Ifi35 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ifi35
Entrez Gene ID	70110
Full Name	interferon-induced protein 35
Synonyms	2010008K16Rik,AW986054,IFP35,ifi-35
General protein information	Preferred Names interferon-induced protein 35 Names interferon-induced 35 kDa protein homolog IFP 35
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 D

mRNA and Protein(s)

mRNA	Protein	Name
NM_027320.4	NP_081596.1	interferon-induced 35 kDa protein homolog

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	IFI35	XP_001158983.1
Rattus norvegicus (Norway rat)	Ifi35	NP_001009625.1
Xenopus tropicalis (tropical clawed frog)	ifi35	XP_002932558.2
Homo sapiens (human)	IFI35	NP_005524.2
	IFI35	XP_001112861.1
Mus musculus (house mouse)	Ifi35	NP_081596.1
Danio rerio (zebrafish)	ifi35	XP_688060.4
Bos taurus (cattle)	IFI35	NP_001068930.1
Gallus gallus (chicken)	IFI35	XP_418132.1
Canis lupus familiaris (dog)	IFI35	XP_548077.2

Gene Ontology
Bibliography

Related articles in PubMed

NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury.
Xiahou Z, Wang X, Shen J, Zhu X, Xu F, Hu R, Guo D, Li H, Tian Y, Liu Y, Liang H
Nature communications8(1)950(2017 10)

USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.
Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P
Nature immunology18(1)54-63(2017 Jan)

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ifi35 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ifi35 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu04043	NM_027320.4 Latest version!	Mus musculus interferon-induced protein 35 (Ifi35), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ifi35 ( NM_027320.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081596.1 Mus musculus interferon-induced protein 35 (Ifi35), mRNA.

Price & Availability↑

CloneID	OMu04043
Clone ID Related Accession (Same CDS sequence)	NM_027320.4
Accession Version	NM_027320.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 861bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	interferon-induced 35 kDa protein homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL590996.12. On Apr 30, 2007 this sequence version replaced NM_027320.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK131884.1, AK008161.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTCTGTGA CCCTGCAAAC TGTCCTCTAC AGTCTTCAGG AGGAGCAAGC CAGGCTCAAG 
ATGAGGCTGC AGGAGCTGCA GCAGCTCAAA AGGGAGCGCA CAGGCTCTCC CGGAGCCAAG 
ATCCCATTCT CAGTACCTGA AGTTCCTCTG GTATTCCAAG GCCAAACTAA GCAGGGCAGG 
CAAGTGCCCA AGTTTGTAGT TTCTAACTTG AAGGTCTGCT GCCCTCTGCC TGAAGGTTCT 
GCTCTGGTCA CCTTTGAGGA CCCCAAAGTG GTTGATCGGT TGCTACAACA AAAGGAACAC 
AGAGTTAACT TAGAGGACTG CCGGCTGCGG GTGCAGGTCC AGCCCTTGGA GCTGCCTGTG 
GTGACCAACA TTCAGGTGTC CAGCCAGCCA GATAACCACA GGGTGCTCGT TAGTGGTTTT 
CCTGCTGGAC TTAGGCTGAG TGAAGAGGAA CTGTTGGACA AGCTGGAGAT CTTCTTTGGC 
AAGGCCAAGA ATGGAGGTGG GGATGTAGAG ACCCGGGAGA TGCTGCAAGG GACCGTCATG 
CTAGGGTTTG CTGATGAAGA AGTGGCCCAG CACTTATGCC AGATTGGCCA GTTCAGAGTC 
CCACTGGACC GGCAGCAGGT CCTCCTGAGG GTCTCTCCCT ATGTGAGTGG TGAGATCCAG 
AAAGCCGAGA TCAAATTCCA GCAAGCCCCT CATTCAGTGC TGGTGACAAA TATTCCTGAT 
GTCATGGATG CCCAGGAACT GCATGACATC CTTGAGATCC ACTTCCAGAA GCCCACTCGT 
GGGGGCGGGG AGGTGGAGGC CCTGACAGTT GTGCCTTCAG GGCAGCAGGG CCTGGCTATC 
TTCACTTCCG AGTCAAGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081596.1
CDS	191..1051
Translation	MSVTLQTVLYSLQEEQARLKMRLQELQQLKRERTGSPGAKIPFSVPEVPLVFQGQTKQGRQVPKFVVSNLKVCCPLPEGSALVTFEDPKVVDRLLQQKEHRVNLEDCRLRVQVQPLELPVVTNIQVSSQPDNHRVLVSGFPAGLRLSEEELLDKLEIFFGKAKNGGGDVETREMLQGTVMLGFADEEVAQHLCQIGQFRVPLDRQQVLLRVSPYVSGEIQKAEIKFQQAPHSVLVTNIPDVMDAQELHDILEIHFQKPTRGGGEVEALTVVPSGQQGLAIFTSESS

Target ORF information:

RefSeq Version	NM_027320.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus interferon-induced protein 35 (Ifi35), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027320.4

ORF Insert Sequence:

ATGTCTGTGA CCCTGCAAAC TGTCCTCTAC AGTCTTCAGG AGGAGCAAGC CAGGCTCAAG 
ATGAGGCTGC AGGAGCTGCA GCAGCTCAAA AGGGAGCGCA CAGGCTCTCC CGGAGCCAAG 
ATCCCATTCT CAGTACCTGA AGTTCCTCTG GTATTCCAAG GCCAAACTAA GCAGGGCAGG 
CAAGTGCCCA AGTTTGTAGT TTCTAACTTG AAGGTCTGCT GCCCTCTGCC TGAAGGTTCT 
GCTCTGGTCA CCTTTGAGGA CCCCAAAGTG GTTGATCGGT TGCTACAACA AAAGGAACAC 
AGAGTTAACT TAGAGGACTG CCGGCTGCGG GTGCAGGTCC AGCCCTTGGA GCTGCCTGTG 
GTGACCAACA TTCAGGTGTC CAGCCAGCCA GATAACCACA GGGTGCTCGT TAGTGGTTTT 
CCTGCTGGAC TTAGGCTGAG TGAAGAGGAA CTGTTGGACA AGCTGGAGAT CTTCTTTGGC 
AAGGCCAAGA ATGGAGGTGG GGATGTAGAG ACCCGGGAGA TGCTGCAAGG GACCGTCATG 
CTAGGGTTTG CTGATGAAGA AGTGGCCCAG CACTTATGCC AGATTGGCCA GTTCAGAGTC 
CCACTGGACC GGCAGCAGGT CCTCCTGAGG GTCTCTCCCT ATGTGAGTGG TGAGATCCAG 
AAAGCCGAGA TCAAATTCCA GCAAGCCCCT CATTCAGTGC TGGTGACAAA TATTCCTGAT 
GTCATGGATG CCCAGGAACT GCATGACATC CTTGAGATCC ACTTCCAGAA GCCCACTCGT 
GGGGGCGGGG AGGTGGAGGC CCTGACAGTT GTGCCTTCAG GGCAGCAGGG CCTGGCTATC 
TTCACTTCCG AGTCAAGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury.
Nature communications8(1)950(2017 10)
Xiahou Z,Wang X,Shen J,Zhu X,Xu F,Hu R,Guo D,Li H,Tian Y,Liu Y,Liang H

USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation.
Nature immunology18(1)54-63(2017 Jan)
Torre S,Polyak MJ,Langlais D,Fodil N,Kennedy JM,Radovanovic I,Berghout J,Leiva-Torres GA,Krawczyk CM,Ilangumaran S,Mossman K,Liang C,Knobeloch KP,Healy LM,Antel J,Arbour N,Prat A,Majewski J,Lathrop M,Vidal SM,Gros P

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W