H1f1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	H1f1
Entrez Gene ID	291145
Full Name	histone cluster 1 H1 family member a
General protein information	Preferred Names histone cluster 1 H1 family member a Names histone H1.1 histone 1, H1a histone H1a histone cluster 1, H1a
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17p11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106113.1	NP_001099583.1	histone H1.1

Pathways from BioSystems

Homologies

	HIST1H1A	XP_001083516.1
Mus musculus (house mouse)	Hist1h1a	NP_085112.1
Rattus norvegicus (Norway rat)	Hist1h1a	NP_001099583.1

Gene Ontology
Bibliography

Related articles in PubMed

Binding of histone H1 to DNA is differentially modulated by redox state of HMGB1.
Polansk? E, Posp??ilov? ?, ?tros M
PloS one9(2)e89070(2014)

Histone H1 subtype preferences of DFF40 and possible nuclear localization of DFF40/45 in normal and trichostatin A-treated NB4 leukemic cells.
Ninios YP, Sekeri-Pataryas KE, Sourlingas TG
Apoptosis : an international journal on programmed cell death15(2)128-38(2010 Feb)

H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain.
Th'ng JP, Sung R, Ye M, Hendzel MJ
The Journal of biological chemistry280(30)27809-14(2005 Jul)

Identification of the linker histone H1 as a protein kinase Cepsilon-binding protein in vascular smooth muscle.
Zhao M, Sutherland C, Wilson DP, Deng J, Macdonald JA, Walsh MP
Biochemistry and cell biology = Biochimie et biologie cellulaire82(5)538-46(2004 Oct)

The preferential binding of histone H1 to DNA scaffold-associated regions is determined by its C-terminal domain.
Roque A, Orrego M, Ponte I, Suau P
Nucleic acids research32(20)6111-9(2004)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Binding of histone H1 to DNA is differentially modulated by redox state of HMGB1.
Title: Binding of histone H1 to DNA is differentially modulated by redox state of HMGB1.

Histone H1 is both an anchoring protein and a substrate for activated PKCepsilon
Title: Identification of the linker histone H1 as a protein kinase Cepsilon-binding protein in vascular smooth muscle.

The following H1f1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the H1f1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42646	NM_001106113.1 Latest version!	Rattus norvegicus H1.1 linker histone, cluster member (H1f1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

H1f1 ( NM_001106113.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099583.1 Rattus norvegicus H1.1 linker histone, cluster member (H1f1), mRNA.

Price & Availability↑

CloneID	ORa42646
Clone ID Related Accession (Same CDS sequence)	NM_001106113.1
Accession Version	NM_001106113.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 645bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	histone H1.1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474064.1. On or before Oct 4, 2007 this sequence version replaced XM_225330.3, XM_001071190.1.

ATGTCGGAGA CAGCGCCAGT CCCTCAGCCT GCGTCTGTTG CCCCTGAGAA ACCTGCCGCT 
ACAAAGAAAA CCAGGAAGCC TGCGAAAGCT GCTGTCCCTC GAAAGAAGCC CGCGGGACCT 
TCAGTGTCTG AGCTCATCGT GCAGGCAGTC TCATCCTCCA AGGAGCGCAG CGGCGTGTCC 
TTGGCTGCGC TCAAGAAGTC GCTGGCGGCG GCGGGCTACG ATGTGGAGAA GAACAACAGC 
CGCATCAAAC TCGGGCTGAA GAGCCTGGTG AATAAGGGCA CCCTGGTGCA GACTAAGGGT 
ACCGGCGCTG CTGGCTCCTT TAAGCTGAAC AAGAAGGCGG AGTCCAAAGC CAGCACCACC 
AAGGTGACAG TGAAGGCGAA AGCATCCGGG GCAGCTAAGA AACCCAAGAA GACTGCTGGG 
GCTGCAGCAA AGAAGACTGT CAAGACACCG AAGAAGCCCA AGAAGCCTGC AGTTTCAAAG 
AAGACTTCTT CTAAGAGCCC AAAGAAGCCG AAGGTGGTCA AGGCCAAGAA GGTAGCCAAG 
AGCCCTGCCA AGGCAAAGGC AGTGAAGCCT AAGGCTGCCA AGGTGAAGGT GACAAAGCCA 
AAGACTCCAG CTAAGCCGAA GAAGGCGGCG CCCAAGAAAA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099583.1
CDS	47..691
Translation	MSETAPVPQPASVAPEKPAATKKTRKPAKAAVPRKKPAGPSVSELIVQAVSSSKERSGVSLAALKKSLAAAGYDVEKNNSRIKLGLKSLVNKGTLVQTKGTGAAGSFKLNKKAESKASTTKVTVKAKASGAAKKPKKTAGAAAKKTVKTPKKPKKPAVSKKTSSKSPKKPKVVKAKKVAKSPAKAKAVKPKAAKVKVTKPKTPAKPKKAAPKKK

