Arl4d cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Arl4d
Entrez Gene ID	80981
Full Name	ADP-ribosylation factor-like 4D
Synonyms	1110036H21Rik,ARL6,AW456149,Arf4l,Arfl4,Arl5
General protein information	Preferred Names ADP-ribosylation factor-like 4D Names ADP-ribosylation factor-like protein 4D ADP-ribosylation factor-like 5 ADP-ribosylation factor-like protein 4L ADP-ribosylation factor-like protein 5
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 D

mRNA and Protein(s)

mRNA	Protein	Name
NM_025404.3	NP_079680.1	ADP-ribosylation factor-like protein 4D

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Arl4d	NP_079680.1
Pan troglodytes (chimpanzee)	ARL4D	XP_003315468.1
Bos taurus (cattle)	ARL4D	NP_001069603.1
Homo sapiens (human)	ARL4D	NP_001652.2
Danio rerio (zebrafish)	arl4d	NP_955938.1
	ARL4D	XP_001097675.1
Canis lupus familiaris (dog)	ARL4D	XP_548073.2
Rattus norvegicus (Norway rat)	Arl4d	NP_001100522.1

Gene Ontology
Bibliography

Related articles in PubMed

Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.
Sandberg M, Flandin P, Silberberg S, Su-Feher L, Price JD, Hu JS, Kim C, Visel A, Nord AS, Rubenstein JLR
Neuron91(6)1260-1275(2016 Sep)

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J
Immunity43(4)690-702(2015 Oct)

Overexpression of the small GTPase Arl4D suppresses adipogenesis.
Yu J, Ka SO, Kwon KB, Lee SM, Park JW, Park BH
International journal of molecular medicine28(5)793-8(2011 Nov)

Epistasis contributes to the genetic buffering of plasma HDL cholesterol in mice.
Li RH, Churchill GA
Physiological genomics42A(4)228-34(2010 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results suggest that rapid reduction of Arl4D is required for adipogenesis to proceed.
Title: Overexpression of the small GTPase Arl4D suppresses adipogenesis.

analysis identified an epistatic interaction that plays a role in the buffering of HDL levels in C57BL/6J mice, and we have identified Arl4d as a candidate gene that mediates this effect.
Title: Epistasis contributes to the genetic buffering of plasma HDL cholesterol in mice.

Arl4D is a previously unknown regulator of neurite formation through cytohesin-2 and Arf6, providing another example that the functional interaction of two different small GTPases controls an important cellular function.
Title: Valproic acid-inducible Arl4D and cytohesin-2/ARNO, acting through the downstream Arf6, regulate neurite outgrowth in N1E-115 cells.

developmentally regulated ARL5, with its distinctive nuclear/nucleolar localization and interaction with HP1alpha, may play a role(s) in nuclear dynamics and/or signaling cascades during embryonic development
Title: A developmentally regulated ARF-like 5 protein (ARL5), localized to nuclei and nucleoli, interacts with heterochromatin protein 1.

The following Arl4d gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arl4d cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00412	NM_025404.3 Latest version!	Mus musculus ADP-ribosylation factor-like 4D (Arl4d), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Arl4d ( NM_025404.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079680.1 Mus musculus ADP-ribosylation factor-like 4D (Arl4d), mRNA.

