Tnr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tnr
Entrez Gene ID	25567
Full Name	tenascin R
Synonyms	J1NRM
General protein information	Preferred Names tenascin R Names tenascin-R TN-R Tenascin-R (Restrictin, janusin, J1-160/180) janusin neural recognition molecule J1-160/180 restrictin tenascin R (restrictin, janusin)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q22
Summary	an extracellular matrix protein; involved in regulating neurite outgrowth [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013045.1	NP_037177.1	tenascin-R precursor

Pathways from BioSystems

Homologies

	TNR	XP_001104570.1
Bos taurus (cattle)	TNR	NP_001192857.1
Xenopus tropicalis (tropical clawed frog)	tnr	NP_001107287.1
Rattus norvegicus (Norway rat)	Tnr	NP_037177.1
Pan troglodytes (chimpanzee)	TNR	XP_524977.2
Mus musculus (house mouse)	Tnr	NP_071707.2
Homo sapiens (human)	TNR	NP_003276.3
Canis lupus familiaris (dog)	TNR	XP_547454.2
Gallus gallus (chicken)	TNR	NP_990607.2
Danio rerio (zebrafish)	tnr	NP_919364.1

Gene Ontology
Bibliography

Related articles in PubMed

Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats.
Cowley AW Jr, Moreno C, Jacob HJ, Peterson CB, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Reddy P, Lazar J, Evans L, Yang C, Kurth T, Liang M
Physiological genomics46(11)398-410(2014 Jun)

Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway.
Czopka T, Von Holst A, Schmidt G, Ffrench-Constant C, Faissner A
Glia57(16)1790-801(2009 Dec)

Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS.
Bekku Y, Rauch U, Ninomiya Y, Oohashi T
Journal of neurochemistry108(5)1266-76(2009 Mar)

Beta 1 integrin-mediated effects of tenascin-R domains EGFL and FN6-8 on neural stem/progenitor cell proliferation and differentiation in vitro.
Liao H, Huang W, Schachner M, Guan Y, Guo J, Yan J, Qin J, Bai X, Zhang L
The Journal of biological chemistry283(41)27927-36(2008 Oct)

Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin-R in the rat spinal cord.
Galtrey CM, Kwok JC, Carulli D, Rhodes KE, Fawcett JW
The European journal of neuroscience27(6)1373-90(2008 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Compared tenascin C and tenascin R in oligodendrocyte differentiation. Tnc and Tnr play antagonistic roles for differentiation and comparably inhibit morphologic maturation. conclude that independent molecular pathways regulate these processes.
Title: Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway.

Beta 1 integrin-mediated effects of tenascin-R domains EGFL and FN6-8 on neural stem/progenitor cell proliferation and differentiation in vitro
Title: Beta 1 integrin-mediated effects of tenascin-R domains EGFL and FN6-8 on neural stem/progenitor cell proliferation and differentiation in vitro.

Perineuronal nets in the spinal cord are discovered as a site for synthesis of tenascin-R around many neuronal cell bodies and dendrites late in development.
Title: Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin-R in the rat spinal cord.

TN-R plays a role in neuroprotection through distinct domains coordinating to modulate microglia function
Title: Tenascin-R plays a role in neuroprotection via its distinct domains that coordinate to modulate the microglia function.

An up-regulation of granular tenascin-R is found within pyramidal cells following epileptic seizure which parallels the degree of pyramidal cell loss, mossy fiber sprouting and astrogliosis.
Title: Up-regulation of the extracellular matrix glycoprotein tenascin-R during axonal reorganization and astrogliosis in the adult rat hippocampus.

The following Tnr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tnr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01762	NM_013045.1 Latest version!	Rattus norvegicus tenascin R (Tnr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$1000.30 $1429.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tnr ( NM_013045.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037177.1 Rattus norvegicus tenascin R (Tnr), mRNA.

Price & Availability↑

CloneID	ORa01762
Clone ID Related Accession (Same CDS sequence)	NM_013045.1
Accession Version	NM_013045.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	tenascin-R precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Z18630.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Z18630.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGGATCG AAGGGGAAAC AGTAGTCTTG AAGAACATGC TCATTGGTGT AAACCTGATC 
CTGTTGGGAT CCATGCTCAA GCCTTCTGAA TGCCGGCTGG AAGTGACTAC AGAAAGGGTC 
CAGAGACAAA CTGTGGAGGA GGAAGGAGGG GCTTCCAGCT ACAACACATC CAGCAAGGAA 
CAGCCTATGG TCTTTAACCA TGTGTATAAC ATCAACGTGC CACTCGAAAG CCTCTGCTCC 
TCGGGGCTGG AGGCCTCAGC TGAGCAGGAC GTGAGTGCCG AAGATGATAC TCTGGCAGAA 
TACACAGGCC AAACCTCAGA CCATGAAAGC CAGGTCACCT TCACCCACAA GATCAACCTC 
CCCAAAAAAG CCTGCCCATG TGCAAGCTCT GCCCAGGTAC TGCAGGAACT GTTGAGCCGA 
ATCGAGATGC TGGAGAGGGA GGTGTCAGTG CTGCGAGACC AGTGCAACAC CAACTGCTGT 
CAGGAAAGTG CTGCCACAGG ACAACTGGAC TATGTCCCTC ACTGCAGCGG CCATGGCAAC 
TTTAGCTTCG AGTCCTGTGG CTGCATCTGC AATGAAGGCT GGTTTGGCAA GAACTGCTCA 
GAGCCCTACT GCCCATTGGG CTGCTCCAGT CGGGGTGTAT GTGTCGATGG CCAGTGCATT 
TGTGACAGTG AATACAGCGG AGATGACTGT TCAGAGCTCC GGTGCCCAAC AGACTGCAGT 
TCCCGAGGGC TCTGTGTGGA TGGGGAATGT GTCTGTGAAG AGCCCTACAC AGGCGAGGAC 
TGCAGGGAGC TGCGTTGCCC TGGGGACTGT TCAGGGAAGG GGCAATGTGC CAATGGTACC 
TGCCTGTGCC AAGAGGGCTA TGCTGGTGAG GACTGCAGTC AGCGACGGTG TCTGAATGCT 
TGCAGTGGGC GAGGTCACTG CCAGGAGGGG CTCTGCATCT GTGAGGAGGG CTACCAGGGC 
CCTGACTGCT CAGCAGTTAC CCCTCCAGAG GACTTGCGAG TGGCTGGTAT CAGCGACAGG 
TCCATTGAGC TGGAATGGGA CGGGCCGATG GCAGTGACGG AATATGTGAT CTCTTACCAG 
CCGAGCCTGG GGGGCCTTCA GCTCCAGCAG CGGGTGCCTG GAGATTGGAG TGGTGTCACC 
ATCACGGAGC TGGAGCCAGG TCTCACCTAC AACATCAGCG TCTACGCTGT CATTAGCAAC 
ATCCTCAGCC TTCCCATCAC TGCCAAGGTG GCCACTCATC TTTCTACTCC TCAAGGGCTA 
CAGTTCAAGA CGATCACAGA GACCACCGTG GAAGTGCAGT GGGAGCCCTT CTCTTTCTCC 
TTCGATGGGT GGGAGATCAG CTTCACTCCA AAGAACAATG AAGGAGGGGT GATAGCTCAG 
CTCCCCAGCG ATGTTACGTC CTTTAACCAA ACGGGACTGA AACCTGGGGA GGAGTACATT 
GTGAATGTTG TAGCACTAAA GGAACAAGCC CGGGGCCCTC CGACCTCTGC CAGCGTCTCC 
ACTGTCATTG ACGGGCCCAC ACAGATCCTG GTTCGAGATG TCTCTGATAC TGTGGCCTTT 
