Adam9 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adam9
Entrez Gene ID	290834
Full Name	ADAM metallopeptidase domain 9
Synonyms	MDC9
General protein information	Preferred Names ADAM metallopeptidase domain 9 Names disintegrin and metalloproteinase domain-containing protein 9 a disintegrin and metallopeptidase domain 9 (meltrin gamma) a disintegrin and metalloproteinase domain 9 (meltrin gamma) meltrin gamma
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16q12.4

mRNA and Protein(s)

mRNA	Protein	Name
NM_001014772.1	NP_001014772.1	disintegrin and metalloproteinase domain-containing protein 9 precursor

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	ADAM9	NP_001026567.2
Mus musculus (house mouse)	Adam9	NP_031430.2
Xenopus tropicalis (tropical clawed frog)	adam9	NP_001233130.1
Homo sapiens (human)	ADAM9	NP_003807.1
Canis lupus familiaris (dog)	ADAM9	NP_001182331.1
	ADAM9	XP_001092710.1
Bos taurus (cattle)	ADAM9	NP_001179747.2
Pan troglodytes (chimpanzee)	ADAM9	XP_001135576.1
Rattus norvegicus (Norway rat)	Adam9	NP_001014772.1

Gene Ontology
Bibliography

Related articles in PubMed

Effects of aluminium on ?-amyloid (1-42) and secretases (APP-cleaving enzymes) in rat brain.
Wang L, Hu J, Zhao Y, Lu X, Zhang Q, Niu Q
Neurochemical research39(7)1338-45(2014 Jul)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

LPS activates ADAM9 dependent shedding of ACE from endothelial cells.
English WR, Corvol P, Murphy G
Biochemical and biophysical research communications421(1)70-5(2012 Apr)

Involvement of TACE/ADAM17 and ADAM10 in etoposide-induced apoptosis of germ cells in rat spermatogenesis.
Lizama C, Rojas-Benitez D, Antonelli M, Ludwig A, Moreno RD
Journal of cellular physiology227(2)829-38(2012 Feb)

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM
Nature cell biology13(4)383-93(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ADAM9 was induced in dentate gyrus of hippocampus. The spatiotemporal expression of ADAM9 suggests that its regulation after the KA-induced status epilepticus could be related to neuroprotection.
Title: ADAM9, ADAM10, and ADAM15 mRNA levels in the rat brain after kainic acid-induced status epilepticus.

The following Adam9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adam9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05608	NM_001014772.1 Latest version!	Rattus norvegicus ADAM metallopeptidase domain 9 (Adam9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adam9 ( NM_001014772.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001014772.1 Rattus norvegicus ADAM metallopeptidase domain 9 (Adam9), mRNA.

