Cd99l2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd99l2
Entrez Gene ID	171485
Full Name	CD99 molecule-like 2
Synonyms	Mic2l1,vms-tm2
General protein information	Preferred Names CD99 molecule-like 2 Names CD99 antigen-like protein 2 CD99 antigen-like protein 2-like Cd99 antigen-like 2 MIC2 like 1 MIC2-like protein 1 Rhombex-40 protein rhombex-40 rhombencephalic expression protein 40 kDa single-pass transmembrane protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p16
Summary	enriched in respiration-related neurons; may play a role in detection of chemicals in cerebrospinal fluid [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_134459.1	NP_604454.1	CD99 antigen-like protein 2 precursor
XM_006251676.3	XP_006251738.1	CD99 antigen-like protein 2 isoform X1
XM_017588459.1	XP_017443948.1	CD99 antigen-like protein 2 isoform X2

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Cutting edge: Endothelial-specific gene ablation of CD99L2 impairs leukocyte extravasation in vivo.
Seelige R, Natsch C, M?rz S, Jing D, Frye M, Butz S, Vestweber D
Journal of immunology (Baltimore, Md. : 1950)190(3)892-6(2013 Feb)

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM
Nature cell biology13(4)383-93(2011 Apr)

A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo.
Bixel MG, Petri B, Khandoga AG, Khandoga A, Wolburg-Buchholz K, Wolburg H, M?rz S, Krombach F, Vestweber D
Blood109(12)5327-36(2007 Jun)

Cloning, genomic organization, alternative transcripts and expression analysis of CD99L2, a novel paralog of human CD99, and identification of evolutionary conserved motifs.
Suh YH, Shin YK, Kook MC, Oh KI, Park WS, Kim SH, Lee IS, Park HJ, Huh TL, Park SH
Gene30763-76(2003 Mar)

Molecular cloning of Rhombex-40 a transmembrane protein from the ventral medullary surface of the rat brain by differential display.
Shimokawa N, Jingu H, Okada J, Miura M
Life sciences66(22)2183-91(2000 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cd99l2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd99l2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa42443	NM_134459.1 Latest version!	Rattus norvegicus CD99 molecule-like 2 (Cd99l2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa21871	XM_006251676.3 Latest version!	Rattus norvegicus CD99 molecule-like 2 (Cd99l2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd99l2 ( NM_134459.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_604454.1 Rattus norvegicus CD99 molecule-like 2 (Cd99l2), mRNA.

Price & Availability↑

CloneID	ORa42443
Clone ID Related Accession (Same CDS sequence)	NM_134459.1
Accession Version	NM_134459.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	CD99 antigen-like protein 2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB031014.1. On Jan 12, 2005 this sequence version replaced XM_346473.1. ##Evidence-Data-START## Transcript exon combination :: AB031014.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGTGGCTA GGCTCACCAC TCTCCTCGTT TGCCTCGTTT TCTCCTTGGC TACCCTGGTC 
CAGAGAGGAT ATGGAGACTT CGATGATTTC AATCTGGAGG ATGCGCTGAA AGAAACTTCC 
TCAGTAAAGC AGAGCCACTT TAGTACGACG ACTAGGAGGA CAGGAACGAC CAGAGCCCCA 
GCGAATCCAG CAGAGAGATG GGACCACATG ACCACTACTA CAACGAAAAG GCCAGGAACA 
ACTAGAGCAC CGTCAAATCC TCTGGAACTT GATGGGTTTG ACTTGGAAGA CGCCTTGGAT 
GATCGGAATG ATCTAGATGG CCCCAAAAAG CCAAGTACAG GAGAAGGAGG AGGTTTGTCA 
GACAAGGATC TCGAAGACAT CTTGGGAGGC GGAGGATACA AACCTGACAA GAATAAAGGT 
GGCGGTGGTG GTTATGGCAG CCAGGATGAC CCTGGATCAG GAGCAGTGAC GGACCCCGGC 
ACCATTGCGG GCCTGGTCAG CGCCCTGGCC GCGGCCCTCC TCGGAGCGGT GTCCGGCTAC 
CTCTCCTACC AGCATCGGAA GTTCTGTTTC AGTGTCCAGC GCGGCCTCGA CGCAGCCTAC 
GTGAAGGGGG AAACCTTGAA GCTGTTGTGT GTCGAAGAGC CCCGGGTGGA AGCCGCGATG 
TGCGAGGCGC CCCAGTTACG GACTCCACAC AACACTCGCA GCCCACAGAG CCCCTGGCAC 
CAGAGCGGCC CCGGATCTGA GGCCCGGGAT CTTAGGCCTC GCTCAATGGT CAGCGCTTTG 
CACCCTGATG TCCTCCGTTC ATCCTTTCCC CGGGTTCCTT CCCCATCCCC AGCTTCTCCC 
CACACCTGGT TTTCCGCACC AGCCTTGGGG GTGTGTGAGT TGCGGTTTCT GCGCCCTTCC 
GTGCGGACCG CGCTGACCAC TGTGCGGCGC GGCCTCCGGA GAGACTCGGA GCCGAGCCCT 
GCGATCCCCG TTCAGCCGAG TGCGGTGCGC ACATTTGTGG TTTTTGCGCT GACCACTAAG 
CGCTGTGAGG AGTGCGCCCA GCTGGCACTT GGTGCATTCG GAACACACTT GAGACAAATC 
AGACAGCTGC AACGCACACG CGCACACACA CACACACACA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_604454.1
CDS	64..1188
Translation	MVARLTTLLVCLVFSLATLVQRGYGDFDDFNLEDALKETSSVKQSHFSTTTRRTGTTRAPANPAERWDHMTTTTTKRPGTTRAPSNPLELDGFDLEDALDDRNDLDGPKKPSTGEGGGLSDKDLEDILGGGGYKPDKNKGGGGGYGSQDDPGSGAVTDPGTIAGLVSALAAALLGAVSGYLSYQHRKFCFSVQRGLDAAYVKGETLKLLCVEEPRVEAAMCEAPQLRTPHNTRSPQSPWHQSGPGSEARDLRPRSMVSALHPDVLRSSFPRVPSPSPASPHTWFSAPALGVCELRFLRPSVRTALTTVRRGLRRDSEPSPAIPVQPSAVRTFVVFALTTKRCEECAQLALGAFGTHLRQIRQLQRTRAHTHTHM

