Cdc123 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cdc123
Entrez Gene ID	116656
Full Name	cell division cycle 123
Synonyms	D123
General protein information	Preferred Names cell division cycle 123 Names cell division cycle protein 123 homolog D123 gene product cell division cycle 123 homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q12.3
Summary	involved in temperature-sensitive G1-phase arrest in rat fibroblasts [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053877.3	NP_446329.1	cell division cycle protein 123 homolog

Pathways from BioSystems

Homologies

Homo sapiens (human)	CDC123	NP_006014.2
Danio rerio (zebrafish)	cdc123	NP_957015.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008049	XP_001689030.1
Pan troglodytes (chimpanzee)	CDC123	XP_001136775.1
Bos taurus (cattle)	CDC123	NP_001073743.1
Mus musculus (house mouse)	Cdc123	NP_598598.1
Eremothecium gossypii	AGOS_ADR081C	NP_984177.1
	CDC123	XP_001083055.1
Canis lupus familiaris (dog)	CDC123	XP_005617195.1
Rattus norvegicus (Norway rat)	Cdc123	NP_446329.1
Gallus gallus (chicken)	CDC123	XP_424021.2
Magnaporthe oryzae (rice blast fungus)	MGG_00369	XP_003718710.1
Schizosaccharomyces pombe (fission yeast)	SPAP27G11.03	NP_593407.1
Neurospora crassa	NCU06497	XP_957137.1
Arabidopsis thaliana (thale cress)	EDA35	NP_192453.1
Saccharomyces cerevisiae (baker's yeast)	CDC123	NP_013316.1
Kluyveromyces lactis	KLLA0F04972g	XP_455305.1
Eremothecium gossypii	AGOS_ADR082C	NP_984178.1
Xenopus tropicalis (tropical clawed frog)	cdc123	NP_001017200.2

Gene Ontology
Bibliography

Related articles in PubMed

Reversion of temperature-sensitive mutation by inhibition of proteasome-mediated degradation of mutated D123 protein.
Okuda A, Ohtsu M, Kimura G
Cell structure and function26(4)205-14(2001 Aug)

A visual intracellular classification strategy for uncharacterized human proteins.
Hoja MR, Wahlestedt C, H??g C
Experimental cell research259(1)239-46(2000 Aug)

Extensive degradation of mutant-type D123 protein is responsible for temperature-sensitive proliferation inhibition in 3Y1tsD123 cells.
Okuda A, Ohtsu M, Kimura G
Cell structure and function24(6)443-9(1999 Dec)

Expression study on D123 gene product: evidence for high positivity in testis.
Onisto M, Zeilante P, Scannapieco P, Pellati D, Pozza M, Caenazzo C, Negro A, Garbisa S
Experimental cell research242(2)451-9(1998 Aug)

An amino acid change in novel protein D123 is responsible for temperature-sensitive G1-phase arrest in a mutant of rat fibroblast line 3Y1.
Okuda A, Kimura G
Experimental cell research223(2)242-9(1996 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The D123 protein is unstable in the temperature-sensitive cell-cycle mutant of the rat 3Y1 fibroblast cell line.
Title: Reversion of temperature-sensitive mutation by inhibition of proteasome-mediated degradation of mutated D123 protein.

The following Cdc123 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdc123 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10930	NM_053877.3 Latest version!	Rattus norvegicus cell division cycle 123 (Cdc123), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cdc123 ( NM_053877.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446329.1 Rattus norvegicus cell division cycle 123 (Cdc123), mRNA.

Price & Availability↑

CloneID	ORa10930
Clone ID Related Accession (Same CDS sequence)	NM_053877.3
Accession Version	NM_053877.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	cell division cycle protein 123 homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC061527.1. On Aug 30, 2012 this sequence version replaced NM_053877.2. ##Evidence-Data-START## Transcript exon combination :: BC061527.1, FQ213222.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAAGAAGG AGCATGTTAG TCACTGTCAG TTCTCCGCGT GGTACCCACT CTTCCGAAGC 
CTTACCATCA AGAGTGTCAT CCTCCCGCTT CCTCAGAATG TGAAAGACTA TTTACTTGAC 
GACGGGACTC TGGTGGTCTC AGGAAGGGAA GACCCACCAA CATGCTCTCA GCCAGACAGT 
GGTGACGAAG CAGAGGAAAC ACAGTGGTCC GATGATGAGA GCACAGCCAC ACTTACGGCA 
CCCGAGTTTC CTGAGTTCAA TACTCAAGTC CAAGAAGCTA TCAATTCGCT GGGGGGCAGT 
GTCTTCCCTA AGCTTAACTG GAGTGCCCCA AGGGATGCAT ACTGGATAGC AATGAACAGT 
TCTCTGAAGT GTAAAAGCCT CAGTGACATC TTCCTGCTTT TCAAGAGTTC GGACTTCATC 
ACTCATGACT TCACACAGCC GTTTATTCAT TGTAATGATG ATTCTCCAGA TCCTTGTATA 
GAGTACGAGC TTGTTCTCCG AAAATGGTGT GAATTAATCC CTGGGGCTGA GTTCCGATGT 
TTTGTCAAGG AAAACAAGCT TATTGGTATT TCTCAGAGGG ACTACACGCA GTACTATGAT 
CATATCTCTA AGCAAAAAGA AGAAATTTGC AGATGCATTC AAGACTTTTT CAAGGAACAC 
CTGCAGTACA AATTCTTAGA TGAAGACTTT GTGTTTGATA TATACAGAGA CAGTAGGGGC 
AAGGTGTGGC TGATCGACTT TAACCCATTT GGGGAGGTCA CAGACTCTCT GCTGTTTACT 
TGGGAAGAGC TGACATCGGA GAACAATCTG CGAGGCGACG TCAGTGAGGC GGACGCTCTG 
GAGCAGGATT CTCCAGCCTT CCGTTGTACG AACAGTGAAG TCACGGTCCA GCCCAGCCCC 
TATCTGAGCT ACGGCCTGCC CAAGGACTTC GTAGACCTTT CCACCGGGGA AGATGCTCAC 
AAGCTCATAG ATTTTCTTAA GCTGAAAAGA AATCAGCAAG AGGACGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446329.1
CDS	42..1052
Translation	MKKEHVSHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPTCSQPDSGDEAEETQWSDDESTATLTAPEFPEFNTQVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKSLSDIFLLFKSSDFITHDFTQPFIHCNDDSPDPCIEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKEHLQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDSLLFTWEELTSENNLRGDVSEADALEQDSPAFRCTNSEVTVQPSPYLSYGLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD

Target ORF information:

RefSeq Version	NM_053877.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cell division cycle 123 (Cdc123), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053877.3

ORF Insert Sequence:

ATGAAGAAGG AGCATGTTAG TCACTGTCAG TTCTCCGCGT GGTACCCACT CTTCCGAAGC 
CTTACCATCA AGAGTGTCAT CCTCCCGCTT CCTCAGAATG TGAAAGACTA TTTACTTGAC 
GACGGGACTC TGGTGGTCTC AGGAAGGGAA GACCCACCAA CATGCTCTCA GCCAGACAGT 
GGTGACGAAG CAGAGGAAAC ACAGTGGTCC GATGATGAGA GCACAGCCAC ACTTACGGCA 
CCCGAGTTTC CTGAGTTCAA TACTCAAGTC CAAGAAGCTA TCAATTCGCT GGGGGGCAGT 
GTCTTCCCTA AGCTTAACTG GAGTGCCCCA AGGGATGCAT ACTGGATAGC AATGAACAGT 
TCTCTGAAGT GTAAAAGCCT CAGTGACATC TTCCTGCTTT TCAAGAGTTC GGACTTCATC 
ACTCATGACT TCACACAGCC GTTTATTCAT TGTAATGATG ATTCTCCAGA TCCTTGTATA 
GAGTACGAGC TTGTTCTCCG AAAATGGTGT GAATTAATCC CTGGGGCTGA GTTCCGATGT 
TTTGTCAAGG AAAACAAGCT TATTGGTATT TCTCAGAGGG ACTACACGCA GTACTATGAT 
CATATCTCTA AGCAAAAAGA AGAAATTTGC AGATGCATTC AAGACTTTTT CAAGGAACAC 
CTGCAGTACA AATTCTTAGA TGAAGACTTT GTGTTTGATA TATACAGAGA CAGTAGGGGC 
AAGGTGTGGC TGATCGACTT TAACCCATTT GGGGAGGTCA CAGACTCTCT GCTGTTTACT 
TGGGAAGAGC TGACATCGGA GAACAATCTG CGAGGCGACG TCAGTGAGGC GGACGCTCTG 
GAGCAGGATT CTCCAGCCTT CCGTTGTACG AACAGTGAAG TCACGGTCCA GCCCAGCCCC 
TATCTGAGCT ACGGCCTGCC CAAGGACTTC GTAGACCTTT CCACCGGGGA AGATGCTCAC 
AAGCTCATAG ATTTTCTTAA GCTGAAAAGA AATCAGCAAG AGGACGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Reversion of temperature-sensitive mutation by inhibition of proteasome-mediated degradation of mutated D123 protein.
Cell structure and function26(4)205-14(2001 Aug)
Okuda A,Ohtsu M,Kimura G

A visual intracellular classification strategy for uncharacterized human proteins.
Experimental cell research259(1)239-46(2000 Aug)
Hoja MR,Wahlestedt C,H??g C

Extensive degradation of mutant-type D123 protein is responsible for temperature-sensitive proliferation inhibition in 3Y1tsD123 cells.
Cell structure and function24(6)443-9(1999 Dec)
Okuda A,Ohtsu M,Kimura G

Expression study on D123 gene product: evidence for high positivity in testis.
Experimental cell research242(2)451-9(1998 Aug)
Onisto M,Zeilante P,Scannapieco P,Pellati D,Pozza M,Caenazzo C,Negro A,Garbisa S

An amino acid change in novel protein D123 is responsible for temperature-sensitive G1-phase arrest in a mutant of rat fibroblast line 3Y1.
Experimental cell research223(2)242-9(1996 Mar)
Okuda A,Kimura G