C8g cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	C8g
Entrez Gene ID	69379
Full Name	complement component 8, gamma polypeptide
General protein information	Preferred Names complement component 8, gamma polypeptide Names complement component C8 gamma chain complement component 8, gamma subunit novel lipocalin protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 A3\|2 17.31 cM
Summary	This gene encodes a secreted protein that is a core component of the complement 8 (C8) complex. C8 is part of the membrane attack complex which participates in the innate immune response against bacterial pathogens. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012].

mRNA and Protein(s)

mRNA	Protein	Name
XM_011239171.2	XP_011237473.1	complement component C8 gamma chain isoform X1
XM_011239171.3	XP_011237473.1	complement component C8 gamma chain isoform X1
NM_001271777.1	NP_001258706.1	complement component C8 gamma chain isoform 2
NM_027062.2	NP_081338.1	complement component C8 gamma chain isoform 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	C8G	XP_003312464.1
Canis lupus familiaris (dog)	C8G	XP_537791.1
Mus musculus (house mouse)	C8g	NP_081338.1
Xenopus tropicalis (tropical clawed frog)	c8g	XP_002942766.2
Homo sapiens (human)	C8G	NP_000597.2
Danio rerio (zebrafish)	c8g	NP_957157.1
	LOC721647	XP_001117839.1
Rattus norvegicus (Norway rat)	C8g	NP_001100025.1
Gallus gallus (chicken)	C8G	XP_001234027.2

Gene Ontology
Bibliography

Related articles in PubMed

Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit.
Slade DJ, Lovelace LL, Chruszcz M, Minor W, Lebioda L, Sodetz JM
Journal of molecular biology379(2)331-42(2008 May)

Role of the human C8 subunits in complement-mediated bacterial killing: evidence that C8 gamma is not essential.
Parker CL, Sodetz JM
Molecular immunology39(7-8)453-8(2002 Nov)

Interaction between the C8 alpha-gamma and C8 beta subunits of human complement C8: role of the C8 beta N-terminal thrombospondin type 1 module and membrane attack complex/perforin domain.
Musingarimi P, Plumb ME, Sodetz JM
Biochemistry41(37)11255-60(2002 Sep)

Human complement protein C8 gamma.
Schreck SF, Parker C, Plumb ME, Sodetz JM
Biochimica et biophysica acta1482(1-2)199-208(2000 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results describe the crystal structure of the human ortholog C8 alpha MACPF domain disulfide-linked to C8 gamma (alphaMACPF-gamma) at 2.15 A resolution.
Title: Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit.

This is a study of the human orthologs of C8 alpha, beta, and gamma. C8 gamma is not required for complement-mediated killing of Gram-negative bacteria.
Title: Role of the human C8 subunits in complement-mediated bacterial killing: evidence that C8 gamma is not essential.

This is a study of the human C8 orthologs. Binding of C8 gamma subunit to C8 beta is dependent on the thrombospondin type 1 module, low-density lipoprotein receptor class A module, and membrane attack complex/perforin domain of C8 beta.
Title: Interaction between the C8 alpha-gamma and C8 beta subunits of human complement C8: role of the C8 beta N-terminal thrombospondin type 1 module and membrane attack complex/perforin domain.

A review of the human C8 gamma ortholog.
Title: Human complement protein C8 gamma.

The following C8g gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C8g cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu03530	NM_027062.2 Latest version!	Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu17073	NM_001271777.1 Latest version!	Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu70422	XM_011239171.3 Latest version!	Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu70422	XM_011239171.2	Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

