Exoc4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Exoc4
Entrez Gene ID	116654
Full Name	exocyst complex component 4
Synonyms	ALR,Sec8,Sec8l1
General protein information	Preferred Names exocyst complex component 4 Names exocyst complex component 4 SEC8-like 1 augmenter of liver regeneration (ALR) pseudogene exocyst complex component Sec8 rSec8 secretory protein SEC8
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q22
Summary	involved in Golgi-to-plasma membrane vesicle trafficking [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053875.1	NP_446327.1	exocyst complex component 4
XM_017592394.1	XP_017447883.1	exocyst complex component 4 isoform X1

Pathways from BioSystems

Homologies

	EXOC4	XP_001101640.2
Canis lupus familiaris (dog)	EXOC4	XP_539369.2
Mus musculus (house mouse)	Exoc4	NP_033174.2
Rattus norvegicus (Norway rat)	Exoc4	NP_446327.1
Pan troglodytes (chimpanzee)	EXOC4	XP_001139207.1
Drosophila melanogaster (fruit fly)	sec8	NP_730996.2
Xenopus tropicalis (tropical clawed frog)	exoc4	XP_002931915.2
Homo sapiens (human)	EXOC4	NP_068579.3
Gallus gallus (chicken)	EXOC4	NP_001186249.1
Bos taurus (cattle)	EXOC4	NP_001095677.1
Danio rerio (zebrafish)	exoc4	NP_001025305.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001694	XP_321399.5
Caenorhabditis elegans (roundworm)	sec-8	NP_492732.2

Gene Ontology
Bibliography

Related articles in PubMed

Arl13b and the exocyst interact synergistically in ciliogenesis.
Seixas C, Choi SY, Polgar N, Umberger NL, East MP, Zuo X, Moreiras H, Ghossoub R, Benmerah A, Kahn RA, Fogelgren B, Caspary T, Lipschutz JH, Barral DC
Molecular biology of the cell27(2)308-20(2016 Jan)

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.
Simicek M, Lievens S, Laga M, Guzenko D, Aushev VN, Kalev P, Baietti MF, Strelkov SV, Gevaert K, Tavernier J, Sablina AA
Nature cell biology15(10)1220-30(2013 Oct)

SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility.
Parrini MC, Sadou-Dubourgnoux A, Aoki K, Kunida K, Biondini M, Hatzoglou A, Poullet P, Formstecher E, Yeaman C, Matsuda M, Ross? C, Camonis J
Molecular cell42(5)650-61(2011 Jun)

The neural cell adhesion molecule promotes FGFR-dependent phosphorylation and membrane targeting of the exocyst complex to induce exocytosis in growth cones.
Chernyshova Y, Leshchyns'ka I, Hsu SC, Schachner M, Sytnyk V
The Journal of neuroscience : the official journal of the Society for Neuroscience31(10)3522-35(2011 Mar)

Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.
Oz?elik M, Cotter L, Jacob C, Pereira JA, Relvas JB, Suter U, Tricaud N
The Journal of neuroscience : the official journal of the Society for Neuroscience30(11)4120-31(2010 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

cytosolic PSD-95 interactor may function to regulate the ability of sec8 to bind to PSD-95
Title: Exocyst complex subunit sec8 binds to postsynaptic density protein-95 (PSD-95): a novel interaction regulated by cypin (cytosolic PSD-95 interactor).

The following Exoc4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Exoc4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10925	NM_053875.1 Latest version!	Rattus norvegicus exocyst complex component 4 (Exoc4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00
ORa60701	XM_017592394.1 Latest version!	Rattus norvegicus exocyst complex component 4 (Exoc4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Exoc4 ( NM_053875.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446327.1 Rattus norvegicus exocyst complex component 4 (Exoc4), mRNA.