Target ORF information:

RefSeq Version	NM_134459.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD99 molecule-like 2 (Cd99l2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134459.1

ORF Insert Sequence:

ATGGTGGCTA GGCTCACCAC TCTCCTCGTT TGCCTCGTTT TCTCCTTGGC TACCCTGGTC 
CAGAGAGGAT ATGGAGACTT CGATGATTTC AATCTGGAGG ATGCGCTGAA AGAAACTTCC 
TCAGTAAAGC AGAGCCACTT TAGTACGACG ACTAGGAGGA CAGGAACGAC CAGAGCCCCA 
GCGAATCCAG CAGAGAGATG GGACCACATG ACCACTACTA CAACGAAAAG GCCAGGAACA 
ACTAGAGCAC CGTCAAATCC TCTGGAACTT GATGGGTTTG ACTTGGAAGA CGCCTTGGAT 
GATCGGAATG ATCTAGATGG CCCCAAAAAG CCAAGTACAG GAGAAGGAGG AGGTTTGTCA 
GACAAGGATC TCGAAGACAT CTTGGGAGGC GGAGGATACA AACCTGACAA GAATAAAGGT 
GGCGGTGGTG GTTATGGCAG CCAGGATGAC CCTGGATCAG GAGCAGTGAC GGACCCCGGC 
ACCATTGCGG GCCTGGTCAG CGCCCTGGCC GCGGCCCTCC TCGGAGCGGT GTCCGGCTAC 
CTCTCCTACC AGCATCGGAA GTTCTGTTTC AGTGTCCAGC GCGGCCTCGA CGCAGCCTAC 
GTGAAGGGGG AAACCTTGAA GCTGTTGTGT GTCGAAGAGC CCCGGGTGGA AGCCGCGATG 
TGCGAGGCGC CCCAGTTACG GACTCCACAC AACACTCGCA GCCCACAGAG CCCCTGGCAC 
CAGAGCGGCC CCGGATCTGA GGCCCGGGAT CTTAGGCCTC GCTCAATGGT CAGCGCTTTG 
CACCCTGATG TCCTCCGTTC ATCCTTTCCC CGGGTTCCTT CCCCATCCCC AGCTTCTCCC 
CACACCTGGT TTTCCGCACC AGCCTTGGGG GTGTGTGAGT TGCGGTTTCT GCGCCCTTCC 
GTGCGGACCG CGCTGACCAC TGTGCGGCGC GGCCTCCGGA GAGACTCGGA GCCGAGCCCT 
GCGATCCCCG TTCAGCCGAG TGCGGTGCGC ACATTTGTGG TTTTTGCGCT GACCACTAAG 
CGCTGTGAGG AGTGCGCCCA GCTGGCACTT GGTGCATTCG GAACACACTT GAGACAAATC 
AGACAGCTGC AACGCACACG CGCACACACA CACACACACA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd99l2 ( XM_006251676.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006251738.1 Rattus norvegicus CD99 molecule-like 2 (Cd99l2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa21871
Clone ID Related Accession (Same CDS sequence)	XM_006251676.3
Accession Version	XM_006251676.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	CD99 antigen-like protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251676.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGCTA GGCTCACCAC TCTCCTCGTT TGCCTCGTTT TCTCCTTGGC TACCCTGGTC 
CAGAGAGGAT ATGGAGACTT CGATGATTTC AATCTGGAGG ATGCGCTTAA AGAAACTTCC 
TCAGTAAAGC AGAGCCACTT TAGTACGACG ACTAGGAGGA CAGGAACGAC CAGAGCCCCA 
GCGAATCCAG CAGAGAGATG GGACCACATG ACCACTACTA CAACGAAAAG GCCAGGAACA 
ACTAGAGCAC CGTCAAATCC TCTGGAACTT GATGGGTTTG ACTTGGAAGA CGCCTTGGAT 
GATCGGAATG ATCTAGATGG CCCCAAAAAG CCAAGTACAG GAGAAGGAGG AGGTTTGTCA 
GACAAGGATC TCGAAGACAT CTTGGGAGGC GGGGGATACA AACCTGACAA GAATAAAGGT 
GGCGGTGGTG GTTATGGCAG CCAGGATGAC CCTGGATCAG GAGCAGTGAC GGACCCCGGC 
ACCATTGCGG GCCTGGTCAG CGCCCTGGCC GCGGCCCTCC TCGGAGCGGT GTCCGGCTAC 
CTCTCCTACC AGCATCGGAA GTTCTGTTTC AGTGTCCAGC GCGGCCTCGA CGCAGCCTAC 
GTGAAGGGGG AAAACCTGGA AGCTGTGGTG TGCGAGGAGC CCCGGGTGGA AGCCGCGATG 
TGCGAGGCGC CCCCAGTGAC GGACTCCACA CAACACTCGC AGCCCACAGA GCCCCTGGCA 
CCAGAGCGGC CCCGGATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006251738.1
CDS	139..879
Translation	MVARLTTLLVCLVFSLATLVQRGYGDFDDFNLEDALKETSSVKQSHFSTTTRRTGTTRAPANPAERWDHMTTTTTKRPGTTRAPSNPLELDGFDLEDALDDRNDLDGPKKPSTGEGGGLSDKDLEDILGGGGYKPDKNKGGGGGYGSQDDPGSGAVTDPGTIAGLVSALAAALLGAVSGYLSYQHRKFCFSVQRGLDAAYVKGENLEAVVCEEPRVEAAMCEAPPVTDSTQHSQPTEPLAPERPRI