Price & Availability↑

CloneID	ORa05608
Clone ID Related Accession (Same CDS sequence)	NM_001014772.1
Accession Version	NM_001014772.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2538bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-08-03
Organism	Rattus norvegicus(Norway rat)
Product	disintegrin and metalloproteinase domain-containing protein 9 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY953138.1. On Apr 20, 2005 this sequence version replaced XM_224964.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY953138.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGGCCGC GCGCGCTCTC GCCCCTCGCC TCTCTGCGAC TAAGGTGGCT GCTGGCGTGT 
GGCTTGCTGG GCCCAGTCCT CGAGGCCGGG CGGCCAGACT CTGAACAGAC CGTCCATCTT 
TCTTCTTATG AAATTGTAAC TCCTTGGAGA TTAAGTAGAG AAAGAAGGGA AGCTCTGAGG 
CCCAGTTCAA AACAGATCTC TTATGTCATC CAGGCCCAAG GAAAACAGCA TATTATTCAC 
TTGGAAAGAA ACACAGACCT TTTACCTAAC GACTTTGTAG TTTATACCTA CGACGAGGAG 
GGCTCCCTAC TCTCTGACCA TCCCAACGTA CAGAGTCATT GCCATTACCG AGGCTATGTG 
GAGGGAGTGC CCAATTCCGC CGTTGCTGTG AGTGCCTGCT TTGGACTCAG AGGATTGCTG 
CATTTGGAGA ATGCCAGTTT TGGAATCGAA CCTCTGCACA ACAGCTCACA CTTTGAGCAC 
GTGTTTTACC CAATGGATGA TGTCCACCAG GAGCCTCTGA GATGTGGCGT CTCTAACAGG 
GACACAGAGC AGGAAGCCAC CCAGGGGGAA GAGGAAGAGC ACCCGAGCGT AACTCAGCTG 
CTGCGAAGAA GAAGAGCTGT TCTCCCGCAG ACCCGCTACG TGGAGCTGTT CATTGTTGTA 
GACAAGGAAA GGTACGACAT GATGGGAAGG AACCAGACTG CTGTGAGAGA AGAGATGATT 
CGCTTAGCAA ACTACCTGGA TAGCATGTAC ATCATGTTAA ACATTCGAAT TGTGCTAGTT 
GGACTAGAAA TTTGGACAGA TAGAAATCCT ATCAATATAA TTGGAGGAGC TGGAGATGTA 
TTGGGCAACT TTGTACAGTG GCGGGAAAAG TTTCTTATAA CACGTCGGAG ACATGACAGT 
GCACAGTTGG TTTTGAAGAA AGGCTTTGGT GGAACTGCAG GAATGGCATT TGTAGGAACA 
GTATGTTCAA GGAGCCACGC AGGTGGGATT AATGTGTTTG GGCAAATCAC CGTGGAGACA 
TTTGCGTCCA TTGTTGCTCA TGAACTGGGA CATAACCTTG GGATGAATCA TGATGATGGG 
AGAGAGTGTT TCTGTGCAGC AAAGAGCTGT ATCATGAATT CAGGAGCATC AGGGTCCAGG 
AACTTCAGCA GTTGCAGTGC AGAGGACTTT GAGAAATTAA CTTTGAACAA GGGAGGAAGC 
TGCCTGCTCA ACATCCCGAA GCCTGACGAG GCCTACAGCG CGCCCTCCTG TGGTAACAAG 
CTGGTGGACC CCGGGGAGGA GTGTGACTGT GGCACACCAA AGGAATGTGA GTTGGATCCA 
TGCTGTGAAG GAAGCACTTG TAAGCTCAAG TCATTTGCTG AGTGTGCATA TGGCGACTGT 
TGTAAAGATT GCCAGTTCCT TCCAGGAGGC TCTATGTGCA GAGGGAAGAC CAGTGAGTGT 
