Minpp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Minpp1
Entrez Gene ID	29688
Full Name	multiple inositol-polyphosphate phosphatase 1
General protein information	Preferred Names multiple inositol-polyphosphate phosphatase 1 Names multiple inositol polyphosphate phosphatase 1 2,3-BPG phosphatase 2,3-bisphosphoglycerate 3-phosphatase inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase ins(1,3,4,5)P(4) 3-phosphatase multiple inositol polyphosphate histidine phosphatase 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q52
Summary	catalyzes the hydrolysis of Ins(1,3,4,5,6)P5, first to Ins(1,4,5,6)P4 and then to Ins(1,4,5)P3, by consecutive 3- and 6-phosphatase activities [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008760327.2	XP_008758549.1	multiple inositol polyphosphate phosphatase 1 isoform X1
NM_019263.1	NP_062136.1	multiple inositol polyphosphate phosphatase 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	MINPP1	XP_507896.3
Canis lupus familiaris (dog)	MINPP1	XP_543588.2
Mus musculus (house mouse)	Minpp1	NP_034929.1
Gallus gallus (chicken)	MINPP1	NP_989975.1
Drosophila melanogaster (fruit fly)	Mipp2	NP_511055.1
Arabidopsis thaliana (thale cress)	AT1G09870	NP_563856.1
Oryza sativa (rice)	Os03g0818100	NP_001051705.1
Homo sapiens (human)	MINPP1	NP_004888.2
	MINPP1	XP_001101346.1
Xenopus tropicalis (tropical clawed frog)	minpp1	XP_002935472.2
Bos taurus (cattle)	MINPP1	NP_001033664.2
Danio rerio (zebrafish)	minpp1a	NP_001071025.1
Rattus norvegicus (Norway rat)	Minpp1	NP_062136.1
Rattus norvegicus (Norway rat)	RGD1564801	XP_574368.1
Danio rerio (zebrafish)	minpp1b	NP_957394.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003555	XP_313302.4

Gene Ontology
Bibliography

Related articles in PubMed

Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt.
Cho J, King JS, Qian X, Harwood AJ, Shears SB
Proceedings of the National Academy of Sciences of the United States of America105(16)5998-6003(2008 Apr)

Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas.
Gimm O, Chi H, Dahia PL, Perren A, Hinze R, Komminoth P, Dralle H, Reynolds PR, Eng C
The Journal of clinical endocrinology and metabolism86(4)1801-5(2001 Apr)

The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification.
Caffrey JJ, Hidaka K, Matsuda M, Hirata M, Shears SB
FEBS letters442(1)99-104(1999 Jan)

Molecular cloning and expression of a rat hepatic multiple inositol polyphosphate phosphatase.
Craxton A, Caffrey JJ, Burkhart W, Safrany ST, Shears SB
The Biochemical journal328 ( Pt 1)75-81(1997 Nov)

Hepatic Ins(1,3,4,5)P4 3-phosphatase is compartmentalized inside endoplasmic reticulum.
Ali N, Craxton A, Shears SB
The Journal of biological chemistry268(9)6161-7(1993 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Minpp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Minpp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04207	NM_019263.1 Latest version!	Rattus norvegicus multiple inositol-polyphosphate phosphatase 1 (Minpp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$286.30 $409.00
ORa43346	XM_008760327.2 Latest version!	Rattus norvegicus multiple inositol-polyphosphate phosphatase 1 (Minpp1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Minpp1 ( NM_019263.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062136.1 Rattus norvegicus multiple inositol-polyphosphate phosphatase 1 (Minpp1), mRNA.

