Drgx cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Drgx
Entrez Gene ID	252880
Full Name	dorsal root ganglia homeobox
Synonyms	Drg11,Prrxl1
General protein information	Preferred Names dorsal root ganglia homeobox Names dorsal root ganglia homeobox protein dorsal root ganglion 11 homeobox protein DRG11 paired-like homeodomain trancription factor Drg11 paired-related homeobox protein-like 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 16 Map Location: 16p16
Summary	paired homeodomain protein; may be involved in regulating sensory neuron synapse formation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_145767.1	NP_665710.1	dorsal root ganglia homeobox protein

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	DRGX	XP_001234656.2
Danio rerio (zebrafish)	drgx	NP_001032182.1
Xenopus tropicalis (tropical clawed frog)	drgx	XP_002939787.1
Homo sapiens (human)	DRGX	NP_001263380.1
Pan troglodytes (chimpanzee)	DRGX	XP_001138723.1
Rattus norvegicus (Norway rat)	Drgx	NP_665710.1
	DRGX	XP_001113450.2
Canis lupus familiaris (dog)	DRGX	XP_005637539.1
Bos taurus (cattle)	DRGX	XP_002699015.1

Gene Ontology
Bibliography

Related articles in PubMed

Involvement of DRG11 in the development of the primary afferent nociceptive system.
Rebelo S, Chen ZF, Anderson DJ, Lima D
Molecular and cellular neurosciences33(3)236-46(2006 Nov)

Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.
Ding YQ, Yin J, Kania A, Zhao ZQ, Johnson RL, Chen ZF
Development (Cambridge, England)131(15)3693-703(2004 Aug)

DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.
Samad TA, Srinivasan A, Karchewski LA, Jeong SJ, Campagna JA, Ji RR, Fabrizio DA, Zhang Y, Lin HY, Bell E, Woolf CJ
The Journal of neuroscience : the official journal of the Society for Neuroscience24(8)2027-36(2004 Feb)

Formation of whisker-related principal sensory nucleus-based lemniscal pathway requires a paired homeodomain transcription factor, Drg11.
Ding YQ, Yin J, Xu HM, Jacquin MF, Chen ZF
The Journal of neuroscience : the official journal of the Society for Neuroscience23(19)7246-54(2003 Aug)

The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord.
Chen ZF, Rebelo S, White F, Malmberg AB, Baba H, Lima D, Woolf CJ, Basbaum AI, Anderson DJ
Neuron31(1)59-73(2001 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Drgx gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Drgx cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02648	NM_145767.1 Latest version!	Rattus norvegicus dorsal root ganglia homeobox (Drgx), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Drgx ( NM_145767.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_665710.1 Rattus norvegicus dorsal root ganglia homeobox (Drgx), mRNA.

Price & Availability↑

CloneID	ORa02648
Clone ID Related Accession (Same CDS sequence)	NM_145767.1
Accession Version	NM_145767.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	dorsal root ganglia homeobox protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U29174.1. ##Evidence-Data-START## Transcript exon combination :: U29174.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMN04563757 [ECO:0000348] ##Evidence-Data-END##

ATGTTTTATT TCCACTGCCC GCCACAGCTA GAGGGCACAG CGCCTTTTGG TAACCACTCT 
ACGGGGGATT TTGATGATGG GTTTCTTAGA AGAAAACAGC GCAGAAATCG GACAACCTTC 
GCTCTTCAGC AGTTGGAAGC TCTGGAGGCA GTCTTTGCCC AAACACACTA CCCAGATGTC 
TTCACCAGAG AAGAGCTAGC CATGAAAATA AACCTCACAG AAGCCAGAGT GCAGGTTTGG 
TTCCAGAACC GAAGAGCCAA GTGGAGGAAG ACAGAGAGAG GGGCCTCTGA CCAGGAACCA 
GGGGCTAAGG AACCCATGGC AGAGGTGACA CCACCCCCAG TGAGGAACAT CAACTCTCCA 
CCCCCAGGGG ACCAGGCCCG GGGCAAGAAG GAGGCCCTGG AGGCCCAGCA GAGCCTGGGA 
CGCACAGTGG GCCCCGCCGG GCCTTTCTTC CCCTCCTGCT TGCCAGGGAC CCTCCTGAAC 
ACAGCCACTT ATGCCCAGGC CCTGTCCCAT GTGGCATCTC TGAAAGGGGG CCCACTGTGC 
TCTTGCTGCG TCCCAGACCC TATGGGGCTC TCCTTCCTCC CCACTTACGG TTGCCAGAGT 
AACCGCACAG CCAGCGTGGC TGCCCTGCGC ATGAAGGCCC GCGAGCATTC AGAAGCGGTC 
CTGCAGTCTG CCAACCTTCT GCCGTCCACC AGCAGCAGCC CCGGCCCTGC CTCCAAGCAG 
GTGCCTCCAG AAGGCAGCCA GGACAAGCCC TCCCCAACGA AGGAACAGAG CGAGGGAGAG 
AAGAGCGTAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_665710.1
CDS	279..1070
Translation	MFYFHCPPQLEGTAPFGNHSTGDFDDGFLRRKQRRNRTTFALQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQARGKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPSTSSSPGPASKQVPPEGSQDKPSPTKEQSEGEKSV

