Cxcr5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cxcr5
Entrez Gene ID	29363
Full Name	C-X-C motif chemokine receptor 5
Synonyms	Blr1,NLR
General protein information	Preferred Names C-X-C motif chemokine receptor 5 Names C-X-C chemokine receptor type 5 CXC-R5 CXCR-5 burkitt lymphoma receptor 1 homolog chemochine (C-X-C motif) receptor 5 chemokine (C-X-C motif) receptor 5 neurolymphatic receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q22
Summary	G-protein coupled receptor that may play a role in the nervous and immune systems [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006242901.3	XP_006242963.1	C-X-C chemokine receptor type 5 isoform X1
NM_053303.1	NP_445755.1	C-X-C chemokine receptor type 5

Pathways from BioSystems

Homologies

	CXCR5	XP_001100017.1
Bos taurus (cattle)	CXCR5	NP_001011675.1
Rattus norvegicus (Norway rat)	Cxcr5	NP_445755.1
Homo sapiens (human)	CXCR5	NP_001707.1
Pan troglodytes (chimpanzee)	CXCR5	XP_003313403.1
Xenopus tropicalis (tropical clawed frog)	cxcr5	XP_002932969.1
Gallus gallus (chicken)	CXCR5	NP_001026083.1
Canis lupus familiaris (dog)	CXCR5	XP_003434618.1
Mus musculus (house mouse)	Cxcr5	NP_031577.2
Danio rerio (zebrafish)	LOC100537421	XP_003200530.2

Gene Ontology
Bibliography

Related articles in PubMed

GPR18 is required for a normal CD8?? intestinal intraepithelial lymphocyte compartment.
Wang X, Sumida H, Cyster JG
The Journal of experimental medicine211(12)2351-9(2014 Nov)

Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.
Vogel KU, Edelmann SL, Jeltsch KM, Bertossi A, Heger K, Heinz GA, Z?ller J, Warth SC, Hoefig KP, Lohs C, Neff F, Kremmer E, Schick J, Repsilber D, Geerlof A, Blum H, Wurst W, Heikenw?lder M, Schmidt-Supprian M, Heissmeyer V
Immunity38(4)655-68(2013 Apr)

G protein-coupled receptors participate in cytokinesis.
Zhang X, Bedigian AV, Wang W, Eggert US
Cytoskeleton (Hoboken, N.J.)69(10)810-8(2012 Oct)

Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node development.
Luther SA, Ansel KM, Cyster JG
The Journal of experimental medicine197(9)1191-8(2003 May)

Cloning of a novel putative G-protein-coupled receptor (NLR) which is expressed in neuronal and lymphatic tissue.
Kouba M, Vanetti M, Wang X, Sch?fer M, H?llt V
FEBS letters321(2-3)173-8(1993 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cxcr5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cxcr5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09219	NM_053303.1 Latest version!	Rattus norvegicus C-X-C motif chemokine receptor 5 (Cxcr5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa31059	XM_006242901.3 Latest version!	Rattus norvegicus C-X-C motif chemokine receptor 5 (Cxcr5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cxcr5 ( NM_053303.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445755.1 Rattus norvegicus C-X-C motif chemokine receptor 5 (Cxcr5), mRNA.

Price & Availability↑

CloneID	ORa09219
Clone ID Related Accession (Same CDS sequence)	NM_053303.1
Accession Version	NM_053303.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	C-X-C chemokine receptor type 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X71463.1. ##Evidence-Data-START## Transcript exon combination :: CV074888.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689594 [ECO:0000348] ##Evidence-Data-END##