GTGGAATGGA CCCCACCTCG AGCCAAAGTT GATTTCATTC TATTAAAATA TGGCTTGGTG 
GGTGGCGAAG GTGGGAAGAC TACCTTCCGG CTGCAGCCTC CCCTTAGCCA GTACTCAGTG 
CAAGCCCTTA GACCTGGCTC CCGCTACGAG GTGTCCATCA GCGCAGTCCG GGGGACCAAT 
GAAAGTGATG CCTCAAGCAC CCAGTTTACA ACAGAAATTG ATGCTCCCAA GAATTTGCGA 
GTGGGTTCCC GGACAGCAAC TAGCCTTGAC CTCGAATGGG ATAACAGCGA GGCTGAAGCT 
CAGGAGTACA AGGTTGTGTA CAGCACCCTA GCCGGGGAGC AGTACCATGA AGTGCTGGTA 
CCCAAAGGCA TTGGTCCAAC TACCAAGACT ACCCTCACAG ATCTGGTTCC AGGCACAGAA 
TATGGAGTTG GAATATCTGC GGTAATGAAC TCGAAACAAA GCATTCCCGC TACCATGAAT 
GCCAGGACTG AGCTTGACAG TCCCCGAGAC CTCATGGTAA CAGCTTCCTC AGAGACCTCT 
ATCTCTCTCA TCTGGACGAA GGCCAGTGGT CCTATTGATC ACTATCGAAT TACTTTTACT 
CCATCTTCTG GGATCTCCTC AGAAGTCACT GTGCCTAGGG ATAGGACTTC ATATACACTG 
ACAGATCTAG AGCCTGGAGC AGAATACATC ATCTCCATTA CTGCTGAGAG GGGTCGGCAG 
CAGAGCCTGG AGTCTACTGT GGATGCCTTC ACAGGCTTCC GCCCTATCTC CCACTTGCAC 
TTTTCTCATG TGACCTCCTC CAGTGTCAAC ATCACCTGGA GTGACCCATC TCCCCCAGCA 
GACAGACTCA TTCTGAACTA CAGCCCCAGG GATGAAGAGG AGGAGATGAT GGAGGTTCTC 
TTGGATGCCA CCAAGAGGCA CGCCGTCCTA ATGGGTCTAC AGCCAGCCAC TGAATATATA 
GTGAATCTCG TAGCTGTCCA TGGGACAGTA ACCTCTGAAC CCATAGTGGG TTCTATCACT 
ACAGGAATTG ATCCTCCCAA AAACATCACA ATTAGCAACG TGACTAAGGA CTCCCTGACA 
GTTTCCTGGA GCCCTCCTGT TGCGCCTTTT GATTACTACG AGTATCCTAT CGACCACCCA 
AGTGGACGGC TGGACAGCTC TGTCGTGCCC AACACTGTGA CAGAGTTCAC AATCACCAGG 
CTCTATCCAG CTAGTCAATA TGAAATAAGC CTCAACAGTG TACGCGGGAG GGAGGAGAGT 
GAACGCATCT GCACCCTGGT GCACACAGCC ATGGATAGCC CCATGGATCT AATTGCTACC 
AACATCACGC CAACAGAAGC CCTGCTCCAG TGGAAGGCAC CCATGGGTGA AGTGGAAAAT 
TATGTCATTG TCCTCACCCA CTTTGCCATG GCTGGAGAGA CCATCCTGGT TGATGGGGTC 
AGTGAAGAAT TCCAGCTTGT AGACCTGCTT CCTAGGACCC ACTACACTGT CACCATGTAT 
GCTACCAGTG GACCTCTCGT GAGTGGCACC ATCGCCACCA ACTTCTCCAC CCTCCTGGAC 
CCTCCCGCCA ACCTGACAGC CAGTGAAGTC ACCAGGCAAA GCGCACTGAT CTCCTGGCAG 
CCACCCAGAG CTGCGATTGA AAACTATGTC TTGACATACA AGTCCACCGA TGGAAGCCGC 
AAGGAGCTGA TTGTGGATGC TGAGGACACC TGGATCCGAC TGGAGGGCCT GTCGGAGAAC 
ACAGACTACA CAGTGCTCCT GCAGGCAGCT CAGGAGGCCA CAAGGAGCAG CCTCACCTCT 
ACTATCTTTA CCACAGGGGG CCGGGTGTTC TCTCATCCTC AAGACTGTGC CCAGCACTTG 