Price & Availability↑

CloneID	ORa10925
Clone ID Related Accession (Same CDS sequence)	NM_053875.1
Accession Version	NM_053875.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2928bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	exocyst complex component 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from U32498.1 and FM107548.1. On or before Nov 22, 2008 this sequence version replaced XM_342655.3, XM_001063871.1, XM_001063828.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC 
TCGGGGCTGC TCATCTCGGT GATCAGGACT CTGTCTACCA GTGATGATGT TGAAGACCGA 
GAAAATGAGA AAGGTCGCCT TGAAGAAGCC TATGAGAAGT GTGACCGTGA CCTGGATGAA 
TTGATCGTTC AGCACTACAC AGAATTGACA ACAGCCATTC GCACATACCA GAGCATCACA 
GAACGCATCA CTAACTCCAG GAATAAAATC AAGCAGGTAA AAGAGAACCT GCTTTCCTGC 
AAGATGCTGT TGCATTGCAA ACGGGATGAG CTTCGTAAAC TATGGATTGA AGGAATTGAG 
CATAAGCATG TCCTGAACCT TCTGGATGAG ATTGAAAACA TCAAGCAAGT GCCTCAAAAG 
CTGGAACAGT GCATGGCCAG CAAGCACTAC CTCAGCGCCA CGGACATGCT GGTGTCAGCA 
GTGGAGTCTC TGGAGGGTCC GCTGCTCCAG GTGGAAGGAC TCAGTGACCT CAGGCTGGAA 
CTTCACAGCA AGAAGATGAA CCTGCACTTG GTTCTCATAG AGGAACTGCA CCGACATCTG 
TACATCAAAT CCACTAGCCG GGTTGTACAG CGTAACAAGG AAAAAGGGAA GATGAGTTCT 
CATGGCAAAG ATGCTTCTCC TGGTCCTCTG ATTGATGTTT CAAACATCTC TACTCCACGC 
AAATTCCTTG ATGCCACTCA ATATTCTGCT GCTGGAAGCT CAAGTGTGAG GGAGATGAAC 
CTGCAGGACA TCAAAGAGGA CTTGGACTGT GATCCTGAGG AGAACAGCAC TCTTTTCATG 
GGAATTCTTA TTCAGGGGCT GGCCAGACTG AAGAAGATCC CTGAGACCGT TAAAGCCATT 
AAAGAGCGTT TGGAGCAGGA GCTAAAGCAG ATTGTGAAGA GGTCAACCAC CCAGGTGGCA 
GACAGTGCCT ATCAGAGGGG AGAGAGCCTC ACTGTGGACA ACCAGCCAAG GTTACTTCTA 
GAACTGCTGG AACTGTTGTT TGATAAGTTT AATGCTGTAG CCAGTGCACA TTCTATAGTC 
CTGGGGTACC TTCAGGACTC TGTGGGGACC CAGCCAACAC AGCAGGAAGA GATCAAATTA 
TACGATATGG CAGATGTGTG GGTGAAGATC CAGGATGTGC TGCAGATGCT GTTGACTGAA 
TACTTGGATA TGAAGAACAC ACGTACTGCG TCAGAGCCGT CAGCTCAACT AAGCTATGCC 
AGTACTGGAC GAGAGTTCGC AGCCTTTTTT GCCAAGAAGA AACCACAAAG GCCAAAGAAT 
TCTCTTTTCA AGTTTGAATC ATCCTCCCAT GCTATCAGTA TGAGCGCCTA TCTCCGAGAA 
CAGAGAAGGG AGCTGTACAG TCGGAGTGGA GAACTTCAAG GAGGTCCTGA TGACAACTTA 
ATTGAAGGTG GAGGAACAAA ATTTGTCTGC AAACCTGGAG CCAGAAATAT TACCGTCATA 
TTCCATCCAC TGCTGAGATT TATTCAGGAG ATTGAGCATG CCCTGGGACT TGGCCCTGCC 
AAACAGTGTC TCCTTCGAGA GTTTCTCACT ATATATATCA AGAACATCTT CCTTAATCAG 
