, Cascante A, Hermanson O, Ceccatelli S
Cell death & disease1e92(2010 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cbx3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cbx3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11341	NM_001008313.2 Latest version!	Rattus norvegicus chromobox 3 (Cbx3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa11341	XM_006236484.3 Latest version!	Rattus norvegicus chromobox 3 (Cbx3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cbx3 ( NM_001008313.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001008314.2 Rattus norvegicus chromobox 3 (Cbx3), mRNA.

Price & Availability↑

CloneID	ORa11341
Clone ID Related Accession (Same CDS sequence)	NM_001008313.2 , XM_006236484.3
Accession Version	NM_001008313.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Rattus norvegicus(Norway rat)
Product	chromobox protein homolog 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC086601.1. On Dec 26, 2004 this sequence version replaced NM_001008313.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC086601.1, BC127508.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCCA ATAAAACTAC ATTGCAAAAA ATGGGAAAGA AACAGAATGG AAAGAGTAAA 
AAAGTTGAAG AGGCAGAGCC TGAAGAATTT GTGGTAGAAA AAGTACTGGA CCGTCGTGTA 
GTGAATGGGA AGGTGGAGTA TTTCCTGAAG TGGAAGGGGT TCACAGATGC TGATAATACT 
TGGGAACCAG AAGAAAATTT AGATTGTCCA GAATTAATTG AAGCATTTCT TAATTCTCAA 
AAAGCTGGTA AAGAAAAAGA TGGTACAAAA AGGAAATCTT TATCTGACAG TGAATCTGAT 
GATAGCAAAT CGAAGAAGAA GAGAGATGCT GCTGACAAGC CCAGGGGCTT TGCCAGGGGC 
CTTGACCCTG AGCGAATAAT CGGTGCCACA GACAGCAGTG GAGAGCTAAT GTTTCTCATG 
AAATGGAAGG ACTCAGATGA AGCTGACTTG GTGCTGGCAA AGGAGGCGAA TATGAAGTGT 
CCTCAGATTG TCATCGCCTT CTATGAGGAG AGGCTGACTT GGCATTCTTG TCCCGAAGAT 
GAAGCACAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008314.2
CDS	70..621
Translation	MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPEDEAQ

Target ORF information:

RefSeq Version	NM_001008313.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus chromobox 3 (Cbx3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008313.2

ORF Insert Sequence:

ATGGCCTCCA ATAAAACTAC ATTGCAAAAA ATGGGAAAGA AACAGAATGG AAAGAGTAAA 
AAAGTTGAAG AGGCAGAGCC TGAAGAATTT GTGGTAGAAA AAGTACTGGA CCGTCGTGTA 
GTGAATGGGA AGGTGGAGTA TTTCCTGAAG TGGAAGGGGT TCACAGATGC TGATAATACT 
TGGGAACCAG AAGAAAATTT AGATTGTCCA GAATTAATTG AAGCATTTCT TAATTCTCAA 
AAAGCTGGTA AAGAAAAAGA TGGTACAAAA AGGAAATCTT TATCTGACAG TGAATCTGAT 
GATAGCAAAT CGAAGAAGAA GAGAGATGCT GCTGACAAGC CCAGGGGCTT TGCCAGGGGC 
CTTGACCCTG AGCGAATAAT CGGTGCCACA GACAGCAGTG GAGAGCTAAT GTTTCTCATG 
AAATGGAAGG ACTCAGATGA AGCTGACTTG GTGCTGGCAA AGGAGGCGAA TATGAAGTGT 
CCTCAGATTG TCATCGCCTT CTATGAGGAG AGGCTGACTT GGCATTCTTG TCCCGAAGAT 
GAAGCACAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cbx3 ( XM_006236484.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236546.1 Rattus norvegicus chromobox 3 (Cbx3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa11341
Clone ID Related Accession (Same CDS sequence)	NM_001008313.2 , XM_006236484.3
Accession Version	XM_006236484.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	chromobox protein homolog 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236484.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTCCA ATAAAACTAC ATTGCAAAAA ATGGGAAAGA AACAGAATGG AAAGAGTAAA 
AAAGTTGAAG AGGCAGAGCC TGAAGAATTT GTGGTAGAAA AAGTACTGGA CCGTCGTGTA 
GTGAATGGGA AGGTGGAGTA TTTCCTGAAG TGGAAGGGGT TCACAGATGC TGATAATACT 
TGGGAACCAG AAGAAAATTT AGATTGTCCA GAATTAATTG AAGCATTTCT TAATTCTCAA 
AAAGCTGGTA AAGAAAAAGA TGGTACAAAA AGGAAATCTT TATCTGACAG TGAATCTGAT 
GATAGCAAAT CGAAGAAGAA GAGAGATGCT GCTGACAAGC CCAGGGGCTT TGCCAGGGGC 
CTTGACCCTG AGCGAATAAT CGGTGCCACA GACAGCAGTG GAGAGCTAAT GTTTCTCATG 
AAATGGAAGG ACTCAGATGA AGCTGACTTG GTGCTGGCAA AGGAGGCGAA TATGAAGTGT 
CCTCAGATTG TCATCGCCTT CTATGAGGAG AGGCTGACTT GGCATTCTTG TCCCGAAGAT 
GAAGCACAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236546.1
CDS	764..1315
Translation	MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPEDEAQ

Target ORF information:

RefSeq Version	XM_006236484.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus chromobox 3 (Cbx3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236484.3

ORF Insert Sequence:

ATGGCCTCCA ATAAAACTAC ATTGCAAAAA ATGGGAAAGA AACAGAATGG AAAGAGTAAA 
AAAGTTGAAG AGGCAGAGCC TGAAGAATTT GTGGTAGAAA AAGTACTGGA CCGTCGTGTA 
GTGAATGGGA AGGTGGAGTA TTTCCTGAAG TGGAAGGGGT TCACAGATGC TGATAATACT 
TGGGAACCAG AAGAAAATTT AGATTGTCCA GAATTAATTG AAGCATTTCT TAATTCTCAA 
AAAGCTGGTA AAGAAAAAGA TGGTACAAAA AGGAAATCTT TATCTGACAG TGAATCTGAT 
GATAGCAAAT CGAAGAAGAA GAGAGATGCT GCTGACAAGC CCAGGGGCTT TGCCAGGGGC 
CTTGACCCTG AGCGAATAAT CGGTGCCACA GACAGCAGTG GAGAGCTAAT GTTTCTCATG 
AAATGGAAGG ACTCAGATGA AGCTGACTTG GTGCTGGCAA AGGAGGCGAA TATGAAGTGT 
CCTCAGATTG TCATCGCCTT CTATGAGGAG AGGCTGACTT GGCATTCTTG TCCCGAAGAT 
GAAGCACAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.
PloS one11(6)e0155492(2016)
Gilmore JM,Sardiu ME,Groppe BD,Thornton JL,Liu X,Dayebgadoh G,Banks CA,Slaughter BD,Unruh JR,Workman JL,Florens L,Washburn MP

Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes.
Nature structural & molecular biology21(2)126-32(2014 Feb)
Duong HA,Weitz CJ

Analysis of the human HP1 interactome reveals novel binding partners.
Biochemical and biophysical research communications413(2)206-11(2011 Sep)
Rosnoblet C,Vandamme J,V?lkel P,Angrand PO

Glucocorticoids induce long-lasting effects in neural stem cells resulting in senescence-related alterations.
Cell death & disease1e92(2010 Nov)
Bose R,Moors M,Tofighi R,Cascante A,Hermanson O,Ceccatelli S