C8g ( NM_027062.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081338.1 Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu03530
Clone ID Related Accession (Same CDS sequence)	NM_027062.2
Accession Version	NM_027062.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 609bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Mus musculus(house mouse)
Product	complement component C8 gamma chain isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL732557.4, BY090016.1 and AK005962.1. On Nov 20, 2012 this sequence version replaced NM_027062.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC019967.1, BI331536.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGTCTC CAGGGGCTGT GTTGTTCTTC ACCCTGCTCT TGACAGCCAG TTCGCTGGGC 
CAAAGGACTC GAAAGCCTAT TGGGTCTACC TCCCCCATCA GCACTATCCA GGCCCAGGTC 
AATTTCAGTG CTCAGAAGTT TGCAGGGACA TGGCTCCTGG TGGCTGTGGG CTCTTCGTGC 
CGCTTTCTTC AGGAGCAGGG ACACCGAGCT GAGGCCACCA CATTGCACGC AGCTCCCCAG 
GGTGCAGCTA TGGCTGTCAG CACCTTCCGA AAGCTAGATG GGATATGTTG GCAGGTACGC 
CAACTCTTTG AGAACACAGG GGTCCCTGGC CGCTTCTTGT TCCAAGTCTC ACGGGCCCGT 
GGACCAGTGC ATATGGTGGT TGCTGAGACT GACTATCAGA GCTTTGCCAT CCTGTACCTG 
GAACAGGGAA GGAAGCTGTC TGTGAAACTA TACGTCCGCT CACTGCCAGT GAATGACTCT 
GTCCTGGATG TGTTTGAGCG GCGAGTCAGG GAAGCCAACC TGACAGAAGA TCAGATTCTT 
TTCTTTCCCA AGTATGGTTT CTGCGAGACT GCGGACCAAT TACACATCCT GAACGAGGTG 
CCGCGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081338.1
CDS	276..884
Translation	MLSPGAVLFFTLLLTASSLGQRTRKPIGSTSPISTIQAQVNFSAQKFAGTWLLVAVGSSCRFLQEQGHRAEATTLHAAPQGAAMAVSTFRKLDGICWQVRQLFENTGVPGRFLFQVSRARGPVHMVVAETDYQSFAILYLEQGRKLSVKLYVRSLPVNDSVLDVFERRVREANLTEDQILFFPKYGFCETADQLHILNEVPR

Target ORF information:

RefSeq Version	NM_027062.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027062.2

ORF Insert Sequence:

ATGCTGTCTC CAGGGGCTGT GTTGTTCTTC ACCCTGCTCT TGACAGCCAG TTCGCTGGGC 
CAAAGGACTC GAAAGCCTAT TGGGTCTACC TCCCCCATCA GCACTATCCA GGCCCAGGTC 
AATTTCAGTG CTCAGAAGTT TGCAGGGACA TGGCTCCTGG TGGCTGTGGG CTCTTCGTGC 
CGCTTTCTTC AGGAGCAGGG ACACCGAGCT GAGGCCACCA CATTGCACGC AGCTCCCCAG 
GGTGCAGCTA TGGCTGTCAG CACCTTCCGA AAGCTAGATG GGATATGTTG GCAGGTACGC 
CAACTCTTTG AGAACACAGG GGTCCCTGGC CGCTTCTTGT TCCAAGTCTC ACGGGCCCGT 
GGACCAGTGC ATATGGTGGT TGCTGAGACT GACTATCAGA GCTTTGCCAT CCTGTACCTG 
GAACAGGGAA GGAAGCTGTC TGTGAAACTA TACGTCCGCT CACTGCCAGT GAATGACTCT 
GTCCTGGATG TGTTTGAGCG GCGAGTCAGG GAAGCCAACC TGACAGAAGA TCAGATTCTT 
TTCTTTCCCA AGTATGGTTT CTGCGAGACT GCGGACCAAT TACACATCCT GAACGAGGTG 
CCGCGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C8g ( NM_001271777.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001258706.1 Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu17073
Clone ID Related Accession (Same CDS sequence)	NM_001271777.1
Accession Version	NM_001271777.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 507bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Mus musculus(house mouse)
Product	complement component C8 gamma chain isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK005962.1 and AL732557.4. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK005962.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTTCCC CAATGCTACA GGGCACAGGG AGGCAGTTTG CAGGGACATG GCTCCTGGTG 
GCTGTGGGCT CTTCGTGCCG CTTTCTTCAG GAGCAGGGAC ACCGAGCTGA GGCCACCACA 
TTGCACGCAG CTCCCCAGGG TGCAGCTATG GCTGTCAGCA CCTTCCGAAA GCTAGATGGG 
ATATGTTGGC AGGTACGCCA ACTCTTTGAG AACACAGGGG TCCCTGGCCG CTTCTTGTTC 
CAAGTCTCAC GGGCCCGTGG ACCAGTGCAT ATGGTGGTTG CTGAGACTGA CTATCAGAGC 
TTTGCCATCC TGTACCTGGA ACAGGGAAGG AAGCTGTCTG TGAAACTATA CGTCCGCTCA 
CTGCCAGTGA ATGACTCTGT CCTGGATGTG TTTGAGCGGC GAGTCAGGGA AGCCAACCTG 
ACAGAAGATC AGATTCTTTT CTTTCCCAAG TATGGTTTCT GCGAGACTGC GGACCAATTA 
CACATCCTGA ACGAGGTGCC GCGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258706.1
CDS	157..663
Translation	MPSPMLQGTGRQFAGTWLLVAVGSSCRFLQEQGHRAEATTLHAAPQGAAMAVSTFRKLDGICWQVRQLFENTGVPGRFLFQVSRARGPVHMVVAETDYQSFAILYLEQGRKLSVKLYVRSLPVNDSVLDVFERRVREANLTEDQILFFPKYGFCETADQLHILNEVPR

