Wrap53 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Wrap53
Entrez Gene ID	287432
Full Name	WD repeat containing, antisense to TP53
Synonyms	Wdr79
General protein information	Preferred Names WD repeat containing, antisense to TP53 Names telomerase Cajal body protein 1 WD repeat domain 79 WD repeat-containing protein 79 WD repeat-containing protein WRAP53 WD40 repeat-containing protein antisense to TP53 WD40 repeat-containing protein encoded by RNA antisense to p53
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007610.1	NP_001007611.1	telomerase Cajal body protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	WRAP53	NP_001137462.1
Pan troglodytes (chimpanzee)	WRAP53	XP_001172037.1
Bos taurus (cattle)	WRAP53	NP_001030245.1
Mus musculus (house mouse)	Wrap53	NP_659073.1
Danio rerio (zebrafish)	wrap53	NP_001242957.1
Drosophila melanogaster (fruit fly)	WDR79	NP_608997.3
Arabidopsis thaliana (thale cress)	AT4G21520	NP_193883.2
Canis lupus familiaris (dog)	WRAP53	XP_005620047.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001885	XP_001689316.2
Rattus norvegicus (Norway rat)	Wrap53	NP_001007611.1
Oryza sativa (rice)	Os03g0738000	NP_001051207.1
	WRAP53	XP_001110427.1

Gene Ontology
Bibliography

Related articles in PubMed

Phosphorylation of the Cajal body protein WRAP53? by ATM promotes its involvement in the DNA damage response.
Coucoravas C, Dhanjal S, Henriksson S, B?hm S, Farnebo M
RNA biology14(6)804-813(2017 Jun)

Dynamics of Human Telomerase Holoenzyme Assembly and Subunit Exchange across the Cell Cycle.
Vogan JM, Collins K
The Journal of biological chemistry290(35)21320-35(2015 Aug)

The proximity ligation assay reveals that at DNA double-strand breaks WRAP53? associates with ?H2AX and controls interactions between RNF8 and MDC1.
Rassoolzadeh H, Coucoravas C, Farnebo M
Nucleus (Austin, Tex.)6(5)417-24(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Wrap53 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wrap53 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11119	NM_001007610.1 Latest version!	Rattus norvegicus WD repeat containing, antisense to TP53 (Wrap53), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$314.30 $449.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Wrap53 ( NM_001007610.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001007611.1 Rattus norvegicus WD repeat containing, antisense to TP53 (Wrap53), mRNA.

Price & Availability↑

CloneID	ORa11119
Clone ID Related Accession (Same CDS sequence)	NM_001007610.1
Accession Version	NM_001007610.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	telomerase Cajal body protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083696.1. On Nov 29, 2004 this sequence version replaced XM_213366.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC083696.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906352 [ECO:0000348] ##Evidence-Data-END##