Price & Availability↑

CloneID	OMu00412
Clone ID Related Accession (Same CDS sequence)	NM_025404.3
Accession Version	NM_025404.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-30
Organism	Mus musculus(house mouse)
Product	ADP-ribosylation factor-like protein 4D
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ830332.1 and BC016113.1. On or before Jun 4, 2008 this sequence version replaced NM_031160.1, XM_001471772.1, NM_025404.2. ##Evidence-Data-START## Transcript exon combination :: BC016113.1, AK004126.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGGGAACC ACTTGACTGA AATGGCCCCT ACAGCCTCGT CCTTTCTGCC GCACTTCCAG 
GCCCTGCATG TCGTCGTCAT TGGGTTGGAT TCCGCGGGGA AGACTTCCCT TCTTTACCGT 
CTCAAGTTCA AGGAGTTTGT CCAGAGCGTC CCCACCAAGG GCTTTAATAC TGAGAAGATC 
CGCGTGCCCC TGGGGGGTTC CCGTGGGATC ACTTTCCAAG TGTGGGATGT TGGGGGTCAG 
GAGAAGCTTC GGCCACTGTG GCGCTCCTAC ACCCGCCGGA CAGATGGACT GGTGTTTGTG 
GTGGACTCTG CAGAGACTGA GAGGTTAGAG GAAGCCAGAA TGGAGTTACA CCGGATCAGC 
AAGGCTTCCG ACAACCAGGG GGTGCCAGTG CTGGTGCTGG CCAACAAGCA GGACCAACCG 
GGGGCACTGA GTGCAGCCGA GGTGGAGAAG AGGCTGGCGG TCCGAGAGCT GGCAGCTGCC 
ACGCTCACCC ATGTGCAGGG CTGCAGTGCT GTGGACGGGC TGGGCCTGCA GCCAGGCCTG 
GAACATTTGT ATGAAATGAT CCTGAAGAGG AAGAAGGCAC CTCGGTCGAG CAAGAAGAGA 
CGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079680.1
CDS	200..805
Translation	MGNHLTEMAPTASSFLPHFQALHVVVIGLDSAGKTSLLYRLKFKEFVQSVPTKGFNTEKIRVPLGGSRGITFQVWDVGGQEKLRPLWRSYTRRTDGLVFVVDSAETERLEEARMELHRISKASDNQGVPVLVLANKQDQPGALSAAEVEKRLAVRELAAATLTHVQGCSAVDGLGLQPGLEHLYEMILKRKKAPRSSKKRR

Target ORF information:

RefSeq Version	NM_025404.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADP-ribosylation factor-like 4D (Arl4d), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025404.3

ORF Insert Sequence:

ATGGGGAACC ACTTGACTGA AATGGCCCCT ACAGCCTCGT CCTTTCTGCC GCACTTCCAG 
GCCCTGCATG TCGTCGTCAT TGGGTTGGAT TCCGCGGGGA AGACTTCCCT TCTTTACCGT 
CTCAAGTTCA AGGAGTTTGT CCAGAGCGTC CCCACCAAGG GCTTTAATAC TGAGAAGATC 
CGCGTGCCCC TGGGGGGTTC CCGTGGGATC ACTTTCCAAG TGTGGGATGT TGGGGGTCAG 
GAGAAGCTTC GGCCACTGTG GCGCTCCTAC ACCCGCCGGA CAGATGGACT GGTGTTTGTG 
GTGGACTCTG CAGAGACTGA GAGGTTAGAG GAAGCCAGAA TGGAGTTACA CCGGATCAGC 
AAGGCTTCCG ACAACCAGGG GGTGCCAGTG CTGGTGCTGG CCAACAAGCA GGACCAACCG 
GGGGCACTGA GTGCAGCCGA GGTGGAGAAG AGGCTGGCGG TCCGAGAGCT GGCAGCTGCC 
ACGCTCACCC ATGTGCAGGG CTGCAGTGCT GTGGACGGGC TGGGCCTGCA GCCAGGCCTG 
GAACATTTGT ATGAAATGAT CCTGAAGAGG AAGAAGGCAC CTCGGTCGAG CAAGAAGAGA 
CGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.
Neuron91(6)1260-1275(2016 Sep)
Sandberg M,Flandin P,Silberberg S,Su-Feher L,Price JD,Hu JS,Kim C,Visel A,Nord AS,Rubenstein JLR

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Immunity43(4)690-702(2015 Oct)
Ray JP,Staron MM,Shyer JA,Ho PC,Marshall HD,Gray SM,Laidlaw BJ,Araki K,Ahmed R,Kaech SM,Craft J

Overexpression of the small GTPase Arl4D suppresses adipogenesis.
International journal of molecular medicine28(5)793-8(2011 Nov)
Yu J,Ka SO,Kwon KB,Lee SM,Park JW,Park BH

Epistasis contributes to the genetic buffering of plasma HDL cholesterol in mice.
Physiological genomics42A(4)228-34(2010 Nov)
Li RH,Churchill GA