Gripap1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gripap1
Entrez Gene ID	116493
Full Name	GRIP1 associated protein 1
Synonyms	Grasp1
General protein information	Preferred Names GRIP1 associated protein 1 Names GRIP1-associated protein 1 GRASP-1 GRIP-associated protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq12
Summary	a neuronal rasGEF that may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053807.2	NP_446259.1	GRIP1-associated protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	GRIPAP1	NP_064522.3
Canis lupus familiaris (dog)	GRIPAP1	XP_548991.2
Mus musculus (house mouse)	Gripap1	NP_997553.1
Rattus norvegicus (Norway rat)	Gripap1	NP_446259.1
	GRIPAP1	XP_001105181.2
Bos taurus (cattle)	GRIPAP1	NP_001180035.1
Danio rerio (zebrafish)	gripap1	NP_001116792.1

Gene Ontology
Bibliography

Related articles in PubMed

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
Bastos-Amador P, Royo F, Gonzalez E, Conde-Vancells J, Palomo-Diez L, Borras FE, Falcon-Perez JM
Journal of proteomics75(12)3574-84(2012 Jun)

Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes.
Hoogenraad CC, Popa I, Futai K, Martinez-Sanchez E, Sanchez-Martinez E, Wulf PS, van Vlijmen T, Dortland BR, Oorschot V, Govers R, Monti M, Heck AJ, Sheng M, Klumperman J, Rehmann H, Jaarsma D, Kapitein LC, van der Sluijs P
PLoS biology8(1)e1000283(2010 Jan)

GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex.
Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL
Neuron26(3)603-17(2000 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Gripap1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gripap1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10703	NM_053807.2 Latest version!	Rattus norvegicus GRIP1 associated protein 1 (Gripap1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gripap1 ( NM_053807.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446259.1 Rattus norvegicus GRIP1 associated protein 1 (Gripap1), mRNA.

Price & Availability↑

CloneID	ORa10703
Clone ID Related Accession (Same CDS sequence)	NM_053807.2
Accession Version	NM_053807.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2514bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Rattus norvegicus(Norway rat)
Product	GRIP1-associated protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC130624.4 and BQ780554.1. On Apr 7, 2017 this sequence version replaced NM_053807.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGCAAG CTCTGTCTGA AGAGGAGTTT CAACGGATGC AGACACAGCT CCTGGAACTC 
CGGACAAATA ACTACCAGCT TTCAGATGAA CTCCGGAAGA ATGGTGTTGA ACTTTCCAGT 
CTTCGACAGA AGGTCGCCTA CCTGGATAAG GAATTCAGTA AAGCTCAAAA GGCACTAAGC 
AAGAGCAAGA AAGCTCAGGA AGTGGAGGTA CTGCTGAGTG AAAAAGAGAT GCTGCAGGCA 
AAGCTGCACA GCCAGGAGGA GGACTTCCGT TTGCAGAACA GTACACTTAT GGCCGAGTTC 
AGCAAGCTCT GCAGCCAGCT GGAGCAGCTG GAGCTGGAGA ACCGACAACT CAAGGAAGGG 
GTTCCTGGAG CAGCTGGACC ACATGTGGAC GGGGAGCTGC TGAGGCTGCA GGCAGAGAAC 
ACAGCCTTGC AGAAGAACAT GGCAGCACTG CAGGAGCGCT ATGGGAAAGA GGCTGTGAGG 
CCCTCCGCTG TCAGTGAGGG CCAAGGAGAT CCACCAGGAG ATGTACTCCC CATTTCCTTG 
TCTCCCATGC CATTGGCAGA AGTGGAGCTG AAGTGGGAAA TGGAGAGAGA AGAAAAAAAG 
TTGCTTTGGG AACAGCTACA AGGCTTAGAG AGCTCAAAGC AAGCTGAAAC CTCCAGACTC 
CAGGAGGAAC TTGCTAAGCT CTCTGAGAAA TTGAAAAAGA AACAGGAAAG TTTTTGCCGT 
CTACAGACAG AGAAGGAAAC ACTGTTTAAT GATAGCAGGA ACAAAATTGA AGAATTGCAA 
CAACGGAAGG AAGCTGATCT GAAAGCCCAG TTGGCTCGCA CCCAAAAACT ACAGCAGGAA 
CTTGAGGCTG CCAATCAGAG CTTGGCAGAG CTAAGAGATC AGCGGCAGGG GGAGCGTCTG 
GAGCATGCAG CAGCACTGCG GGCCCTACAA GATCAGGTGT CCAGCCAGAG TGCAGATGCG 
CAGGAACAAG TGGAAGGGCT ATTGGCTGAG AACAATGCCT TGAGGACTAG CTTGGCCGCT 
CTGGAGCAGA TCCAGACAGC AAAGACACAG GAACTGAATA TGCTTCGGGA ACAGAACACT 
GAACTGGCAG CCGAGTTAAA GCATCGACAG GCTGACTATG AAGAGCTTAT GGGACAGAAA 
GACGACCTCA ACTCCCAGCT CCAGGAGTCG TTAAGGGCCA ATAGCCGGCT GCTGGAACAA 
CTACAAGAAA TGGGGCAGGA GAAGGAGCAG CTGATCCAGG ATCTCCAGGA AGCTCGGAAG 
AGTGCTGAGA AAAGGAAGGT CATGCTGGAT GAGCTAGCCA TGGAGACACT GCAGGAGAAG 
TCCCAGCACA AAGAAGAATT GGGGGCTGTC CGGTTACGGC ATGAGAAGGA GATGCTGGGG 
GTGCGAGCCC GTTATGAGCG GGAGCTTCGA GAACTGCATG AGGACAAGAA ACGGCAGGAG 
GAGGAGCTCC GGGGGCAGAT TCGTGAGGAG AAGGCTCGAA CAAGGGAATT AGAAAATCTT 
CAGCACACAG TGGAAGAACT TCAGGCTCAG GTACACTCCA TGGATGGAGC CAAGGGCTGG 
TTTGAACGGC GCCTGAAGGA AGCTGAGGAA TCCTTACTGC AGCAAGAGCA GGAACAGGAG 
GAAACCCTCA AGCAGTGCCG GGAGCAGCAC GCTGCCGAGC TGAAGGGCAA GGAGGAAGAG 
CTTCAGAATG TTCGAGATCA GCTCCAGCAG GCCCAGGAAG AGCGAGATGG CCATGTGAAG 
ACCATCAGCA ACCTGAAGCA GGAGGTAAAG GACACAGTGG ACGGGCAGCG GATCCTGGAA 
AAGAAAGGCA GTGCTGTGCT CAAAGACCTT AAGAGGCAGC TGCACCTAGA GCGGAAGCGG 
GCTGATAAGC TGCAGGAACG GCTGCAGGAG ATCCTGACTA ACAGCAAGAG CCGCACAGGC 
CTTGAGGAGC TGGTTCTCTC TGAGATGAAC TCACCAAGCA GGACCCAGAC AGGGGACAGC 
AGTAGCGTCT CCTCCTTCAG CTACCGGGAG ATCTTGAAGG AAAAGGAGAG TTCAGCCATC 
CCAGCCAGGT CTCTATCCAG CAGTCCTCAG GCGCAGCCCC CTCGGCCAGC AGAGCTGTCA 
GATGAGGAAG TGGCTGAGCT GTTTCAGAGG CTGGCCGAGA CACAGCAGGA GAAATGGATG 
CTGGAGGAGA AGGTGAAACA CCTGGAGGTG AGCAGCGCCT CGATGGCGGA AGACCTCTGT 
CGGAAAAGTG CCATCATTGA GACCTACGTC ATGGACAGCC GGATTGATGT GTCTGTGGCA 
GCAGGCCACA CAGACCGAAG TGGGCTGGGC AGTGTCCTGA GAGACCTAGT GAAGCCCGGC 
GATGAGAACC TTCGGGAAAT GAACAAGAAG CTGCAGAACA TGTTGGAGGA GCAACTCACC 
AAGAACATGC ACTTGCACAA GGACATGGAA GTTCTATCCC AAGAAATTGT GCGGCTCAGC 
AAGGAATGCG TGGGGTCCCC TGACCCAGAC CTAGAACCTG GAGAAGCCAA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446259.1
CDS	20..2533
Translation	MAQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQKALSKSKKAQEVEVLLSEKEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQLEQLELENRQLKEGVPGAAGPHVDGELLRLQAENTALQKNMAALQERYGKEAVRPSAVSEGQGDPPGDVLPISLSPMPLAEVELKWEMEREEKKLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSSQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQNTELAAELKHRQADYEELMGQKDDLNSQLQESLRANSRLLEQLQEMGQEKEQLIQDLQEARKSAEKRKVMLDELAMETLQEKSQHKEELGAVRLRHEKEMLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQAQVHSMDGAKGWFERRLKEAEESLLQQEQEQEETLKQCREQHAAELKGKEEELQNVRDQLQQAQEERDGHVKTISNLKQEVKDTVDGQRILEKKGSAVLKDLKRQLHLERKRADKLQERLQEILTNSKSRTGLEELVLSEMNSPSRTQTGDSSSVSSFSYREILKEKESSAIPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGSPDPDLEPGEAN

Target ORF information:

RefSeq Version	NM_053807.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus GRIP1 associated protein 1 (Gripap1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053807.2

ORF Insert Sequence:

ATGGCGCAAG CTCTGTCTGA AGAGGAGTTT CAACGGATGC AGACACAGCT CCTGGAACTC 
CGGACAAATA ACTACCAGCT TTCAGATGAA CTCCGGAAGA ATGGTGTTGA ACTTTCCAGT 
CTTCGACAGA AGGTCGCCTA CCTGGATAAG GAATTCAGTA AAGCTCAAAA GGCACTAAGC 
AAGAGCAAGA AAGCTCAGGA AGTGGAGGTA CTGCTGAGTG AAAAAGAGAT GCTGCAGGCA 
AAGCTGCACA GCCAGGAGGA GGACTTCCGT TTGCAGAACA GTACACTTAT GGCCGAGTTC 
AGCAAGCTCT GCAGCCAGCT GGAGCAGCTG GAGCTGGAGA ACCGACAACT CAAGGAAGGG 
GTTCCTGGAG CAGCTGGACC ACATGTGGAC GGGGAGCTGC TGAGGCTGCA GGCAGAGAAC 
ACAGCCTTGC AGAAGAACAT GGCAGCACTG CAGGAGCGCT ATGGGAAAGA GGCTGTGAGG 
CCCTCCGCTG TCAGTGAGGG CCAAGGAGAT CCACCAGGAG ATGTACTCCC CATTTCCTTG 
TCTCCCATGC CATTGGCAGA AGTGGAGCTG AAGTGGGAAA TGGAGAGAGA AGAAAAAAAG 
TTGCTTTGGG AACAGCTACA AGGCTTAGAG AGCTCAAAGC AAGCTGAAAC CTCCAGACTC 
CAGGAGGAAC TTGCTAAGCT CTCTGAGAAA TTGAAAAAGA AACAGGAAAG TTTTTGCCGT 
CTACAGACAG AGAAGGAAAC ACTGTTTAAT GATAGCAGGA ACAAAATTGA AGAATTGCAA 
CAACGGAAGG AAGCTGATCT GAAAGCCCAG TTGGCTCGCA CCCAAAAACT ACAGCAGGAA 
CTTGAGGCTG CCAATCAGAG CTTGGCAGAG CTAAGAGATC AGCGGCAGGG GGAGCGTCTG 
GAGCATGCAG CAGCACTGCG GGCCCTACAA GATCAGGTGT CCAGCCAGAG TGCAGATGCG 
CAGGAACAAG TGGAAGGGCT ATTGGCTGAG AACAATGCCT TGAGGACTAG CTTGGCCGCT 
CTGGAGCAGA TCCAGACAGC AAAGACACAG GAACTGAATA TGCTTCGGGA ACAGAACACT 
GAACTGGCAG CCGAGTTAAA GCATCGACAG GCTGACTATG AAGAGCTTAT GGGACAGAAA 
GACGACCTCA ACTCCCAGCT CCAGGAGTCG TTAAGGGCCA ATAGCCGGCT GCTGGAACAA 
CTACAAGAAA TGGGGCAGGA GAAGGAGCAG CTGATCCAGG ATCTCCAGGA AGCTCGGAAG 
AGTGCTGAGA AAAGGAAGGT CATGCTGGAT GAGCTAGCCA TGGAGACACT GCAGGAGAAG 
TCCCAGCACA AAGAAGAATT GGGGGCTGTC CGGTTACGGC ATGAGAAGGA GATGCTGGGG 
GTGCGAGCCC GTTATGAGCG GGAGCTTCGA GAACTGCATG AGGACAAGAA ACGGCAGGAG 
GAGGAGCTCC GGGGGCAGAT TCGTGAGGAG AAGGCTCGAA CAAGGGAATT AGAAAATCTT 
CAGCACACAG TGGAAGAACT TCAGGCTCAG GTACACTCCA TGGATGGAGC CAAGGGCTGG 
TTTGAACGGC GCCTGAAGGA AGCTGAGGAA TCCTTACTGC AGCAAGAGCA GGAACAGGAG 
GAAACCCTCA AGCAGTGCCG GGAGCAGCAC GCTGCCGAGC TGAAGGGCAA GGAGGAAGAG 
CTTCAGAATG TTCGAGATCA GCTCCAGCAG GCCCAGGAAG AGCGAGATGG CCATGTGAAG 
ACCATCAGCA ACCTGAAGCA GGAGGTAAAG GACACAGTGG ACGGGCAGCG GATCCTGGAA 
AAGAAAGGCA GTGCTGTGCT CAAAGACCTT AAGAGGCAGC TGCACCTAGA GCGGAAGCGG 
GCTGATAAGC TGCAGGAACG GCTGCAGGAG ATCCTGACTA ACAGCAAGAG CCGCACAGGC 
CTTGAGGAGC TGGTTCTCTC TGAGATGAAC TCACCAAGCA GGACCCAGAC AGGGGACAGC 
AGTAGCGTCT CCTCCTTCAG CTACCGGGAG ATCTTGAAGG AAAAGGAGAG TTCAGCCATC 
CCAGCCAGGT CTCTATCCAG CAGTCCTCAG GCGCAGCCCC CTCGGCCAGC AGAGCTGTCA 
GATGAGGAAG TGGCTGAGCT GTTTCAGAGG CTGGCCGAGA CACAGCAGGA GAAATGGATG 
CTGGAGGAGA AGGTGAAACA CCTGGAGGTG AGCAGCGCCT CGATGGCGGA AGACCTCTGT 
CGGAAAAGTG CCATCATTGA GACCTACGTC ATGGACAGCC GGATTGATGT GTCTGTGGCA 
GCAGGCCACA CAGACCGAAG TGGGCTGGGC AGTGTCCTGA GAGACCTAGT GAAGCCCGGC 
GATGAGAACC TTCGGGAAAT GAACAAGAAG CTGCAGAACA TGTTGGAGGA GCAACTCACC 
AAGAACATGC ACTTGCACAA GGACATGGAA GTTCTATCCC AAGAAATTGT GCGGCTCAGC 
AAGGAATGCG TGGGGTCCCC TGACCCAGAC CTAGAACCTG GAGAAGCCAA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
Journal of proteomics75(12)3574-84(2012 Jun)
Bastos-Amador P,Royo F,Gonzalez E,Conde-Vancells J,Palomo-Diez L,Borras FE,Falcon-Perez JM

Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes.
PLoS biology8(1)e1000283(2010 Jan)
Hoogenraad CC,Popa I,Futai K,Martinez-Sanchez E,Sanchez-Martinez E,Wulf PS,van Vlijmen T,Dortland BR,Oorschot V,Govers R,Monti M,Heck AJ,Sheng M,Klumperman J,Rehmann H,Jaarsma D,Kapitein LC,van der Sluijs P

GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex.
Neuron26(3)603-17(2000 Jun)
Ye B,Liao D,Zhang X,Zhang P,Dong H,Huganir RL