ATGAAGACGT CGGAGGAGCT ACGCCTAGCT CCGGATAGCC TCCCTTCTGA CCTGGTCCCA 
GCCCCAGTGC TCCAAGCTTC CCCCGCGGAC AAAAATACAG ACTCTGAACC GGTGCCTCCG 
CCATGCGGTG GAGATGACCA ACTCCAGGTA GCCACAGATG CCGTGGCCAG CTCGGTTGTG 
TCCCAGGAGC TTCAACAAGG GGACTCAGCT CCTCTGGAAG TAGAATTTAA TATTTCCAGT 
GAGTTGAGTC CTCGAATCGA GGAGCAAGAA GTTCCTGAAA ATGCCAGCCT TCCTGTAGAA 
GAAACGAATC GGCCCGAGTT GGAGTCAGGG GAAGCCATGG AAGGTGTGTC TGAGGAACCC 
GCTGCAGTGG ATGAGGGGGA CATCTTTTGG AGCTACAGCT TCTCTCAGGT ACCCCAATAC 
CTCAGTGGCT CCTGGTCCGA GTTCAGCACC CGCTCCGAGA ACTTCTTGAA AGGTTGCAAG 
TGGGCCCCTG ACGGTTCCTG TATCTTGACC AATAGTGCTG ACAATGTCCT ACGGATTTAC 
AACCTGCCCC CAGAACTGTA CAGTGAAAGC GAGCAGGTGG ATTATGCCGA AATGGTTCCT 
GTCCTGCGAA TGGTAGAGGG TGACACCATC TATGATTACT GCTGGTATTC TCTGATGTCC 
TCCACCCAGC CAGACACCTC CTATGTGGCC AGCAGCAGCC GGGAGAACCC AATTCACATC 
TGGGATGCAT TCACTGGAGA ACTCCGGGCT TCCTTTCGCG CTTACAACCA CCTGGACGAG 
TTGACAGCGG CCCACTCACT CTGTTTCTCC CCGGATGGTT CCCAACTCTT TTGTGGCTTC 
AACCGGACTG TGCGTGTCTT TTCCACATCC AGGCCTGGCA GAGACTGTGA GGTGCGAACC 
ACATTTGCCA AAAAGCAGGG CCAGAGTGGC ATCATCTCCT GTCTAGCCTT TAGTCCAGCC 
CAGCCCCTCT ATGCCTGTGG CTCCTATGGC CGCACCCTGG GCCTGTATGC CTGGGATGAT 
GGTTCACCTC TTGCCTTGCT GGGGGGCCAT CAAGGAGGTA TCACCCACCT TTGCTTTCAC 
CCTGATGGCA ACCTCTTCTT CTCAGGAGCC CGAAAGGATG CTGAACTTCT GTGCTGGGAT 
CTCCGGCAGC CGGGCCACCT CCTGTGGTCT CTGAGTCGGG AAGTGACCAC CAATCAGCGC 
ATCTACTTTG ATCTGGACCC GAGCGGGCAG TTCCTAGTGA GTGGCAACAC CAGTGGAGTT 
GTCTCCGTGT GGGACATCAG TGGAGCGTTC AGTGACTGCA AGCAGCTGGA GCCAGTGATG 
ACTTTTCTGC CCCAGGACGA CTGCACCAAT GGAGTCAGCC TTCACCCTAC CTTGCCTCTG 
CTGGCCACTG CTTCTGGCCA GCGCATGTTT CCAGAGCCCA CCAATAGCGG GGATGAAGGT 
GAGCCGGAGC TGGACCTTCC CCTGCTCTCC CTGCGCCACG CCCATCCTGA ATGTCAGCTA 
CAGCTCTGGT GGTGTGGAGG GGGACCTGAC CCCAGTAACC CTGATGAGGA CCAGGATGAG 
AAGGGACAAG GAAGGACAGA GGCTGTCGGA ATGAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007611.1
CDS	141..1739
Translation	MKTSEELRLAPDSLPSDLVPAPVLQASPADKNTDSEPVPPPCGGDDQLQVATDAVASSVVSQELQQGDSAPLEVEFNISSELSPRIEEQEVPENASLPVEETNRPELESGEAMEGVSEEPAAVDEGDIFWSYSFSQVPQYLSGSWSEFSTRSENFLKGCKWAPDGSCILTNSADNVLRIYNLPPELYSESEQVDYAEMVPVLRMVEGDTIYDYCWYSLMSSTQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTSRPGRDCEVRTTFAKKQGQSGIISCLAFSPAQPLYACGSYGRTLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNLFFSGARKDAELLCWDLRQPGHLLWSLSREVTTNQRIYFDLDPSGQFLVSGNTSGVVSVWDISGAFSDCKQLEPVMTFLPQDDCTNGVSLHPTLPLLATASGQRMFPEPTNSGDEGEPELDLPLLSLRHAHPECQLQLWWCGGGPDPSNPDEDQDEKGQGRTEAVGMS

Target ORF information:

RefSeq Version	NM_001007610.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WD repeat containing, antisense to TP53 (Wrap53), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007610.1

ORF Insert Sequence:

ATGAAGACGT CGGAGGAGCT ACGCCTAGCT CCGGATAGCC TCCCTTCTGA CCTGGTCCCA 
GCCCCAGTGC TCCAAGCTTC CCCCGCGGAC AAAAATACAG ACTCTGAACC GGTGCCTCCG 
CCATGCGGTG GAGATGACCA ACTCCAGGTA GCCACAGATG CCGTGGCCAG CTCGGTTGTG 
TCCCAGGAGC TTCAACAAGG GGACTCAGCT CCTCTGGAAG TAGAATTTAA TATTTCCAGT 
GAGTTGAGTC CTCGAATCGA GGAGCAAGAA GTTCCTGAAA ATGCCAGCCT TCCTGTAGAA 
GAAACGAATC GGCCCGAGTT GGAGTCAGGG GAAGCCATGG AAGGTGTGTC TGAGGAACCC 
GCTGCAGTGG ATGAGGGGGA CATCTTTTGG AGCTACAGCT TCTCTCAGGT ACCCCAATAC 
CTCAGTGGCT CCTGGTCCGA GTTCAGCACC CGCTCCGAGA ACTTCTTGAA AGGTTGCAAG 
TGGGCCCCTG ACGGTTCCTG TATCTTGACC AATAGTGCTG ACAATGTCCT ACGGATTTAC 
AACCTGCCCC CAGAACTGTA CAGTGAAAGC GAGCAGGTGG ATTATGCCGA AATGGTTCCT 
GTCCTGCGAA TGGTAGAGGG TGACACCATC TATGATTACT GCTGGTATTC TCTGATGTCC 
TCCACCCAGC CAGACACCTC CTATGTGGCC AGCAGCAGCC GGGAGAACCC AATTCACATC 
TGGGATGCAT TCACTGGAGA ACTCCGGGCT TCCTTTCGCG CTTACAACCA CCTGGACGAG 
TTGACAGCGG CCCACTCACT CTGTTTCTCC CCGGATGGTT CCCAACTCTT TTGTGGCTTC 
AACCGGACTG TGCGTGTCTT TTCCACATCC AGGCCTGGCA GAGACTGTGA GGTGCGAACC 
ACATTTGCCA AAAAGCAGGG CCAGAGTGGC ATCATCTCCT GTCTAGCCTT TAGTCCAGCC 
CAGCCCCTCT ATGCCTGTGG CTCCTATGGC CGCACCCTGG GCCTGTATGC CTGGGATGAT 
GGTTCACCTC TTGCCTTGCT GGGGGGCCAT CAAGGAGGTA TCACCCACCT TTGCTTTCAC 
CCTGATGGCA ACCTCTTCTT CTCAGGAGCC CGAAAGGATG CTGAACTTCT GTGCTGGGAT 
CTCCGGCAGC CGGGCCACCT CCTGTGGTCT CTGAGTCGGG AAGTGACCAC CAATCAGCGC 
ATCTACTTTG ATCTGGACCC GAGCGGGCAG TTCCTAGTGA GTGGCAACAC CAGTGGAGTT 
GTCTCCGTGT GGGACATCAG TGGAGCGTTC AGTGACTGCA AGCAGCTGGA GCCAGTGATG 
ACTTTTCTGC CCCAGGACGA CTGCACCAAT GGAGTCAGCC TTCACCCTAC CTTGCCTCTG 
CTGGCCACTG CTTCTGGCCA GCGCATGTTT CCAGAGCCCA CCAATAGCGG GGATGAAGGT 
GAGCCGGAGC TGGACCTTCC CCTGCTCTCC CTGCGCCACG CCCATCCTGA ATGTCAGCTA 
CAGCTCTGGT GGTGTGGAGG GGGACCTGAC CCCAGTAACC CTGATGAGGA CCAGGATGAG 
AAGGGACAAG GAAGGACAGA GGCTGTCGGA ATGAGTTAA