ATGAATGGAG ACACTCTGAG TGGAGTTTAC ACCATCTTCC TCAATGGGGA GTTAAGCCAC 
AAGTTGCAAG TATACTGCGA TATGACCACA GATGGGGGCG GCTGGATTGT TTTCCAGAGA 
CGGCAAAATG GCCAAACTGA TTTTTTCCGG AAATGGGCAG ATTACCGTGT TGGCTTTGGG 
AATCTGGAGG ATGAGTTTTG GCTAGGGCTA GACAACTACC ACAGGATAAC AGCCCAGGGC 
CGCTATGAGC TGCGTGTGGA TATGCGGGAT GGACAGGAGG CCGTCTTTGC CTACTATGAC 
AAGTTCGCTG TGGAGGACAG CAGAAGCCTG TACAAGCTCC GTATAGGAGG CTACAATGGC 
ACTGCAGGAG ACTCCCTTAG CTATCACCAG GGACGTCCTT TCTCCACTGA GGACAGAGAC 
AATGATGTTG CAGTCACCAA CTGTGCCATG TCATACAAGG GTGCTTGGTG GTATAAGAAC 
TGCCACCGGA CCAACCTCAA CGGGAAGTAT GGGGAGTCCA GGCACAGTCA GGGGATCAAC 
TGGTACCATT GGAAAGGCCA TGAATTCTCC ATCCCCTTTG TAGAAATGAA GATGAGGCCC 
TACATCCATC GTCTCACAGC CGGGAGGAAA CGGCGAGCCT TGAAATTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037177.1
CDS	159..4229
Translation	MGIEGETVVLKNMLIGVNLILLGSMLKPSECRLEVTTERVQRQTVEEEGGASSYNTSSKEQPMVFNHVYNINVPLESLCSSGLEASAEQDVSAEDDTLAEYTGQTSDHESQVTFTHKINLPKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNTNCCQESAATGQLDYVPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGQCANGTCLCQEGYAGEDCSQRRCLNACSGRGHCQEGLCICEEGYQGPDCSAVTPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPSLGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFTPKNNEGGVIAQLPSDVTSFNQTGLKPGEEYIVNVVALKEQARGPPTSASVSTVIDGPTQILVRDVSDTVAFVEWTPPRAKVDFILLKYGLVGGEGGKTTFRLQPPLSQYSVQALRPGSRYEVSISAVRGTNESDASSTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTLTDLVPGTEYGVGISAVMNSKQSIPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGISSEVTVPRDRTSYTLTDLEPGAEYIISITAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVLLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKNITISNVTKDSLTVSWSPPVAPFDYYEYPIDHPSGRLDSSVVPNTVTEFTITRLYPASQYEISLNSVRGREESERICTLVHTAMDSPMDLIATNITPTEALLQWKAPMGEVENYVIVLTHFAMAGETILVDGVSEEFQLVDLLPRTHYTVTMYATSGPLVSGTIATNFSTLLDPPANLTASEVTRQSALISWQPPRAAIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLSENTDYTVLLQAAQEATRSSLTSTIFTTGGRVFSHPQDCAQHLMNGDTLSGVYTIFLNGELSHKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLDNYHRITAQGRYELRVDMRDGQEAVFAYYDKFAVEDSRSLYKLRIGGYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMRPYIHRLTAGRKRRALKF

Target ORF information:

RefSeq Version	NM_013045.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tenascin R (Tnr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013045.1

ORF Insert Sequence:

ATGGGGATCG AAGGGGAAAC AGTAGTCTTG AAGAACATGC TCATTGGTGT AAACCTGATC 
CTGTTGGGAT CCATGCTCAA GCCTTCTGAA TGCCGGCTGG AAGTGACTAC AGAAAGGGTC 
CAGAGACAAA CTGTGGAGGA GGAAGGAGGG GCTTCCAGCT ACAACACATC CAGCAAGGAA 
CAGCCTATGG TCTTTAACCA TGTGTATAAC ATCAACGTGC CACTCGAAAG CCTCTGCTCC 
TCGGGGCTGG AGGCCTCAGC TGAGCAGGAC GTGAGTGCCG AAGATGATAC TCTGGCAGAA 
TACACAGGCC AAACCTCAGA CCATGAAAGC CAGGTCACCT TCACCCACAA GATCAACCTC 
CCCAAAAAAG CCTGCCCATG TGCAAGCTCT GCCCAGGTAC TGCAGGAACT GTTGAGCCGA 
ATCGAGATGC TGGAGAGGGA GGTGTCAGTG CTGCGAGACC AGTGCAACAC CAACTGCTGT 
CAGGAAAGTG CTGCCACAGG ACAACTGGAC TATGTCCCTC ACTGCAGCGG CCATGGCAAC 
TTTAGCTTCG AGTCCTGTGG CTGCATCTGC AATGAAGGCT GGTTTGGCAA GAACTGCTCA 
GAGCCCTACT GCCCATTGGG CTGCTCCAGT CGGGGTGTAT GTGTCGATGG CCAGTGCATT 
TGTGACAGTG AATACAGCGG AGATGACTGT TCAGAGCTCC GGTGCCCAAC AGACTGCAGT 
TCCCGAGGGC TCTGTGTGGA TGGGGAATGT GTCTGTGAAG AGCCCTACAC AGGCGAGGAC 
TGCAGGGAGC TGCGTTGCCC TGGGGACTGT TCAGGGAAGG GGCAATGTGC CAATGGTACC 
TGCCTGTGCC AAGAGGGCTA TGCTGGTGAG GACTGCAGTC AGCGACGGTG TCTGAATGCT 
TGCAGTGGGC GAGGTCACTG CCAGGAGGGG CTCTGCATCT GTGAGGAGGG CTACCAGGGC 
CCTGACTGCT CAGCAGTTAC CCCTCCAGAG GACTTGCGAG TGGCTGGTAT CAGCGACAGG 
TCCATTGAGC TGGAATGGGA CGGGCCGATG GCAGTGACGG AATATGTGAT CTCTTACCAG 
CCGAGCCTGG GGGGCCTTCA GCTCCAGCAG CGGGTGCCTG GAGATTGGAG TGGTGTCACC 
ATCACGGAGC TGGAGCCAGG TCTCACCTAC AACATCAGCG TCTACGCTGT CATTAGCAAC 
ATCCTCAGCC TTCCCATCAC TGCCAAGGTG GCCACTCATC TTTCTACTCC TCAAGGGCTA 
CAGTTCAAGA CGATCACAGA GACCACCGTG GAAGTGCAGT GGGAGCCCTT CTCTTTCTCC 
TTCGATGGGT GGGAGATCAG CTTCACTCCA AAGAACAATG AAGGAGGGGT GATAGCTCAG 
CTCCCCAGCG ATGTTACGTC CTTTAACCAA ACGGGACTGA AACCTGGGGA GGAGTACATT 
GTGAATGTTG TAGCACTAAA GGAACAAGCC CGGGGCCCTC CGACCTCTGC CAGCGTCTCC 
ACTGTCATTG ACGGGCCCAC ACAGATCCTG GTTCGAGATG TCTCTGATAC TGTGGCCTTT 
GTGGAATGGA CCCCACCTCG AGCCAAAGTT GATTTCATTC TATTAAAATA TGGCTTGGTG 
GGTGGCGAAG GTGGGAAGAC TACCTTCCGG CTGCAGCCTC CCCTTAGCCA GTACTCAGTG 
CAAGCCCTTA GACCTGGCTC CCGCTACGAG GTGTCCATCA GCGCAGTCCG GGGGACCAAT 
GAAAGTGATG CCTCAAGCAC CCAGTTTACA ACAGAAATTG ATGCTCCCAA GAATTTGCGA 
GTGGGTTCCC GGACAGCAAC TAGCCTTGAC CTCGAATGGG ATAACAGCGA GGCTGAAGCT 
CAGGAGTACA AGGTTGTGTA CAGCACCCTA GCCGGGGAGC AGTACCATGA AGTGCTGGTA 
