Dscam cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dscam
Entrez Gene ID	171119
Full Name	DS cell adhesion molecule
General protein information	Preferred Names DS cell adhesion molecule Names Down syndrome cell adhesion molecule homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q11
Summary	mouse homolog is a neural cell adhesion molecule; plays a role in axon guidance [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_133587.1	NP_598271.1	Down syndrome cell adhesion molecule homolog precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DSCAM	XP_001171538.1
Gallus gallus (chicken)	DSCAM	XP_416734.4
Danio rerio (zebrafish)	dscama	NP_001025395.1
Canis lupus familiaris (dog)	DSCAM	XP_005639051.1
Mus musculus (house mouse)	Dscam	NP_112451.1
Bos taurus (cattle)	DSCAM	XP_002685157.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007092	XP_308666.4
Homo sapiens (human)	DSCAM	NP_001380.2
	DSCAM	XP_002803170.1
Rattus norvegicus (Norway rat)	Dscam	NP_598271.1
Drosophila melanogaster (fruit fly)	Dscam4	NP_001137908.1
Xenopus tropicalis (tropical clawed frog)	dscam	NP_001136135.1

Gene Ontology
Bibliography

Related articles in PubMed

Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
Purohit AA, Li W, Qu C, Dwyer T, Shao Q, Guan KL, Liu G
The Journal of biological chemistry287(32)27126-38(2012 Aug)

Altered expression of Dscam in temporal lobe tissue from human and experimental animals.
Shen L, Xiao Z, Pan Y, Fang M, Li C, Chen D, Wang L, Xi Z, Xiao F, Wang X
Synapse (New York, N.Y.)65(10)975-82(2011 Oct)

DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina.
Fuerst PG, Bruce F, Tian M, Wei W, Elstrott J, Feller MB, Erskine L, Singer JH, Burgess RW
Neuron64(4)484-97(2009 Nov)

[Effects of DSCAM on differentiation of rat marrow mesenchymal stem cells into neurons in vitro].
Wang MC, Jia YJ, Wen QQ, Guan WJ, Zhao EY, Wang LD, Zhang BA
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics11(6)486-9(2009 Jun)

DSCAM functions as a netrin receptor in commissural axon pathfinding.
Liu G, Li W, Wang L, Kar A, Guan KL, Rao Y, Wu JY
Proceedings of the National Academy of Sciences of the United States of America106(8)2951-6(2009 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Dscam is highly expressed in rat brain during the different phases of experimental epilepsy.
Title: Altered expression of Dscam in temporal lobe tissue from human and experimental animals.

DSCAM may play an important role in mesenchymal stem cells (MSCs) differentiation into neural cells.
Title: [Effects of DSCAM on differentiation of rat marrow mesenchymal stem cells into neurons in vitro].

The following Dscam gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dscam cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01013	NM_133587.1 Latest version!	Rattus norvegicus DS cell adhesion molecule (Dscam), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	30	$1091.30 $1559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dscam ( NM_133587.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_598271.1 Rattus norvegicus DS cell adhesion molecule (Dscam), mRNA.