Target ORF information:

RefSeq Version	XM_006251676.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus CD99 molecule-like 2 (Cd99l2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006251676.3

ORF Insert Sequence:

ATGGTGGCTA GGCTCACCAC TCTCCTCGTT TGCCTCGTTT TCTCCTTGGC TACCCTGGTC 
CAGAGAGGAT ATGGAGACTT CGATGATTTC AATCTGGAGG ATGCGCTTAA AGAAACTTCC 
TCAGTAAAGC AGAGCCACTT TAGTACGACG ACTAGGAGGA CAGGAACGAC CAGAGCCCCA 
GCGAATCCAG CAGAGAGATG GGACCACATG ACCACTACTA CAACGAAAAG GCCAGGAACA 
ACTAGAGCAC CGTCAAATCC TCTGGAACTT GATGGGTTTG ACTTGGAAGA CGCCTTGGAT 
GATCGGAATG ATCTAGATGG CCCCAAAAAG CCAAGTACAG GAGAAGGAGG AGGTTTGTCA 
GACAAGGATC TCGAAGACAT CTTGGGAGGC GGGGGATACA AACCTGACAA GAATAAAGGT 
GGCGGTGGTG GTTATGGCAG CCAGGATGAC CCTGGATCAG GAGCAGTGAC GGACCCCGGC 
ACCATTGCGG GCCTGGTCAG CGCCCTGGCC GCGGCCCTCC TCGGAGCGGT GTCCGGCTAC 
CTCTCCTACC AGCATCGGAA GTTCTGTTTC AGTGTCCAGC GCGGCCTCGA CGCAGCCTAC 
GTGAAGGGGG AAAACCTGGA AGCTGTGGTG TGCGAGGAGC CCCGGGTGGA AGCCGCGATG 
TGCGAGGCGC CCCCAGTGAC GGACTCCACA CAACACTCGC AGCCCACAGA GCCCCTGGCA 
CCAGAGCGGC CCCGGATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cutting edge: Endothelial-specific gene ablation of CD99L2 impairs leukocyte extravasation in vivo.
Journal of immunology (Baltimore, Md. : 1950)190(3)892-6(2013 Feb)
Seelige R,Natsch C,M?rz S,Jing D,Frye M,Butz S,Vestweber D

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Nature cell biology13(4)383-93(2011 Apr)
Kuo JC,Han X,Hsiao CT,Yates JR 3rd,Waterman CM

A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo.
Blood109(12)5327-36(2007 Jun)
Bixel MG,Petri B,Khandoga AG,Khandoga A,Wolburg-Buchholz K,Wolburg H,M?rz S,Krombach F,Vestweber D

Cloning, genomic organization, alternative transcripts and expression analysis of CD99L2, a novel paralog of human CD99, and identification of evolutionary conserved motifs.
Gene30763-76(2003 Mar)
Suh YH,Shin YK,Kook MC,Oh KI,Park WS,Kim SH,Lee IS,Park HJ,Huh TL,Park SH

Molecular cloning of Rhombex-40 a transmembrane protein from the ventral medullary surface of the rat brain by differential display.
Life sciences66(22)2183-91(2000 Apr)
Shimokawa N,Jingu H,Okada J,Miura M