GTCTTGACTG AGATCAACAA GGAGATCGAA GGTGTCACCA AAACCTCAGA CCCCTTGAAG 
ATCCTAGCTA ATGCAGACAC CATGAAGGTT CTGGGCGTGC AGAGGCCTCT TCTACAGAGC 
ACCATCATCG TGGAGAAGAC AGTACAAGAC CTCATGAACC TGATGCATGA CTTGAGTGCA 
TATTCAGATC AGTTCCTCAA CATGGTGTGT GTGAAGCTAC AGGAATACAA GGACACATGC 
TCCACAGCCT ACAGAGGCAT TGTCCAATCA GAAGAGAAAC TTGTCATCAG TGCATCTTGG 
GCAAAAGATG ATGATATCAG CAGACTCTTG AAATCACTGC CGAACTGGAC TAACATGGCT 
CAGCCCAAAC AGCTAAGGCC TAAGAGAGAG GAGGAGGAAG ACTTCATAAG GGCAGCCTTT 
GGCAAGGAGT CTGAGGTTCT GATTGGAAAC CTTGGTGACA AACTCATTCC TCCACAAGAT 
ATTCTCCGTG ACGTCAGTGA CCTCAAAGCC TTGGCCAACA TGCATGAAAG CCTGGAATGG 
CTGGCAGGCC GAACAAAGTC AGCTTTCTCC AGCCTTTCTG CATCCCAGAT GCTTTCCCCT 
GCTCAAGAGA GCCACGTAAA CATGGACCTT CCTCCAGTGT CTGAACAGAT CATGCAGACG 
CTGAGTGAAC TTGCCAAGTC CTTCCAGGAC ATGGCTGACC GCTGCTTGCT CGTCTTGCAT 
CTGGAAGTGA GAGTTCATTG TTTCCACTAT CTCATCCCTC TGGCAAAGGA GGGGAACTAT 
GCCATTGTGG CCAATGTGGA AAGCATGGAT TATGACCCTT TAGTGGTCAA GCTCAACAAA 
GACATCAGTG CCATGGAAGA GGCCATGAGC GCCAGCCTCC AGCAACACAA GTTCCAGTAC 
ATCTTCGAAG GTCTGGGACA CCTCATCTCC TGTATCCTCA TTAATGGGGC TCAGTACTTC 
CGGCGCATCA GTGAGTCTGG CATCAAGAAA ATGTGTAGAA ACATTTTTGT TCTTCAGCAG 
AATTTGACCA ACATCACCAT GTCACGGGAG GCAGACTTGG ACTTTGCAAG ACAGTACTAC 
GAGATGCTGT ACAACACTGC TGATGAGCTC CTGAACCTGG TGGTGGACCA GGGTGTGAAA 
TACACAGAGC TAGAGTACAT CCATGCCCTG ACCCTGCTGC ACCGAAGCCA GACTGGCGTG 
GGGGACCAGA CCACCCAGAA CACCAGGCTG CAGAGACTCA AGGAGATCAT CTGTGAGCAG 
GCTGCCATCA AGCAAGCCAC CAAGGACAAG AAAATAACCA CTGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446327.1
CDS	1..2928
Translation	MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIEELHRHLYIKSTSRVVQRNKEKGKMSSHGKDASPGPLIDVSNISTPRKFLDATQYSAAGSSSVREMNLQDIKEDLDCDPEENSTLFMGILIQGLARLKKIPETVKAIKERLEQELKQIVKRSTTQVADSAYQRGESLTVDNQPRLLLELLELLFDKFNAVASAHSIVLGYLQDSVGTQPTQQEEIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLIEGGGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAKQCLLREFLTIYIKNIFLNQVLTEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTVQDLMNLMHDLSAYSDQFLNMVCVKLQEYKDTCSTAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWTNMAQPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLAGRTKSAFSSLSASQMLSPAQESHVNMDLPPVSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAMEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGDQTTQNTRLQRLKEIICEQAAIKQATKDKKITTV