Price & Availability↑

CloneID	ORa01013
Clone ID Related Accession (Same CDS sequence)	NM_133587.1
Accession Version	NM_133587.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 6042bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	Down syndrome cell adhesion molecule homolog precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF334385.1. On Dec 17, 2003 this sequence version replaced XM_346413.1. ##Evidence-Data-START## Transcript exon combination :: AF334385.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTGGATAC TGGCTCTCTC CTTGTTCCAG AGCTTCGCGA ATGTTTTCAG TGAAGAGCCC 
CACTCCAGCC TCTACTTTGT CAATGCATCG CTGCAAGAGG TAGTGTTTGC AAGCACGTCG 
GGGACCCTGG TGCCCTGCCC GGCTGCAGGC ATCCCTCCTG TGACTCTCAG ATGGTACCTA 
GCAACGGGCG AGGAGATCTA CGATGTCCCT GGGATCCGCC ACGTCCATCC CAATGGCACT 
CTCCAAATTT TCCCCTTTCC TCCTTCAAGC TTCAGCACCT TAATCCATGA TAATACTTAC 
TATTGCACAG CTGAAAACCC TTCAGGGAAA ATTAGAAGTC AGGATGTCCA CATCAAGGCT 
GTTTTACGGG AGCCCTATAC AGTCCGTGTG GAGGACCAGA AAACCATGAG AGGCAATGTC 
GCGGTGTTCA AGTGCATTAT CCCCTCCTCG GTGGAGGCGT ACGTCACTGT CGTCTCATGG 
GAGAAAGACA CGGTTTCACT TGTCTCAGGA TCTAGATTTC TCATCACATC CACGGGAGCC 
TTGTATATTA AAGATGTACA GAACGAAGAT GGGCTGTACA ACTACCGCTG CATCACGCGG 
CACAGATACA CAGGGGAGAC GAGACAAAGC AACAGCGCGA GACTGTTCGT GTCAGACCCA 
GCGAACTCAG CCCCATCCAT CCTGGACGGG TTTGACCACC GCAAAGCCAT GGCAGGGCAG 
CGTGTGGAGC TGCCGTGCAA AGCTCTTGGG CACCCCGAGC CGGACTACCG CTGGCTGAAA 
GATAACATGC CCCTGGAACT TTCCGGAAGG TTCCAAAAGA CAGTGACCGG GCTGCTCATT 
GAGAACAGCC GCCCTTCAGA CTCAGGCAGC TACGTGTGTG AAGTATCCAA CCGATACGGC 
ACTGCCAAGG TGATAGGCCG CCTGTACGTG AAACAGCCAC TGAAAGCCAC CATCAGTCCC 
AGAAAGGTTA AAAGCAGTGT GGGCAGCCAG GTCTCCTTGT CCTGCAGTGT GACAGGAAAC 
GAAGACCAGG AGCTCTCCTG GTACAGAAAT GGTGAAATCC TCAACCCTGG GAAAAACGTG 
AGGATCACAG GACTCAACCA CGCGAACCTT ATAATGGATC ACATGGTCAA GAGTGATGGG 
GGCGCCTACC AGTGCTTTGT TCGCAAGGAC AAGCTATCTG CTCAAGACTA TGTCCAGGTG 
GTCCTTGAAG ACGGAACTCC CAAAATCATT TCCGCCTTTA GCGAGAAAGT GGTGAGCCCG 
GCAGAGCCAG TGTCCCTCGT GTGTAATGTG AAGGGTACAC CCTTGCCCAC GGTCACCTGG 
ACCCTGGACG ATGACCCCAT CCTCAAGGGC AGCGGCCACC GCATCAGCCA AATGATCACG 
TCCGAGGGGA ACGTGGTCAG CTACCTGAAT ATCTCCAGCT CCCAGGTCCG GGATGGGGGT 
