Gins3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gins3
Entrez Gene ID	78833
Full Name	GINS complex subunit 3 (Psf3 homolog)
Synonyms	2700085M18Rik,AI616142
General protein information	Preferred Names GINS complex subunit 3 (Psf3 homolog) Names DNA replication complex GINS protein PSF3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 C5-D1

mRNA and Protein(s)

mRNA	Protein	Name
NM_030198.3	NP_084474.1	DNA replication complex GINS protein PSF3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GINS3	XP_511004.1
Xenopus tropicalis (tropical clawed frog)	gins3	NP_001016123.1
Canis lupus familiaris (dog)	GINS3	XP_544380.2
Rattus norvegicus (Norway rat)	Gins3	NP_001100878.1
Homo sapiens (human)	GINS3	NP_073607.2
Bos taurus (cattle)	GINS3	NP_001069604.1
Mus musculus (house mouse)	Gins3	NP_084474.1
Danio rerio (zebrafish)	gins3	NP_001002874.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011132	XP_309515.4
Gallus gallus (chicken)	GINS3	XP_413991.2
Drosophila melanogaster (fruit fly)	Psf3	NP_572624.1
	GINS3	XP_001101868.1

Gene Ontology
Bibliography

Related articles in PubMed

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.
Zhou L, Dai H, Wu J, Zhou M, Yuan H, Du J, Yang L, Wu X, Xu H, Hua Y, Xu J, Zheng L, Shen B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(1)132-147(2017 01)

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ
PLoS genetics5(6)e1000511(2009 Jun)

A combined computational and experimental study on the structure-regulation relationships of putative mammalian DNA replication initiator GINS.
Hayashi R, Arauchi T, Tategu M, Goto Y, Yoshida K
Genomics, proteomics & bioinformatics4(3)156-64(2006 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

expression of mammalian GINS is regulated by 17beta-Estradiol-stimulated estrogen receptor alpha, and PSF3 acts as a gene responsive to transcription factor E2F1
Title: A combined computational and experimental study on the structure-regulation relationships of putative mammalian DNA replication initiator GINS.

The following Gins3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gins3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu08081	NM_030198.3 Latest version!	Mus musculus GINS complex subunit 3 (Psf3 homolog) (Gins3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gins3 ( NM_030198.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084474.1 Mus musculus GINS complex subunit 3 (Psf3 homolog) (Gins3), mRNA.

Price & Availability↑

CloneID	OMu08081
Clone ID Related Accession (Same CDS sequence)	NM_030198.3
Accession Version	NM_030198.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	DNA replication complex GINS protein PSF3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC113951.13. On May 1, 2007 this sequence version replaced NM_030198.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK019225.1, AK146574.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTCCGAGG CGTATTTCCC AGTGGAGTCG GGCGCTCTGG GGCCGGAGGA GAACTTCCTG 
TCTTTGGACG ACATCCTGAT GTCGCAGGAG AAGCTGCCGG TGCGGGTCGA GACGCCCATG 
CCGCGCCTGG GAGCCTTCTT CCTGGAGCGG GGCGCGGGCT CCGAGCCGGA CCATCCGCTC 
CCTCAGGGTA CAAAACTTGA ACTTCCCCTG TGGCTGGCTA AAGGACTCTT TGACCACAAG 
CGGCGCATCC TTTCTGTGGA ACTTCCCAAA ATGTACCAAG AGGGATGGAG GACTGTATTC 
AGTGCAGATG CTAATGTCGT GGACCTCCAC AAAATGGGGC CCCATTTCTA TGGGTTTGGC 
TCACAACTCC TGCATTTTGA CAGTCCGGAG AATGCAGATA TTTCCCAGTC TCTGCTGAAG 
ACTTTTATTG GACGGTTCCG CCGCATCATG GACTCCTCCC AGAATTCTTA CAATGAAGAC 
ACTTCAGCGC TGGTAGCCAG GTTAGATGAG ACAGAGAGGG GCTTATTTCA AATCGGGCAG 
AGAAGTCTAA ATGACTTTCA GAGTTGGGAA AAAGGACAAG CTTCTCAGAT TACAGCTTCC 
AGCCTCGTCC AGAATTATAA GAAAAGGAAA TTCACAAACA TGGAAGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084474.1
CDS	40..690
Translation	MSEAYFPVESGALGPEENFLSLDDILMSQEKLPVRVETPMPRLGAFFLERGAGSEPDHPLPQGTKLELPLWLAKGLFDHKRRILSVELPKMYQEGWRTVFSADANVVDLHKMGPHFYGFGSQLLHFDSPENADISQSLLKTFIGRFRRIMDSSQNSYNEDTSALVARLDETERGLFQIGQRSLNDFQSWEKGQASQITASSLVQNYKKRKFTNMED

Target ORF information:

RefSeq Version	NM_030198.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus GINS complex subunit 3 (Psf3 homolog) (Gins3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030198.3

ORF Insert Sequence:

ATGTCCGAGG CGTATTTCCC AGTGGAGTCG GGCGCTCTGG GGCCGGAGGA GAACTTCCTG 
TCTTTGGACG ACATCCTGAT GTCGCAGGAG AAGCTGCCGG TGCGGGTCGA GACGCCCATG 
CCGCGCCTGG GAGCCTTCTT CCTGGAGCGG GGCGCGGGCT CCGAGCCGGA CCATCCGCTC 
CCTCAGGGTA CAAAACTTGA ACTTCCCCTG TGGCTGGCTA AAGGACTCTT TGACCACAAG 
CGGCGCATCC TTTCTGTGGA ACTTCCCAAA ATGTACCAAG AGGGATGGAG GACTGTATTC 
AGTGCAGATG CTAATGTCGT GGACCTCCAC AAAATGGGGC CCCATTTCTA TGGGTTTGGC 
TCACAACTCC TGCATTTTGA CAGTCCGGAG AATGCAGATA TTTCCCAGTC TCTGCTGAAG 
ACTTTTATTG GACGGTTCCG CCGCATCATG GACTCCTCCC AGAATTCTTA CAATGAAGAC 
ACTTCAGCGC TGGTAGCCAG GTTAGATGAG ACAGAGAGGG GCTTATTTCA AATCGGGCAG 
AGAAGTCTAA ATGACTTTCA GAGTTGGGAA AAAGGACAAG CTTCTCAGAT TACAGCTTCC 
AGCCTCGTCC AGAATTATAA GAAAAGGAAA TTCACAAACA TGGAAGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology31(1)132-147(2017 01)
Zhou L,Dai H,Wu J,Zhou M,Yuan H,Du J,Yang L,Wu X,Xu H,Hua Y,Xu J,Zheng L,Shen B

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
PLoS genetics5(6)e1000511(2009 Jun)
Sansom SN,Griffiths DS,Faedo A,Kleinjan DJ,Ruan Y,Smith J,van Heyningen V,Rubenstein JL,Livesey FJ

A combined computational and experimental study on the structure-regulation relationships of putative mammalian DNA replication initiator GINS.
Genomics, proteomics & bioinformatics4(3)156-64(2006 Aug)
Hayashi R,Arauchi T,Tategu M,Goto Y,Yoshida K