Target ORF information:

RefSeq Version	NM_053875.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus exocyst complex component 4 (Exoc4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053875.1

ORF Insert Sequence:

ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC 
TCGGGGCTGC TCATCTCGGT GATCAGGACT CTGTCTACCA GTGATGATGT TGAAGACCGA 
GAAAATGAGA AAGGTCGCCT TGAAGAAGCC TATGAGAAGT GTGACCGTGA CCTGGATGAA 
TTGATCGTTC AGCACTACAC AGAATTGACA ACAGCCATTC GCACATACCA GAGCATCACA 
GAACGCATCA CTAACTCCAG GAATAAAATC AAGCAGGTAA AAGAGAACCT GCTTTCCTGC 
AAGATGCTGT TGCATTGCAA ACGGGATGAG CTTCGTAAAC TATGGATTGA AGGAATTGAG 
CATAAGCATG TCCTGAACCT TCTGGATGAG ATTGAAAACA TCAAGCAAGT GCCTCAAAAG 
CTGGAACAGT GCATGGCCAG CAAGCACTAC CTCAGCGCCA CGGACATGCT GGTGTCAGCA 
GTGGAGTCTC TGGAGGGTCC GCTGCTCCAG GTGGAAGGAC TCAGTGACCT CAGGCTGGAA 
CTTCACAGCA AGAAGATGAA CCTGCACTTG GTTCTCATAG AGGAACTGCA CCGACATCTG 
TACATCAAAT CCACTAGCCG GGTTGTACAG CGTAACAAGG AAAAAGGGAA GATGAGTTCT 
CATGGCAAAG ATGCTTCTCC TGGTCCTCTG ATTGATGTTT CAAACATCTC TACTCCACGC 
AAATTCCTTG ATGCCACTCA ATATTCTGCT GCTGGAAGCT CAAGTGTGAG GGAGATGAAC 
CTGCAGGACA TCAAAGAGGA CTTGGACTGT GATCCTGAGG AGAACAGCAC TCTTTTCATG 
GGAATTCTTA TTCAGGGGCT GGCCAGACTG AAGAAGATCC CTGAGACCGT TAAAGCCATT 
AAAGAGCGTT TGGAGCAGGA GCTAAAGCAG ATTGTGAAGA GGTCAACCAC CCAGGTGGCA 
GACAGTGCCT ATCAGAGGGG AGAGAGCCTC ACTGTGGACA ACCAGCCAAG GTTACTTCTA 
GAACTGCTGG AACTGTTGTT TGATAAGTTT AATGCTGTAG CCAGTGCACA TTCTATAGTC 
CTGGGGTACC TTCAGGACTC TGTGGGGACC CAGCCAACAC AGCAGGAAGA GATCAAATTA 
TACGATATGG CAGATGTGTG GGTGAAGATC CAGGATGTGC TGCAGATGCT GTTGACTGAA 
TACTTGGATA TGAAGAACAC ACGTACTGCG TCAGAGCCGT CAGCTCAACT AAGCTATGCC 
AGTACTGGAC GAGAGTTCGC AGCCTTTTTT GCCAAGAAGA AACCACAAAG GCCAAAGAAT 
TCTCTTTTCA AGTTTGAATC ATCCTCCCAT GCTATCAGTA TGAGCGCCTA TCTCCGAGAA 
CAGAGAAGGG AGCTGTACAG TCGGAGTGGA GAACTTCAAG GAGGTCCTGA TGACAACTTA 
ATTGAAGGTG GAGGAACAAA ATTTGTCTGC AAACCTGGAG CCAGAAATAT TACCGTCATA 
TTCCATCCAC TGCTGAGATT TATTCAGGAG ATTGAGCATG CCCTGGGACT TGGCCCTGCC 
AAACAGTGTC TCCTTCGAGA GTTTCTCACT ATATATATCA AGAACATCTT CCTTAATCAG 
GTCTTGACTG AGATCAACAA GGAGATCGAA GGTGTCACCA AAACCTCAGA CCCCTTGAAG 
ATCCTAGCTA ATGCAGACAC CATGAAGGTT CTGGGCGTGC AGAGGCCTCT TCTACAGAGC 
ACCATCATCG TGGAGAAGAC AGTACAAGAC CTCATGAACC TGATGCATGA CTTGAGTGCA 
TATTCAGATC AGTTCCTCAA CATGGTGTGT GTGAAGCTAC AGGAATACAA GGACACATGC 
TCCACAGCCT ACAGAGGCAT TGTCCAATCA GAAGAGAAAC TTGTCATCAG TGCATCTTGG 
GCAAAAGATG ATGATATCAG CAGACTCTTG AAATCACTGC CGAACTGGAC TAACATGGCT 
CAGCCCAAAC AGCTAAGGCC TAAGAGAGAG GAGGAGGAAG ACTTCATAAG GGCAGCCTTT 
GGCAAGGAGT CTGAGGTTCT GATTGGAAAC CTTGGTGACA AACTCATTCC TCCACAAGAT 
ATTCTCCGTG ACGTCAGTGA CCTCAAAGCC TTGGCCAACA TGCATGAAAG CCTGGAATGG 
CTGGCAGGCC GAACAAAGTC AGCTTTCTCC AGCCTTTCTG CATCCCAGAT GCTTTCCCCT 
GCTCAAGAGA GCCACGTAAA CATGGACCTT CCTCCAGTGT CTGAACAGAT CATGCAGACG 
CTGAGTGAAC TTGCCAAGTC CTTCCAGGAC ATGGCTGACC GCTGCTTGCT CGTCTTGCAT 
CTGGAAGTGA GAGTTCATTG TTTCCACTAT CTCATCCCTC TGGCAAAGGA GGGGAACTAT 
GCCATTGTGG CCAATGTGGA AAGCATGGAT TATGACCCTT TAGTGGTCAA GCTCAACAAA 
GACATCAGTG CCATGGAAGA GGCCATGAGC GCCAGCCTCC AGCAACACAA GTTCCAGTAC 
ATCTTCGAAG GTCTGGGACA CCTCATCTCC TGTATCCTCA TTAATGGGGC TCAGTACTTC 
CGGCGCATCA GTGAGTCTGG CATCAAGAAA ATGTGTAGAA ACATTTTTGT TCTTCAGCAG 
AATTTGACCA ACATCACCAT GTCACGGGAG GCAGACTTGG ACTTTGCAAG ACAGTACTAC 
GAGATGCTGT ACAACACTGC TGATGAGCTC CTGAACCTGG TGGTGGACCA GGGTGTGAAA 
TACACAGAGC TAGAGTACAT CCATGCCCTG ACCCTGCTGC ACCGAAGCCA GACTGGCGTG 
GGGGACCAGA CCACCCAGAA CACCAGGCTG CAGAGACTCA AGGAGATCAT CTGTGAGCAG 
GCTGCCATCA AGCAAGCCAC CAAGGACAAG AAAATAACCA CTGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Exoc4 ( XM_017592394.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447883.1 Rattus norvegicus exocyst complex component 4 (Exoc4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa60701
Clone ID Related Accession (Same CDS sequence)	XM_017592394.1
Accession Version	XM_017592394.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2928bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	exocyst complex component 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) and transcript sequence (U32498.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 175 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END##

ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC 
TCGGGGCTGC TCATCTCGGT GATCAGGACT CTGTCTACCA GTGATGATGT TGAAGACCGA 
GAAAATGAGA AAGGTCGCCT TGAAGAAGCC TATGAGAAGT GTGACCGTGA CCTGGATGAA 
TTGATCGTTC AGCACTACAC AGAATTGACA ACAGCCATTC GCACATACCA GAGCATCACA 
GAACGCATCA CTAACTCCAG GAATAAAATC AAGCAGGTAA AAGAGAACCT GCTTTCCTGC 
AAGATGCTGT TGCATTGCAA ACGGGATGAG CTTCGTAAAC TATGGATTGA AGGAATTGAG 
CATAAGCATG TCCTGAACCT TCTGGATGAG ATTGAAAACA TCAAGCAAGT GCCTCAAAAG 
CTGGAACAGT GCATGGCCAG CAAGCACTAC CTCAGCGCCA CGGACATGCT GGTGTCAGCA 
GTGGAGTCTC TGGAGGGTCC GCTGCTCCAG GTGGAAGGAC TCAGTGACCT CAGGCTGGAA 
CTTCACAGCA AGAAGATGAA CCTGCACTTG GTTCTCATAG AGGAACTGCA CCGACATCTG 
TACATCAAAT CCACTAGCCG GGTTGTACAG CGTAACAAGG AAAAAGGGAA GATGAGTTCT 
CATGGCAAAG ATGCTTCTCC TGGTCCTCTG ATTGATGTTT CAAACATCTC TACTCCACGC 
AAATTCCTTG ATGCCACTCA ATATTCTGCT GCTGGAAGCT CAAGTGTGAG GGAGATGAAC 
CTGCAGGACA TCAAAGAGGA CTTGGACTGT GATCCTGAGG AGAACAGCAC TCTTTTCATG 
GGAATTCTTA TTCAGGGGCT GGCCAGACTG AAGAAGATCC CTGAGACCGT TAAAGCCATT 
AAAGAGCGTT TGGAGCAGGA GCTAAAGCAG ATTGTGAAGA GGTCAACCAC CCAGGTGGCA 
GACAGTGCCT ATCAGAGGGG AGAGAGCCTC ACTGTGGACA ACCAGCCAAG GTTACTTCTA 
GAACTGCTGG AACTGTTGTT TGATAAGTTT AATGCTGTAG CCAGTGCACA TTCTATAGTC 
CTGGGGTACC TTCAGGACTC TGTGGGGACC CAGCCAACAC AGCAGGAAGA GATCAAATTA 
TACGATATGG CAGATGTGTG GGTGAAGATC CAGGATGTGC TGCAGATGCT GTTGACTGAA 
TACTTGGATA TGAAGAACAC ACGTACTGCG TCAGAGCCGT CAGCTCAACT AAGCTATGCC 
AGTACTGGAC GAGAGTTCGC AGCCTTTTTT GCCAAGAAGA AACCACAAAG GCCAAAGAAT 
TCTCTTTTCA AGTTTGAATC ATCCTCCCAT GCTATCAGTA TGAGCGCCTA TCTCCGAGAA 
CAGAGAAGGG AGCTGTACAG TCGGAGTGGA GAACTTCAAG GAGGTCCTGA TGACAACTTA 
ATTGAAGGTG GAGGAACAAA ATTTGTCTGC AAACCTGGAG CCAGAAATAT TACCGTCATA 
TTCCATCCAC TGCTGAGATT TATTCAGGAG ATTGAGCATG CCCTGGGACT TGGCCCTGCC 
AAACAGTGTC CTCTTCGAGA GTTTCTCACT ATATATATCA AGAACATCTT CCTTAATCAG 
GTCTTGACTG AGATCAACAA GGAGATCGAA GGTGTCACCA AAACCTCAGA CCCCTTGAAG 
ATCCTAGCTA ATGCAGACAC CATGAAGGTT CTGGGCGTGC AGAGGCCTCT TCTACAGAGC 
ACCATCATCG TGGAGAAGAC AGTACAAGAC CTCATGAACC TGATGCATGA CTTGAGTGCA 
TATTCAGATC AGTTCCTCAA CATGGTGTGT GTGAAGCTAC AGGAATACAA GGACACATGC 
TCCACAGCCT ACAGAGGCAT TGTCCAATCA GAAGAGAAAC TTGTCATCAG TGCATCTTGG 
GCAAAAGATG ATGATATCAG CAGACTCTTG AAATCACTGC CGAACTGGAC TAACATGGCT 