GTCTACCGCT GCACTGCCAA CAACTCGGCT GGAGTCGTCC TGTACCAGGC TCGAATAAAC 
GTAAGAGGGC CGGCAAGCAT CAGACCGATG AAAAACATCA CTGCGATAGC AGGGCGTGAC 
ACGTACATCC ACTGCCGTGT GATTGGCTAC CCTTATTACT CCATCAAGTG GTACAAGAAC 
GCTAACCTGC TTCCTTTCAA CCACCGCCAG GTGGCGTTTG AGAACAATGG GACTCTGAAA 
CTCTCAGATG TGCAGAAAGA AGTTGACGAG GGAGAGTACA CATGTAACGT GCTGGTGCAG 
CCACAGCTCT CCACCAGCCA GAGTGTCCAC GTGACAGTCA AAGTTCCTCC TTTTATCCAA 
CCCTTTGAGT TCCCAAGATT CTCTATCGGT CAGCGGGTCT TCATCCCATG TGTGGTGGTC 
TCGGGGGACT TACCCATCAC CATCACCTGG CAGAAGGATG GCCGGCCGAT TCCAGCAAGC 
CTCGGTGTAA CCATCGACAA CATCGACTTC ACCAGCTCCC TGAGGATCTC CAACCTCTCA 
CTGATGCACA ACGGGAATTA CACCTGCATC GCGCGGAACG AGGCGGCCGC CGTGGAACAC 
CAGAGCCAGC TGATTGTAAG AGTTCCCCCT AAGTTCGTGG TCCAGCCCCG GGACCAGGAT 
GGGATCTATG GCAAAGCAGT GATTCTCAAT TGCTCTGCAG AGGGTTATCC TGTGCCTACA 
ATTGTGTGGA AATTCTCAAA AGGTGCTGGG GTCCCCCAGT TCCAGCCAAT TGCCCTGAAT 
GGCAGAATCC AGGTCCTGAG TAATGGCTCA CTCTTGATCA AGCATGTTGT GGAAGAAGAC 
AGTGGCTACT ACCTCTGCAA GGTCAGCAAC GATGTGGGCG CAGACGTCAG CAAGTCCATG 
TACCTCACGG TGAAAATTCC TGCCATGATA ACCTCTTATC CCAACACCAC CCTGGCCACT 
CAGGGTCAAA GGAAGGAGAT GAGCTGCACA GCACACGGGG AGAAGCCCAT CATTGTCCGC 
TGGGAGAAAG AGGACAGGAT CATTAACCCT GAAATGGCCC GTTACCTGGT GTCCACCAAG 
GAGGTGGGAG AGGAAGTGAT TTCTACTCTG CAGATTTTGC CAACAGTGAG AGAAGATTCC 
GGCTTCTTCT CCTGCCATGC TATCAATTCA TATGGGGAGG ACCGCGGAAT AATTCAGCTC 
ACGGTGCAAG AACCCCCAGA CCCCCCCGAG ATTGAGATCA AAGATGTCAA AGCCCGCACA 
ATCACGCTCA GGTGGACCAT GGGGTTTGAT GGCAACAGCC CCATCACAGG CTACGACATT 
GAGTGCAAAA ATAAATCAGA CTCCTGGGAT TCTGCTCAAA GAACCAAAGA TGTTTCCCCT 
CAGCTGAACT CGGCCACCAT CATTGATATC CACCCTTCCT CCACCTACAG CATCCGCATG 
TACGCCAAGA ACCGGATTGG CAAGAGTGAG CCCAGCAACG AGATCACCAT CACGGCAGAT 
GAGGCAGCTC CTGATGGTCC ACCTCAGGAA GTGCACCTGG AACCCACCTC ATCTCAGAGT 
ATCAGGGTTA CCTGGAAGGC TCCCAAGAAA CATTTACAAA ATGGGATCAT ACGTGGCTAC 
CAGATAGGCT ACCGGGAGTA CAGCACCGGG GGCAACTTCC AGTTCAACAT CATCAGTATC 
GACACCACCG GGGACAGCGA AGTGTACACC CTGGACAACC TGAATAAGTT CACCCAGTAT 
GGCCTAGTAG TACAGGCCTG CAACCGGGCC GGCACGGGAC CTTCTTCTCA GGAGATAATC 
ACTACCACCC TGGAGGACGT ACCCAGCTAC CCTCCCGAAA ATGTCCAAGC CATAGCAACC 
TCACCAGAAA GCATATCAAT CTCCTGGTCC ACGCTGTCCA AGGAGGCCTT GAATGGGATT 