ATGAACTCCC CGATATCGCT AGACATGGGC GCCATCACCT ACAACATGGA CGATCTGTAC 
AAGGAACTGG CCATCTACAG TAACAGCACG GAGATCCCCC TACAGGACAG TATCTTCTGT 
TCTACAGAGG AGGGGCCCCT ACTGACTTCC TTTAAGACGA TATTCATGCC TGTGGCCTAC 
AGCCTCATCT TCCTCCTGGG TATGATGGGA AACATCCTCG TACTGGTAAT CCTGGAGAGG 
CACCGGCACA CTCGGAGCTC AACGGAGACC TTCCTGTTCC ACCTGGCAGT AGCCGACCTT 
CTCTTGGTCT TCATCTTGCC TTTTGCAGTG GCTGAGGGCT CTGTGGGTTG GGTCCTAGGG 
ACCTTCCTCT GCAAAACTGT GATCGCCCTG CACAAGATCA ATTTCTACTG CAGCAGCCTG 
CTGCTGGCCT GCATAGCTGT CGACCGTTAT CTGGCCATCG TCCATGCGGT CCACGCCTAC 
CGCCGCCGCC GTCTCCTCTC TATCCACATC ACCTGCTCGA CTATTTGGCT AGCCGGCTTC 
CTATTTGCCT TGCCAGAACT CCTCTTTGCC AAGGTTGTCC AACCTCATAA CAACGAGTCC 
TTACCACAGT GCATCTTCTC CCAAGAAAAT GAAGCCGAAA CTAGAGCCTG GTTCGCCTCC 
CGGTTTCTCT ACCACACTGG GGGCTTCCTG CTACCGATGC TCGTGATGGC CTGGTGTTAT 
GTGGGAGTGG TACACAGGCT ATTGCAGGCC CAGCGGCGCC CTCAGAGGCA GAAGGCAGTC 
AGGGTGGCCA TCTTGGTGAC AAGCATCTTC CTTCTCTGCT GGTCACCCTA CCACATTGTC 
ATCTTCCTCG ATACACTGGA AAGGCTGAAG GCTGTGAACA GCAGTTGCGA ATTGAGTGGC 
TACCTCTCAG TGGCTATCAC CTTATGTGAA TTCCTGGGCC TGGCTCACTG CTGTCTCAAT 
CCCATGCTCT ACACCTTCGC TGGCGTAAAG TTCCGCAGTG ACTTGTCTCG GCTTCTGACC 
AAGCTGGGCT GTGCTGGCCC GGCCTCCCTT TGTCAGCTCT TTCCGGGCTG GCGCAAGAGC 
AGTCTCTCTG AGTCAGAGAA CGCTACTTCT CTTACCACCT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445755.1
CDS	1..1125
Translation	MNSPISLDMGAITYNMDDLYKELAIYSNSTEIPLQDSIFCSTEEGPLLTSFKTIFMPVAYSLIFLLGMMGNILVLVILERHRHTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKINFYCSSLLLACIAVDRYLAIVHAVHAYRRRRLLSIHITCSTIWLAGFLFALPELLFAKVVQPHNNESLPQCIFSQENEAETRAWFASRFLYHTGGFLLPMLVMAWCYVGVVHRLLQAQRRPQRQKAVRVAILVTSIFLLCWSPYHIVIFLDTLERLKAVNSSCELSGYLSVAITLCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCAGPASLCQLFPGWRKSSLSESENATSLTTF

Target ORF information:

RefSeq Version	NM_053303.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus C-X-C motif chemokine receptor 5 (Cxcr5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053303.1

ORF Insert Sequence:

ATGAACTCCC CGATATCGCT AGACATGGGC GCCATCACCT ACAACATGGA CGATCTGTAC 
AAGGAACTGG CCATCTACAG TAACAGCACG GAGATCCCCC TACAGGACAG TATCTTCTGT 
TCTACAGAGG AGGGGCCCCT ACTGACTTCC TTTAAGACGA TATTCATGCC TGTGGCCTAC 
AGCCTCATCT TCCTCCTGGG TATGATGGGA AACATCCTCG TACTGGTAAT CCTGGAGAGG 
CACCGGCACA CTCGGAGCTC AACGGAGACC TTCCTGTTCC ACCTGGCAGT AGCCGACCTT 
CTCTTGGTCT TCATCTTGCC TTTTGCAGTG GCTGAGGGCT CTGTGGGTTG GGTCCTAGGG 
ACCTTCCTCT GCAAAACTGT GATCGCCCTG CACAAGATCA ATTTCTACTG CAGCAGCCTG 
CTGCTGGCCT GCATAGCTGT CGACCGTTAT CTGGCCATCG TCCATGCGGT CCACGCCTAC 
CGCCGCCGCC GTCTCCTCTC TATCCACATC ACCTGCTCGA CTATTTGGCT AGCCGGCTTC 
CTATTTGCCT TGCCAGAACT CCTCTTTGCC AAGGTTGTCC AACCTCATAA CAACGAGTCC 
TTACCACAGT GCATCTTCTC CCAAGAAAAT GAAGCCGAAA CTAGAGCCTG GTTCGCCTCC 
CGGTTTCTCT ACCACACTGG GGGCTTCCTG CTACCGATGC TCGTGATGGC CTGGTGTTAT 
GTGGGAGTGG TACACAGGCT ATTGCAGGCC CAGCGGCGCC CTCAGAGGCA GAAGGCAGTC 
AGGGTGGCCA TCTTGGTGAC AAGCATCTTC CTTCTCTGCT GGTCACCCTA CCACATTGTC 
ATCTTCCTCG ATACACTGGA AAGGCTGAAG GCTGTGAACA GCAGTTGCGA ATTGAGTGGC 
TACCTCTCAG TGGCTATCAC CTTATGTGAA TTCCTGGGCC TGGCTCACTG CTGTCTCAAT 
CCCATGCTCT ACACCTTCGC TGGCGTAAAG TTCCGCAGTG ACTTGTCTCG GCTTCTGACC 
AAGCTGGGCT GTGCTGGCCC GGCCTCCCTT TGTCAGCTCT TTCCGGGCTG GCGCAAGAGC 
AGTCTCTCTG AGTCAGAGAA CGCTACTTCT CTTACCACCT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cxcr5 ( XM_006242901.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006242963.1 Rattus norvegicus C-X-C motif chemokine receptor 5 (Cxcr5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa31059
Clone ID Related Accession (Same CDS sequence)	XM_006242901.3
Accession Version	XM_006242901.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	C-X-C chemokine receptor type 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242901.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTACC CACTAACCTT GGACATAGAC TCCATCACCT ACAACATGGA TGAGCTGTAC 
AAGGAACTGG CCATCTACAG TAACAGCACG GAGATCCCCC TACAGGACAG TATCTTCTGT 
TCTACAGAGG AGGGGCCCCT ACTGACTTCC TTTAAGACGA TATTCATGCC TGTGGCCTAC 
AGCCTCATCT TCCTCCTGGG TATGATGGGA AACATCCTCG TACTGGTAAT CCTGGAGAGG 
CACCGGCACA CTCGGAGCTC AACGGAGACC TTCCTGTTCC ACCTGGCAGT AGCCGACCTT 
CTCTTGGTCT TCATCTTGCC TTTTGCAGTG GCTGAGGGCT CTGTGGGTTG GGTCCTAGGG 
ACCTTCCTCT GCAAAACTGT GATCGCCCTG CACAAGATCA ATTTCTACTG CAGCAGCCTG 
CTGCTGGCCT GCATAGCTGT CGACCGTTAT CTGGCCATCG TCCATGCGGT CCACGCCTAC 
CGCCGCCGCC GTCTCCTCTC CATCCACATC ACCTGCTCGA CTATTTGGCT AGCCGGCTTC 
CTATTTGCCT TGCCAGAACT CCTCTTTGCC AAGGTTGTCC AACCTCATAA CAACGAGTCC 
TTACCACAGT GCATCTTCTC CCAAGAAAAT GAAGCCGAAA CTAGAGCCTG GTTCGCCTCC 
CGGTTTCTCT ACCACACTGG GGGCTTCCTG CTACCGATGC TCGTGATGGC CTGGTGTTAT 
GTGGGAGTGG TACACAGGCT ATTGCAGGCC CAGCGGCGCC CTCAGAGGCA GAAGGCAGTC 
AGGGTGGCCA TCTTGGTGAC AAGCATCTTC CTTCTCTGCT GGTCACCCTA CCACATTGTC 
ATCTTCCTCG ATACACTGGA AAGGCTGAAG GCTGTGAACA GCAGTTGCGA ATTGAGTGGC 
TACCTCTCGG TGGCTATCAC CTTATGTGAA TTCCTGGGCC TGGCTCACTG CTGTCTCAAT 
CCCATGCTCT ACACCTTCGC TGGCGTAAAG TTCCGCAGTG ACTTGTCTCG GCTTCTGACC 
AAGCTGGGCT GTGCTGGCCC GGCCTCCCTT TGTCAGCTCT TTCCGGGCTG GCGCAAGAGC 
AGTCTCTCTG AGTCAGAGAA CGCTACTTCT CTTACCACCT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006242963.1
CDS	618..1742
Translation	MNYPLTLDIDSITYNMDELYKELAIYSNSTEIPLQDSIFCSTEEGPLLTSFKTIFMPVAYSLIFLLGMMGNILVLVILERHRHTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKINFYCSSLLLACIAVDRYLAIVHAVHAYRRRRLLSIHITCSTIWLAGFLFALPELLFAKVVQPHNNESLPQCIFSQENEAETRAWFASRFLYHTGGFLLPMLVMAWCYVGVVHRLLQAQRRPQRQKAVRVAILVTSIFLLCWSPYHIVIFLDTLERLKAVNSSCELSGYLSVAITLCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCAGPASLCQLFPGWRKSSLSESENATSLTTF