CAGCCCAAAC AGCTAAGGCC TAAGAGAGAG GAGGAGGAAG ACTTCATAAG GGCAGCCTTT 
GGCAAGGAGT CTGAGGTTCT GATTGGAAAC CTTGGTGACA AACTCATTCC TCCACAAGAT 
ATTCTCCGTG ACGTCAGTGA CCTCAAAGCC TTGGCCAACA TGCATGAAAG CCTGGAATGG 
CTGGCAGGCC GAACAAAGTC AGCTTTCTCC AGCCTTTCTG CATCCCAGAT GCTTTCCCCT 
GCTCAAGAGA GCCACGTAAA CATGGACCTT CCTCCAGTGT CTGAACAGAT CATGCAGACG 
CTGAGTGAAC TTGCCAAGTC CTTCCAGGAC ATGGCTGACC GCTGCTTGCT CGTCTTGCAT 
CTGGAAGTGA GAGTTCATTG TTTCCACTAT CTCATCCCTC TGGCAAAGGA GGGGAACTAT 
GCCATTGTGG CCAATGTGGA AAGCATGGAT TATGACCCTT TAGTGGTCAA GCTCAACAAA 
GACATCAGTG CCATGGAAGA GGCCATGAGC GCCAGCCTCC AGCAACACAA GTTCCAGTAC 
ATCTTCGAAG GTCTGGGACA CCTCATCTCC TGTATCCTCA TTAATGGGGC TCAGTACTTC 
CGGCGCATCA GTGAGTCTGG CATCAAGAAA ATGTGTAGAA ACATTTTTGT TCTTCAGCAG 
AATTTGACCA ACATCACCAT GTCACGGGAG GCAGACTTGG ACTTTGCAAG ACAGTACTAC 
GAGATGCTGT ACAACACTGC TGATGAGCTC CTGAACCTGG TGGTGGACCA GGGTGTGAAA 
TACACAGAGC TAGAGTACAT CCATGCCCTG ACCCTGCTGC ACCGAAGCCA GACTGGCGTG 
GGGGACCAGA CCACCCAGAA CACCAGGCTG CAGAGACTCA AGGAGATCAT CTGTGAGCAG 
GCTGCCATCA AGCAAGCCAC CAAGGACAAG AAAATAACCA CTGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447883.1
CDS	70..2997
Translation	MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDELIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIEHKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLELHSKKMNLHLVLIEELHRHLYIKSTSRVVQRNKEKGKMSSHGKDASPGPLIDVSNISTPRKFLDATQYSAAGSSSVREMNLQDIKEDLDCDPEENSTLFMGILIQGLARLKKIPETVKAIKERLEQELKQIVKRSTTQVADSAYQRGESLTVDNQPRLLLELLELLFDKFNAVASAHSIVLGYLQDSVGTQPTQQEEIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYASTGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLIEGGGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAKQCPLREFLTIYIKNIFLNQVLTEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTVQDLMNLMHDLSAYSDQFLNMVCVKLQEYKDTCSTAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWTNMAQPKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWLAGRTKSAFSSLSASQMLSPAQESHVNMDLPPVSEQIMQTLSELAKSFQDMADRCLLVLHLEVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAMEEAMSASLQQHKFQYIFEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYEMLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGDQTTQNTRLQRLKEIICEQAAIKQATKDKKITTV