CTCCAGGGGT TCAGGGTCAT CTACTGGGCC AACCTCATAG ACGGAGAGCT GGGCGAGATT 
AAGAACGTCA CCACCACGCA GCCTTCCTTG GAGTTGGATG GACTAGAGAA ATACACCAAC 
TACAGTATCC AGGTGCTGGC CTTCACCCGT GCAGGGGACG GCGTCCGGAG TGAGCAGATC 
TTTACCCGTA CCAAGGAGGA TGTTCCAGGT CCTCCTGCTG GTGTCAAGGC AGCAGCAGCC 
TCGGCCTCCA TGGTCTTTGT GTCCTGGCTG CCCCCGCTCA AGCTGAATGG CATCATTCGG 
AAGTACACGG TGTTCTGCTC CCACCCCTAC CCCACAGTCA TCAGCGAGTT TGAAGCCTCC 
CCTGACTCAT TTTCCTACAG AATTCCTAAC CTGAGTCGGA ATCGACAGTA TAGCGTCTGG 
GTGGTGGCAG TGACTTCCGC CGGAAGAGGC AACAGCAGTG AGATCATCAC CGTGGAGCCT 
CTGGCTAAAG CTCCTGCACG GATCCTCACG TTCAGTGGGA CAGTGACTAC TCCGTGGATG 
AAGGACATCG TCTTGCCGTG TAAAGCTGTT GGAGACCCAT CACCTGCCGT AAAATGGATG 
AAGGATAGTA ACGGGACGCC CAGCCTGGTG ACGATTGATG GCCGCAGAAG CATCTTCAGC 
AATGGGAGTT TCGTTATTCG CACGGTGAAG GCCGAGGACT CTGGCTACTA CAGCTGTGTT 
GCCAATAACA ACTGGGGATC AGATGAGATC ATATTAAATT TGCAAGTACA AGTTCCACCA 
GATCAGCCTC GGCTCACCGT ATCCAAGACG ACATCCTCCT CCATCACCCT TTCCTGGCTT 
CCTGGAGACA ATGGGGGCAG CTCCATCAGA GGCTACATCC TGCAATATTC CGAGGACAAC 
AGTGAGCAGT GGGGGAGCTT TCCCATCAGC CCCAGCGAGC GTTCCTACCG CTTGGAAAAC 
CTAAAGTGTG GGACATGGTA TAAGTTCACC CTTACTGCCC AAAATGGAGT GGGACCCGGA 
CGCATAAGTG AAATCATAGA AGCCAAAACT CTGGGGAAAG AACCCCAGTT CTCCAAGGAG 
CAGGAGCTCT TCGCCAGCAT CAATACCACC CGAGTGAGGC TGAATCTGAT TGGCTGGAAC 
GACGGCGGCT GTCCAATCAC CTCATTCACT CTTGAGTACA GACCCTTCGG GACCACGGTC 
TGGACCACAG CTCAGCGGAC CTCCCTTTCC AAGTCTTACA TTCTGTATGA CCTCCAAGAA 
GCCACATGGT ATGAACTGCA GATGCGAGTG TGCAACAGCG CCGGCTGCGC AGAGAAGCAA 
GCCAACTTTG CCACGCTGAA CTACGATGGC AGTACAATCC CTCCACTCAT TAAGTCAGTT 
GTCCAAAGCG AAGAAGGGCT GACAACCAAC GAAGGGCTCA AGATCCTCGT GACCATCTCC 
TGCATCCTGG TCGGGGTTCT GCTGCTCTTT GTGCTTCTGC TGGTGGTGCG AAGGAGACGG 
AGGGAGCAGA GGCTGAAGAG GCTGAGAGAT GCAAAGAGTT TAGCTGAGAT GCTCATGAGC 
AAGAACACAC GGACTTCAGA TACCTTGAGC AAACAGCAAC AGACTCTGAG GATGCACATT 
GATATACCCA GGGCTCAGCT TTTGATTGAA GAGAGAGACA CAATGGAGAC CATAGATGAC 
CGCTCCACAG TCCTGTTAAC GGATGCTGAC TTTGGGGAGG CAGCCAAACA GAAGTCACTG 
ACGGTGACTC ACACGGTGCA TTACCAATCG GTGTCTCAGG CCACCGGGCC CCTAGTGGAT 
GTCTCCGATG CTCGGCCAGG AACGAATCCC ACCACCAGGA GGAATGCAAA GGCTGGACCC 
ACAGCAAGAA ACCGGTACGC CAGCCAGTGG ACCCTCAACA GACCCCACCC CACCATCTCA 
GCACACACTC TCACCACAGA CTGGAGACTG CCTACCCCCA GGGCTACAGG CTCCGTGGAC 