CCCAAAGGCA TTGGTCCAAC TACCAAGACT ACCCTCACAG ATCTGGTTCC AGGCACAGAA 
TATGGAGTTG GAATATCTGC GGTAATGAAC TCGAAACAAA GCATTCCCGC TACCATGAAT 
GCCAGGACTG AGCTTGACAG TCCCCGAGAC CTCATGGTAA CAGCTTCCTC AGAGACCTCT 
ATCTCTCTCA TCTGGACGAA GGCCAGTGGT CCTATTGATC ACTATCGAAT TACTTTTACT 
CCATCTTCTG GGATCTCCTC AGAAGTCACT GTGCCTAGGG ATAGGACTTC ATATACACTG 
ACAGATCTAG AGCCTGGAGC AGAATACATC ATCTCCATTA CTGCTGAGAG GGGTCGGCAG 
CAGAGCCTGG AGTCTACTGT GGATGCCTTC ACAGGCTTCC GCCCTATCTC CCACTTGCAC 
TTTTCTCATG TGACCTCCTC CAGTGTCAAC ATCACCTGGA GTGACCCATC TCCCCCAGCA 
GACAGACTCA TTCTGAACTA CAGCCCCAGG GATGAAGAGG AGGAGATGAT GGAGGTTCTC 
TTGGATGCCA CCAAGAGGCA CGCCGTCCTA ATGGGTCTAC AGCCAGCCAC TGAATATATA 
GTGAATCTCG TAGCTGTCCA TGGGACAGTA ACCTCTGAAC CCATAGTGGG TTCTATCACT 
ACAGGAATTG ATCCTCCCAA AAACATCACA ATTAGCAACG TGACTAAGGA CTCCCTGACA 
GTTTCCTGGA GCCCTCCTGT TGCGCCTTTT GATTACTACG AGTATCCTAT CGACCACCCA 
AGTGGACGGC TGGACAGCTC TGTCGTGCCC AACACTGTGA CAGAGTTCAC AATCACCAGG 
CTCTATCCAG CTAGTCAATA TGAAATAAGC CTCAACAGTG TACGCGGGAG GGAGGAGAGT 
GAACGCATCT GCACCCTGGT GCACACAGCC ATGGATAGCC CCATGGATCT AATTGCTACC 
AACATCACGC CAACAGAAGC CCTGCTCCAG TGGAAGGCAC CCATGGGTGA AGTGGAAAAT 
TATGTCATTG TCCTCACCCA CTTTGCCATG GCTGGAGAGA CCATCCTGGT TGATGGGGTC 
AGTGAAGAAT TCCAGCTTGT AGACCTGCTT CCTAGGACCC ACTACACTGT CACCATGTAT 
GCTACCAGTG GACCTCTCGT GAGTGGCACC ATCGCCACCA ACTTCTCCAC CCTCCTGGAC 
CCTCCCGCCA ACCTGACAGC CAGTGAAGTC ACCAGGCAAA GCGCACTGAT CTCCTGGCAG 
CCACCCAGAG CTGCGATTGA AAACTATGTC TTGACATACA AGTCCACCGA TGGAAGCCGC 
AAGGAGCTGA TTGTGGATGC TGAGGACACC TGGATCCGAC TGGAGGGCCT GTCGGAGAAC 
ACAGACTACA CAGTGCTCCT GCAGGCAGCT CAGGAGGCCA CAAGGAGCAG CCTCACCTCT 
ACTATCTTTA CCACAGGGGG CCGGGTGTTC TCTCATCCTC AAGACTGTGC CCAGCACTTG 
ATGAATGGAG ACACTCTGAG TGGAGTTTAC ACCATCTTCC TCAATGGGGA GTTAAGCCAC 
AAGTTGCAAG TATACTGCGA TATGACCACA GATGGGGGCG GCTGGATTGT TTTCCAGAGA 
CGGCAAAATG GCCAAACTGA TTTTTTCCGG AAATGGGCAG ATTACCGTGT TGGCTTTGGG 
AATCTGGAGG ATGAGTTTTG GCTAGGGCTA GACAACTACC ACAGGATAAC AGCCCAGGGC 
CGCTATGAGC TGCGTGTGGA TATGCGGGAT GGACAGGAGG CCGTCTTTGC CTACTATGAC 
AAGTTCGCTG TGGAGGACAG CAGAAGCCTG TACAAGCTCC GTATAGGAGG CTACAATGGC 
ACTGCAGGAG ACTCCCTTAG CTATCACCAG GGACGTCCTT TCTCCACTGA GGACAGAGAC 
AATGATGTTG CAGTCACCAA CTGTGCCATG TCATACAAGG GTGCTTGGTG GTATAAGAAC 
TGCCACCGGA CCAACCTCAA CGGGAAGTAT GGGGAGTCCA GGCACAGTCA GGGGATCAAC 
TGGTACCATT GGAAAGGCCA TGAATTCTCC ATCCCCTTTG TAGAAATGAA GATGAGGCCC 
TACATCCATC GTCTCACAGC CGGGAGGAAA CGGCGAGCCT TGAAATTCTG A