Cd209b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cd209b
Entrez Gene ID	69165
Full Name	CD209b antigen
Synonyms	1810030I22Rik,DC-SIGNR1,OtB7,SIGNR1,mSIGNR1
General protein information	Preferred Names CD209b antigen Names CD209 antigen-like protein B DC-SIGN-related protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 A1.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006508870.3	XP_006508933.1	CD209 antigen-like protein B isoform X1
NM_026972.5	NP_081248.4	CD209 antigen-like protein B isoform a
NM_001037800.3	NP_001032889.3	CD209 antigen-like protein B isoform b
NM_001287211.1	NP_001274140.1	CD209 antigen-like protein B isoform c

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cd209b	NP_001163868.1
	CD209L2	NP_001028123.1
Mus musculus (house mouse)	Cd209b	NP_081248.4
Pan troglodytes (chimpanzee)	CD209L2	NP_001123945.1

Gene Ontology
Bibliography

Related articles in PubMed

Engineered Sialylation of Pathogenic Antibodies In?Vivo Attenuates Autoimmune Disease.
Pagan JD, Kitaoka M, Anthony RM
Cell(2017 Dec)

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

Lewis Lung Cancer Cells Promote SIGNR1(CD209b)-Mediated Macrophages Polarization Induced by IL-4 to Facilitate Immune Evasion.
Yan X, Li W, Pan L, Fu E, Xie Y, Chen M, Mu D
Journal of cellular biochemistry117(5)1158-66(2016 May)

SIGN-R1 and complement factors are involved in the systemic clearance of radiation-induced apoptotic cells in whole-body irradiated mice.
Park JY, Loh S, Cho EH, Choi HJ, Na TY, Nemeno JG, Lee JI, Yoon TJ, Choi IS, Lee M, Lee JS, Kang YS
Biochemical and biophysical research communications463(4)1064-70(2015 Aug)

DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice.
Cox N, Pilling D, Gomer RH
Proceedings of the National Academy of Sciences of the United States of America112(27)8385-90(2015 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that SIGNR1(CD209b) expressed in Lewis lung cancer cell-educated macrophages appears to mediate IL-4-induced RAW264.7 macrophage polarization and thus facilitate lung cancer evasion.
Title: Lewis Lung Cancer Cells Promote SIGNR1(CD209b)-Mediated Macrophages Polarization Induced by IL-4 to Facilitate Immune Evasion.

SIGNR1-mediated phagocytosis but not SIGNR1-mediated endocytosis and cell adhesion, suppresses the TLR4-mediated production of specific proinflammatory cytokines via PI3 kinase signaling.
Title: SIGNR1-mediated phagocytosis, but not SIGNR1-mediated endocytosis or cell adhesion, suppresses LPS-induced secretion of IL-6 from murine macrophages.

The subtle carbohydrate preference of SIGNR1 as a phagocytic receptor or as an adhesion molecule is altered depending on the function.
Title: Comparison of the carbohydrate preference of SIGNR1 as a phagocytic receptor with the preference as an adhesion molecule.

mediates uptake of mannose-decorated particles leading to cell maturation of peritoneal DC-like cells
Title: C-type lectin receptor SIGNR1 expressed on peritoneal phagocytic cells with an immature dendritic cell-like phenotype is involved in uptake of oligomannose-coated liposomes and subsequent cell maturation.

SIGNR1 is involved in the inhibition of DC maturation
Title: Secretory IgA induces tolerogenic dendritic cells through SIGNR1 dampening autoimmunity in mice.