AAGGAAAGTG ACAGCTACAG CGTCAGCCCA TCACAAGACA CAGACAGAGC AAGGAGCAGC 
ATGGTCTCCA CAGAAAGTGC CTCCTCTACC TACGAAGAAC TGGCCAGGGC CTACGAGCAC 
GCCAAGATGG AGGAGCAGCT GAGGCACGCC AAGTTCACCA TCACAGAGTG CTTCATATCC 
GACACGTCCT CCGAGCAGCT GACGGCAGGG ACAAACGAGT ACACGGACAG TCTGACCTCC 
AGTACCCCTT CAGAATCGGG GATCTGCAGA TTCACTGCGT CTCCCCCCAA ACCTCAGGAT 
GGAGGTCGTG TGGTGAACAT GGCGGTTCCA AAGGCCCATC GGCCAGGCGA CCTCATACAC 
CTGCCTCCAT ACCTGCGAAT GGACTTCTTG TTAAACCGGG GCGCACCAGG CACCAGCAGG 
GACCTGAGCT TAGGACAAGC GTGCTTGGAA CCCCAGAAAA GTCGGACCCT GAAGCGCCCC 
ACGGTCCTTG AGCCCACCCC TATGGAGGCT TCCTCCTCCA CCTCTTCCAC GAGAGAAGGA 
CAGCAGTCGT GGCAACAAGG GGCCGTGGCC ACCTTACCTC AGCGAGAGGG TGCAGAGCTG 
GGACAGGCAG CTAAAATGAG CAGCTCCCAA GAGTCGCTGC TGGACTCTCG GGGCCACTTG 
AAAGGAAACA ATCCCTACGC AAAATCCTAC ACCTTGGTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598271.1
CDS	477..6518
Translation	MWILALSLFQSFANVFSEEPHSSLYFVNASLQEVVFASTSGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYVTVVSWEKDTVSLVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENSRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGNEDQELSWYRNGEILNPGKNVRITGLNHANLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLVCNVKGTPLPTVTWTLDDDPILKGSGHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNANLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPASLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQRKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNEITITADEAAPDGPPQEVHLEPTSSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISIDTTGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLIDGELGEIKNVTTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFVIRTVKAEDSGYYSCVANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQSEEGLTTNEGLKILVTISCILVGVLLLFVLLLVVRRRRREQRLKRLRDAKSLAEMLMSKNTRTSDTLSKQQQTLRMHIDIPRAQLLIEERDTMETIDDRSTVLLTDADFGEAAKQKSLTVTHTVHYQSVSQATGPLVDVSDARPGTNPTTRRNAKAGPTARNRYASQWTLNRPHPTISAHTLTTDWRLPTPRATGSVDKESDSYSVSPSQDTDRARSSMVSTESASSTYEELARAYEHAKMEEQLRHAKFTITECFISDTSSEQLTAGTNEYTDSLTSSTPSESGICRFTASPPKPQDGGRVVNMAVPKAHRPGDLIHLPPYLRMDFLLNRGAPGTSRDLSLGQACLEPQKSRTLKRPTVLEPTPMEASSSTSSTREGQQSWQQGAVATLPQREGAELGQAAKMSSSQESLLDSRGHLKGNNPYAKSYTLV