GATGTCCCTG AGTACTGCAA TGGCTCCTCT CAGTTCTGCC CACCCGATGT CTTCATTCAG 
AACGGCTATC CTTGTTGGAA TAGCAAAGCC TACTGTTACA ATGGCGTGTG CCAGTATTAT 
GACGCTCAGT GCCAGGTCAT CTTTGGTTCA AAAGCTAAGG CTGCCCCAAG AGATTGCTTC 
ATTGAAGTGA ATTCTAAAGG TGACAGATTT GGCAACTGTG GTGTCTCCGG CAGTAATTAC 
AAAACGTGTG CCACAGGGAA CGCGTTGTGT GGAAAGCTTC AGTGTGAGAA CGTGCAGGAG 
ATGCCGGTGT TCGGAATCGT GCCAGCTATC ATTCAGACAC CCAGCCGAGG CACCAAATGT 
TGGGGTGTGG ATTTCCAGCT TGGTTCCGAT GTCCCAGACC CAGGGATGGT GAATGAAGGC 
ACCAAATGTG ATGCTGGGAA GATTTGTAGG AATTTTCAGT GTGTAAATGC TTCTGTCCTG 
AATTATGACT GTGACATTCA GGGAAAATGT CACGGCCATG GGGTATGTAA CAGCAATAAG 
AATTGTCACT GTGAAGATGG CTGGGCTCCC CCACACTGTG ACACCAAAGG ATATGGAGGG 
AGTGTGGACA GTGGGCCGAC GTACAATGCA AAGAGCACGG CCCTGAGGGA TGGACTTCTG 
GTCTTCTTCT TCCTAATCAT CCCCCTGGTT GCGGCTGCCT TTTTCCTCTT CATCAAGAGA 
GATGAACTGA GGAAAACCTT CAGGAAGAAG AGATCACAAA TGTCAGATGG CAGAAATCAA 
GCAAATGCCT CTAGACCGCC AGGGGACCCC AGTGTCTCCA GACCACCAGG GGGTCCAAGT 
GTCTCCAGAC CACCAGGGGG CCCAAATGTC TCCAGACCAC CAGGGGGCCC AAATGTCTCC 
AGACCACCAG GGGGCCCGAG TGTCTCCAGA CCACCACCCG TGCATGGAAA CAGATTCCCA 
GTACCAACCT ATGCCATCAA GCAGCCACCA CAGTTTCCAT CAAGGCCACC TCCACCACAA 
CCGAAAATAC CTTCTCAGGG AAACTTGGTT CCGGCCCGGC CAGCTCCTGC ACCGCCTTTA 
TATAGCTCCC TCACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014772.1
CDS	28..2565
Translation	MGPRALSPLASLRLRWLLACGLLGPVLEAGRPDSEQTVHLSSYEIVTPWRLSRERREALRPSSKQISYVIQAQGKQHIIHLERNTDLLPNDFVVYTYDEEGSLLSDHPNVQSHCHYRGYVEGVPNSAVAVSACFGLRGLLHLENASFGIEPLHNSSHFEHVFYPMDDVHQEPLRCGVSNRDTEQEATQGEEEEHPSVTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMIRLANYLDSMYIMLNIRIVLVGLEIWTDRNPINIIGGAGDVLGNFVQWREKFLITRRRHDSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDGRECFCAAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGSCLLNIPKPDEAYSAPSCGNKLVDPGEECDCGTPKECELDPCCEGSTCKLKSFAECAYGDCCKDCQFLPGGSMCRGKTSECDVPEYCNGSSQFCPPDVFIQNGYPCWNSKAYCYNGVCQYYDAQCQVIFGSKAKAAPRDCFIEVNSKGDRFGNCGVSGSNYKTCATGNALCGKLQCENVQEMPVFGIVPAIIQTPSRGTKCWGVDFQLGSDVPDPGMVNEGTKCDAGKICRNFQCVNASVLNYDCDIQGKCHGHGVCNSNKNCHCEDGWAPPHCDTKGYGGSVDSGPTYNAKSTALRDGLLVFFFLIIPLVAAAFFLFIKRDELRKTFRKKRSQMSDGRNQANASRPPGDPSVSRPPGGPSVSRPPGGPNVSRPPGGPNVSRPPGGPSVSRPPPVHGNRFPVPTYAIKQPPQFPSRPPPPQPKIPSQGNLVPARPAPAPPLYSSLT