The following Cd209b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd209b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu16894	NM_001287211.1 Latest version!	Mus musculus CD209b antigen (Cd209b), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu40456	XM_006508870.3 Latest version!	Mus musculus CD209b antigen (Cd209b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu16742	NM_026972.5 Latest version!	Mus musculus CD209b antigen (Cd209b), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OMu16752	NM_001037800.3 Latest version!	Mus musculus CD209b antigen (Cd209b), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cd209b ( NM_001287211.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001274140.1 Mus musculus CD209b antigen (Cd209b), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu16894
Clone ID Related Accession (Same CDS sequence)	NM_001287211.1
Accession Version	NM_001287211.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	CD209 antigen-like protein B isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF424803.1, AF374471.1, AC121948.2 and AK138999.1. Transcript Variant: This variant (5) lacks an alternate in-frame exon in the 5' coding region, and includes an additional in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF424799.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGTGACT CCACAGAAGC CAAGATGCAG CCTCTTAGCT CCATGGACGA TGATGAGTTG 
ATGGTCAGCG GCAGCAGGTA TTCTATTAAA AGCTCCAGAC TACGACCAAA TTCTGGAATC 
AAGTGTTTGG CAGTCTCCAA AACCCCAAAT ACCGAGAGGC AGAAGGAACA AGAGAAGATC 
CTCCAGGAAC TGACCCAGCT GACAGATGAG CTTACGTCCA GGATCCCCAT CTCCCAAGGG 
AAGAATGAGT CCATGCAGGC GAAGATCACT GAGCAACTGA TGCAGCTGAA AACTGAACTC 
TTGTCCAGGA TTCCCATCTT CCAGGGGCAG AATGAGTCCA TACAAGAGAA GATCTCTGAG 
CAACTGATGC AGCTGAAGGC TGAACTTCTT TCCAAGATCT CCAGCTTCCC GGTAAAGGAT 
GATTCTAAGC AGGAGAAGAT CTACCAACAG CTGGTACAGA TGAAGACTGA ACTCTTCCGC 
CTGTGTCGAC TCTGCCCCTG GGACTGGACA TTCCTCCTAG GAAATTGTTA CTTCTTCTCC 
AAGTCCCAGC GGAACTGGAA TGACGCCGTC ACAGCTTGCA AAGAAGTGAA GGCTCAACTA 
GTCATCATCA ATAGTGATGA AGAGCAGACC TTCCTGCAGC AGACTTCTAA GGCTAAAGGA 
CCAACCTGGA TGGGCCTGTC AGACCTGAAG AAGGAGGCCA CGTGGCTCTG GGTAGATGGT 
TCTACTCTGT CATCCAGCAG ACCCAGGCAT GCCCCCATCT CCAGAGGAAG GCCCATCTAC 
AATATGCATT CTGGAAGGAG ATTCCAGAAA TATTGGAATA GAGGGGAGCC TAACAACATC 
GGTGAGGAAG ACTGTGTCGA ATTTGCTGGG GATGGCTGGA ATGACTCTAA ATGTGAACTC 
AAAAAGTTCT GGATCTGCAA GAAGTCTGCA ACCCCATGCA CTGAAGGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001274140.1
CDS	50..1000
Translation	MSDSTEAKMQPLSSMDDDELMVSGSRYSIKSSRLRPNSGIKCLAVSKTPNTERQKEQEKILQELTQLTDELTSRIPISQGKNESMQAKITEQLMQLKTELLSRIPIFQGQNESIQEKISEQLMQLKAELLSKISSFPVKDDSKQEKIYQQLVQMKTELFRLCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSSRPRHAPISRGRPIYNMHSGRRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCTEG

Target ORF information:

RefSeq Version	NM_001287211.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD209b antigen (Cd209b), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001287211.1

ORF Insert Sequence:

ATGAGTGACT CCACAGAAGC CAAGATGCAG CCTCTTAGCT CCATGGACGA TGATGAGTTG 
ATGGTCAGCG GCAGCAGGTA TTCTATTAAA AGCTCCAGAC TACGACCAAA TTCTGGAATC 
AAGTGTTTGG CAGTCTCCAA AACCCCAAAT ACCGAGAGGC AGAAGGAACA AGAGAAGATC 
CTCCAGGAAC TGACCCAGCT GACAGATGAG CTTACGTCCA GGATCCCCAT CTCCCAAGGG 
AAGAATGAGT CCATGCAGGC GAAGATCACT GAGCAACTGA TGCAGCTGAA AACTGAACTC 
TTGTCCAGGA TTCCCATCTT CCAGGGGCAG AATGAGTCCA TACAAGAGAA GATCTCTGAG 
CAACTGATGC AGCTGAAGGC TGAACTTCTT TCCAAGATCT CCAGCTTCCC GGTAAAGGAT 
GATTCTAAGC AGGAGAAGAT CTACCAACAG CTGGTACAGA TGAAGACTGA ACTCTTCCGC 
CTGTGTCGAC TCTGCCCCTG GGACTGGACA TTCCTCCTAG GAAATTGTTA CTTCTTCTCC 
AAGTCCCAGC GGAACTGGAA TGACGCCGTC ACAGCTTGCA AAGAAGTGAA GGCTCAACTA 
GTCATCATCA ATAGTGATGA AGAGCAGACC TTCCTGCAGC AGACTTCTAA GGCTAAAGGA 
CCAACCTGGA TGGGCCTGTC AGACCTGAAG AAGGAGGCCA CGTGGCTCTG GGTAGATGGT 
TCTACTCTGT CATCCAGCAG ACCCAGGCAT GCCCCCATCT CCAGAGGAAG GCCCATCTAC 
AATATGCATT CTGGAAGGAG ATTCCAGAAA TATTGGAATA GAGGGGAGCC TAACAACATC 
GGTGAGGAAG ACTGTGTCGA ATTTGCTGGG GATGGCTGGA ATGACTCTAA ATGTGAACTC 
AAAAAGTTCT GGATCTGCAA GAAGTCTGCA ACCCCATGCA CTGAAGGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd209b ( XM_006508870.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006508933.1 Mus musculus CD209b antigen (Cd209b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu40456
Clone ID Related Accession (Same CDS sequence)	XM_006508870.3
Accession Version	XM_006508870.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	CD209 antigen-like protein B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006508870.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACCAGG GGACAGCGGC AACCATGAGT GACTCCACAG AAGCCAAGAT GCAGCCTCTT 
AGCTCCATGG ACGATGATGA GTTGATGGTC AGCGGCAGCA GGTATTCTAT TAAAAGCTCC 
AGACTACGAC CAAATTCTGG AATCAAGTGT TTGGCAGGAT GCTCGGGACA CAGCCAAGTC 
CCCTTGGTCC TGCAGCTGCT CTCCTTCCTG TTCTTGGCTG GGCTCCTGCT GATCATTCTT 
TTCCAAGTCT CCAAAACCCC AAATACCGAG AGGCAGAAGG AACAAGAGAA GATCCTCCAG 
GAACTGACCC AGCTGACAGA TGAGCTTACG TCCAGGATCC CCATCTCCCA AGGGAAGAAT 
GAGTCCATGC AGGCGAAGAT CACTGAGCAA CTGATGCAGC TGAAAACTGA ACTCTTGTCC 
AGGATTCCCA TCTTCCAGGG GCAGAATGAG TCCATACAAG AGAAGATCTC TGAGCAACTG 
ATGCAGCTGA AGGCTGAACT TCTTTCCAAG ATCTCCAGCT TCCCGGTAAA GGATGATTCT 
AAGCAGGAGA AGATCTACCA ACAGCTGGTA CAGATGAAGA CTGAACTCTT CCGCCTGTGT 
CGACTCTGCC CCTGGGACTG GACATTCCTC CTAGGAAATT GTTACTTCTT CTCCAAGTCC 
CAGCGGAACT GGAATGACGC CGTCACAGCT TGCAAAGAAG TGAAGGCTCA ACTAGTCATC 
ATCAATAGTG ATGAAGAGCA GACCTTCCTG CAGCAGACTT CTAAGGCTAA AGGACCAACC 
TGGATGGGCC TGTCAGACCT GAAGAAGGAG GCCACGTGGC TCTGGGTAGA TGGTTCTACT 
CTGTCATCCA GCCAGCAGAC CCAGGCATGC CCCCATCTCC AGAGGAAGGC CCATCTACAA 
TATGCATTCT GGAAGGAGAT TCCAGAAATA TTGGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006508933.1
CDS	23..961
Translation	MHQGTAATMSDSTEAKMQPLSSMDDDELMVSGSRYSIKSSRLRPNSGIKCLAGCSGHSQVPLVLQLLSFLFLAGLLLIILFQVSKTPNTERQKEQEKILQELTQLTDELTSRIPISQGKNESMQAKITEQLMQLKTELLSRIPIFQGQNESIQEKISEQLMQLKAELLSKISSFPVKDDSKQEKIYQQLVQMKTELFRLCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSSQQTQACPHLQRKAHLQYAFWKEIPEILE