Target ORF information:

RefSeq Version	NM_133587.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus DS cell adhesion molecule (Dscam), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133587.1

ORF Insert Sequence:

ATGTGGATAC TGGCTCTCTC CTTGTTCCAG AGCTTCGCGA ATGTTTTCAG TGAAGAGCCC 
CACTCCAGCC TCTACTTTGT CAATGCATCG CTGCAAGAGG TAGTGTTTGC AAGCACGTCG 
GGGACCCTGG TGCCCTGCCC GGCTGCAGGC ATCCCTCCTG TGACTCTCAG ATGGTACCTA 
GCAACGGGCG AGGAGATCTA CGATGTCCCT GGGATCCGCC ACGTCCATCC CAATGGCACT 
CTCCAAATTT TCCCCTTTCC TCCTTCAAGC TTCAGCACCT TAATCCATGA TAATACTTAC 
TATTGCACAG CTGAAAACCC TTCAGGGAAA ATTAGAAGTC AGGATGTCCA CATCAAGGCT 
GTTTTACGGG AGCCCTATAC AGTCCGTGTG GAGGACCAGA AAACCATGAG AGGCAATGTC 
GCGGTGTTCA AGTGCATTAT CCCCTCCTCG GTGGAGGCGT ACGTCACTGT CGTCTCATGG 
GAGAAAGACA CGGTTTCACT TGTCTCAGGA TCTAGATTTC TCATCACATC CACGGGAGCC 
TTGTATATTA AAGATGTACA GAACGAAGAT GGGCTGTACA ACTACCGCTG CATCACGCGG 
CACAGATACA CAGGGGAGAC GAGACAAAGC AACAGCGCGA GACTGTTCGT GTCAGACCCA 
GCGAACTCAG CCCCATCCAT CCTGGACGGG TTTGACCACC GCAAAGCCAT GGCAGGGCAG 
CGTGTGGAGC TGCCGTGCAA AGCTCTTGGG CACCCCGAGC CGGACTACCG CTGGCTGAAA 
GATAACATGC CCCTGGAACT TTCCGGAAGG TTCCAAAAGA CAGTGACCGG GCTGCTCATT 
GAGAACAGCC GCCCTTCAGA CTCAGGCAGC TACGTGTGTG AAGTATCCAA CCGATACGGC 
ACTGCCAAGG TGATAGGCCG CCTGTACGTG AAACAGCCAC TGAAAGCCAC CATCAGTCCC 
AGAAAGGTTA AAAGCAGTGT GGGCAGCCAG GTCTCCTTGT CCTGCAGTGT GACAGGAAAC 
GAAGACCAGG AGCTCTCCTG GTACAGAAAT GGTGAAATCC TCAACCCTGG GAAAAACGTG 
AGGATCACAG GACTCAACCA CGCGAACCTT ATAATGGATC ACATGGTCAA GAGTGATGGG 
GGCGCCTACC AGTGCTTTGT TCGCAAGGAC AAGCTATCTG CTCAAGACTA TGTCCAGGTG 
GTCCTTGAAG ACGGAACTCC CAAAATCATT TCCGCCTTTA GCGAGAAAGT GGTGAGCCCG 
GCAGAGCCAG TGTCCCTCGT GTGTAATGTG AAGGGTACAC CCTTGCCCAC GGTCACCTGG 
ACCCTGGACG ATGACCCCAT CCTCAAGGGC AGCGGCCACC GCATCAGCCA AATGATCACG 
TCCGAGGGGA ACGTGGTCAG CTACCTGAAT ATCTCCAGCT CCCAGGTCCG GGATGGGGGT 
GTCTACCGCT GCACTGCCAA CAACTCGGCT GGAGTCGTCC TGTACCAGGC TCGAATAAAC 
GTAAGAGGGC CGGCAAGCAT CAGACCGATG AAAAACATCA CTGCGATAGC AGGGCGTGAC 
ACGTACATCC ACTGCCGTGT GATTGGCTAC CCTTATTACT CCATCAAGTG GTACAAGAAC 
GCTAACCTGC TTCCTTTCAA CCACCGCCAG GTGGCGTTTG AGAACAATGG GACTCTGAAA 
CTCTCAGATG TGCAGAAAGA AGTTGACGAG GGAGAGTACA CATGTAACGT GCTGGTGCAG 
CCACAGCTCT CCACCAGCCA GAGTGTCCAC GTGACAGTCA AAGTTCCTCC TTTTATCCAA 
CCCTTTGAGT TCCCAAGATT CTCTATCGGT CAGCGGGTCT TCATCCCATG TGTGGTGGTC 
TCGGGGGACT TACCCATCAC CATCACCTGG CAGAAGGATG GCCGGCCGAT TCCAGCAAGC 
CTCGGTGTAA CCATCGACAA CATCGACTTC ACCAGCTCCC TGAGGATCTC CAACCTCTCA 
CTGATGCACA ACGGGAATTA CACCTGCATC GCGCGGAACG AGGCGGCCGC CGTGGAACAC 
CAGAGCCAGC TGATTGTAAG AGTTCCCCCT AAGTTCGTGG TCCAGCCCCG GGACCAGGAT 
GGGATCTATG GCAAAGCAGT GATTCTCAAT TGCTCTGCAG AGGGTTATCC TGTGCCTACA 
ATTGTGTGGA AATTCTCAAA AGGTGCTGGG GTCCCCCAGT TCCAGCCAAT TGCCCTGAAT 
