Clec2g cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Clec2g
Entrez Gene ID	70809
Full Name	C-type lectin domain family 2, member g
Synonyms	4632413B12Rik,Clr-c,Clr-d,Clrc,Clrd,Clrx,Ddv10,Ocilrp1
General protein information	Preferred Names C-type lectin domain family 2, member g Names C-type lectin domain family 2 member G C-type lectin-related protein C C-type lectin-related protein x variant 1 ocil-related protein 1 osteoclast inhibitory lectin related protein osteoclast inhibitory lectin-related protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 F3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001316752.1	NP_001303681.1	C-type lectin domain family 2 member G isoform 4
NM_001168224.1	NP_001161696.1	C-type lectin domain family 2 member G isoform 3
NM_027562.4	NP_081838.1	C-type lectin domain family 2 member G isoform 1
NM_001168223.1	NP_001161695.1	C-type lectin domain family 2 member G isoform 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Clec2i	NP_064653.1
Mus musculus (house mouse)	Clec2g	NP_001161695.1
Mus musculus (house mouse)	Clec2d	NP_444339.1

Gene Ontology
Bibliography

Related articles in PubMed

The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state.
Lowe KL, Navarro-N??ez L, B?n?zech C, Nayar S, Kingston BL, Nieswandt B, Barone F, Watson SP, Buckley CD, Desanti GE
European journal of immunology45(9)2484-93(2015 Sep)

Platelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling.
Navarro-N??ez L, Pollitt AY, Lowe K, Latif A, Nash GB, Watson SP
Thrombosis and haemostasis113(5)1109-20(2015 May)

Analysis of the mouse 129-strain Nkrp1-Clr gene cluster reveals conservation of genomic organization and functional receptor-ligand interactions despite significant allelic polymorphism.
Chen P, B?langer S, Aguilar OA, Zhang Q, St-Laurent A, Rahim MM, Makrigiannis AP, Carlyle JR
Immunogenetics63(10)627-40(2011 Oct)

Phylogenetic and functional conservation of the NKR-P1F and NKR-P1G receptors in rat and mouse.
Kveberg L, Dai KZ, Inngjerdingen M, Brooks CG, Fossum S, Vaage JT
Immunogenetics63(7)429-36(2011 Jul)

A novel mechanism of cytokine release in phagocytes induced by aggretin, a snake venom C-type lectin protein, through CLEC-2 ligation.
Chang CH, Chung CH, Hsu CC, Huang TY, Huang TF
Journal of thrombosis and haemostasis : JTH8(11)2563-70(2010 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Both circulating B lymphocytes and CD11b-high Gr-1-high myeloid cells lose CLEC-2 following entry into secondary lymphoid organs.
Title: The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state.

CLEC-2 is an adhesive receptor that supports platelet arrest to podoplanin under venous shear. Src/Syk-dependent signalling stabilises platelet adhesion to podoplanin.
Title: Platelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling.

aggretin may induce cytokine TNF-alpha/IL-6 release via interacting with CLEC-2 receptor and the subsequent MAPK and NF-kappaB activation in monocytes/macrophages
Title: A novel mechanism of cytokine release in phagocytes induced by aggretin, a snake venom C-type lectin protein, through CLEC-2 ligation.

Data suggest that DDV10 is the long form of Clec2 g (Clec2g-L), and DDV10/Clec2g-L may play a role in the stratification and/or cornification of epithelial cells during differentiation.
Title: Tissue-specific expression of Clec2g in mice.

The following Clec2g gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Clec2g cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu70574	NM_001316752.1 Latest version!	Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu04357	NM_027562.4 Latest version!	Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu58479	NM_001168223.1 Latest version!	Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu58492	NM_001168224.1 Latest version!	Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Clec2g ( NM_001316752.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001303681.1 Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu70574
Clone ID Related Accession (Same CDS sequence)	NM_001316752.1
Accession Version	NM_001316752.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	C-type lectin domain family 2 member G isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY137341.1, JF792239.1 and AC159305.3. On Oct 24, 2015 this sequence version replaced XM_011241465.1. Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (4) has a shorter and distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: JF792239.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCACTCT GTGCTTTCTG GTTTGTGTAT CACATGAATG CTCAGTGCCT AAAGAAGCCA 
GAAGAAGGCG AAAGCTCCCC CGGAACTGGA GGTGTACATT CTTATAAAAT TCTCCAAAGA 
AATAGTCTCA GAGCCATCTC CCCTGAGTCT TCTGCTAAGC TTTACTGCTG CTGTGGAGTG 
ATCATGGTCC TCACTGTAGC TGTAGTTGCT CTTTCTGTTG CTTTGCCAGC AACAAAGACA 
GAACAGATCC TAATCAACAA GACCTATGCT GCTTGCCCGA AAAACTGGAT TGGAGTTGGA 
AATAAATGTT TTTATTTTTC TGAATACACA AGTAACTGGA CATTCGCCCA GACCTTCTGC 
ATGGCACAAG AGGCCCAACT AGCTCGGTTT GACAACGAGA AGGAGCTGAA TTTCCTAATG 
AGATACAAGG CAAATTTTGA TTCCTGGATT GGACTGCACA GAGAGTCGTC AGAGCACCCT 
TGGAAGTGGA CAGACAACAC TGAGTATAAC AACATGATTC CCATCCAGGG AGTGGAAACA 
TGTGCCTACC TGAGCGGCAA TGGGATCAGC AGTTCCAGGC ACTATATACC TCGGATATGG 
ATCTGTAGCA AGCTTAACAA CTATAGCCTC CACTGCCCAA CTCCTGTTCC TGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001303681.1
CDS	179..835
Translation	MPLCAFWFVYHMNAQCLKKPEEGESSPGTGGVHSYKILQRNSLRAISPESSAKLYCCCGVIMVLTVAVVALSVALPATKTEQILINKTYAACPKNWIGVGNKCFYFSEYTSNWTFAQTFCMAQEAQLARFDNEKELNFLMRYKANFDSWIGLHRESSEHPWKWTDNTEYNNMIPIQGVETCAYLSGNGISSSRHYIPRIWICSKLNNYSLHCPTPVPV

Target ORF information:

RefSeq Version	NM_001316752.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001316752.1

ORF Insert Sequence:

ATGCCACTCT GTGCTTTCTG GTTTGTGTAT CACATGAATG CTCAGTGCCT AAAGAAGCCA 
GAAGAAGGCG AAAGCTCCCC CGGAACTGGA GGTGTACATT CTTATAAAAT TCTCCAAAGA 
AATAGTCTCA GAGCCATCTC CCCTGAGTCT TCTGCTAAGC TTTACTGCTG CTGTGGAGTG 
ATCATGGTCC TCACTGTAGC TGTAGTTGCT CTTTCTGTTG CTTTGCCAGC AACAAAGACA 
GAACAGATCC TAATCAACAA GACCTATGCT GCTTGCCCGA AAAACTGGAT TGGAGTTGGA 
AATAAATGTT TTTATTTTTC TGAATACACA AGTAACTGGA CATTCGCCCA GACCTTCTGC 
ATGGCACAAG AGGCCCAACT AGCTCGGTTT GACAACGAGA AGGAGCTGAA TTTCCTAATG 
AGATACAAGG CAAATTTTGA TTCCTGGATT GGACTGCACA GAGAGTCGTC AGAGCACCCT 
TGGAAGTGGA CAGACAACAC TGAGTATAAC AACATGATTC CCATCCAGGG AGTGGAAACA 
TGTGCCTACC TGAGCGGCAA TGGGATCAGC AGTTCCAGGC ACTATATACC TCGGATATGG 
ATCTGTAGCA AGCTTAACAA CTATAGCCTC CACTGCCCAA CTCCTGTTCC TGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clec2g ( NM_027562.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081838.1 Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu04357
Clone ID Related Accession (Same CDS sequence)	NM_027562.4
Accession Version	NM_027562.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 810bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	C-type lectin domain family 2 member G isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK014570.1 and AK137753.1. On Dec 4, 2009 this sequence version replaced NM_027562.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK014570.1, BC117543.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849376, SAMN00849387 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACATTA CAAGGGCTTC CCTACCTATG CTCAACACCA CTTGCAGCTG CAGGAGGGAG 
AAGTGGAATT TCCTAGGGAG ATACGAGGGG ACTTTTGACT ACTGGATCGG CCTGCACAGA 
GCGTCGTCTA AGCACCCTTG GATGTGGACA GACAACACTG AGTATAACAA CATGTTTGTG 
TATCACATGA ATGCTCAGTG CCTAAAGAAG CCAGAAGAAG GCGAAAGCTC CCCCGGAACT 
GGAGGTGTAC ATTCTTATAA AATTCTCCAA AGAAATAGTC TCAGAGCCAT CTCCCCTGAG 
TCTTCTGCTA AGCTTTACTG CTGCTGTGGA GTGATCATGG TCCTCACTGT AGCTGTAGTT 
GCTCTTTCTG TTGCTTTGCC AGCAACAAAG ACAGAACAGA TCCTAATCAA CAAGACCTAT 
GCTGCTTGCC CGAAAAACTG GATTGGAGTT GGAAATAAAT GTTTTTATTT TTCTGAATAC 
ACAAGTAACT GGACATTCGC CCAGACCTTC TGCATGGCAC AAGAGGCCCA ACTAGCTCGG 
TTTGACAACG AGAAGGAGCT GAATTTCCTA ATGAGATACA AGGCAAATTT TGATTCCTGG 
ATTGGACTGC ACAGAGAGTC GTCAGAGCAC CCTTGGAAGT GGACAGACAA CACTGAGTAT 
AACAACATGA TTCCCATCCA GGGAGTGGAA ACATGTGCCT ACCTGAGCGG CAATGGGATC 
AGCAGTTCCA GGCACTATAT ACCTCGGATA TGGATCTGTA GCAAGCTTAA CAACTATAGC 
CTCCACTGCC CAACTCCTGT TCCTGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081838.1
CDS	37..846
Translation	MNITRASLPMLNTTCSCRREKWNFLGRYEGTFDYWIGLHRASSKHPWMWTDNTEYNNMFVYHMNAQCLKKPEEGESSPGTGGVHSYKILQRNSLRAISPESSAKLYCCCGVIMVLTVAVVALSVALPATKTEQILINKTYAACPKNWIGVGNKCFYFSEYTSNWTFAQTFCMAQEAQLARFDNEKELNFLMRYKANFDSWIGLHRESSEHPWKWTDNTEYNNMIPIQGVETCAYLSGNGISSSRHYIPRIWICSKLNNYSLHCPTPVPV

Target ORF information:

RefSeq Version	NM_027562.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027562.4

ORF Insert Sequence:

ATGAACATTA CAAGGGCTTC CCTACCTATG CTCAACACCA CTTGCAGCTG CAGGAGGGAG 
AAGTGGAATT TCCTAGGGAG ATACGAGGGG ACTTTTGACT ACTGGATCGG CCTGCACAGA 
GCGTCGTCTA AGCACCCTTG GATGTGGACA GACAACACTG AGTATAACAA CATGTTTGTG 
TATCACATGA ATGCTCAGTG CCTAAAGAAG CCAGAAGAAG GCGAAAGCTC CCCCGGAACT 
GGAGGTGTAC ATTCTTATAA AATTCTCCAA AGAAATAGTC TCAGAGCCAT CTCCCCTGAG 
TCTTCTGCTA AGCTTTACTG CTGCTGTGGA GTGATCATGG TCCTCACTGT AGCTGTAGTT 
GCTCTTTCTG TTGCTTTGCC AGCAACAAAG ACAGAACAGA TCCTAATCAA CAAGACCTAT 
GCTGCTTGCC CGAAAAACTG GATTGGAGTT GGAAATAAAT GTTTTTATTT TTCTGAATAC 
ACAAGTAACT GGACATTCGC CCAGACCTTC TGCATGGCAC AAGAGGCCCA ACTAGCTCGG 
TTTGACAACG AGAAGGAGCT GAATTTCCTA ATGAGATACA AGGCAAATTT TGATTCCTGG 
ATTGGACTGC ACAGAGAGTC GTCAGAGCAC CCTTGGAAGT GGACAGACAA CACTGAGTAT 
AACAACATGA TTCCCATCCA GGGAGTGGAA ACATGTGCCT ACCTGAGCGG CAATGGGATC 
AGCAGTTCCA GGCACTATAT ACCTCGGATA TGGATCTGTA GCAAGCTTAA CAACTATAGC 
CTCCACTGCC CAACTCCTGT TCCTGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clec2g ( NM_001168223.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001161695.1 Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu58479
Clone ID Related Accession (Same CDS sequence)	NM_001168223.1
Accession Version	NM_001168223.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 639bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	C-type lectin domain family 2 member G isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY137342.1, AK137753.1 and AK014570.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY137342.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTTGTGT ATCACATGAA TGCTCAGTGC CTAAAGAAGC CAGAAGAAGG CGAAAGCTCC 
CCCGGAACTG GAGGTGTACA TTCTTATAAA ATTCTCCAAA GAAATAGTCT CAGAGCCATC 
TCCCCTGAGT CTTCTGCTAA GCTTTACTGC TGCTGTGGAG TGATCATGGT CCTCACTGTA 
GCTGTAGTTG CTCTTTCTGT TGCTTTGCCA GCAACAAAGA CAGAACAGAT CCTAATCAAC 
AAGACCTATG CTGCTTGCCC GAAAAACTGG ATTGGAGTTG GAAATAAATG TTTTTATTTT 
TCTGAATACA CAAGTAACTG GACATTCGCC CAGACCTTCT GCATGGCACA AGAGGCCCAA 
CTAGCTCGGT TTGACAACGA GAAGGAGCTG AATTTCCTAA TGAGATACAA GGCAAATTTT 
GATTCCTGGA TTGGACTGCA CAGAGAGTCG TCAGAGCACC CTTGGAAGTG GACAGACAAC 
ACTGAGTATA ACAACATGAT TCCCATCCAG GGAGTGGAAA CATGTGCCTA CCTGAGCGGC 
AATGGGATCA GCAGTTCCAG GCACTATATA CCTCGGATAT GGATCTGTAG CAAGCTTAAC 
AACTATAGCC TCCACTGCCC AACTCCTGTT CCTGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001161695.1
CDS	34..672
Translation	MFVYHMNAQCLKKPEEGESSPGTGGVHSYKILQRNSLRAISPESSAKLYCCCGVIMVLTVAVVALSVALPATKTEQILINKTYAACPKNWIGVGNKCFYFSEYTSNWTFAQTFCMAQEAQLARFDNEKELNFLMRYKANFDSWIGLHRESSEHPWKWTDNTEYNNMIPIQGVETCAYLSGNGISSSRHYIPRIWICSKLNNYSLHCPTPVPV

Target ORF information:

RefSeq Version	NM_001168223.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001168223.1

ORF Insert Sequence:

ATGTTTGTGT ATCACATGAA TGCTCAGTGC CTAAAGAAGC CAGAAGAAGG CGAAAGCTCC 
CCCGGAACTG GAGGTGTACA TTCTTATAAA ATTCTCCAAA GAAATAGTCT CAGAGCCATC 
TCCCCTGAGT CTTCTGCTAA GCTTTACTGC TGCTGTGGAG TGATCATGGT CCTCACTGTA 
GCTGTAGTTG CTCTTTCTGT TGCTTTGCCA GCAACAAAGA CAGAACAGAT CCTAATCAAC 
AAGACCTATG CTGCTTGCCC GAAAAACTGG ATTGGAGTTG GAAATAAATG TTTTTATTTT 
TCTGAATACA CAAGTAACTG GACATTCGCC CAGACCTTCT GCATGGCACA AGAGGCCCAA 
CTAGCTCGGT TTGACAACGA GAAGGAGCTG AATTTCCTAA TGAGATACAA GGCAAATTTT 
GATTCCTGGA TTGGACTGCA CAGAGAGTCG TCAGAGCACC CTTGGAAGTG GACAGACAAC 
ACTGAGTATA ACAACATGAT TCCCATCCAG GGAGTGGAAA CATGTGCCTA CCTGAGCGGC 
AATGGGATCA GCAGTTCCAG GCACTATATA CCTCGGATAT GGATCTGTAG CAAGCTTAAC 
AACTATAGCC TCCACTGCCC AACTCCTGTT CCTGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clec2g ( NM_001168224.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001161696.1 Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu58492
Clone ID Related Accession (Same CDS sequence)	NM_001168224.1
Accession Version	NM_001168224.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	C-type lectin domain family 2 member G isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY137341.1, AK137753.1 and AK014570.1. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK137753.1, JF792238.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAATGCTC AGTGCCTAAA GAAGCCAGAA GAAGGCGAAA GCTCCCCCGG AACTGGAGGT 
GTACATTCTT ATAAAATTCT CCAAAGAAAT AGTCTCAGAG CCATCTCCCC TGAGTCTTCT 
GCTAAGCTTT ACTGCTGCTG TGGAGTGATC ATGGTCCTCA CTGTAGCTGT AGTTGCTCTT 
TCTGTTGCTT TGCCAGCAAC AAAGACAGAA CAGATCCTAA TCAACAAGAC CTATGCTGCT 
TGCCCGAAAA ACTGGATTGG AGTTGGAAAT AAATGTTTTT ATTTTTCTGA ATACACAAGT 
AACTGGACAT TCGCCCAGAC CTTCTGCATG GCACAAGAGG CCCAACTAGC TCGGTTTGAC 
AACGAGAAGG AGCTGAATTT CCTAATGAGA TACAAGGCAA ATTTTGATTC CTGGATTGGA 
CTGCACAGAG AGTCGTCAGA GCACCCTTGG AAGTGGACAG ACAACACTGA GTATAACAAC 
ATGATTCCCA TCCAGGGAGT GGAAACATGT GCCTACCTGA GCGGCAATGG GATCAGCAGT 
TCCAGGCACT ATATACCTCG GATATGGATC TGTAGCAAGC TTAACAACTA TAGCCTCCAC 
TGCCCAACTC CTGTTCCTGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001161696.1
CDS	161..784
Translation	MNAQCLKKPEEGESSPGTGGVHSYKILQRNSLRAISPESSAKLYCCCGVIMVLTVAVVALSVALPATKTEQILINKTYAACPKNWIGVGNKCFYFSEYTSNWTFAQTFCMAQEAQLARFDNEKELNFLMRYKANFDSWIGLHRESSEHPWKWTDNTEYNNMIPIQGVETCAYLSGNGISSSRHYIPRIWICSKLNNYSLHCPTPVPV