Price & Availability↑

CloneID	ORa04207
Clone ID Related Accession (Same CDS sequence)	NM_019263.1
Accession Version	NM_019263.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1446bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	multiple inositol polyphosphate phosphatase 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF012714.2, CO388212.1 and CV120065.1. On or before Oct 28, 2007 this sequence version replaced XM_342044.3, XM_001079775.1. ##Evidence-Data-START## Transcript exon combination :: AF012714.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTCGCG GCGCGCGCAG CCACCTCTCG GCCTCGGTAG CCCTCGCCGC GGTCCTGGCT 
GCGGCGCTGC TCTCGTCGTT CGCGCGCTGC TCTCTCCCGG GGCGCGGCGA CCCGGTGGCT 
TCGGTGCTTA GCCCCTACTT CGGCACGAAG ACACGCTACG AAGATGTCAA CCCCTGGCTG 
CTGGGCGACC CGGTGGCGCC GCGACGGGAC CCGGAGCTGC TGGCGGGGAC TTGCACCCCG 
GTGCAGCTGG TCGCCCTCAT CCGTCACGGC ACCCGCTACC CTACGACCAA GCAGATCCGC 
AAGCTGAGGC AGCTGCAGGG GCTGCTGCAG ACCCGCGAGT CCGTGGATGG CGGGAGCCGA 
GTGGCCGCCG CTCTGGACCA ATGGCCGCTG TGGTACGATG ACTGGATGGA CGGGCAGCTG 
GTGGAAAAGG GGCGGCAGGA CATGCGACAG CTGGCCCTGC GTCTGGCCGC CCTCTTCCCT 
GACCTCTTCT GCCGGGAGAA CTACGGCCGC CTGCGGCTGA TCACCAGCTC CAAGCACCGC 
TGTGTGGACA GCAGCGCCGC CTTCCTCCAA GGGTTGTGGC AACATTACCA CCCAGGATTG 
CCACCTCCCG ACGTCTCAGA CATGGAGTGT GACCCTCCGA GAGTTAATGA TAAGCTAATG 
AGGTTCTTCG ATCACTGTGA GAAGTTTTTA ACCGAAGTCG AAAGAAACGC CACGGCTCTT 
TATCATGTGG AAGCCTTCAA AACCGGGCCA GAAATGCAGA CAGTTTTAAA GAAAGTTGCA 
GCCACTTTGC AAGTGCCAGT GAACAATTTA AATGCAGACT TAATTCAGGT AGCCTTTTTC 
ACCTGTTCGT TTGACCTGGC AATTCAAGGT GTCCATTCTC CCTGGTGCGA TGTGTTTGAC 
GTAGATGATG CGAAGGTTCT GGAATACTTA AATGATCTGA AACAGTACTG GAAACGAAGT 
TATGGCTATG CCATTAACAG CCGGTCCAGC TGCAACCTGT TTCAGGACAT TTTTCTACAC 
CTGGACAAAG CAGTTGAGCA GAAGCAAAGG TCTCAGCCGG TCTCTTCTCC AGTCATCCTC 
CAGTTTGGTC ATGCGGAGAC CCTCCTACCC CTGCTCTCGC TCATGGGCTA CTTCAAGGAC 
AAGGAGCCCC TGACAGCATA CAATTTTGAG GAGCAGGTGC ATCGCGAGTT CCGAAGTGGT 
CACATCGTAC CATATGCTTC AAACCTAATA TTTGTGCTTT ACCATTGTGA AGACGCACAG 
ACCCCTCAAG AAAAATTCCA GATACAAATG CTGCTGAATG AAAAGGTGTT ACCCTTAGCT 
CACTCGCAGA AAACTGTTGC CTTGTATGAG GATCTGAAGA ACCACTACCA GGACATTCTT 
CAGAGCTGTC AAACTAGTAA AGAATGTAAC CTACCCAAGG TGAACATCAC GTCCGACGAG 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062136.1
CDS	1..1446
Translation	MLRGARSHLSASVALAAVLAAALLSSFARCSLPGRGDPVASVLSPYFGTKTRYEDVNPWLLGDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRKLRQLQGLLQTRESVDGGSRVAAALDQWPLWYDDWMDGQLVEKGRQDMRQLALRLAALFPDLFCRENYGRLRLITSSKHRCVDSSAAFLQGLWQHYHPGLPPPDVSDMECDPPRVNDKLMRFFDHCEKFLTEVERNATALYHVEAFKTGPEMQTVLKKVAATLQVPVNNLNADLIQVAFFTCSFDLAIQGVHSPWCDVFDVDDAKVLEYLNDLKQYWKRSYGYAINSRSSCNLFQDIFLHLDKAVEQKQRSQPVSSPVILQFGHAETLLPLLSLMGYFKDKEPLTAYNFEEQVHREFRSGHIVPYASNLIFVLYHCEDAQTPQEKFQIQMLLNEKVLPLAHSQKTVALYEDLKNHYQDILQSCQTSKECNLPKVNITSDEL

Target ORF information:

RefSeq Version	NM_019263.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus multiple inositol-polyphosphate phosphatase 1 (Minpp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019263.1

ORF Insert Sequence:

