Ptgs2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ptgs2
Entrez Gene ID	29527
Full Name	prostaglandin-endoperoxide synthase 2
Synonyms	COX-2,Cox2
General protein information	Preferred Names prostaglandin-endoperoxide synthase 2 Names prostaglandin G/H synthase 2 PGH synthase 2 PGHS-2 PHS II cyclooxygenase-2 prostaglandin H2 synthase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q21
Summary	catalyzes the conversion of arachidonic acid products to prostaglandin; may play a role in response to endotoxic shock; may a role in long term potentiation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017232.3	NP_058928.3	prostaglandin G/H synthase 2 precursor

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	PTGS2	NP_001161191.1
Danio rerio (zebrafish)	ptgs2b	NP_001020675.1
Mus musculus (house mouse)	Ptgs2	NP_035328.2
Canis lupus familiaris (dog)	PTGS2	NP_001003354.1
Pan troglodytes (chimpanzee)	PTGS2	XP_524999.3
	PTGS2	XP_001107538.2
Rattus norvegicus (Norway rat)	Ptgs2	NP_058928.3
Homo sapiens (human)	PTGS2	NP_000954.1
Bos taurus (cattle)	PTGS2	NP_776870.1
Xenopus tropicalis (tropical clawed frog)	ptgs2	NP_001025697.1

Gene Ontology

The following Ptgs2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ptgs2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13107	NM_017232.3 Latest version!	Rattus norvegicus prostaglandin-endoperoxide synthase 2 (Ptgs2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ptgs2 ( NM_017232.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058928.3 Rattus norvegicus prostaglandin-endoperoxide synthase 2 (Ptgs2), mRNA.

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CloneID	ORa13107
Clone ID Related Accession (Same CDS sequence)	NM_017232.3
Accession Version	NM_017232.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1815bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	prostaglandin G/H synthase 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U04300.1. On Jun 10, 2007 this sequence version replaced NM_017232.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L20085.1, U04300.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCTCTTCC GAGCTGTGCT GCTCTGCGCT GCCCTGGCGC TCAGCCATGC AGCAAATCCT 
TGCTGTTCCA ACCCATGTCA AAACCGTGGT GAATGTATGA GCATAGGATT TGACCAATAT 
AAATGTGACT GTACCCGGAC TGGATTCTAC GGTGAAAACT GTACTACGCC TGAGTTTCTG 
ACAAGAATCA AATTACTGCT GAAGCCCACC CCAAACACAG TACACTACAT CCTGACCCAC 
TTCAAGGGAG TCTGGAACAT TGTGAACAAC ATTCCCTTCC TTCGGAATTC AATCATGAGA 
TACGTGTTGA CGTCCAGATC ACATTTGATT GACAGCCCAC CAACTTACAA TGTGCACTAC 
GGTTACAAAA GTTGGGAAGC TTTCTCCAAC CTCTCCTACT ACACCAGGGC CCTTCCTCCT 
GTGGCTGATG ACTGCCCAAC TCCCATGGGT GTGAAAGGAA ATAAGGAACT TCCTGATTCA 
AAAGAAGTTC TGGAAAAGGT TCTTCTGAGG AGAGAGTTCA TCCCGGATCC CCAAGGCACA 
AATATGATGT TCGCATTCTT TGCCCAGCAC TTCACTCATC AGTTTTTCAA GACAGATCAG 
AAGCGAGGAC CTGGGTTCAC CCGAGGACTG GGCCATGGAG TGGACTTAAA TCATGTTTAC 
GGTGAAACTC TAGACAGACA ACATAAACTT CGACTTTTCC AGGATGGAAA ATTGAAATAT 
CAGGTCATCG GTGGAGAGGT GTATCCTCCC ACAGTCAAAG ACACTCAGGT AGACATGATC 
TACCCTCCCC ACGTCCCTGA GCACCTGCGG TTCGCTGTGG GGCAGGAAGT CTTTGGTCTG 
GTGCCGGGTC TGATGATGTA TGCTACCATC TGGCTTCGGG AGCACAACAG AGTGTGTGAT 
ATACTCAAAC AGGAGCATCC TGAGTGGGAT GACGAGCGAC TGTTCCAAAC CAGCAGGCTC 
ATACTGATAG GAGAGACGAT CAAGATAGTG ATCGAAGACT ACGTGCAACA CCTGAGCGGT 
TACCACTTCA AACTCAAGTT CGACCCAGAG CTGCTTTTCA ACCAGCAGTT CCAGTATCAG 
AACCGCATTG CCTCTGAATT CAACACACTC TATCACTGGC ATCCGCTGCT GCCGGACACC 
TTCAACATTG AAGACCAGGA GTACACTTTC AAACAGTTTC TCTACAACAA CTCCATCCTC 
CTTGAACACG GACTTGCTCA CTTTGTTGAG TCATTCACCA GACAGATTGC TGGCCGGGTT 
GCTGGGGGAA GGAATGTTCC AATCGCTGTA CAAGCAGTGG CAAAGGCCTC CATTGACCAG 
AGCAGAGAGA TGAAATACCA GTCTCTCAAT GAGTACCGCA AACGCTTCTC CCTGAAACCT 
TACACATCGT TTGAAGAACT TACAGGAGAG AAAGAAATGG CTGCAGAGTT GAAAGCCCTC 
TACCATGACA TCGATGCCAT GGAACTGTAT CCCGCCCTGC TGGTGGAAAA GCCTCGTCCA 
GATGCTATCT TTGGGGAGAC CATGGTAGAA CTTGGAGCTC CATTCTCCTT GAAAGGCCTT 
ATGGGTAATC CCATCTGTTC TCCTCAATAC TGGAAACCTA GCACCTTCGG AGGAGAAGTG 
GGTTTTAGGA TCATCAACAC TGCCTCAATT CAGTCTCTCA TCTGCAATAA TGTGAAAGGG 
TGTCCCTTTG CCTCTTTCAA TGTGCAAGAC CCGCAGCCTA CCAAGACAGC CACCATCAAC 
GCAAGTGCCT CCCACTCCAG ACTAGATGAC ATTAACCCTA CAGTACTAAT CAAAAGGCGT 
TCAACTGAGC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058928.3
CDS	1..1815
Translation	MLFRAVLLCAALALSHAANPCCSNPCQNRGECMSIGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRNSIMRYVLTSRSHLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGTNMMFAFFAQHFTHQFFKTDQKRGPGFTRGLGHGVDLNHVYGETLDRQHKLRLFQDGKLKYQVIGGEVYPPTVKDTQVDMIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYTFKQFLYNNSILLEHGLAHFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYHDIDAMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFRIINTASIQSLICNNVKGCPFASFNVQDPQPTKTATINASASHSRLDDINPTVLIKRRSTEL

