Casp3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Casp3
Entrez Gene ID	25402
Full Name	caspase 3
Synonyms	CPP32-beta,Lice,Yama
General protein information	Preferred Names caspase 3 Names caspase-3 CASP-3 CPP-32 CPP32beta Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease) IRP SCA-1 SREBP cleavage activity 1 apopain cysteine protease CPP32 cysteine protease p32-beta protein Yama yama protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16q11
Summary	apoptotic cysteine-aspartic acid protease that may play a role in neuronal cell death regulation and other apoptotic processes [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006253130.3	XP_006253192.1	caspase-3 isoform X1
NM_012922.2	NP_037054.1	caspase-3

Pathways from BioSystems

Homologies

Homo sapiens (human)	CASP3	NP_004337.2
Canis lupus familiaris (dog)	CASP3	NP_001003042.1
Rattus norvegicus (Norway rat)	Casp3	NP_037054.1
Gallus gallus (chicken)	CASP3	NP_990056.1
	CASP3	XP_001083044.1
Anopheles gambiae (African malaria mosquito)	CASPS8	XP_318945.3
Xenopus tropicalis (tropical clawed frog)	casp3	NP_001120900.1
Pan troglodytes (chimpanzee)	CASP3	NP_001012435.1
Bos taurus (cattle)	CASP3	NP_001071308.1
Mus musculus (house mouse)	Casp3	NP_001271338.1

Gene Ontology

The following Casp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Casp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13459	NM_012922.2 Latest version!	Rattus norvegicus caspase 3 (Casp3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa13459	XM_006253130.3 Latest version!	Rattus norvegicus caspase 3 (Casp3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Casp3 ( NM_012922.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037054.1 Rattus norvegicus caspase 3 (Casp3), mRNA.

Price & Availability↑

CloneID	ORa13459
Clone ID Related Accession (Same CDS sequence)	XM_006253130.3 , NM_012922.2
Accession Version	NM_012922.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Rattus norvegicus(Norway rat)
Product	caspase-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081854.1. On Sep 16, 2004 this sequence version replaced NM_012922.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC081854.1, CK357386.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906351 [ECO:0000348] ##Evidence-Data-END##

ATGGACAACA ACGAAACCTC CGTGGATTCA AAATCCATTA ATAATTTTGA AACAAAGACT 
ATCCATGGAA GCAAGTCGAT GGACTCTGGA ATATATCTGG ACAGCAGTTA CAAAATGGAT 
TACCCTGAAA TGGGCTTGTG TATAATAATT AATAATAAGA ACTTCCATAA AAGCACTGGA 
ATGTCAGCTC GCAATGGTAC CGATGTCGAT GCAGCTAACC TCAGAGAGAC ATTCATGGCC 
CTGAAATACG AAGTCAGGAA TAAAAATGAC CTTACTCGTG AAGAAATTAT GGAATTGATG 
GATAGTGTTT CTAAGGAAGA TCACAGCAAA AGGAGCAGTT TTGTGTGTGT GATTCTAAGT 
CATGGAGATG AAGGAGTAAT TTTTGGAACG AACGGACCTG TGGACCTGAA AAAACTAACT 
AGTTTCTTCA GAGGCGACTA CTGCCGGAGT CTGACTGGAA AGCCGAAACT CTTCATCATT 
CAGGCCTGCC GAGGTACAGA GCTGGACTGC GGTATTGAGA CAGACAGTGG AACTGACGAT 
GATATGGCAT GCCAGAAGAT ACCAGTGGAG GCCGACTTCC TGTATGCTTA CTCTACCGCA 
CCCGGTTACT ATTCCTGGAG AAATTCAAGG GACGGGTCAT GGTTCATCCA GTCACTTTGC 
GCCATGCTGA AACTGTACGC GCACAAGCTG GAATTCATGC ACATCCTCAC TCGTGTTAAC 
CGGAAGGTGG CCACGGAATT TGAGTCCTTC TCCCTGGACG CCACTTTCCA TGCAAAGAAA 
CAGATCCCGT GTATTGTGTC AATGCTCACA AAAGAACTGT ACTTTTATCA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037054.1
CDS	57..890
Translation	MDNNETSVDSKSINNFETKTIHGSKSMDSGIYLDSSYKMDYPEMGLCIIINNKNFHKSTGMSARNGTDVDAANLRETFMALKYEVRNKNDLTREEIMELMDSVSKEDHSKRSSFVCVILSHGDEGVIFGTNGPVDLKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDDDMACQKIPVEADFLYAYSTAPGYYSWRNSRDGSWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFESFSLDATFHAKKQIPCIVSMLTKELYFYH

Target ORF information:

RefSeq Version	NM_012922.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus caspase 3 (Casp3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012922.2

ORF Insert Sequence:

ATGGACAACA ACGAAACCTC CGTGGATTCA AAATCCATTA ATAATTTTGA AACAAAGACT 
ATCCATGGAA GCAAGTCGAT GGACTCTGGA ATATATCTGG ACAGCAGTTA CAAAATGGAT 
TACCCTGAAA TGGGCTTGTG TATAATAATT AATAATAAGA ACTTCCATAA AAGCACTGGA 
ATGTCAGCTC GCAATGGTAC CGATGTCGAT GCAGCTAACC TCAGAGAGAC ATTCATGGCC 
CTGAAATACG AAGTCAGGAA TAAAAATGAC CTTACTCGTG AAGAAATTAT GGAATTGATG 
GATAGTGTTT CTAAGGAAGA TCACAGCAAA AGGAGCAGTT TTGTGTGTGT GATTCTAAGT 
CATGGAGATG AAGGAGTAAT TTTTGGAACG AACGGACCTG TGGACCTGAA AAAACTAACT 
AGTTTCTTCA GAGGCGACTA CTGCCGGAGT CTGACTGGAA AGCCGAAACT CTTCATCATT 
CAGGCCTGCC GAGGTACAGA GCTGGACTGC GGTATTGAGA CAGACAGTGG AACTGACGAT 
GATATGGCAT GCCAGAAGAT ACCAGTGGAG GCCGACTTCC TGTATGCTTA CTCTACCGCA 
CCCGGTTACT ATTCCTGGAG AAATTCAAGG GACGGGTCAT GGTTCATCCA GTCACTTTGC 
GCCATGCTGA AACTGTACGC GCACAAGCTG GAATTCATGC ACATCCTCAC TCGTGTTAAC 
CGGAAGGTGG CCACGGAATT TGAGTCCTTC TCCCTGGACG CCACTTTCCA TGCAAAGAAA 
CAGATCCCGT GTATTGTGTC AATGCTCACA AAAGAACTGT ACTTTTATCA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Casp3 ( XM_006253130.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006253192.1 Rattus norvegicus caspase 3 (Casp3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa13459
Clone ID Related Accession (Same CDS sequence)	XM_006253130.3 , NM_012922.2
Accession Version	XM_006253130.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	caspase-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005115.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006253130.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACAACA ACGAAACCTC CGTGGATTCA AAATCCATTA ATAATTTTGA AACAAAGACT 
ATCCATGGAA GCAAGTCGAT GGACTCTGGA ATATATCTGG ACAGCAGTTA CAAAATGGAT 
TACCCTGAAA TGGGCTTGTG TATAATAATT AATAATAAGA ACTTCCATAA AAGCACTGGA 
ATGTCAGCTC GCAATGGTAC CGATGTCGAT GCAGCTAACC TCAGAGAGAC ATTCATGGCC 
CTGAAATACG AAGTCAGGAA TAAAAATGAC CTTACTCGTG AAGAAATTAT GGAATTGATG 
GATAGTGTTT CTAAGGAAGA TCACAGCAAA AGGAGCAGTT TTGTGTGTGT GATTCTAAGT 
CATGGAGATG AAGGAGTAAT TTTTGGAACG AACGGACCTG TGGACCTGAA AAAACTAACT 
AGTTTCTTCA GAGGCGACTA CTGCCGGAGT CTGACTGGAA AGCCGAAACT CTTCATCATT 
CAGGCCTGCC GAGGTACAGA GCTGGACTGC GGTATTGAGA CAGACAGTGG AACTGACGAT 
GATATGGCAT GCCAGAAGAT ACCAGTGGAG GCCGACTTCC TGTATGCTTA CTCTACCGCA 
CCCGGTTACT ATTCCTGGAG AAATTCAAGG GACGGGTCAT GGTTCATCCA GTCACTTTGC 
GCCATGCTGA AACTGTACGC GCACAAGCTG GAATTCATGC ACATCCTCAC TCGTGTTAAC 
CGGAAGGTGG CCACGGAATT TGAGTCCTTC TCCCTGGACG CCACTTTCCA TGCAAAGAAA 
CAGATCCCGT GTATTGTGTC AATGCTCACA AAAGAACTGT ACTTTTATCA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006253192.1
CDS	107..940
Translation	MDNNETSVDSKSINNFETKTIHGSKSMDSGIYLDSSYKMDYPEMGLCIIINNKNFHKSTGMSARNGTDVDAANLRETFMALKYEVRNKNDLTREEIMELMDSVSKEDHSKRSSFVCVILSHGDEGVIFGTNGPVDLKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDDDMACQKIPVEADFLYAYSTAPGYYSWRNSRDGSWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFESFSLDATFHAKKQIPCIVSMLTKELYFYH

Target ORF information:

RefSeq Version	XM_006253130.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus caspase 3 (Casp3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006253130.3

ORF Insert Sequence:

ATGGACAACA ACGAAACCTC CGTGGATTCA AAATCCATTA ATAATTTTGA AACAAAGACT 
ATCCATGGAA GCAAGTCGAT GGACTCTGGA ATATATCTGG ACAGCAGTTA CAAAATGGAT 
TACCCTGAAA TGGGCTTGTG TATAATAATT AATAATAAGA ACTTCCATAA AAGCACTGGA 
ATGTCAGCTC GCAATGGTAC CGATGTCGAT GCAGCTAACC TCAGAGAGAC ATTCATGGCC 
CTGAAATACG AAGTCAGGAA TAAAAATGAC CTTACTCGTG AAGAAATTAT GGAATTGATG 
GATAGTGTTT CTAAGGAAGA TCACAGCAAA AGGAGCAGTT TTGTGTGTGT GATTCTAAGT 
CATGGAGATG AAGGAGTAAT TTTTGGAACG AACGGACCTG TGGACCTGAA AAAACTAACT 
AGTTTCTTCA GAGGCGACTA CTGCCGGAGT CTGACTGGAA AGCCGAAACT CTTCATCATT 
CAGGCCTGCC GAGGTACAGA GCTGGACTGC GGTATTGAGA CAGACAGTGG AACTGACGAT 
GATATGGCAT GCCAGAAGAT ACCAGTGGAG GCCGACTTCC TGTATGCTTA CTCTACCGCA 
CCCGGTTACT ATTCCTGGAG AAATTCAAGG GACGGGTCAT GGTTCATCCA GTCACTTTGC 
GCCATGCTGA AACTGTACGC GCACAAGCTG GAATTCATGC ACATCCTCAC TCGTGTTAAC 
CGGAAGGTGG CCACGGAATT TGAGTCCTTC TCCCTGGACG CCACTTTCCA TGCAAAGAAA 
CAGATCCCGT GTATTGTGTC AATGCTCACA AAAGAACTGT ACTTTTATCA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.