ATGCTTCGCG GCGCGCGCAG CCACCTCTCG GCCTCGGTAG CCCTCGCCGC GGTCCTGGCT 
GCGGCGCTGC TCTCGTCGTT CGCGCGCTGC TCTCTCCCGG GGCGCGGCGA CCCGGTGGCT 
TCGGTGCTTA GCCCCTACTT CGGCACGAAG ACACGCTACG AAGATGTCAA CCCCTGGCTG 
CTGGGCGACC CGGTGGCGCC GCGACGGGAC CCGGAGCTGC TGGCGGGGAC TTGCACCCCG 
GTGCAGCTGG TCGCCCTCAT CCGTCACGGC ACCCGCTACC CTACGACCAA GCAGATCCGC 
AAGCTGAGGC AGCTGCAGGG GCTGCTGCAG ACCCGCGAGT CCGTGGATGG CGGGAGCCGA 
GTGGCCGCCG CTCTGGACCA ATGGCCGCTG TGGTACGATG ACTGGATGGA CGGGCAGCTG 
GTGGAAAAGG GGCGGCAGGA CATGCGACAG CTGGCCCTGC GTCTGGCCGC CCTCTTCCCT 
GACCTCTTCT GCCGGGAGAA CTACGGCCGC CTGCGGCTGA TCACCAGCTC CAAGCACCGC 
TGTGTGGACA GCAGCGCCGC CTTCCTCCAA GGGTTGTGGC AACATTACCA CCCAGGATTG 
CCACCTCCCG ACGTCTCAGA CATGGAGTGT GACCCTCCGA GAGTTAATGA TAAGCTAATG 
AGGTTCTTCG ATCACTGTGA GAAGTTTTTA ACCGAAGTCG AAAGAAACGC CACGGCTCTT 
TATCATGTGG AAGCCTTCAA AACCGGGCCA GAAATGCAGA CAGTTTTAAA GAAAGTTGCA 
GCCACTTTGC AAGTGCCAGT GAACAATTTA AATGCAGACT TAATTCAGGT AGCCTTTTTC 
ACCTGTTCGT TTGACCTGGC AATTCAAGGT GTCCATTCTC CCTGGTGCGA TGTGTTTGAC 
GTAGATGATG CGAAGGTTCT GGAATACTTA AATGATCTGA AACAGTACTG GAAACGAAGT 
TATGGCTATG CCATTAACAG CCGGTCCAGC TGCAACCTGT TTCAGGACAT TTTTCTACAC 
CTGGACAAAG CAGTTGAGCA GAAGCAAAGG TCTCAGCCGG TCTCTTCTCC AGTCATCCTC 
CAGTTTGGTC ATGCGGAGAC CCTCCTACCC CTGCTCTCGC TCATGGGCTA CTTCAAGGAC 
AAGGAGCCCC TGACAGCATA CAATTTTGAG GAGCAGGTGC ATCGCGAGTT CCGAAGTGGT 
CACATCGTAC CATATGCTTC AAACCTAATA TTTGTGCTTT ACCATTGTGA AGACGCACAG 
ACCCCTCAAG AAAAATTCCA GATACAAATG CTGCTGAATG AAAAGGTGTT ACCCTTAGCT 
CACTCGCAGA AAACTGTTGC CTTGTATGAG GATCTGAAGA ACCACTACCA GGACATTCTT 
CAGAGCTGTC AAACTAGTAA AGAATGTAAC CTACCCAAGG TGAACATCAC GTCCGACGAG 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Minpp1 ( XM_008760327.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758549.1 Rattus norvegicus multiple inositol-polyphosphate phosphatase 1 (Minpp1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43346
Clone ID Related Accession (Same CDS sequence)	XM_008760327.2
Accession Version	XM_008760327.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 921bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	multiple inositol polyphosphate phosphatase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760327.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTCGCG GCGCGCGCAG CCACCTCTCG GCCTCGGTAG CCCTCGCCGC GGTCCTGGCT 
GCGGCGCTGC TCTCGTCGTT CGCGCGCTGC TCTCTCCCGG GGCGCGGCGA CCCGGTGGCT 
TCGGTGCTTA GCCCCTACTT CGGCACGAAG ACACGCTACG AAGATGTCAA CCCCTGGCTG 
CTGGGCGACC CGGTGGCGCC GCGACGGGAC CCGGAGCTGC TGGCGGGGAC TTGCACCCCG 
GTGCAGCTGG TCGCCCTCAT CCGTCACGGC ACCCGCTACC CTACGACCAA GCAGATCCGC 
AAGCTGAGGC AGCTGCAGGG GCTGCTGCAG ACCCGCGAGT CCGTGGATGG CGGGAGCCGA 
GTGGCCGCCG CTCTGGACCA ATGGCCGCTG TGGTACGATG ACTGGATGGA CGGGCAGCTG 
GTGGAAAAGG GGCGGCAGGA CATGCGACAG CTGGCCCTGC GTCTGGCCGC CCTCTTCCCT 
GACCTCTTCT GCCGGGAGAA CTACGGCCGC CTGCGGCTGA TCACCAGCTC CAAGCACCGC 
TGTGTGGACA GCAGCGCCGC CTTCCTCCAA GGGTTGTGGC AACATTACCA CCCAGGATTG 
CCACCTCCCG ACGTCTCAGA CATGGAGTGT GACCCTCCGA GAGTTAATGA TAAGCTAATG 
AGGTTCTTCG ATCACTGTGA GAAGTTTTTA ACCGAAGTCG AAAGAAACGC CACGGCTCTT 
TATCATGTGG AAGCCTTCAA AACCGGGCCA GAAATGCAGA CAGTTTTAAA GAAAGTTGCA 
GCCACTTTGC AAGTGCCAGT GAACAATTTA AATGCAGGTC TCAGCCGGTC TCTTCTCCAG 
TCATCCTCCA GTTTGGTCAT GCGGAGACCC TCCTACCCCT GCTCTCGCTC ATGGGCTACT 
TCAAGGACAA GGAGCCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758549.1
CDS	89..1009
Translation	MLRGARSHLSASVALAAVLAAALLSSFARCSLPGRGDPVASVLSPYFGTKTRYEDVNPWLLGDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRKLRQLQGLLQTRESVDGGSRVAAALDQWPLWYDDWMDGQLVEKGRQDMRQLALRLAALFPDLFCRENYGRLRLITSSKHRCVDSSAAFLQGLWQHYHPGLPPPDVSDMECDPPRVNDKLMRFFDHCEKFLTEVERNATALYHVEAFKTGPEMQTVLKKVAATLQVPVNNLNAGLSRSLLQSSSSLVMRRPSYPCSRSWATSRTRSP

