Ube2n cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ube2n
Entrez Gene ID	93765
Full Name	ubiquitin-conjugating enzyme E2N
Synonyms	1500026J17Rik,AL022654,BB101821,UBC13
General protein information	Preferred Names ubiquitin-conjugating enzyme E2N Names ubiquitin-conjugating enzyme E2 N E2 ubiquitin-conjugating enzyme N bendless-like ubiquitin-conjugating enzyme ubiquitin carrier protein N ubiquitin-protein ligase N
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 C2

mRNA and Protein(s)

mRNA	Protein	Name
XM_006514344.4	XP_006514407.1	ubiquitin-conjugating enzyme E2 N isoform X1
XM_006514344.3	XP_006514407.1	ubiquitin-conjugating enzyme E2 N isoform X1
NM_080560.3	NP_542127.1	ubiquitin-conjugating enzyme E2 N

Pathways from BioSystems

Homologies

Homo sapiens (human)	UBE2N	NP_003339.1
Pan troglodytes (chimpanzee)	UBE2N	XP_003952317.1
	UBE2N	XP_001105664.2
Gallus gallus (chicken)	UBE2N	NP_001012828.1
Canis lupus familiaris (dog)	UBE2N	NP_001239060.1
Bos taurus (cattle)	UBE2N	NP_001069726.1
Rattus norvegicus (Norway rat)	Ube2n	NP_446380.1
Danio rerio (zebrafish)	ube2na	NP_998651.1
Drosophila melanogaster (fruit fly)	CG3473	NP_609715.1
Mus musculus (house mouse)	Ube2n	NP_542127.1
Danio rerio (zebrafish)	ube2nb	NP_956636.1
Caenorhabditis elegans (roundworm)	ubc-13	NP_500272.2
Arabidopsis thaliana (thale cress)	UBC36	NP_001185017.1
Xenopus tropicalis (tropical clawed frog)	ube2n	NP_989375.1

Gene Ontology
Bibliography

Related articles in PubMed

RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain.
Valnegri P, Huang J, Yamada T, Yang Y, Mejia LA, Cho HY, Oldenborg A, Bonni A
Nature communications8(1)1271(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GPS2 is required for restricting the activation of TLR and BCR signaling pathways and the AKT/FOXO1 pathway in immune cells based on direct inhibition of Ubc13 enzymatic activity
Title: Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development.

RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
Title: RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.

Overexpressing UBE2N increases the aggregation of mutant huntingtin, and reducing UBE2N attenuates huntingtin aggregation in cellular and mouse models of Huntington's disease.
Title: Aged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin.

STAT3 restrains RANKL- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.
Title: STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.

Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells.
Title: Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells.

The following Ube2n gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ube2n cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu23043	NM_080560.3 Latest version!	Mus musculus ubiquitin-conjugating enzyme E2N (Ube2n), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu44970	XM_006514344.4 Latest version!	Mus musculus ubiquitin-conjugating enzyme E2N (Ube2n), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu44970	XM_006514344.3	Mus musculus ubiquitin-conjugating enzyme E2N (Ube2n), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ube2n ( NM_080560.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_542127.1 Mus musculus ubiquitin-conjugating enzyme E2N (Ube2n), mRNA.

Price & Availability↑

CloneID	OMu23043
Clone ID Related Accession (Same CDS sequence)	NM_080560.3
Accession Version	NM_080560.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Mus musculus(house mouse)
Product	ubiquitin-conjugating enzyme E2 N
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC159135.11. On Nov 17, 2006 this sequence version replaced NM_080560.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC067069.1, SRR1660819.49493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGGC TGCCCCGCAG GATCATCAAG GAAACCCAGC GTTTGCTGGC AGAACCAGTT 
CCTGGCATTA AAGCAGAACC AGATGAGAGC AACGCCCGTT ATTTTCATGT GGTCATTGCT 
GGCCCCCAGG ATTCCCCCTT TGAGGGAGGG ACTTTTAAAC TTGAACTATT CCTTCCAGAA 
GAATACCCAA TGGCAGCACC TAAAGTACGT TTCATGACCA AAATTTATCA TCCTAATGTA 
GACAAGTTGG GAAGAATATG TTTAGATATT TTGAAAGATA AGTGGTCCCC AGCACTGCAG 
ATCCGCACAG TTCTGCTATC AATCCAGGCT TTGTTAAGTG CTCCTAATCC AGATGATCCA 
TTAGCAAATG ATGTAGCCGA GCAATGGAAG ACCAACGAAG CCCAAGCCAT AGAAACAGCG 
AGAGCATGGA CTAGGCTATA TGCCATGAAC AATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542127.1
CDS	47..505
Translation	MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI

Target ORF information:

RefSeq Version	NM_080560.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ubiquitin-conjugating enzyme E2N (Ube2n), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080560.3

ORF Insert Sequence:

ATGGCCGGGC TGCCCCGCAG GATCATCAAG GAAACCCAGC GTTTGCTGGC AGAACCAGTT 
CCTGGCATTA AAGCAGAACC AGATGAGAGC AACGCCCGTT ATTTTCATGT GGTCATTGCT 
GGCCCCCAGG ATTCCCCCTT TGAGGGAGGG ACTTTTAAAC TTGAACTATT CCTTCCAGAA 
GAATACCCAA TGGCAGCACC TAAAGTACGT TTCATGACCA AAATTTATCA TCCTAATGTA 
GACAAGTTGG GAAGAATATG TTTAGATATT TTGAAAGATA AGTGGTCCCC AGCACTGCAG 
ATCCGCACAG TTCTGCTATC AATCCAGGCT TTGTTAAGTG CTCCTAATCC AGATGATCCA 
TTAGCAAATG ATGTAGCCGA GCAATGGAAG ACCAACGAAG CCCAAGCCAT AGAAACAGCG 
AGAGCATGGA CTAGGCTATA TGCCATGAAC AATATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ube2n ( XM_006514344.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006514407.1 Mus musculus ubiquitin-conjugating enzyme E2N (Ube2n), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu44970
Clone ID Related Accession (Same CDS sequence)	XM_006514344.4 , XM_006514344.3
Accession Version	XM_006514344.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ubiquitin-conjugating enzyme E2 N isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006514344.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCGAC CCCGAGAGCC GGGCGGGGCC GCGGGCCGGG AGAGGCCGCT CCGGGAGGGC 
CACGGGGTTC TGCCGGCGAC AGCACAGGAA ACCCAGCGTT TGCTGGCAGA ACCAGTTCCT 
GGCATTAAAG CAGAACCAGA TGAGAGCAAC GCCCGTTATT TTCATGTGGT CATTGCTGGC 
CCCCAGGATT CCCCCTTTGA GGGAGGGACT TTTAAACTTG AACTATTCCT TCCAGAAGAA 
TACCCAATGG CAGCACCTAA AGTACGTTTC ATGACCAAAA TTTATCATCC TAATGTAGAC 
AAGTTGGGAA GAATATGTTT AGATATTTTG AAAGATAAGT GGTCCCCAGC ACTGCAGATC 
CGCACAGTTC TGCTATCAAT CCAGGCTTTG TTAAGTGCTC CTAATCCAGA TGATCCATTA 
GCAAATGATG TAGCCGAGCA ATGGAAGACC AACGAAGCCC AAGCCATAGA AACAGCGAGA 
GCATGGACTA GGCTATATGC CATGAACAAT ATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006514407.1
CDS	201..716
Translation	MDRPREPGGAAGRERPLREGHGVLPATAQETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI

Target ORF information:

RefSeq Version	XM_006514344.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus ubiquitin-conjugating enzyme E2N (Ube2n), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006514344.4

ORF Insert Sequence:

