Nup107 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nup107
Entrez Gene ID	116555
Full Name	nucleoporin 107
General protein information	Preferred Names nucleoporin 107 Names nuclear pore complex protein Nup107 107 kDa nucleoporin nucleoporin Nup107 p105
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q22
Summary	nuclear pore complex protein [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053830.2	NP_446282.2	nuclear pore complex protein Nup107

Pathways from BioSystems

Homologies

Homo sapiens (human)	NUP107	NP_065134.1
Pan troglodytes (chimpanzee)	NUP107	XP_001153762.1
Mus musculus (house mouse)	Nup107	NP_598771.1
Canis lupus familiaris (dog)	NUP107	XP_531670.3
Drosophila melanogaster (fruit fly)	Nup107	NP_609446.1
	NUP107	XP_001117201.1
Danio rerio (zebrafish)	nup107	NP_001025338.1
Bos taurus (cattle)	NUP107	XP_002687439.1
Gallus gallus (chicken)	NUP107	XP_004937621.1
Rattus norvegicus (Norway rat)	Nup107	NP_446282.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001685	XP_001238474.3
Xenopus tropicalis (tropical clawed frog)	nup107	XP_004912994.1

Gene Ontology
Bibliography

Related articles in PubMed

A mutation in the nucleoporin-107 gene causes XX gonadal dysgenesis.
Weinberg-Shukron A, Renbaum P, Kalifa R, Zeligson S, Ben-Neriah Z, Dreifuss A, Abu-Rayyan A, Maatuk N, Fardian N, Rekler D, Kanaan M, Samson AO, Levy-Lahad E, Gerlitz O, Zangen D
The Journal of clinical investigation125(11)4295-304(2015 Nov)

Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome.
Miyake N, Tsukaguchi H, Koshimizu E, Shono A, Matsunaga S, Shiina M, Mimura Y, Imamura S, Hirose T, Okudela K, Nozu K, Akioka Y, Hattori M, Yoshikawa N, Kitamura A, Cheong HI, Kagami S, Yamashita M, Fujita A, Miyatake S, Tsurusaki Y, Nakashima M, Saitsu H, Ohashi K, Imamoto N, Ryo A, Ogata K, Iijima K, Matsumoto N
American journal of human genetics97(4)555-66(2015 Oct)

Regulation of mRNA trafficking by nuclear pore complexes.
Bonnet A, Palancade B
Genes5(3)767-91(2014 Sep)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nup107 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nup107 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10794	NM_053830.2 Latest version!	Rattus norvegicus nucleoporin 107 (Nup107), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$545.30 $779.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nup107 ( NM_053830.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446282.2 Rattus norvegicus nucleoporin 107 (Nup107), mRNA.