Target ORF information:

RefSeq Version	NM_001014772.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ADAM metallopeptidase domain 9 (Adam9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014772.1

ORF Insert Sequence:

ATGGGGCCGC GCGCGCTCTC GCCCCTCGCC TCTCTGCGAC TAAGGTGGCT GCTGGCGTGT 
GGCTTGCTGG GCCCAGTCCT CGAGGCCGGG CGGCCAGACT CTGAACAGAC CGTCCATCTT 
TCTTCTTATG AAATTGTAAC TCCTTGGAGA TTAAGTAGAG AAAGAAGGGA AGCTCTGAGG 
CCCAGTTCAA AACAGATCTC TTATGTCATC CAGGCCCAAG GAAAACAGCA TATTATTCAC 
TTGGAAAGAA ACACAGACCT TTTACCTAAC GACTTTGTAG TTTATACCTA CGACGAGGAG 
GGCTCCCTAC TCTCTGACCA TCCCAACGTA CAGAGTCATT GCCATTACCG AGGCTATGTG 
GAGGGAGTGC CCAATTCCGC CGTTGCTGTG AGTGCCTGCT TTGGACTCAG AGGATTGCTG 
CATTTGGAGA ATGCCAGTTT TGGAATCGAA CCTCTGCACA ACAGCTCACA CTTTGAGCAC 
GTGTTTTACC CAATGGATGA TGTCCACCAG GAGCCTCTGA GATGTGGCGT CTCTAACAGG 
GACACAGAGC AGGAAGCCAC CCAGGGGGAA GAGGAAGAGC ACCCGAGCGT AACTCAGCTG 
CTGCGAAGAA GAAGAGCTGT TCTCCCGCAG ACCCGCTACG TGGAGCTGTT CATTGTTGTA 
GACAAGGAAA GGTACGACAT GATGGGAAGG AACCAGACTG CTGTGAGAGA AGAGATGATT 
CGCTTAGCAA ACTACCTGGA TAGCATGTAC ATCATGTTAA ACATTCGAAT TGTGCTAGTT 
GGACTAGAAA TTTGGACAGA TAGAAATCCT ATCAATATAA TTGGAGGAGC TGGAGATGTA 
TTGGGCAACT TTGTACAGTG GCGGGAAAAG TTTCTTATAA CACGTCGGAG ACATGACAGT 
GCACAGTTGG TTTTGAAGAA AGGCTTTGGT GGAACTGCAG GAATGGCATT TGTAGGAACA 
GTATGTTCAA GGAGCCACGC AGGTGGGATT AATGTGTTTG GGCAAATCAC CGTGGAGACA 
TTTGCGTCCA TTGTTGCTCA TGAACTGGGA CATAACCTTG GGATGAATCA TGATGATGGG 
AGAGAGTGTT TCTGTGCAGC AAAGAGCTGT ATCATGAATT CAGGAGCATC AGGGTCCAGG 
AACTTCAGCA GTTGCAGTGC AGAGGACTTT GAGAAATTAA CTTTGAACAA GGGAGGAAGC 
TGCCTGCTCA ACATCCCGAA GCCTGACGAG GCCTACAGCG CGCCCTCCTG TGGTAACAAG 
CTGGTGGACC CCGGGGAGGA GTGTGACTGT GGCACACCAA AGGAATGTGA GTTGGATCCA 
TGCTGTGAAG GAAGCACTTG TAAGCTCAAG TCATTTGCTG AGTGTGCATA TGGCGACTGT 
TGTAAAGATT GCCAGTTCCT TCCAGGAGGC TCTATGTGCA GAGGGAAGAC CAGTGAGTGT 
GATGTCCCTG AGTACTGCAA TGGCTCCTCT CAGTTCTGCC CACCCGATGT CTTCATTCAG 
AACGGCTATC CTTGTTGGAA TAGCAAAGCC TACTGTTACA ATGGCGTGTG CCAGTATTAT 
GACGCTCAGT GCCAGGTCAT CTTTGGTTCA AAAGCTAAGG CTGCCCCAAG AGATTGCTTC 
ATTGAAGTGA ATTCTAAAGG TGACAGATTT GGCAACTGTG GTGTCTCCGG CAGTAATTAC 
AAAACGTGTG CCACAGGGAA CGCGTTGTGT GGAAAGCTTC AGTGTGAGAA CGTGCAGGAG 
ATGCCGGTGT TCGGAATCGT GCCAGCTATC ATTCAGACAC CCAGCCGAGG CACCAAATGT 
TGGGGTGTGG ATTTCCAGCT TGGTTCCGAT GTCCCAGACC CAGGGATGGT GAATGAAGGC 
ACCAAATGTG ATGCTGGGAA GATTTGTAGG AATTTTCAGT GTGTAAATGC TTCTGTCCTG 
AATTATGACT GTGACATTCA GGGAAAATGT CACGGCCATG GGGTATGTAA CAGCAATAAG 
AATTGTCACT GTGAAGATGG CTGGGCTCCC CCACACTGTG ACACCAAAGG ATATGGAGGG 
AGTGTGGACA GTGGGCCGAC GTACAATGCA AAGAGCACGG CCCTGAGGGA TGGACTTCTG 
GTCTTCTTCT TCCTAATCAT CCCCCTGGTT GCGGCTGCCT TTTTCCTCTT CATCAAGAGA 
GATGAACTGA GGAAAACCTT CAGGAAGAAG AGATCACAAA TGTCAGATGG CAGAAATCAA 
GCAAATGCCT CTAGACCGCC AGGGGACCCC AGTGTCTCCA GACCACCAGG GGGTCCAAGT 
GTCTCCAGAC CACCAGGGGG CCCAAATGTC TCCAGACCAC CAGGGGGCCC AAATGTCTCC 
AGACCACCAG GGGGCCCGAG TGTCTCCAGA CCACCACCCG TGCATGGAAA CAGATTCCCA 
GTACCAACCT ATGCCATCAA GCAGCCACCA CAGTTTCCAT CAAGGCCACC TCCACCACAA 
CCGAAAATAC CTTCTCAGGG AAACTTGGTT CCGGCCCGGC CAGCTCCTGC ACCGCCTTTA 
TATAGCTCCC TCACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effects of aluminium on ?-amyloid (1-42) and secretases (APP-cleaving enzymes) in rat brain.
Neurochemical research39(7)1338-45(2014 Jul)
Wang L,Hu J,Zhao Y,Lu X,Zhang Q,Niu Q

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

LPS activates ADAM9 dependent shedding of ACE from endothelial cells.
Biochemical and biophysical research communications421(1)70-5(2012 Apr)
English WR,Corvol P,Murphy G

Involvement of TACE/ADAM17 and ADAM10 in etoposide-induced apoptosis of germ cells in rat spermatogenesis.
Journal of cellular physiology227(2)829-38(2012 Feb)
Lizama C,Rojas-Benitez D,Antonelli M,Ludwig A,Moreno RD

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Nature cell biology13(4)383-93(2011 Apr)
Kuo JC,Han X,Hsiao CT,Yates JR 3rd,Waterman CM