ATGGACCGAC CCCGAGAGCC GGGCGGGGCC GCGGGCCGGG AGAGGCCGCT CCGGGAGGGC 
CACGGGGTTC TGCCGGCGAC AGCACAGGAA ACCCAGCGTT TGCTGGCAGA ACCAGTTCCT 
GGCATTAAAG CAGAACCAGA TGAGAGCAAC GCCCGTTATT TTCATGTGGT CATTGCTGGC 
CCCCAGGATT CCCCCTTTGA GGGAGGGACT TTTAAACTTG AACTATTCCT TCCAGAAGAA 
TACCCAATGG CAGCACCTAA AGTACGTTTC ATGACCAAAA TTTATCATCC TAATGTAGAC 
AAGTTGGGAA GAATATGTTT AGATATTTTG AAAGATAAGT GGTCCCCAGC ACTGCAGATC 
CGCACAGTTC TGCTATCAAT CCAGGCTTTG TTAAGTGCTC CTAATCCAGA TGATCCATTA 
GCAAATGATG TAGCCGAGCA ATGGAAGACC AACGAAGCCC AAGCCATAGA AACAGCGAGA 
GCATGGACTA GGCTATATGC CATGAACAAT ATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ube2n ( XM_006514344.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006514407.1 Mus musculus ubiquitin-conjugating enzyme E2N (Ube2n), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu44970
Clone ID Related Accession (Same CDS sequence)	XM_006514344.4 , XM_006514344.3
Accession Version	XM_006514344.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	ubiquitin-conjugating enzyme E2 N isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006514344.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCGAC CCCGAGAGCC GGGCGGGGCC GCGGGCCGGG AGAGGCCGCT CCGGGAGGGC 
CACGGGGTTC TGCCGGCGAC AGCACAGGAA ACCCAGCGTT TGCTGGCAGA ACCAGTTCCT 
GGCATTAAAG CAGAACCAGA TGAGAGCAAC GCCCGTTATT TTCATGTGGT CATTGCTGGC 
CCCCAGGATT CCCCCTTTGA GGGAGGGACT TTTAAACTTG AACTATTCCT TCCAGAAGAA 
TACCCAATGG CAGCACCTAA AGTACGTTTC ATGACCAAAA TTTATCATCC TAATGTAGAC 
AAGTTGGGAA GAATATGTTT AGATATTTTG AAAGATAAGT GGTCCCCAGC ACTGCAGATC 
CGCACAGTTC TGCTATCAAT CCAGGCTTTG TTAAGTGCTC CTAATCCAGA TGATCCATTA 
GCAAATGATG TAGCCGAGCA ATGGAAGACC AACGAAGCCC AAGCCATAGA AACAGCGAGA 
GCATGGACTA GGCTATATGC CATGAACAAT ATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006514407.1
CDS	101..616
Translation	MDRPREPGGAAGRERPLREGHGVLPATAQETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI

Target ORF information:

RefSeq Version	XM_006514344.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ubiquitin-conjugating enzyme E2N (Ube2n), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006514344.3

ORF Insert Sequence:

ATGGACCGAC CCCGAGAGCC GGGCGGGGCC GCGGGCCGGG AGAGGCCGCT CCGGGAGGGC 
CACGGGGTTC TGCCGGCGAC AGCACAGGAA ACCCAGCGTT TGCTGGCAGA ACCAGTTCCT 
GGCATTAAAG CAGAACCAGA TGAGAGCAAC GCCCGTTATT TTCATGTGGT CATTGCTGGC 
CCCCAGGATT CCCCCTTTGA GGGAGGGACT TTTAAACTTG AACTATTCCT TCCAGAAGAA 
TACCCAATGG CAGCACCTAA AGTACGTTTC ATGACCAAAA TTTATCATCC TAATGTAGAC 
AAGTTGGGAA GAATATGTTT AGATATTTTG AAAGATAAGT GGTCCCCAGC ACTGCAGATC 
CGCACAGTTC TGCTATCAAT CCAGGCTTTG TTAAGTGCTC CTAATCCAGA TGATCCATTA 
GCAAATGATG TAGCCGAGCA ATGGAAGACC AACGAAGCCC AAGCCATAGA AACAGCGAGA 
GCATGGACTA GGCTATATGC CATGAACAAT ATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain.
Nature communications8(1)1271(2017 Nov)
Valnegri P,Huang J,Yamada T,Yang Y,Mejia LA,Cho HY,Oldenborg A,Bonni A

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Ube2n cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報