Price & Availability↑

CloneID	ORa10794
Clone ID Related Accession (Same CDS sequence)	NM_053830.2
Accession Version	NM_053830.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2778bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	nuclear pore complex protein Nup107
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB733157.1, AABR07057213.1, CB775175.1, CV120917.1, EV764995.1, CB792533.1, AABR07057210.1, C07146.1, CK844566.1 and BQ191246.1. On Oct 11, 2007 this sequence version replaced NM_053830.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L31840.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACAGGA GTGGCTTCGG GGGAATGTCA TCCCCTGTGA TCCGAGACCC AGAGGTTACG 
AGGACTGCAC GGAAGCATAG TGCTCACAAA AGAGTTTTAA TTCAGGCCAA CCAAGATGAA 
AATTTTGGTA CTACTACACC AAGAAGCCAG ATTATTCCTC GAACTCCAAG CTCATTTCGA 
CAACCTTTTA CTCCACCAAG CCGAAGTTTA CTAAGACACC CAGATATATC CTACATTTTT 
GGGACGGAAG GGAGGTCTCC CCGGCATATA CAGTCTTCTG GGTATTTGGG AAATCTTTCC 
ATGGTGACTA ACCTTGATGA CAGCAACTGG GCAGCTGCAT TCTCATCCCA GCGTTTAGGG 
TTCTACACAA ACACGGAGCA CCATAGTATG ACTGAGGACA TAAACCTAAG TACTGTCATG 
CTACGGGAGG ATGACCCTGG AGAGGCTGCA TCCATGAGTA TGTTCTCTGA TTTCCTGCAG 
TCTTTCTTGA AGCACTCTTC AACCACAGTC TTTGATCTTG TAGAAGAGTA TGAAAATATT 
TGTGCTAGTC AGGTGAACAT CCTGAGTAAA ATCGTGAGCC GAGCAACGCC TGGACTGCAG 
AAGTTCTCCA AGACAGCCAG CATGCTCTGG CTTCTCCAGC AGGAGATGGT CACGTGGAGG 
CTGCTTGCCT CTTTGTATAG AGACAGAATA CAGTCTTCAT TAGAAGAGGA AAATATGTTT 
GCAATTGCTG GTATCAATGC CAGTGAGAAG ACGGTTGTGG AAGCGCTGTT TCAGAGGGAC 
ACGCTGGTCC GACAGAGCCA GTTGGTGGTA GATTGGCTAG AGAGCATTGC CAAAGATGAA 
ATTGGAGATT TCTCAGACAA TATTGAGTTT TATGCAAAAT CAGTATATTG GGAAAATACA 
CTCCACTCCT TAAAACAGCG GCAGCTGCTG TCTTATATAG GAAGTACCCG TCCTCTTGTC 
ACTGAGCTGG ACCCAGATGC TCCCATTAGA CAGAAAATGC CGCTGGATGA TCTGGACAGA 
GAAGATGAAG TCAGACTGCT GAAGTACCTC TTCACTCTAA TCCGTGCTGG GATGACCGAG 
GAGGCACAGA GGCTCTGTAA ACGGTGCGGG CAAGCATGGA GAGCTGCAAC CCTGGAAGGA 
TGGAAGCTGC ACCACGACCC CAACGTGAAT GGAGGGACAG AGCTAGAGCC TGTCGAAGGG 
AATCCATATA GACGGATCTG GAAGATTAGT TGCTGGAGAA TGGCTGAAGA TGAACTTTTT 
AATAAATACG AAAGAGCGAT TTATGCAGCA CTCAGTGGGA ATCTCAAGCA GCTCCTTCCG 
GTCTGTGACA CCTGGGAAGA CACAGTGTGG GCCTATTTCC GGGTGATGGT GGACAGCCTG 
GTGGAGCAGG AGATTCGCAC CTCAGTCATG ACCCTAGATG AAACTGAGGA GCTCCCTCGG 
GAGTACATGG AAGCGAATTG GACCTTAGAA AAAGTTTTTG AAGAGCTTCA AGCCACTGAT 
AAGAAGAGAG TTCTGGAAGA GAATCAAGAA CATTACCATG TAGTCCAGAA ATTCCTTATC 