GGCAGAATCC AGGTCCTGAG TAATGGCTCA CTCTTGATCA AGCATGTTGT GGAAGAAGAC 
AGTGGCTACT ACCTCTGCAA GGTCAGCAAC GATGTGGGCG CAGACGTCAG CAAGTCCATG 
TACCTCACGG TGAAAATTCC TGCCATGATA ACCTCTTATC CCAACACCAC CCTGGCCACT 
CAGGGTCAAA GGAAGGAGAT GAGCTGCACA GCACACGGGG AGAAGCCCAT CATTGTCCGC 
TGGGAGAAAG AGGACAGGAT CATTAACCCT GAAATGGCCC GTTACCTGGT GTCCACCAAG 
GAGGTGGGAG AGGAAGTGAT TTCTACTCTG CAGATTTTGC CAACAGTGAG AGAAGATTCC 
GGCTTCTTCT CCTGCCATGC TATCAATTCA TATGGGGAGG ACCGCGGAAT AATTCAGCTC 
ACGGTGCAAG AACCCCCAGA CCCCCCCGAG ATTGAGATCA AAGATGTCAA AGCCCGCACA 
ATCACGCTCA GGTGGACCAT GGGGTTTGAT GGCAACAGCC CCATCACAGG CTACGACATT 
GAGTGCAAAA ATAAATCAGA CTCCTGGGAT TCTGCTCAAA GAACCAAAGA TGTTTCCCCT 
CAGCTGAACT CGGCCACCAT CATTGATATC CACCCTTCCT CCACCTACAG CATCCGCATG 
TACGCCAAGA ACCGGATTGG CAAGAGTGAG CCCAGCAACG AGATCACCAT CACGGCAGAT 
GAGGCAGCTC CTGATGGTCC ACCTCAGGAA GTGCACCTGG AACCCACCTC ATCTCAGAGT 
ATCAGGGTTA CCTGGAAGGC TCCCAAGAAA CATTTACAAA ATGGGATCAT ACGTGGCTAC 
CAGATAGGCT ACCGGGAGTA CAGCACCGGG GGCAACTTCC AGTTCAACAT CATCAGTATC 
GACACCACCG GGGACAGCGA AGTGTACACC CTGGACAACC TGAATAAGTT CACCCAGTAT 
GGCCTAGTAG TACAGGCCTG CAACCGGGCC GGCACGGGAC CTTCTTCTCA GGAGATAATC 
ACTACCACCC TGGAGGACGT ACCCAGCTAC CCTCCCGAAA ATGTCCAAGC CATAGCAACC 
TCACCAGAAA GCATATCAAT CTCCTGGTCC ACGCTGTCCA AGGAGGCCTT GAATGGGATT 
CTCCAGGGGT TCAGGGTCAT CTACTGGGCC AACCTCATAG ACGGAGAGCT GGGCGAGATT 
AAGAACGTCA CCACCACGCA GCCTTCCTTG GAGTTGGATG GACTAGAGAA ATACACCAAC 
TACAGTATCC AGGTGCTGGC CTTCACCCGT GCAGGGGACG GCGTCCGGAG TGAGCAGATC 
TTTACCCGTA CCAAGGAGGA TGTTCCAGGT CCTCCTGCTG GTGTCAAGGC AGCAGCAGCC 
TCGGCCTCCA TGGTCTTTGT GTCCTGGCTG CCCCCGCTCA AGCTGAATGG CATCATTCGG 
AAGTACACGG TGTTCTGCTC CCACCCCTAC CCCACAGTCA TCAGCGAGTT TGAAGCCTCC 
CCTGACTCAT TTTCCTACAG AATTCCTAAC CTGAGTCGGA ATCGACAGTA TAGCGTCTGG 
GTGGTGGCAG TGACTTCCGC CGGAAGAGGC AACAGCAGTG AGATCATCAC CGTGGAGCCT 
CTGGCTAAAG CTCCTGCACG GATCCTCACG TTCAGTGGGA CAGTGACTAC TCCGTGGATG 
AAGGACATCG TCTTGCCGTG TAAAGCTGTT GGAGACCCAT CACCTGCCGT AAAATGGATG 
AAGGATAGTA ACGGGACGCC CAGCCTGGTG ACGATTGATG GCCGCAGAAG CATCTTCAGC 
AATGGGAGTT TCGTTATTCG CACGGTGAAG GCCGAGGACT CTGGCTACTA CAGCTGTGTT 
GCCAATAACA ACTGGGGATC AGATGAGATC ATATTAAATT TGCAAGTACA AGTTCCACCA 
GATCAGCCTC GGCTCACCGT ATCCAAGACG ACATCCTCCT CCATCACCCT TTCCTGGCTT 
CCTGGAGACA ATGGGGGCAG CTCCATCAGA GGCTACATCC TGCAATATTC CGAGGACAAC 
AGTGAGCAGT GGGGGAGCTT TCCCATCAGC CCCAGCGAGC GTTCCTACCG CTTGGAAAAC 
CTAAAGTGTG GGACATGGTA TAAGTTCACC CTTACTGCCC AAAATGGAGT GGGACCCGGA 
CGCATAAGTG AAATCATAGA AGCCAAAACT CTGGGGAAAG AACCCCAGTT CTCCAAGGAG 
CAGGAGCTCT TCGCCAGCAT CAATACCACC CGAGTGAGGC TGAATCTGAT TGGCTGGAAC 
GACGGCGGCT GTCCAATCAC CTCATTCACT CTTGAGTACA GACCCTTCGG GACCACGGTC 
TGGACCACAG CTCAGCGGAC CTCCCTTTCC AAGTCTTACA TTCTGTATGA CCTCCAAGAA 