Target ORF information:

RefSeq Version	XM_017592394.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus exocyst complex component 4 (Exoc4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017592394.1

ORF Insert Sequence:

ATGGCGGCAG AAGCAGCTGG TGGGAAATAC AGGAGCACAG TCAGCAAAAG CAAAGACCCC 
TCGGGGCTGC TCATCTCGGT GATCAGGACT CTGTCTACCA GTGATGATGT TGAAGACCGA 
GAAAATGAGA AAGGTCGCCT TGAAGAAGCC TATGAGAAGT GTGACCGTGA CCTGGATGAA 
TTGATCGTTC AGCACTACAC AGAATTGACA ACAGCCATTC GCACATACCA GAGCATCACA 
GAACGCATCA CTAACTCCAG GAATAAAATC AAGCAGGTAA AAGAGAACCT GCTTTCCTGC 
AAGATGCTGT TGCATTGCAA ACGGGATGAG CTTCGTAAAC TATGGATTGA AGGAATTGAG 
CATAAGCATG TCCTGAACCT TCTGGATGAG ATTGAAAACA TCAAGCAAGT GCCTCAAAAG 
CTGGAACAGT GCATGGCCAG CAAGCACTAC CTCAGCGCCA CGGACATGCT GGTGTCAGCA 
GTGGAGTCTC TGGAGGGTCC GCTGCTCCAG GTGGAAGGAC TCAGTGACCT CAGGCTGGAA 
CTTCACAGCA AGAAGATGAA CCTGCACTTG GTTCTCATAG AGGAACTGCA CCGACATCTG 
TACATCAAAT CCACTAGCCG GGTTGTACAG CGTAACAAGG AAAAAGGGAA GATGAGTTCT 
CATGGCAAAG ATGCTTCTCC TGGTCCTCTG ATTGATGTTT CAAACATCTC TACTCCACGC 
AAATTCCTTG ATGCCACTCA ATATTCTGCT GCTGGAAGCT CAAGTGTGAG GGAGATGAAC 
CTGCAGGACA TCAAAGAGGA CTTGGACTGT GATCCTGAGG AGAACAGCAC TCTTTTCATG 
GGAATTCTTA TTCAGGGGCT GGCCAGACTG AAGAAGATCC CTGAGACCGT TAAAGCCATT 
AAAGAGCGTT TGGAGCAGGA GCTAAAGCAG ATTGTGAAGA GGTCAACCAC CCAGGTGGCA 
GACAGTGCCT ATCAGAGGGG AGAGAGCCTC ACTGTGGACA ACCAGCCAAG GTTACTTCTA 
GAACTGCTGG AACTGTTGTT TGATAAGTTT AATGCTGTAG CCAGTGCACA TTCTATAGTC 
CTGGGGTACC TTCAGGACTC TGTGGGGACC CAGCCAACAC AGCAGGAAGA GATCAAATTA 
TACGATATGG CAGATGTGTG GGTGAAGATC CAGGATGTGC TGCAGATGCT GTTGACTGAA 
TACTTGGATA TGAAGAACAC ACGTACTGCG TCAGAGCCGT CAGCTCAACT AAGCTATGCC 
AGTACTGGAC GAGAGTTCGC AGCCTTTTTT GCCAAGAAGA AACCACAAAG GCCAAAGAAT 
TCTCTTTTCA AGTTTGAATC ATCCTCCCAT GCTATCAGTA TGAGCGCCTA TCTCCGAGAA 
CAGAGAAGGG AGCTGTACAG TCGGAGTGGA GAACTTCAAG GAGGTCCTGA TGACAACTTA 
ATTGAAGGTG GAGGAACAAA ATTTGTCTGC AAACCTGGAG CCAGAAATAT TACCGTCATA 
TTCCATCCAC TGCTGAGATT TATTCAGGAG ATTGAGCATG CCCTGGGACT TGGCCCTGCC 
AAACAGTGTC CTCTTCGAGA GTTTCTCACT ATATATATCA AGAACATCTT CCTTAATCAG 
GTCTTGACTG AGATCAACAA GGAGATCGAA GGTGTCACCA AAACCTCAGA CCCCTTGAAG 
ATCCTAGCTA ATGCAGACAC CATGAAGGTT CTGGGCGTGC AGAGGCCTCT TCTACAGAGC 
ACCATCATCG TGGAGAAGAC AGTACAAGAC CTCATGAACC TGATGCATGA CTTGAGTGCA 
TATTCAGATC AGTTCCTCAA CATGGTGTGT GTGAAGCTAC AGGAATACAA GGACACATGC 
TCCACAGCCT ACAGAGGCAT TGTCCAATCA GAAGAGAAAC TTGTCATCAG TGCATCTTGG 
GCAAAAGATG ATGATATCAG CAGACTCTTG AAATCACTGC CGAACTGGAC TAACATGGCT 
CAGCCCAAAC AGCTAAGGCC TAAGAGAGAG GAGGAGGAAG ACTTCATAAG GGCAGCCTTT 
GGCAAGGAGT CTGAGGTTCT GATTGGAAAC CTTGGTGACA AACTCATTCC TCCACAAGAT 
ATTCTCCGTG ACGTCAGTGA CCTCAAAGCC TTGGCCAACA TGCATGAAAG CCTGGAATGG 
CTGGCAGGCC GAACAAAGTC AGCTTTCTCC AGCCTTTCTG CATCCCAGAT GCTTTCCCCT 
GCTCAAGAGA GCCACGTAAA CATGGACCTT CCTCCAGTGT CTGAACAGAT CATGCAGACG 
CTGAGTGAAC TTGCCAAGTC CTTCCAGGAC ATGGCTGACC GCTGCTTGCT CGTCTTGCAT 
CTGGAAGTGA GAGTTCATTG TTTCCACTAT CTCATCCCTC TGGCAAAGGA GGGGAACTAT 
GCCATTGTGG CCAATGTGGA AAGCATGGAT TATGACCCTT TAGTGGTCAA GCTCAACAAA 
GACATCAGTG CCATGGAAGA GGCCATGAGC GCCAGCCTCC AGCAACACAA GTTCCAGTAC 
ATCTTCGAAG GTCTGGGACA CCTCATCTCC TGTATCCTCA TTAATGGGGC TCAGTACTTC 
CGGCGCATCA GTGAGTCTGG CATCAAGAAA ATGTGTAGAA ACATTTTTGT TCTTCAGCAG 
AATTTGACCA ACATCACCAT GTCACGGGAG GCAGACTTGG ACTTTGCAAG ACAGTACTAC 
GAGATGCTGT ACAACACTGC TGATGAGCTC CTGAACCTGG TGGTGGACCA GGGTGTGAAA 
TACACAGAGC TAGAGTACAT CCATGCCCTG ACCCTGCTGC ACCGAAGCCA GACTGGCGTG 
GGGGACCAGA CCACCCAGAA CACCAGGCTG CAGAGACTCA AGGAGATCAT CTGTGAGCAG 
GCTGCCATCA AGCAAGCCAC CAAGGACAAG AAAATAACCA CTGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Arl13b and the exocyst interact synergistically in ciliogenesis.
Molecular biology of the cell27(2)308-20(2016 Jan)
Seixas C,Choi SY,Polgar N,Umberger NL,East MP,Zuo X,Moreiras H,Ghossoub R,Benmerah A,Kahn RA,Fogelgren B,Caspary T,Lipschutz JH,Barral DC

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.
Nature cell biology15(10)1220-30(2013 Oct)
Simicek M,Lievens S,Laga M,Guzenko D,Aushev VN,Kalev P,Baietti MF,Strelkov SV,Gevaert K,Tavernier J,Sablina AA

SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility.
Molecular cell42(5)650-61(2011 Jun)
Parrini MC,Sadou-Dubourgnoux A,Aoki K,Kunida K,Biondini M,Hatzoglou A,Poullet P,Formstecher E,Yeaman C,Matsuda M,Ross? C,Camonis J

The neural cell adhesion molecule promotes FGFR-dependent phosphorylation and membrane targeting of the exocyst complex to induce exocytosis in growth cones.
The Journal of neuroscience : the official journal of the Society for Neuroscience31(10)3522-35(2011 Mar)
Chernyshova Y,Leshchyns'ka I,Hsu SC,Schachner M,Sytnyk V

Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.
The Journal of neuroscience : the official journal of the Society for Neuroscience30(11)4120-31(2010 Mar)
Oz?elik M,Cotter L,Jacob C,Pereira JA,Relvas JB,Suter U,Tricaud N

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Exoc4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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