CTGGGAGACA TTGATGGTTT GATGGATGAA TTTAGCAAAT GGCTGTCCAA GAGCAGAAGC 
AGTCTACCTG GACACCTCCT CCGTTTTATG ACTCACCTCA TTCTGTTTTT CCGCACCCTG 
GGACTGCAGA CCAAAGAAGA AGTTTCCATT GAAGTTCTAA AGACGTATAT ACAGCTGTTA 
ATCAATGAGA AGCACACAAA CCTCATAGCG TTCTATACCT GTCATCTGCC TCAAGACCTT 
GCGGTTGCCC AATACGCCTT GTTTTTGGAG GGTGTTACGG AGTGTGAGCA GCGGCACCAG 
TGCCTGGAGC TGGCTAAGGA GGCAGATTTG GATGTTGCGA CTATAACAAA AACTGTAGTT 
GAAAATATTC GGAAGAAAGA TAATGGTGAA TTCAGTCACC ATGACCTGGC TCCATCCCTG 
GATACTGCCA CTACTGAGGA GGACCGTTTG AAGATCGATG TGATTGACTG GCTGGTGTTT 
GACCCAGCGC AGAGAGCCGA AGCCCTGAGA CAAGGCAACG CCATCATGAG GAAGTTCTTA 
GCATTAAAGA AACATGAAGC TGCAAAAGAA GTGTTTGTGA AAATTCCTCA GGATTCCATC 
GCAGAAATCT ATAATCAGTG GGAGGAGCAA GGCATGGAGA GCCCTCTTCC TGCCGAGGAT 
GATAACGCTA TCCGAGAGCA CTTGTGTATC AGAGCTTATC TGGAAGCCCA TGAAACCTTC 
AATGAGTGGT TTAAACATAT GAATTCGGCT CCTCAGAAAC CTACACTGCT GTCCCAGGCG 
ACTTTTACAG AGAAAGTGGC TCACGAGCAC AAAGAAAAGA AGTACGAGAT GGATCATAAT 
ATTTGGAAAG GACATTTGGA TGCTCTAACT GCTGATGTGA AGGAGAAAAT GTACAACGTC 
TTATTGTTTG TTGATGGAGG ATGGATGGTG GATGTCAGAG AGGACGCTGA GGAAGACCCG 
GAACGAGCTC ATCAGATGGT TTTGCTGAGA AAGCTCTGTC TCCCCATGCT GTGCTTCCTG 
CTTCACACCA TACTGCACAG CACCGGGCAA TACCAGGAGT GCCTGCAGCT GGCCGACATG 
GTGTCCTCTG AGCGCCACAA GCTCTATCTG GTATTTTCTA AGGAAGAACT AAGGAAACTG 
CTGCAGAAGT TAAGGGAGTC CTCGCTGATG CTCCTAGACC AGGGGCTTGA CCCGCTCGGC 
TATGAAATCC AGTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446282.2
CDS	69..2846
Translation	MDRSGFGGMSSPVIRDPEVTRTARKHSAHKRVLIQANQDENFGTTTPRSQIIPRTPSSFRQPFTPPSRSLLRHPDISYIFGTEGRSPRHIQSSGYLGNLSMVTNLDDSNWAAAFSSQRLGFYTNTEHHSMTEDINLSTVMLREDDPGEAASMSMFSDFLQSFLKHSSTTVFDLVEEYENICASQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSSLEEENMFAIAGINASEKTVVEALFQRDTLVRQSQLVVDWLESIAKDEIGDFSDNIEFYAKSVYWENTLHSLKQRQLLSYIGSTRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLHHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNKYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIRTSVMTLDETEELPREYMEANWTLEKVFEELQATDKKRVLEENQEHYHVVQKFLILGDIDGLMDEFSKWLSKSRSSLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLINEKHTNLIAFYTCHLPQDLAVAQYALFLEGVTECEQRHQCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPSLDTATTEEDRLKIDVIDWLVFDPAQRAEALRQGNAIMRKFLALKKHEAAKEVFVKIPQDSIAEIYNQWEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSAPQKPTLLSQATFTEKVAHEHKEKKYEMDHNIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAEEDPERAHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQS

Target ORF information:

RefSeq Version	NM_053830.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nucleoporin 107 (Nup107), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053830.2

ORF Insert Sequence:

ATGGACAGGA GTGGCTTCGG GGGAATGTCA TCCCCTGTGA TCCGAGACCC AGAGGTTACG 
AGGACTGCAC GGAAGCATAG TGCTCACAAA AGAGTTTTAA TTCAGGCCAA CCAAGATGAA 
AATTTTGGTA CTACTACACC AAGAAGCCAG ATTATTCCTC GAACTCCAAG CTCATTTCGA 
CAACCTTTTA CTCCACCAAG CCGAAGTTTA CTAAGACACC CAGATATATC CTACATTTTT 
GGGACGGAAG GGAGGTCTCC CCGGCATATA CAGTCTTCTG GGTATTTGGG AAATCTTTCC 
ATGGTGACTA ACCTTGATGA CAGCAACTGG GCAGCTGCAT TCTCATCCCA GCGTTTAGGG 
TTCTACACAA ACACGGAGCA CCATAGTATG ACTGAGGACA TAAACCTAAG TACTGTCATG 
CTACGGGAGG ATGACCCTGG AGAGGCTGCA TCCATGAGTA TGTTCTCTGA TTTCCTGCAG 
TCTTTCTTGA AGCACTCTTC AACCACAGTC TTTGATCTTG TAGAAGAGTA TGAAAATATT 
TGTGCTAGTC AGGTGAACAT CCTGAGTAAA ATCGTGAGCC GAGCAACGCC TGGACTGCAG 
AAGTTCTCCA AGACAGCCAG CATGCTCTGG CTTCTCCAGC AGGAGATGGT CACGTGGAGG 
CTGCTTGCCT CTTTGTATAG AGACAGAATA CAGTCTTCAT TAGAAGAGGA AAATATGTTT 
GCAATTGCTG GTATCAATGC CAGTGAGAAG ACGGTTGTGG AAGCGCTGTT TCAGAGGGAC 
ACGCTGGTCC GACAGAGCCA GTTGGTGGTA GATTGGCTAG AGAGCATTGC CAAAGATGAA 
ATTGGAGATT TCTCAGACAA TATTGAGTTT TATGCAAAAT CAGTATATTG GGAAAATACA 
CTCCACTCCT TAAAACAGCG GCAGCTGCTG TCTTATATAG GAAGTACCCG TCCTCTTGTC 
ACTGAGCTGG ACCCAGATGC TCCCATTAGA CAGAAAATGC CGCTGGATGA TCTGGACAGA 
GAAGATGAAG TCAGACTGCT GAAGTACCTC TTCACTCTAA TCCGTGCTGG GATGACCGAG 
GAGGCACAGA GGCTCTGTAA ACGGTGCGGG CAAGCATGGA GAGCTGCAAC CCTGGAAGGA 
TGGAAGCTGC ACCACGACCC CAACGTGAAT GGAGGGACAG AGCTAGAGCC TGTCGAAGGG 
AATCCATATA GACGGATCTG GAAGATTAGT TGCTGGAGAA TGGCTGAAGA TGAACTTTTT 
AATAAATACG AAAGAGCGAT TTATGCAGCA CTCAGTGGGA ATCTCAAGCA GCTCCTTCCG 
GTCTGTGACA CCTGGGAAGA CACAGTGTGG GCCTATTTCC GGGTGATGGT GGACAGCCTG 
GTGGAGCAGG AGATTCGCAC CTCAGTCATG ACCCTAGATG AAACTGAGGA GCTCCCTCGG 
GAGTACATGG AAGCGAATTG GACCTTAGAA AAAGTTTTTG AAGAGCTTCA AGCCACTGAT 
AAGAAGAGAG TTCTGGAAGA GAATCAAGAA CATTACCATG TAGTCCAGAA ATTCCTTATC 
CTGGGAGACA TTGATGGTTT GATGGATGAA TTTAGCAAAT GGCTGTCCAA GAGCAGAAGC 
AGTCTACCTG GACACCTCCT CCGTTTTATG ACTCACCTCA TTCTGTTTTT CCGCACCCTG 
GGACTGCAGA CCAAAGAAGA AGTTTCCATT GAAGTTCTAA AGACGTATAT ACAGCTGTTA 
ATCAATGAGA AGCACACAAA CCTCATAGCG TTCTATACCT GTCATCTGCC TCAAGACCTT 
GCGGTTGCCC AATACGCCTT GTTTTTGGAG GGTGTTACGG AGTGTGAGCA GCGGCACCAG 
TGCCTGGAGC TGGCTAAGGA GGCAGATTTG GATGTTGCGA CTATAACAAA AACTGTAGTT 
GAAAATATTC GGAAGAAAGA TAATGGTGAA TTCAGTCACC ATGACCTGGC TCCATCCCTG 
GATACTGCCA CTACTGAGGA GGACCGTTTG AAGATCGATG TGATTGACTG GCTGGTGTTT 
GACCCAGCGC AGAGAGCCGA AGCCCTGAGA CAAGGCAACG CCATCATGAG GAAGTTCTTA 
GCATTAAAGA AACATGAAGC TGCAAAAGAA GTGTTTGTGA AAATTCCTCA GGATTCCATC 
GCAGAAATCT ATAATCAGTG GGAGGAGCAA GGCATGGAGA GCCCTCTTCC TGCCGAGGAT 
GATAACGCTA TCCGAGAGCA CTTGTGTATC AGAGCTTATC TGGAAGCCCA TGAAACCTTC 
AATGAGTGGT TTAAACATAT GAATTCGGCT CCTCAGAAAC CTACACTGCT GTCCCAGGCG 
ACTTTTACAG AGAAAGTGGC TCACGAGCAC AAAGAAAAGA AGTACGAGAT GGATCATAAT 
ATTTGGAAAG GACATTTGGA TGCTCTAACT GCTGATGTGA AGGAGAAAAT GTACAACGTC 
TTATTGTTTG TTGATGGAGG ATGGATGGTG GATGTCAGAG AGGACGCTGA GGAAGACCCG 
GAACGAGCTC ATCAGATGGT TTTGCTGAGA AAGCTCTGTC TCCCCATGCT GTGCTTCCTG 
CTTCACACCA TACTGCACAG CACCGGGCAA TACCAGGAGT GCCTGCAGCT GGCCGACATG 
GTGTCCTCTG AGCGCCACAA GCTCTATCTG GTATTTTCTA AGGAAGAACT AAGGAAACTG 
CTGCAGAAGT TAAGGGAGTC CTCGCTGATG CTCCTAGACC AGGGGCTTGA CCCGCTCGGC 
TATGAAATCC AGTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A mutation in the nucleoporin-107 gene causes XX gonadal dysgenesis.
The Journal of clinical investigation125(11)4295-304(2015 Nov)
Weinberg-Shukron A,Renbaum P,Kalifa R,Zeligson S,Ben-Neriah Z,Dreifuss A,Abu-Rayyan A,Maatuk N,Fardian N,Rekler D,Kanaan M,Samson AO,Levy-Lahad E,Gerlitz O,Zangen D

Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome.
American journal of human genetics97(4)555-66(2015 Oct)
Miyake N,Tsukaguchi H,Koshimizu E,Shono A,Matsunaga S,Shiina M,Mimura Y,Imamura S,Hirose T,Okudela K,Nozu K,Akioka Y,Hattori M,Yoshikawa N,Kitamura A,Cheong HI,Kagami S,Yamashita M,Fujita A,Miyatake S,Tsurusaki Y,Nakashima M,Saitsu H,Ohashi K,Imamoto N,Ryo A,Ogata K,Iijima K,Matsumoto N

Regulation of mRNA trafficking by nuclear pore complexes.
Genes5(3)767-91(2014 Sep)
Bonnet A,Palancade B

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA