Lce1a2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lce1a2
Entrez Gene ID	73722
Full Name	late cornified envelope 1A2
Synonyms	1110004E04Rik,Sprrl2
General protein information	Preferred Names late cornified envelope 1A2 Names late cornified envelope 1A2 small proline rich-like 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3\|3 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_028625.2	NP_082901.1	late cornified envelope 1A2

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Transcription Factor MafB Coordinates Epidermal Keratinocyte Differentiation.
Miyai M, Hamada M, Moriguchi T, Hiruma J, Kamitani-Kawamoto A, Watanabe H, Hara-Chikuma M, Takahashi K, Takahashi S, Kataoka K
The Journal of investigative dermatology136(9)1848-57(2016 Sep)

Fate and plasticity of the epidermis in response to congenital activation of BRAF.
Krishnaswami SR, Kumar S, Ordoukhanian P, Yu BD
The Journal of investigative dermatology135(2)481-9(2015 Feb)

Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators.
Nagarajan P, Chin SS, Wang D, Liu S, Sinha S, Garrett-Sinha LA
Journal of cell science123(Pt 20)3566-75(2010 Oct)

Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells.
Ezhkova E, Pasolli HA, Parker JS, Stokes N, Su IH, Hannon G, Tarakhovsky A, Fuchs E
Cell136(6)1122-35(2009 Mar)

Rodent Lce gene clusters; new nomenclature, gene organization, and divergence of human and rodent genes.
Brown SJ, Tilli CM, Jackson B, Avilion AA, MacLeod MC, Maltais LJ, Lovering RC, Byrne C
The Journal of investigative dermatology127(7)1782-6(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lce1a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lce1a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu05887	NM_028625.2 Latest version!	Mus musculus late cornified envelope 1A2 (Lce1a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lce1a2 ( NM_028625.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082901.1 Mus musculus late cornified envelope 1A2 (Lce1a2), mRNA.

Price & Availability↑

CloneID	OMu05887
Clone ID Related Accession (Same CDS sequence)	NM_028625.2
Accession Version	NM_028625.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Mus musculus(house mouse)
Product	late cornified envelope 1A2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK003412.1. On Sep 21, 2006 this sequence version replaced NM_028625.1. ##Evidence-Data-START## Transcript exon combination :: AK003412.1, BC100540.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END##

ATGTCCTGCC AGCAGAACCA GCAGCAGTGT CAGCCCCCTC CCAAGTGTCC TCCCAAGTGC 
CAGACCCCAA AATGCCCTCC AAAATGCCCC CCTAAGTGTC CTCCCAAGTG CCCCCCTGTG 
TCTTCCTGCT GTAGCCTGGG TTCTGGGGGT TGCTGTGGCT CCAGCTCTGG GGGCTGTTGC 
AGCTCTGGAG GCTGCTGCAG CTCTGGTGGC TGCTGCAGCT CTGGGGGTGG AGGCTGCTGC 
CTGAGCCACC ACAGACCTCG CAGATCCCTC CGTCGCCATC GCCATAGCTC TGGATGTTGT 
AGCAGTGGTG GCAGCAGTGG ATGCTGTGGC AGCAGTGGTG GCAGTGGTGG CTGCTGTGGA 
AGCAGTGGTG GCAGCAGTGG ATGCTGTGGC AGCAGTGGTG GCAGCAGTGG CTGCTGTGGC 
AGTAGCCAGC AGTCTGGGGG CTGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082901.1
CDS	75..524
Translation	MSCQQNQQQCQPPPKCPPKCQTPKCPPKCPPKCPPKCPPVSSCCSLGSGGCCGSSSGGCCSSGGCCSSGGCCSSGGGGCCLSHHRPRRSLRRHRHSSGCCSSGGSSGCCGSSGGSGGCCGSSGGSSGCCGSSGGSSGCCGSSQQSGGCC

Target ORF information:

RefSeq Version	NM_028625.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus late cornified envelope 1A2 (Lce1a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028625.2

ORF Insert Sequence:

ATGTCCTGCC AGCAGAACCA GCAGCAGTGT CAGCCCCCTC CCAAGTGTCC TCCCAAGTGC 
CAGACCCCAA AATGCCCTCC AAAATGCCCC CCTAAGTGTC CTCCCAAGTG CCCCCCTGTG 
TCTTCCTGCT GTAGCCTGGG TTCTGGGGGT TGCTGTGGCT CCAGCTCTGG GGGCTGTTGC 
AGCTCTGGAG GCTGCTGCAG CTCTGGTGGC TGCTGCAGCT CTGGGGGTGG AGGCTGCTGC 
CTGAGCCACC ACAGACCTCG CAGATCCCTC CGTCGCCATC GCCATAGCTC TGGATGTTGT 
AGCAGTGGTG GCAGCAGTGG ATGCTGTGGC AGCAGTGGTG GCAGTGGTGG CTGCTGTGGA 
AGCAGTGGTG GCAGCAGTGG ATGCTGTGGC AGCAGTGGTG GCAGCAGTGG CTGCTGTGGC 
AGTAGCCAGC AGTCTGGGGG CTGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transcription Factor MafB Coordinates Epidermal Keratinocyte Differentiation.
The Journal of investigative dermatology136(9)1848-57(2016 Sep)
Miyai M,Hamada M,Moriguchi T,Hiruma J,Kamitani-Kawamoto A,Watanabe H,Hara-Chikuma M,Takahashi K,Takahashi S,Kataoka K

Fate and plasticity of the epidermis in response to congenital activation of BRAF.
The Journal of investigative dermatology135(2)481-9(2015 Feb)
Krishnaswami SR,Kumar S,Ordoukhanian P,Yu BD

Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators.
Journal of cell science123(Pt 20)3566-75(2010 Oct)
Nagarajan P,Chin SS,Wang D,Liu S,Sinha S,Garrett-Sinha LA

Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells.
Cell136(6)1122-35(2009 Mar)
Ezhkova E,Pasolli HA,Parker JS,Stokes N,Su IH,Hannon G,Tarakhovsky A,Fuchs E

Rodent Lce gene clusters; new nomenclature, gene organization, and divergence of human and rodent genes.
The Journal of investigative dermatology127(7)1782-6(2007 Jul)
Brown SJ,Tilli CM,Jackson B,Avilion AA,MacLeod MC,Maltais LJ,Lovering RC,Byrne C