Target ORF information:

RefSeq Version	XM_006242901.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus C-X-C motif chemokine receptor 5 (Cxcr5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006242901.3

ORF Insert Sequence:

ATGAACTACC CACTAACCTT GGACATAGAC TCCATCACCT ACAACATGGA TGAGCTGTAC 
AAGGAACTGG CCATCTACAG TAACAGCACG GAGATCCCCC TACAGGACAG TATCTTCTGT 
TCTACAGAGG AGGGGCCCCT ACTGACTTCC TTTAAGACGA TATTCATGCC TGTGGCCTAC 
AGCCTCATCT TCCTCCTGGG TATGATGGGA AACATCCTCG TACTGGTAAT CCTGGAGAGG 
CACCGGCACA CTCGGAGCTC AACGGAGACC TTCCTGTTCC ACCTGGCAGT AGCCGACCTT 
CTCTTGGTCT TCATCTTGCC TTTTGCAGTG GCTGAGGGCT CTGTGGGTTG GGTCCTAGGG 
ACCTTCCTCT GCAAAACTGT GATCGCCCTG CACAAGATCA ATTTCTACTG CAGCAGCCTG 
CTGCTGGCCT GCATAGCTGT CGACCGTTAT CTGGCCATCG TCCATGCGGT CCACGCCTAC 
CGCCGCCGCC GTCTCCTCTC CATCCACATC ACCTGCTCGA CTATTTGGCT AGCCGGCTTC 
CTATTTGCCT TGCCAGAACT CCTCTTTGCC AAGGTTGTCC AACCTCATAA CAACGAGTCC 
TTACCACAGT GCATCTTCTC CCAAGAAAAT GAAGCCGAAA CTAGAGCCTG GTTCGCCTCC 
CGGTTTCTCT ACCACACTGG GGGCTTCCTG CTACCGATGC TCGTGATGGC CTGGTGTTAT 
GTGGGAGTGG TACACAGGCT ATTGCAGGCC CAGCGGCGCC CTCAGAGGCA GAAGGCAGTC 
AGGGTGGCCA TCTTGGTGAC AAGCATCTTC CTTCTCTGCT GGTCACCCTA CCACATTGTC 
ATCTTCCTCG ATACACTGGA AAGGCTGAAG GCTGTGAACA GCAGTTGCGA ATTGAGTGGC 
TACCTCTCGG TGGCTATCAC CTTATGTGAA TTCCTGGGCC TGGCTCACTG CTGTCTCAAT 
CCCATGCTCT ACACCTTCGC TGGCGTAAAG TTCCGCAGTG ACTTGTCTCG GCTTCTGACC 
AAGCTGGGCT GTGCTGGCCC GGCCTCCCTT TGTCAGCTCT TTCCGGGCTG GCGCAAGAGC 
AGTCTCTCTG AGTCAGAGAA CGCTACTTCT CTTACCACCT TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

GPR18 is required for a normal CD8?? intestinal intraepithelial lymphocyte compartment.
The Journal of experimental medicine211(12)2351-9(2014 Nov)
Wang X,Sumida H,Cyster JG

Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.
Immunity38(4)655-68(2013 Apr)
Vogel KU,Edelmann SL,Jeltsch KM,Bertossi A,Heger K,Heinz GA,Z?ller J,Warth SC,Hoefig KP,Lohs C,Neff F,Kremmer E,Schick J,Repsilber D,Geerlof A,Blum H,Wurst W,Heikenw?lder M,Schmidt-Supprian M,Heissmeyer V

G protein-coupled receptors participate in cytokinesis.
Cytoskeleton (Hoboken, N.J.)69(10)810-8(2012 Oct)
Zhang X,Bedigian AV,Wang W,Eggert US

Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node development.
The Journal of experimental medicine197(9)1191-8(2003 May)
Luther SA,Ansel KM,Cyster JG

Cloning of a novel putative G-protein-coupled receptor (NLR) which is expressed in neuronal and lymphatic tissue.
FEBS letters321(2-3)173-8(1993 Apr)
Kouba M,Vanetti M,Wang X,Sch?fer M,H?llt V