Target ORF information:

RefSeq Version	NM_001106113.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus H1.1 linker histone, cluster member (H1f1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106113.1

ORF Insert Sequence:

ATGTCGGAGA CAGCGCCAGT CCCTCAGCCT GCGTCTGTTG CCCCTGAGAA ACCTGCCGCT 
ACAAAGAAAA CCAGGAAGCC TGCGAAAGCT GCTGTCCCTC GAAAGAAGCC CGCGGGACCT 
TCAGTGTCTG AGCTCATCGT GCAGGCAGTC TCATCCTCCA AGGAGCGCAG CGGCGTGTCC 
TTGGCTGCGC TCAAGAAGTC GCTGGCGGCG GCGGGCTACG ATGTGGAGAA GAACAACAGC 
CGCATCAAAC TCGGGCTGAA GAGCCTGGTG AATAAGGGCA CCCTGGTGCA GACTAAGGGT 
ACCGGCGCTG CTGGCTCCTT TAAGCTGAAC AAGAAGGCGG AGTCCAAAGC CAGCACCACC 
AAGGTGACAG TGAAGGCGAA AGCATCCGGG GCAGCTAAGA AACCCAAGAA GACTGCTGGG 
GCTGCAGCAA AGAAGACTGT CAAGACACCG AAGAAGCCCA AGAAGCCTGC AGTTTCAAAG 
AAGACTTCTT CTAAGAGCCC AAAGAAGCCG AAGGTGGTCA AGGCCAAGAA GGTAGCCAAG 
AGCCCTGCCA AGGCAAAGGC AGTGAAGCCT AAGGCTGCCA AGGTGAAGGT GACAAAGCCA 
AAGACTCCAG CTAAGCCGAA GAAGGCGGCG CCCAAGAAAA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Binding of histone H1 to DNA is differentially modulated by redox state of HMGB1.
PloS one9(2)e89070(2014)
Polansk? E,Posp??ilov? ?,?tros M

Histone H1 subtype preferences of DFF40 and possible nuclear localization of DFF40/45 in normal and trichostatin A-treated NB4 leukemic cells.
Apoptosis : an international journal on programmed cell death15(2)128-38(2010 Feb)
Ninios YP,Sekeri-Pataryas KE,Sourlingas TG

H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain.
The Journal of biological chemistry280(30)27809-14(2005 Jul)
Th'ng JP,Sung R,Ye M,Hendzel MJ

Identification of the linker histone H1 as a protein kinase Cepsilon-binding protein in vascular smooth muscle.
Biochemistry and cell biology = Biochimie et biologie cellulaire82(5)538-46(2004 Oct)
Zhao M,Sutherland C,Wilson DP,Deng J,Macdonald JA,Walsh MP

The preferential binding of histone H1 to DNA scaffold-associated regions is determined by its C-terminal domain.
Nucleic acids research32(20)6111-9(2004)
Roque A,Orrego M,Ponte I,Suau P