Cacng5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cacng5
Entrez Gene ID	140726
Full Name	calcium voltage-gated channel auxiliary subunit gamma 5
General protein information	Preferred Names calcium voltage-gated channel auxiliary subunit gamma 5 Names voltage-dependent calcium channel gamma-5 subunit TARP gamma-5 calcium channel, voltage-dependent, gamma subunit 5 neuronal voltage-gated calcium channel gamma-5 subunit transmembrane AMPAR regulatory protein gamma-5
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.1
Summary	member of a family of gamma subunits of voltage-dependent calcium channels [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_080693.1	NP_542424.1	voltage-dependent calcium channel gamma-5 subunit
XM_017596974.1	XP_017452463.1	voltage-dependent calcium channel gamma-5 subunit isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CACNG5	NP_665810.1
Canis lupus familiaris (dog)	CACNG5	XP_548027.2
Mus musculus (house mouse)	Cacng5	NP_001186230.1
Rattus norvegicus (Norway rat)	Cacng5	NP_542424.1
Gallus gallus (chicken)	CACNG7	XP_415681.3
Danio rerio (zebrafish)	LOC100331116	XP_002661320.1
Bos taurus (cattle)	CACNG5	NP_001192891.1
Pan troglodytes (chimpanzee)	CACNG5	XP_003315735.1
Gallus gallus (chicken)	LOC100859614	XP_003642391.2

Gene Ontology
Bibliography

Related articles in PubMed

Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors.
Schwenk J, Harmel N, Zolles G, Bildl W, Kulik A, Heimrich B, Chisaka O, Jonas P, Schulte U, Fakler B, Kl?cker N
Science (New York, N.Y.)323(5919)1313-9(2009 Mar)

Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, gamma-5.
Soto D, Coombs ID, Renzi M, Zonouzi M, Farrant M, Cull-Candy SG
Nature neuroscience12(3)277-85(2009 Mar)

AMPA receptor subunit-specific regulation by a distinct family of type II TARPs.
Kato AS, Siuda ER, Nisenbaum ES, Bredt DS
Neuron59(6)986-96(2008 Sep)

Calcium channel gamma subunits provide insights into the evolution of this gene family.
Chu PJ, Robertson HM, Best PM
Gene280(1-2)37-48(2001 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Whereas gamma-5 interacts with all AMPA-type glutamate receptor subunits, it predominantly regulates the functions of calcium-permeable AMPA receptor subunit combinations lacking short-form subunits in Bergmann glia.
Title: Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, gamma-5.

The following Cacng5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cacng5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00111	NM_080693.1 Latest version!	Rattus norvegicus calcium voltage-gated channel auxiliary subunit gamma 5 (Cacng5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa00111	XM_017596974.1 Latest version!	Rattus norvegicus calcium voltage-gated channel auxiliary subunit gamma 5 (Cacng5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cacng5 ( NM_080693.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_542424.1 Rattus norvegicus calcium voltage-gated channel auxiliary subunit gamma 5 (Cacng5), mRNA.

Price & Availability↑

CloneID	ORa00111
Clone ID Related Accession (Same CDS sequence)	NM_080693.1 , XM_017596974.1
Accession Version	NM_080693.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 828bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Rattus norvegicus(Norway rat)
Product	voltage-dependent calcium channel gamma-5 subunit
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF361342.1. On Dec 17, 2003 this sequence version replaced XM_346411.1. ##Evidence-Data-START## Transcript exon combination :: AF361342.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGCACCT GTGGGAGGAA GGCCCTGACC CTGCTGAGCA GTGTCTTTGC TGTCTGTGGC 
CTGGGCCTGC TGGGCATCGC GGTCAGCACG GACTACTGGC TGTACTTGGA AGAAGGCATA 
ATCCTTCCCC AGAACCAGAG CACGGAGGTC AAGATGTCCC TGCACTCGGG CCTCTGGCGG 
GTCTGCTTCC TCGCAGGTGA GGAGCGAGGA CGCTGTTTCA CCATAGAGTA TGTGATGCCC 
ATGAACTCCC AGATGACGTC AGAATCCACA GTCAATGTTC TAAAAATGAT TCGCTCGGCC 
ACCCCGTTCC CACTGGTCAG CCTATTCTTC ATGTTCATCG GGTTCATCCT GAGCAACATC 
GGACACATCC GTCCGCACCG GACCATACTG GCTTTTGTCT CTGGCATCTT CTTTATCCTA 
TCCGGCCTCT CTCTTGTGGT GGGCCTGGTG CTGTACATCT CCAGCATCAA TGACGAGATG 
CTCAACAGAA CCAAGGATGC AGAGACCTAT TTCAACTACA AATATGGATG GTCGTTTGCC 
TTTGCTGCCA TCTCCTTCCT CTTAACAGAG AGTGCTGGGG TGATGTCTGT GTATCTGTTT 
ATGAAGAGGT ATACTGCTGA GGACATGTAC AGGCCCCACC CAGGCTTCTA CCGGCCACGG 
CTGAGCAACT GTTCTGATTA CTCTGGCCAG TTTCTACATC CAGATGCCTG GATCCGGGGC 
CGCAGCCCCT CGGACATCTC CAGTGATGCC TCCCTACAGA TGAACAGTAA CTACCCAGCT 
TTGCTCAAGT GCCCAGACTA TGACCAGATG TCATCATCTC CCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542424.1
CDS	1..828
Translation	MSTCGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGIILPQNQSTEVKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNSQMTSESTVNVLKMIRSATPFPLVSLFFMFIGFILSNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWIRGRSPSDISSDASLQMNSNYPALLKCPDYDQMSSSPC