Target ORF information:

RefSeq Version	XM_006508870.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD209b antigen (Cd209b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006508870.3

ORF Insert Sequence:

ATGCACCAGG GGACAGCGGC AACCATGAGT GACTCCACAG AAGCCAAGAT GCAGCCTCTT 
AGCTCCATGG ACGATGATGA GTTGATGGTC AGCGGCAGCA GGTATTCTAT TAAAAGCTCC 
AGACTACGAC CAAATTCTGG AATCAAGTGT TTGGCAGGAT GCTCGGGACA CAGCCAAGTC 
CCCTTGGTCC TGCAGCTGCT CTCCTTCCTG TTCTTGGCTG GGCTCCTGCT GATCATTCTT 
TTCCAAGTCT CCAAAACCCC AAATACCGAG AGGCAGAAGG AACAAGAGAA GATCCTCCAG 
GAACTGACCC AGCTGACAGA TGAGCTTACG TCCAGGATCC CCATCTCCCA AGGGAAGAAT 
GAGTCCATGC AGGCGAAGAT CACTGAGCAA CTGATGCAGC TGAAAACTGA ACTCTTGTCC 
AGGATTCCCA TCTTCCAGGG GCAGAATGAG TCCATACAAG AGAAGATCTC TGAGCAACTG 
ATGCAGCTGA AGGCTGAACT TCTTTCCAAG ATCTCCAGCT TCCCGGTAAA GGATGATTCT 
AAGCAGGAGA AGATCTACCA ACAGCTGGTA CAGATGAAGA CTGAACTCTT CCGCCTGTGT 
CGACTCTGCC CCTGGGACTG GACATTCCTC CTAGGAAATT GTTACTTCTT CTCCAAGTCC 
CAGCGGAACT GGAATGACGC CGTCACAGCT TGCAAAGAAG TGAAGGCTCA ACTAGTCATC 
ATCAATAGTG ATGAAGAGCA GACCTTCCTG CAGCAGACTT CTAAGGCTAA AGGACCAACC 
TGGATGGGCC TGTCAGACCT GAAGAAGGAG GCCACGTGGC TCTGGGTAGA TGGTTCTACT 
CTGTCATCCA GCCAGCAGAC CCAGGCATGC CCCCATCTCC AGAGGAAGGC CCATCTACAA 
TATGCATTCT GGAAGGAGAT TCCAGAAATA TTGGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd209b ( NM_026972.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081248.4 Mus musculus CD209b antigen (Cd209b), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu16742
Clone ID Related Accession (Same CDS sequence)	NM_026972.5
Accession Version	NM_026972.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	CD209 antigen-like protein B isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF424803.1, AF373409.1 and AK138999.1. On Dec 7, 2013 this sequence version replaced NM_026972.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK138999.1, AF373409.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGTGACT CCACAGAAGC CAAGATGCAG CCTCTTAGCT CCATGGACGA TGATGAGTTG 
