Vtcn1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Vtcn1
Entrez Gene ID	295322
Full Name	V-set domain containing T cell activation inhibitor 1
Synonyms	RGD1311204
General protein information	Preferred Names V-set domain containing T cell activation inhibitor 1 Names V-set domain-containing T-cell activation inhibitor 1 immune costimulatory protein B7-H4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34

mRNA and Protein(s)

mRNA	Protein	Name
NM_001024244.1	NP_001019415.1	V-set domain-containing T-cell activation inhibitor 1 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Vtcn1	NP_001019415.1
Bos taurus (cattle)	VTCN1	XP_002686167.2
Homo sapiens (human)	VTCN1	NP_078902.2
Canis lupus familiaris (dog)	VTCN1	XP_005630720.1
Gallus gallus (chicken)	VTCN1	XP_416546.4
	LOC714123	XP_001103715.1
Mus musculus (house mouse)	Vtcn1	NP_848709.2
Xenopus tropicalis (tropical clawed frog)	vtcn1	NP_001008189.1
Pan troglodytes (chimpanzee)	VTCN1	XP_003308340.1
Danio rerio (zebrafish)	si:dkey-174k18.6	XP_003199259.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of the novel co-stimulatory molecule B7-H4 by renal tubular epithelial cells.
Chen Y, Yang C, Xie Z, Zou L, Ruan Z, Zhang X, Tang Y, Fei L, Jia Z, Wu Y
Kidney international70(12)2092-9(2006 Dec)

Generation and characterization of B7-H4/B7S1/B7x-deficient mice.
Suh WK, Wang S, Duncan GS, Miyazaki Y, Cates E, Walker T, Gajewska BU, Deenick E, Dawicki W, Okada H, Wakeham A, Itie A, Watts TH, Ohashi PS, Jordana M, Yoshida H, Mak TW
Molecular and cellular biology26(17)6403-11(2006 Sep)

BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation.
Nguyen T, Liu XK, Zhang Y, Dong C
Journal of immunology (Baltimore, Md. : 1950)176(12)7354-60(2006 Jun)

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma.
Kryczek I, Zou L, Rodriguez P, Zhu G, Wei S, Mottram P, Brumlik M, Cheng P, Curiel T, Myers L, Lackner A, Alvarez X, Ochoa A, Chen L, Zou W
The Journal of experimental medicine203(4)871-81(2006 Apr)

The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation.
Salceda S, Tang T, Kmet M, Munteanu A, Ghosh M, Macina R, Liu W, Pilkington G, Papkoff J
Experimental cell research306(1)128-41(2005 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Vtcn1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vtcn1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06079	NM_001024244.1 Latest version!	Rattus norvegicus V-set domain containing T cell activation inhibitor 1 (Vtcn1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Vtcn1 ( NM_001024244.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001019415.1 Rattus norvegicus V-set domain containing T cell activation inhibitor 1 (Vtcn1), mRNA.

Price & Availability↑

CloneID	ORa06079
Clone ID Related Accession (Same CDS sequence)	NM_001024244.1
Accession Version	NM_001024244.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Rattus norvegicus(Norway rat)
Product	V-set domain-containing T-cell activation inhibitor 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095842.1. On May 27, 2005 this sequence version replaced XM_227553.3. ##Evidence-Data-START## Transcript exon combination :: BC095842.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689601 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCCT TGGGGCAGAT CATCTTTTGG AGTATTATTA ACGTCATCAT CATCCTGGCT 
GGAGCCATCG TACTCATCAT TGGCTTTGGT ATTTCAGGCA AGCACTTCAT CACGGTCACA 
ACCTTCACCT CAGCTGGAAA TATTGGAGAG GACGGGACCC TGAGCTGCAC GTTTGAACCT 
GACATCAAAC TCAACGGCAT CGTCATCCAG TGGCTGAAGG AAGGCATCAA AGGTTTGGTC 
CATGAGTTCA AAGAGGGCAA AGACGACCTC TCACAGCAGC ACGAGATGTT TCGAGGCCGG 
ACAGCAGTGT TTGCAGATCA AGTGGTGGTT GGCAATGCTT CCCTGAGACT GAAAAATGTG 
CAGCTCACTG ATGCTGGCAC CTACACATGT TATATCCACA CCTCAAAAGG CAAAGGGAAT 
GCTAACCTTG AGTATAAGAC TGGAGCCTTC AGTATGCCAG AGATTAATGT GGACTATAAT 
GCCAGTTCGG AGAGTCTACG CTGTGAGGCT CCTCGGTGGT TCCCCCAGCC CACAGTGGCC 
TGGGCATCTC AAGTTGACCA AGGAGCCAAC TTCTCAGAAG TCTCCAACAC TAGCTTCGAG 
TTGAACTCTG AGAATGTGAC CATGAAGGTC GTATCTGTGC TCTACAATGT CACAATCAAC 
AACACATACT CCTGTATGAT CGAAAACGAT ATTGCCAAAG CCACAGGGGA CATCAAAGTG 
ACAGATTCAG AGGTCAAAAG GCGTAGTCAG CTGGAGCTGC TGAACTCTGG GCCTTCTCCG 
TGTGTTTCTT CTGTCTCTGC CGCTGGCTGG GCACTCCTAT CTCTCTCCTG TTGCCTGATG 
CTAAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019415.1
CDS	95..943
Translation	MASLGQIIFWSIINVIIILAGAIVLIIGFGISGKHFITVTTFTSAGNIGEDGTLSCTFEPDIKLNGIVIQWLKEGIKGLVHEFKEGKDDLSQQHEMFRGRTAVFADQVVVGNASLRLKNVQLTDAGTYTCYIHTSKGKGNANLEYKTGAFSMPEINVDYNASSESLRCEAPRWFPQPTVAWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATGDIKVTDSEVKRRSQLELLNSGPSPCVSSVSAAGWALLSLSCCLMLR