Target ORF information:

RefSeq Version	NM_080693.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium voltage-gated channel auxiliary subunit gamma 5 (Cacng5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080693.1

ORF Insert Sequence:

ATGAGCACCT GTGGGAGGAA GGCCCTGACC CTGCTGAGCA GTGTCTTTGC TGTCTGTGGC 
CTGGGCCTGC TGGGCATCGC GGTCAGCACG GACTACTGGC TGTACTTGGA AGAAGGCATA 
ATCCTTCCCC AGAACCAGAG CACGGAGGTC AAGATGTCCC TGCACTCGGG CCTCTGGCGG 
GTCTGCTTCC TCGCAGGTGA GGAGCGAGGA CGCTGTTTCA CCATAGAGTA TGTGATGCCC 
ATGAACTCCC AGATGACGTC AGAATCCACA GTCAATGTTC TAAAAATGAT TCGCTCGGCC 
ACCCCGTTCC CACTGGTCAG CCTATTCTTC ATGTTCATCG GGTTCATCCT GAGCAACATC 
GGACACATCC GTCCGCACCG GACCATACTG GCTTTTGTCT CTGGCATCTT CTTTATCCTA 
TCCGGCCTCT CTCTTGTGGT GGGCCTGGTG CTGTACATCT CCAGCATCAA TGACGAGATG 
CTCAACAGAA CCAAGGATGC AGAGACCTAT TTCAACTACA AATATGGATG GTCGTTTGCC 
TTTGCTGCCA TCTCCTTCCT CTTAACAGAG AGTGCTGGGG TGATGTCTGT GTATCTGTTT 
ATGAAGAGGT ATACTGCTGA GGACATGTAC AGGCCCCACC CAGGCTTCTA CCGGCCACGG 
CTGAGCAACT GTTCTGATTA CTCTGGCCAG TTTCTACATC CAGATGCCTG GATCCGGGGC 
CGCAGCCCCT CGGACATCTC CAGTGATGCC TCCCTACAGA TGAACAGTAA CTACCCAGCT 
TTGCTCAAGT GCCCAGACTA TGACCAGATG TCATCATCTC CCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cacng5 ( XM_017596974.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452463.1 Rattus norvegicus calcium voltage-gated channel auxiliary subunit gamma 5 (Cacng5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa00111
Clone ID Related Accession (Same CDS sequence)	NM_080693.1 , XM_017596974.1
Accession Version	XM_017596974.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 828bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	voltage-dependent calcium channel gamma-5 subunit isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCACCT GTGGGAGGAA GGCCCTGACC CTGCTGAGCA GTGTCTTTGC TGTCTGTGGC 
CTGGGCCTGC TGGGCATCGC GGTCAGCACG GACTACTGGC TGTACTTGGA AGAAGGCATA 
ATCCTTCCCC AGAACCAGAG CACGGAGGTC AAGATGTCCC TGCACTCGGG CCTCTGGCGG 
GTCTGCTTCC TCGCAGGTGA GGAGCGAGGA CGCTGTTTCA CCATAGAGTA TGTGATGCCC 
ATGAACTCCC AGATGACGTC AGAATCCACA GTCAATGTTC TAAAAATGAT TCGCTCGGCC 
ACCCCGTTCC CACTGGTCAG CCTATTCTTC ATGTTCATCG GGTTCATCCT GAGCAACATC 
GGACACATCC GTCCGCACCG GACCATACTG GCTTTTGTCT CTGGCATCTT CTTTATCCTA 
TCCGGCCTCT CTCTTGTGGT GGGCCTGGTG CTGTACATCT CCAGCATCAA TGACGAGATG 
CTCAACAGAA CCAAGGATGC AGAGACCTAT TTCAACTACA AATATGGATG GTCGTTTGCC 
TTTGCTGCCA TCTCCTTCCT CTTAACAGAG AGTGCTGGGG TGATGTCTGT GTATCTGTTT 
ATGAAGAGGT ATACTGCTGA GGACATGTAC AGGCCCCACC CAGGCTTCTA CCGGCCACGG 
CTGAGCAACT GTTCTGATTA CTCTGGCCAG TTTCTACATC CAGATGCCTG GATCCGGGGC 
CGCAGCCCCT CGGACATCTC CAGTGATGCC TCCCTACAGA TGAACAGTAA CTACCCAGCT 
TTGCTCAAGT GCCCAGACTA TGACCAGATG TCATCATCTC CCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452463.1
CDS	220..1047
Translation	MSTCGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGIILPQNQSTEVKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNSQMTSESTVNVLKMIRSATPFPLVSLFFMFIGFILSNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWIRGRSPSDISSDASLQMNSNYPALLKCPDYDQMSSSPC