GCCACATGGT ATGAACTGCA GATGCGAGTG TGCAACAGCG CCGGCTGCGC AGAGAAGCAA 
GCCAACTTTG CCACGCTGAA CTACGATGGC AGTACAATCC CTCCACTCAT TAAGTCAGTT 
GTCCAAAGCG AAGAAGGGCT GACAACCAAC GAAGGGCTCA AGATCCTCGT GACCATCTCC 
TGCATCCTGG TCGGGGTTCT GCTGCTCTTT GTGCTTCTGC TGGTGGTGCG AAGGAGACGG 
AGGGAGCAGA GGCTGAAGAG GCTGAGAGAT GCAAAGAGTT TAGCTGAGAT GCTCATGAGC 
AAGAACACAC GGACTTCAGA TACCTTGAGC AAACAGCAAC AGACTCTGAG GATGCACATT 
GATATACCCA GGGCTCAGCT TTTGATTGAA GAGAGAGACA CAATGGAGAC CATAGATGAC 
CGCTCCACAG TCCTGTTAAC GGATGCTGAC TTTGGGGAGG CAGCCAAACA GAAGTCACTG 
ACGGTGACTC ACACGGTGCA TTACCAATCG GTGTCTCAGG CCACCGGGCC CCTAGTGGAT 
GTCTCCGATG CTCGGCCAGG AACGAATCCC ACCACCAGGA GGAATGCAAA GGCTGGACCC 
ACAGCAAGAA ACCGGTACGC CAGCCAGTGG ACCCTCAACA GACCCCACCC CACCATCTCA 
GCACACACTC TCACCACAGA CTGGAGACTG CCTACCCCCA GGGCTACAGG CTCCGTGGAC 
AAGGAAAGTG ACAGCTACAG CGTCAGCCCA TCACAAGACA CAGACAGAGC AAGGAGCAGC 
ATGGTCTCCA CAGAAAGTGC CTCCTCTACC TACGAAGAAC TGGCCAGGGC CTACGAGCAC 
GCCAAGATGG AGGAGCAGCT GAGGCACGCC AAGTTCACCA TCACAGAGTG CTTCATATCC 
GACACGTCCT CCGAGCAGCT GACGGCAGGG ACAAACGAGT ACACGGACAG TCTGACCTCC 
AGTACCCCTT CAGAATCGGG GATCTGCAGA TTCACTGCGT CTCCCCCCAA ACCTCAGGAT 
GGAGGTCGTG TGGTGAACAT GGCGGTTCCA AAGGCCCATC GGCCAGGCGA CCTCATACAC 
CTGCCTCCAT ACCTGCGAAT GGACTTCTTG TTAAACCGGG GCGCACCAGG CACCAGCAGG 
GACCTGAGCT TAGGACAAGC GTGCTTGGAA CCCCAGAAAA GTCGGACCCT GAAGCGCCCC 
ACGGTCCTTG AGCCCACCCC TATGGAGGCT TCCTCCTCCA CCTCTTCCAC GAGAGAAGGA 
CAGCAGTCGT GGCAACAAGG GGCCGTGGCC ACCTTACCTC AGCGAGAGGG TGCAGAGCTG 
GGACAGGCAG CTAAAATGAG CAGCTCCCAA GAGTCGCTGC TGGACTCTCG GGGCCACTTG 
AAAGGAAACA ATCCCTACGC AAAATCCTAC ACCTTGGTAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
The Journal of biological chemistry287(32)27126-38(2012 Aug)
Purohit AA,Li W,Qu C,Dwyer T,Shao Q,Guan KL,Liu G

Altered expression of Dscam in temporal lobe tissue from human and experimental animals.
Synapse (New York, N.Y.)65(10)975-82(2011 Oct)
Shen L,Xiao Z,Pan Y,Fang M,Li C,Chen D,Wang L,Xi Z,Xiao F,Wang X

DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina.
Neuron64(4)484-97(2009 Nov)
Fuerst PG,Bruce F,Tian M,Wei W,Elstrott J,Feller MB,Erskine L,Singer JH,Burgess RW

[Effects of DSCAM on differentiation of rat marrow mesenchymal stem cells into neurons in vitro].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics11(6)486-9(2009 Jun)
Wang MC,Jia YJ,Wen QQ,Guan WJ,Zhao EY,Wang LD,Zhang BA

DSCAM functions as a netrin receptor in commissural axon pathfinding.
Proceedings of the National Academy of Sciences of the United States of America106(8)2951-6(2009 Feb)
Liu G,Li W,Wang L,Kar A,Guan KL,Rao Y,Wu JY

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Dscam cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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