Target ORF information:

RefSeq Version	XM_008760327.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus multiple inositol-polyphosphate phosphatase 1 (Minpp1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760327.2

ORF Insert Sequence:

ATGCTTCGCG GCGCGCGCAG CCACCTCTCG GCCTCGGTAG CCCTCGCCGC GGTCCTGGCT 
GCGGCGCTGC TCTCGTCGTT CGCGCGCTGC TCTCTCCCGG GGCGCGGCGA CCCGGTGGCT 
TCGGTGCTTA GCCCCTACTT CGGCACGAAG ACACGCTACG AAGATGTCAA CCCCTGGCTG 
CTGGGCGACC CGGTGGCGCC GCGACGGGAC CCGGAGCTGC TGGCGGGGAC TTGCACCCCG 
GTGCAGCTGG TCGCCCTCAT CCGTCACGGC ACCCGCTACC CTACGACCAA GCAGATCCGC 
AAGCTGAGGC AGCTGCAGGG GCTGCTGCAG ACCCGCGAGT CCGTGGATGG CGGGAGCCGA 
GTGGCCGCCG CTCTGGACCA ATGGCCGCTG TGGTACGATG ACTGGATGGA CGGGCAGCTG 
GTGGAAAAGG GGCGGCAGGA CATGCGACAG CTGGCCCTGC GTCTGGCCGC CCTCTTCCCT 
GACCTCTTCT GCCGGGAGAA CTACGGCCGC CTGCGGCTGA TCACCAGCTC CAAGCACCGC 
TGTGTGGACA GCAGCGCCGC CTTCCTCCAA GGGTTGTGGC AACATTACCA CCCAGGATTG 
CCACCTCCCG ACGTCTCAGA CATGGAGTGT GACCCTCCGA GAGTTAATGA TAAGCTAATG 
AGGTTCTTCG ATCACTGTGA GAAGTTTTTA ACCGAAGTCG AAAGAAACGC CACGGCTCTT 
TATCATGTGG AAGCCTTCAA AACCGGGCCA GAAATGCAGA CAGTTTTAAA GAAAGTTGCA 
GCCACTTTGC AAGTGCCAGT GAACAATTTA AATGCAGGTC TCAGCCGGTC TCTTCTCCAG 
TCATCCTCCA GTTTGGTCAT GCGGAGACCC TCCTACCCCT GCTCTCGCTC ATGGGCTACT 
TCAAGGACAA GGAGCCCCTG A