Target ORF information:

RefSeq Version	NM_001024244.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus V-set domain containing T cell activation inhibitor 1 (Vtcn1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024244.1

ORF Insert Sequence:

ATGGCTTCCT TGGGGCAGAT CATCTTTTGG AGTATTATTA ACGTCATCAT CATCCTGGCT 
GGAGCCATCG TACTCATCAT TGGCTTTGGT ATTTCAGGCA AGCACTTCAT CACGGTCACA 
ACCTTCACCT CAGCTGGAAA TATTGGAGAG GACGGGACCC TGAGCTGCAC GTTTGAACCT 
GACATCAAAC TCAACGGCAT CGTCATCCAG TGGCTGAAGG AAGGCATCAA AGGTTTGGTC 
CATGAGTTCA AAGAGGGCAA AGACGACCTC TCACAGCAGC ACGAGATGTT TCGAGGCCGG 
ACAGCAGTGT TTGCAGATCA AGTGGTGGTT GGCAATGCTT CCCTGAGACT GAAAAATGTG 
CAGCTCACTG ATGCTGGCAC CTACACATGT TATATCCACA CCTCAAAAGG CAAAGGGAAT 
GCTAACCTTG AGTATAAGAC TGGAGCCTTC AGTATGCCAG AGATTAATGT GGACTATAAT 
GCCAGTTCGG AGAGTCTACG CTGTGAGGCT CCTCGGTGGT TCCCCCAGCC CACAGTGGCC 
TGGGCATCTC AAGTTGACCA AGGAGCCAAC TTCTCAGAAG TCTCCAACAC TAGCTTCGAG 
TTGAACTCTG AGAATGTGAC CATGAAGGTC GTATCTGTGC TCTACAATGT CACAATCAAC 
AACACATACT CCTGTATGAT CGAAAACGAT ATTGCCAAAG CCACAGGGGA CATCAAAGTG 
ACAGATTCAG AGGTCAAAAG GCGTAGTCAG CTGGAGCTGC TGAACTCTGG GCCTTCTCCG 
TGTGTTTCTT CTGTCTCTGC CGCTGGCTGG GCACTCCTAT CTCTCTCCTG TTGCCTGATG 
CTAAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of the novel co-stimulatory molecule B7-H4 by renal tubular epithelial cells.
Kidney international70(12)2092-9(2006 Dec)
Chen Y,Yang C,Xie Z,Zou L,Ruan Z,Zhang X,Tang Y,Fei L,Jia Z,Wu Y

Generation and characterization of B7-H4/B7S1/B7x-deficient mice.
Molecular and cellular biology26(17)6403-11(2006 Sep)
Suh WK,Wang S,Duncan GS,Miyazaki Y,Cates E,Walker T,Gajewska BU,Deenick E,Dawicki W,Okada H,Wakeham A,Itie A,Watts TH,Ohashi PS,Jordana M,Yoshida H,Mak TW

BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation.
Journal of immunology (Baltimore, Md. : 1950)176(12)7354-60(2006 Jun)
Nguyen T,Liu XK,Zhang Y,Dong C

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma.
The Journal of experimental medicine203(4)871-81(2006 Apr)
Kryczek I,Zou L,Rodriguez P,Zhu G,Wei S,Mottram P,Brumlik M,Cheng P,Curiel T,Myers L,Lackner A,Alvarez X,Ochoa A,Chen L,Zou W

The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation.
Experimental cell research306(1)128-41(2005 May)
Salceda S,Tang T,Kmet M,Munteanu A,Ghosh M,Macina R,Liu W,Pilkington G,Papkoff J

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Vtcn1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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