ATGGTCAGCG GCAGCAGGTA TTCTATTAAA AGCTCCAGAC TACGACCAAA TTCTGGAATC 
AAGTGTTTGG CAGGATGCTC GGGACACAGC CAAGTCCCCT TGGTCCTGCA GCTGCTCTCC 
TTCCTGTTCT TGGCTGGGCT CCTGCTGATC ATTCTTTTCC AAGTCTCCAA AACCCCAAAT 
ACCGAGAGGC AGAAGGAACA AGAGAAGATC CTCCAGGAAC TGACCCAGCT GACAGATGAG 
CTTACGTCCA GGATCCCCAT CTCCCAAGGG AAGAATGAGT CCATGCAGGC GAAGATCACT 
GAGCAACTGA TGCAGCTGAA AACTGAACTC TTGTCCAGGA TTCCCATCTT CCAGGGGCAG 
AATGAGTCCA TACAAGAGAA GATCTCTGAG CAACTGATGC AGCTGAAGGC TGAACTTCTT 
TCCAAGATCT CCAGCTTCCC GGTAAAGGAT GATTCTAAGC AGGAGAAGAT CTACCAACAG 
CTGGTACAGA TGAAGACTGA ACTCTTCCGC CTGTGTCGAC TCTGCCCCTG GGACTGGACA 
TTCCTCCTAG GAAATTGTTA CTTCTTCTCC AAGTCCCAGC GGAACTGGAA TGACGCCGTC 
ACAGCTTGCA AAGAAGTGAA GGCTCAACTA GTCATCATCA ATAGTGATGA AGAGCAGACC 
TTCCTGCAGC AGACTTCTAA GGCTAAAGGA CCAACCTGGA TGGGCCTGTC AGACCTGAAG 
AAGGAGGCCA CGTGGCTCTG GGTAGATGGT TCTACTCTGT CATCCAGATT CCAGAAATAT 
TGGAATAGAG GGGAGCCTAA CAACATCGGT GAGGAAGACT GTGTCGAATT TGCTGGGGAT 
GGCTGGAATG ACTCTAAATG TGAACTCAAA AAGTTCTGGA TCTGCAAGAA GTCTGCAACC 
CCATGCACTG AAGGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081248.4
CDS	50..1027
Translation	MSDSTEAKMQPLSSMDDDELMVSGSRYSIKSSRLRPNSGIKCLAGCSGHSQVPLVLQLLSFLFLAGLLLIILFQVSKTPNTERQKEQEKILQELTQLTDELTSRIPISQGKNESMQAKITEQLMQLKTELLSRIPIFQGQNESIQEKISEQLMQLKAELLSKISSFPVKDDSKQEKIYQQLVQMKTELFRLCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCTEG

Target ORF information:

RefSeq Version	NM_026972.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD209b antigen (Cd209b), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026972.5

ORF Insert Sequence:

ATGAGTGACT CCACAGAAGC CAAGATGCAG CCTCTTAGCT CCATGGACGA TGATGAGTTG 
ATGGTCAGCG GCAGCAGGTA TTCTATTAAA AGCTCCAGAC TACGACCAAA TTCTGGAATC 
AAGTGTTTGG CAGGATGCTC GGGACACAGC CAAGTCCCCT TGGTCCTGCA GCTGCTCTCC 
TTCCTGTTCT TGGCTGGGCT CCTGCTGATC ATTCTTTTCC AAGTCTCCAA AACCCCAAAT 
ACCGAGAGGC AGAAGGAACA AGAGAAGATC CTCCAGGAAC TGACCCAGCT GACAGATGAG 
CTTACGTCCA GGATCCCCAT CTCCCAAGGG AAGAATGAGT CCATGCAGGC GAAGATCACT 
GAGCAACTGA TGCAGCTGAA AACTGAACTC TTGTCCAGGA TTCCCATCTT CCAGGGGCAG 
AATGAGTCCA TACAAGAGAA GATCTCTGAG CAACTGATGC AGCTGAAGGC TGAACTTCTT 
TCCAAGATCT CCAGCTTCCC GGTAAAGGAT GATTCTAAGC AGGAGAAGAT CTACCAACAG 
CTGGTACAGA TGAAGACTGA ACTCTTCCGC CTGTGTCGAC TCTGCCCCTG GGACTGGACA 
TTCCTCCTAG GAAATTGTTA CTTCTTCTCC AAGTCCCAGC GGAACTGGAA TGACGCCGTC 
ACAGCTTGCA AAGAAGTGAA GGCTCAACTA GTCATCATCA ATAGTGATGA AGAGCAGACC 
TTCCTGCAGC AGACTTCTAA GGCTAAAGGA CCAACCTGGA TGGGCCTGTC AGACCTGAAG 
AAGGAGGCCA CGTGGCTCTG GGTAGATGGT TCTACTCTGT CATCCAGATT CCAGAAATAT 
TGGAATAGAG GGGAGCCTAA CAACATCGGT GAGGAAGACT GTGTCGAATT TGCTGGGGAT 
GGCTGGAATG ACTCTAAATG TGAACTCAAA AAGTTCTGGA TCTGCAAGAA GTCTGCAACC 
CCATGCACTG AAGGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cd209b ( NM_001037800.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001032889.3 Mus musculus CD209b antigen (Cd209b), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu16752
Clone ID Related Accession (Same CDS sequence)	NM_001037800.3
Accession Version	NM_001037800.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	CD209 antigen-like protein B isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF424803.1, AF374471.1 and AK138999.1. On Dec 7, 2013 this sequence version replaced NM_001037800.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF374471.1, AF424798.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGTGACT CCACAGAAGC CAAGATGCAG CCTCTTAGCT CCATGGACGA TGATGAGTTG 
ATGGTCAGCG GCAGCAGGTA TTCTATTAAA AGCTCCAGAC TACGACCAAA TTCTGGAATC 
AAGTGTTTGG CAGTCTCCAA AACCCCAAAT ACCGAGAGGC AGAAGGAACA AGAGAAGATC 
CTCCAGGAAC TGACCCAGCT GACAGATGAG CTTACGTCCA GGATCCCCAT CTCCCAAGGG 
AAGAATGAGT CCATGCAGGC GAAGATCACT GAGCAACTGA TGCAGCTGAA AACTGAACTC 
TTGTCCAGGA TTCCCATCTT CCAGGGGCAG AATGAGTCCA TACAAGAGAA GATCTCTGAG 
CAACTGATGC AGCTGAAGGC TGAACTTCTT TCCAAGATCT CCAGCTTCCC GGTAAAGGAT 
GATTCTAAGC AGGAGAAGAT CTACCAACAG CTGGTACAGA TGAAGACTGA ACTCTTCCGC 
CTGTGTCGAC TCTGCCCCTG GGACTGGACA TTCCTCCTAG GAAATTGTTA CTTCTTCTCC 
AAGTCCCAGC GGAACTGGAA TGACGCCGTC ACAGCTTGCA AAGAAGTGAA GGCTCAACTA 
GTCATCATCA ATAGTGATGA AGAGCAGACC TTCCTGCAGC AGACTTCTAA GGCTAAAGGA 
CCAACCTGGA TGGGCCTGTC AGACCTGAAG AAGGAGGCCA CGTGGCTCTG GGTAGATGGT 
TCTACTCTGT CATCCAGATT CCAGAAATAT TGGAATAGAG GGGAGCCTAA CAACATCGGT 
GAGGAAGACT GTGTCGAATT TGCTGGGGAT GGCTGGAATG ACTCTAAATG TGAACTCAAA 
AAGTTCTGGA TCTGCAAGAA GTCTGCAACC CCATGCACTG AAGGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032889.3
CDS	50..937
Translation	MSDSTEAKMQPLSSMDDDELMVSGSRYSIKSSRLRPNSGIKCLAVSKTPNTERQKEQEKILQELTQLTDELTSRIPISQGKNESMQAKITEQLMQLKTELLSRIPIFQGQNESIQEKISEQLMQLKAELLSKISSFPVKDDSKQEKIYQQLVQMKTELFRLCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCTEG

Target ORF information:

RefSeq Version	NM_001037800.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus CD209b antigen (Cd209b), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037800.3

ORF Insert Sequence:

ATGAGTGACT CCACAGAAGC CAAGATGCAG CCTCTTAGCT CCATGGACGA TGATGAGTTG 
ATGGTCAGCG GCAGCAGGTA TTCTATTAAA AGCTCCAGAC TACGACCAAA TTCTGGAATC 
AAGTGTTTGG CAGTCTCCAA AACCCCAAAT ACCGAGAGGC AGAAGGAACA AGAGAAGATC 
CTCCAGGAAC TGACCCAGCT GACAGATGAG CTTACGTCCA GGATCCCCAT CTCCCAAGGG 
AAGAATGAGT CCATGCAGGC GAAGATCACT GAGCAACTGA TGCAGCTGAA AACTGAACTC 
TTGTCCAGGA TTCCCATCTT CCAGGGGCAG AATGAGTCCA TACAAGAGAA GATCTCTGAG 
CAACTGATGC AGCTGAAGGC TGAACTTCTT TCCAAGATCT CCAGCTTCCC GGTAAAGGAT 
GATTCTAAGC AGGAGAAGAT CTACCAACAG CTGGTACAGA TGAAGACTGA ACTCTTCCGC 
CTGTGTCGAC TCTGCCCCTG GGACTGGACA TTCCTCCTAG GAAATTGTTA CTTCTTCTCC 
AAGTCCCAGC GGAACTGGAA TGACGCCGTC ACAGCTTGCA AAGAAGTGAA GGCTCAACTA 
GTCATCATCA ATAGTGATGA AGAGCAGACC TTCCTGCAGC AGACTTCTAA GGCTAAAGGA 
CCAACCTGGA TGGGCCTGTC AGACCTGAAG AAGGAGGCCA CGTGGCTCTG GGTAGATGGT 
TCTACTCTGT CATCCAGATT CCAGAAATAT TGGAATAGAG GGGAGCCTAA CAACATCGGT 
GAGGAAGACT GTGTCGAATT TGCTGGGGAT GGCTGGAATG ACTCTAAATG TGAACTCAAA 
AAGTTCTGGA TCTGCAAGAA GTCTGCAACC CCATGCACTG AAGGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Engineered Sialylation of Pathogenic Antibodies In?Vivo Attenuates Autoimmune Disease.
Cell(2017 Dec)
Pagan JD,Kitaoka M,Anthony RM

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

Lewis Lung Cancer Cells Promote SIGNR1(CD209b)-Mediated Macrophages Polarization Induced by IL-4 to Facilitate Immune Evasion.
Journal of cellular biochemistry117(5)1158-66(2016 May)
Yan X,Li W,Pan L,Fu E,Xie Y,Chen M,Mu D

SIGN-R1 and complement factors are involved in the systemic clearance of radiation-induced apoptotic cells in whole-body irradiated mice.
Biochemical and biophysical research communications463(4)1064-70(2015 Aug)
Park JY,Loh S,Cho EH,Choi HJ,Na TY,Nemeno JG,Lee JI,Yoon TJ,Choi IS,Lee M,Lee JS,Kang YS

DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice.
Proceedings of the National Academy of Sciences of the United States of America112(27)8385-90(2015 Jul)
Cox N,Pilling D,Gomer RH