Target ORF information:

RefSeq Version	NM_001271777.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271777.1

ORF Insert Sequence:

ATGCCTTCCC CAATGCTACA GGGCACAGGG AGGCAGTTTG CAGGGACATG GCTCCTGGTG 
GCTGTGGGCT CTTCGTGCCG CTTTCTTCAG GAGCAGGGAC ACCGAGCTGA GGCCACCACA 
TTGCACGCAG CTCCCCAGGG TGCAGCTATG GCTGTCAGCA CCTTCCGAAA GCTAGATGGG 
ATATGTTGGC AGGTACGCCA ACTCTTTGAG AACACAGGGG TCCCTGGCCG CTTCTTGTTC 
CAAGTCTCAC GGGCCCGTGG ACCAGTGCAT ATGGTGGTTG CTGAGACTGA CTATCAGAGC 
TTTGCCATCC TGTACCTGGA ACAGGGAAGG AAGCTGTCTG TGAAACTATA CGTCCGCTCA 
CTGCCAGTGA ATGACTCTGT CCTGGATGTG TTTGAGCGGC GAGTCAGGGA AGCCAACCTG 
ACAGAAGATC AGATTCTTTT CTTTCCCAAG TATGGTTTCT GCGAGACTGC GGACCAATTA 
CACATCCTGA ACGAGGTGCC GCGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C8g ( XM_011239171.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011237473.1 Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu70422
Clone ID Related Accession (Same CDS sequence)	XM_011239171.2 , XM_011239171.3
Accession Version	XM_011239171.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	complement component C8 gamma chain isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011239171.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGTCA GCACCTTCCG AAAGCTAGAT GGGATATGTT GGCAGGTACG CCAACTCTTT 
GAGAACACAG GGGTCCCTGG CCGCTTCTTG TTCCAAGTCT CACGGGCCCG TGGACCAGTG 
CATATGGTGG TTGCTGAGAC TGACTATCAG AGCTTTGCCA TCCTGTACCT GGAACAGGGA 
AGGAAGCTGT CTGTGAAACT ATACGTCCGC TCACTGCCAG TGAATGACTC TGTCCTGGAT 
GTGTTTGAGC GGCGAGTCAG GGAAGCCAAC CTGACAGAAG ATCAGATTCT TTTCTTTCCC 
AAGTATGGTT TCTGCGAGAC TGCGGACCAA TTACACATCC TGAACGAGGT GCCGCGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011237473.1
CDS	199..558
Translation	MAVSTFRKLDGICWQVRQLFENTGVPGRFLFQVSRARGPVHMVVAETDYQSFAILYLEQGRKLSVKLYVRSLPVNDSVLDVFERRVREANLTEDQILFFPKYGFCETADQLHILNEVPR

Target ORF information:

RefSeq Version	XM_011239171.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011239171.2

ORF Insert Sequence:

ATGGCTGTCA GCACCTTCCG AAAGCTAGAT GGGATATGTT GGCAGGTACG CCAACTCTTT 
GAGAACACAG GGGTCCCTGG CCGCTTCTTG TTCCAAGTCT CACGGGCCCG TGGACCAGTG 
CATATGGTGG TTGCTGAGAC TGACTATCAG AGCTTTGCCA TCCTGTACCT GGAACAGGGA 
AGGAAGCTGT CTGTGAAACT ATACGTCCGC TCACTGCCAG TGAATGACTC TGTCCTGGAT 
GTGTTTGAGC GGCGAGTCAG GGAAGCCAAC CTGACAGAAG ATCAGATTCT TTTCTTTCCC 
AAGTATGGTT TCTGCGAGAC TGCGGACCAA TTACACATCC TGAACGAGGT GCCGCGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C8g ( XM_011239171.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011237473.1 Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu70422
Clone ID Related Accession (Same CDS sequence)	XM_011239171.2 , XM_011239171.3
Accession Version	XM_011239171.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	complement component C8 gamma chain isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011239171.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGTCA GCACCTTCCG AAAGCTAGAT GGGATATGTT GGCAGGTACG CCAACTCTTT 
GAGAACACAG GGGTCCCTGG CCGCTTCTTG TTCCAAGTCT CACGGGCCCG TGGACCAGTG 
CATATGGTGG TTGCTGAGAC TGACTATCAG AGCTTTGCCA TCCTGTACCT GGAACAGGGA 
AGGAAGCTGT CTGTGAAACT ATACGTCCGC TCACTGCCAG TGAATGACTC TGTCCTGGAT 
GTGTTTGAGC GGCGAGTCAG GGAAGCCAAC CTGACAGAAG ATCAGATTCT TTTCTTTCCC 
AAGTATGGTT TCTGCGAGAC TGCGGACCAA TTACACATCC TGAACGAGGT GCCGCGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011237473.1
CDS	275..634
Translation	MAVSTFRKLDGICWQVRQLFENTGVPGRFLFQVSRARGPVHMVVAETDYQSFAILYLEQGRKLSVKLYVRSLPVNDSVLDVFERRVREANLTEDQILFFPKYGFCETADQLHILNEVPR

Target ORF information:

RefSeq Version	XM_011239171.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus complement component 8, gamma polypeptide (C8g), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011239171.3

ORF Insert Sequence:

ATGGCTGTCA GCACCTTCCG AAAGCTAGAT GGGATATGTT GGCAGGTACG CCAACTCTTT 
GAGAACACAG GGGTCCCTGG CCGCTTCTTG TTCCAAGTCT CACGGGCCCG TGGACCAGTG 
CATATGGTGG TTGCTGAGAC TGACTATCAG AGCTTTGCCA TCCTGTACCT GGAACAGGGA 
AGGAAGCTGT CTGTGAAACT ATACGTCCGC TCACTGCCAG TGAATGACTC TGTCCTGGAT 
GTGTTTGAGC GGCGAGTCAG GGAAGCCAAC CTGACAGAAG ATCAGATTCT TTTCTTTCCC 
AAGTATGGTT TCTGCGAGAC TGCGGACCAA TTACACATCC TGAACGAGGT GCCGCGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit.
Journal of molecular biology379(2)331-42(2008 May)
Slade DJ,Lovelace LL,Chruszcz M,Minor W,Lebioda L,Sodetz JM

Role of the human C8 subunits in complement-mediated bacterial killing: evidence that C8 gamma is not essential.
Molecular immunology39(7-8)453-8(2002 Nov)
Parker CL,Sodetz JM

Interaction between the C8 alpha-gamma and C8 beta subunits of human complement C8: role of the C8 beta N-terminal thrombospondin type 1 module and membrane attack complex/perforin domain.
Biochemistry41(37)11255-60(2002 Sep)
Musingarimi P,Plumb ME,Sodetz JM

Human complement protein C8 gamma.
Biochimica et biophysica acta1482(1-2)199-208(2000 Oct)
Schreck SF,Parker C,Plumb ME,Sodetz JM