Target ORF information:

RefSeq Version	NM_017232.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus prostaglandin-endoperoxide synthase 2 (Ptgs2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017232.3

ORF Insert Sequence:

ATGCTCTTCC GAGCTGTGCT GCTCTGCGCT GCCCTGGCGC TCAGCCATGC AGCAAATCCT 
TGCTGTTCCA ACCCATGTCA AAACCGTGGT GAATGTATGA GCATAGGATT TGACCAATAT 
AAATGTGACT GTACCCGGAC TGGATTCTAC GGTGAAAACT GTACTACGCC TGAGTTTCTG 
ACAAGAATCA AATTACTGCT GAAGCCCACC CCAAACACAG TACACTACAT CCTGACCCAC 
TTCAAGGGAG TCTGGAACAT TGTGAACAAC ATTCCCTTCC TTCGGAATTC AATCATGAGA 
TACGTGTTGA CGTCCAGATC ACATTTGATT GACAGCCCAC CAACTTACAA TGTGCACTAC 
GGTTACAAAA GTTGGGAAGC TTTCTCCAAC CTCTCCTACT ACACCAGGGC CCTTCCTCCT 
GTGGCTGATG ACTGCCCAAC TCCCATGGGT GTGAAAGGAA ATAAGGAACT TCCTGATTCA 
AAAGAAGTTC TGGAAAAGGT TCTTCTGAGG AGAGAGTTCA TCCCGGATCC CCAAGGCACA 
AATATGATGT TCGCATTCTT TGCCCAGCAC TTCACTCATC AGTTTTTCAA GACAGATCAG 
AAGCGAGGAC CTGGGTTCAC CCGAGGACTG GGCCATGGAG TGGACTTAAA TCATGTTTAC 
GGTGAAACTC TAGACAGACA ACATAAACTT CGACTTTTCC AGGATGGAAA ATTGAAATAT 
CAGGTCATCG GTGGAGAGGT GTATCCTCCC ACAGTCAAAG ACACTCAGGT AGACATGATC 
TACCCTCCCC ACGTCCCTGA GCACCTGCGG TTCGCTGTGG GGCAGGAAGT CTTTGGTCTG 
GTGCCGGGTC TGATGATGTA TGCTACCATC TGGCTTCGGG AGCACAACAG AGTGTGTGAT 
ATACTCAAAC AGGAGCATCC TGAGTGGGAT GACGAGCGAC TGTTCCAAAC CAGCAGGCTC 
ATACTGATAG GAGAGACGAT CAAGATAGTG ATCGAAGACT ACGTGCAACA CCTGAGCGGT 
TACCACTTCA AACTCAAGTT CGACCCAGAG CTGCTTTTCA ACCAGCAGTT CCAGTATCAG 
AACCGCATTG CCTCTGAATT CAACACACTC TATCACTGGC ATCCGCTGCT GCCGGACACC 
TTCAACATTG AAGACCAGGA GTACACTTTC AAACAGTTTC TCTACAACAA CTCCATCCTC 
CTTGAACACG GACTTGCTCA CTTTGTTGAG TCATTCACCA GACAGATTGC TGGCCGGGTT 
GCTGGGGGAA GGAATGTTCC AATCGCTGTA CAAGCAGTGG CAAAGGCCTC CATTGACCAG 
AGCAGAGAGA TGAAATACCA GTCTCTCAAT GAGTACCGCA AACGCTTCTC CCTGAAACCT 
TACACATCGT TTGAAGAACT TACAGGAGAG AAAGAAATGG CTGCAGAGTT GAAAGCCCTC 
TACCATGACA TCGATGCCAT GGAACTGTAT CCCGCCCTGC TGGTGGAAAA GCCTCGTCCA 
GATGCTATCT TTGGGGAGAC CATGGTAGAA CTTGGAGCTC CATTCTCCTT GAAAGGCCTT 
ATGGGTAATC CCATCTGTTC TCCTCAATAC TGGAAACCTA GCACCTTCGG AGGAGAAGTG 
GGTTTTAGGA TCATCAACAC TGCCTCAATT CAGTCTCTCA TCTGCAATAA TGTGAAAGGG 
TGTCCCTTTG CCTCTTTCAA TGTGCAAGAC CCGCAGCCTA CCAAGACAGC CACCATCAAC 
GCAAGTGCCT CCCACTCCAG ACTAGATGAC ATTAACCCTA CAGTACTAAT CAAAAGGCGT 
TCAACTGAGC TGTAA