Target ORF information:

RefSeq Version	NM_001168224.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus C-type lectin domain family 2, member g (Clec2g), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001168224.1

ORF Insert Sequence:

ATGAATGCTC AGTGCCTAAA GAAGCCAGAA GAAGGCGAAA GCTCCCCCGG AACTGGAGGT 
GTACATTCTT ATAAAATTCT CCAAAGAAAT AGTCTCAGAG CCATCTCCCC TGAGTCTTCT 
GCTAAGCTTT ACTGCTGCTG TGGAGTGATC ATGGTCCTCA CTGTAGCTGT AGTTGCTCTT 
TCTGTTGCTT TGCCAGCAAC AAAGACAGAA CAGATCCTAA TCAACAAGAC CTATGCTGCT 
TGCCCGAAAA ACTGGATTGG AGTTGGAAAT AAATGTTTTT ATTTTTCTGA ATACACAAGT 
AACTGGACAT TCGCCCAGAC CTTCTGCATG GCACAAGAGG CCCAACTAGC TCGGTTTGAC 
AACGAGAAGG AGCTGAATTT CCTAATGAGA TACAAGGCAA ATTTTGATTC CTGGATTGGA 
CTGCACAGAG AGTCGTCAGA GCACCCTTGG AAGTGGACAG ACAACACTGA GTATAACAAC 
ATGATTCCCA TCCAGGGAGT GGAAACATGT GCCTACCTGA GCGGCAATGG GATCAGCAGT 
TCCAGGCACT ATATACCTCG GATATGGATC TGTAGCAAGC TTAACAACTA TAGCCTCCAC 
TGCCCAACTC CTGTTCCTGT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state.
European journal of immunology45(9)2484-93(2015 Sep)
Lowe KL,Navarro-N??ez L,B?n?zech C,Nayar S,Kingston BL,Nieswandt B,Barone F,Watson SP,Buckley CD,Desanti GE

Platelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling.
Thrombosis and haemostasis113(5)1109-20(2015 May)
Navarro-N??ez L,Pollitt AY,Lowe K,Latif A,Nash GB,Watson SP

Analysis of the mouse 129-strain Nkrp1-Clr gene cluster reveals conservation of genomic organization and functional receptor-ligand interactions despite significant allelic polymorphism.
Immunogenetics63(10)627-40(2011 Oct)
Chen P,B?langer S,Aguilar OA,Zhang Q,St-Laurent A,Rahim MM,Makrigiannis AP,Carlyle JR

Phylogenetic and functional conservation of the NKR-P1F and NKR-P1G receptors in rat and mouse.
Immunogenetics63(7)429-36(2011 Jul)
Kveberg L,Dai KZ,Inngjerdingen M,Brooks CG,Fossum S,Vaage JT

A novel mechanism of cytokine release in phagocytes induced by aggretin, a snake venom C-type lectin protein, through CLEC-2 ligation.
Journal of thrombosis and haemostasis : JTH8(11)2563-70(2010 Nov)
Chang CH,Chung CH,Hsu CC,Huang TY,Huang TF