Target ORF information:

RefSeq Version	NM_145767.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dorsal root ganglia homeobox (Drgx), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145767.1

ORF Insert Sequence:

ATGTTTTATT TCCACTGCCC GCCACAGCTA GAGGGCACAG CGCCTTTTGG TAACCACTCT 
ACGGGGGATT TTGATGATGG GTTTCTTAGA AGAAAACAGC GCAGAAATCG GACAACCTTC 
GCTCTTCAGC AGTTGGAAGC TCTGGAGGCA GTCTTTGCCC AAACACACTA CCCAGATGTC 
TTCACCAGAG AAGAGCTAGC CATGAAAATA AACCTCACAG AAGCCAGAGT GCAGGTTTGG 
TTCCAGAACC GAAGAGCCAA GTGGAGGAAG ACAGAGAGAG GGGCCTCTGA CCAGGAACCA 
GGGGCTAAGG AACCCATGGC AGAGGTGACA CCACCCCCAG TGAGGAACAT CAACTCTCCA 
CCCCCAGGGG ACCAGGCCCG GGGCAAGAAG GAGGCCCTGG AGGCCCAGCA GAGCCTGGGA 
CGCACAGTGG GCCCCGCCGG GCCTTTCTTC CCCTCCTGCT TGCCAGGGAC CCTCCTGAAC 
ACAGCCACTT ATGCCCAGGC CCTGTCCCAT GTGGCATCTC TGAAAGGGGG CCCACTGTGC 
TCTTGCTGCG TCCCAGACCC TATGGGGCTC TCCTTCCTCC CCACTTACGG TTGCCAGAGT 
AACCGCACAG CCAGCGTGGC TGCCCTGCGC ATGAAGGCCC GCGAGCATTC AGAAGCGGTC 
CTGCAGTCTG CCAACCTTCT GCCGTCCACC AGCAGCAGCC CCGGCCCTGC CTCCAAGCAG 
GTGCCTCCAG AAGGCAGCCA GGACAAGCCC TCCCCAACGA AGGAACAGAG CGAGGGAGAG 
AAGAGCGTAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Involvement of DRG11 in the development of the primary afferent nociceptive system.
Molecular and cellular neurosciences33(3)236-46(2006 Nov)
Rebelo S,Chen ZF,Anderson DJ,Lima D

Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.
Development (Cambridge, England)131(15)3693-703(2004 Aug)
Ding YQ,Yin J,Kania A,Zhao ZQ,Johnson RL,Chen ZF

DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.
The Journal of neuroscience : the official journal of the Society for Neuroscience24(8)2027-36(2004 Feb)
Samad TA,Srinivasan A,Karchewski LA,Jeong SJ,Campagna JA,Ji RR,Fabrizio DA,Zhang Y,Lin HY,Bell E,Woolf CJ

Formation of whisker-related principal sensory nucleus-based lemniscal pathway requires a paired homeodomain transcription factor, Drg11.
The Journal of neuroscience : the official journal of the Society for Neuroscience23(19)7246-54(2003 Aug)
Ding YQ,Yin J,Xu HM,Jacquin MF,Chen ZF

The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord.
Neuron31(1)59-73(2001 Jul)
Chen ZF,Rebelo S,White F,Malmberg AB,Baba H,Lima D,Woolf CJ,Basbaum AI,Anderson DJ