Target ORF information:

RefSeq Version	XM_017596974.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calcium voltage-gated channel auxiliary subunit gamma 5 (Cacng5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017596974.1

ORF Insert Sequence:

ATGAGCACCT GTGGGAGGAA GGCCCTGACC CTGCTGAGCA GTGTCTTTGC TGTCTGTGGC 
CTGGGCCTGC TGGGCATCGC GGTCAGCACG GACTACTGGC TGTACTTGGA AGAAGGCATA 
ATCCTTCCCC AGAACCAGAG CACGGAGGTC AAGATGTCCC TGCACTCGGG CCTCTGGCGG 
GTCTGCTTCC TCGCAGGTGA GGAGCGAGGA CGCTGTTTCA CCATAGAGTA TGTGATGCCC 
ATGAACTCCC AGATGACGTC AGAATCCACA GTCAATGTTC TAAAAATGAT TCGCTCGGCC 
ACCCCGTTCC CACTGGTCAG CCTATTCTTC ATGTTCATCG GGTTCATCCT GAGCAACATC 
GGACACATCC GTCCGCACCG GACCATACTG GCTTTTGTCT CTGGCATCTT CTTTATCCTA 
TCCGGCCTCT CTCTTGTGGT GGGCCTGGTG CTGTACATCT CCAGCATCAA TGACGAGATG 
CTCAACAGAA CCAAGGATGC AGAGACCTAT TTCAACTACA AATATGGATG GTCGTTTGCC 
TTTGCTGCCA TCTCCTTCCT CTTAACAGAG AGTGCTGGGG TGATGTCTGT GTATCTGTTT 
ATGAAGAGGT ATACTGCTGA GGACATGTAC AGGCCCCACC CAGGCTTCTA CCGGCCACGG 
CTGAGCAACT GTTCTGATTA CTCTGGCCAG TTTCTACATC CAGATGCCTG GATCCGGGGC 
CGCAGCCCCT CGGACATCTC CAGTGATGCC TCCCTACAGA TGAACAGTAA CTACCCAGCT 
TTGCTCAAGT GCCCAGACTA TGACCAGATG TCATCATCTC CCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors.
Science (New York, N.Y.)323(5919)1313-9(2009 Mar)
Schwenk J,Harmel N,Zolles G,Bildl W,Kulik A,Heimrich B,Chisaka O,Jonas P,Schulte U,Fakler B,Kl?cker N

Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, gamma-5.
Nature neuroscience12(3)277-85(2009 Mar)
Soto D,Coombs ID,Renzi M,Zonouzi M,Farrant M,Cull-Candy SG

AMPA receptor subunit-specific regulation by a distinct family of type II TARPs.
Neuron59(6)986-96(2008 Sep)
Kato AS,Siuda ER,Nisenbaum ES,Bredt DS

Calcium channel gamma subunits provide insights into the evolution of this gene family.
Gene280(1-2)37-48(2001 Dec)
Chu PJ,Robertson HM,Best PM